Thomas Chadwick

Thomas Chadwick

Clinical Trials Statistician

Population Health Sciences Institute

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Andrew J Fisher, Michael White, Nicola Goudie, Anneka Kershaw, Julia Phillipson, Michelle Bardgett, Joanne Lally, Alex Bevin-Nicholls, Thomas Chadwick, Andrew Bryant, Sian Russell, Hesther Smith, Laura Frisby, Rebecca Errington, Martin Carby, Richard Thompson, Karthik Santhanakrishnan, Jasvir Parmar, James L Lordan, Luke Vale, Helen Hancock, Catherine Exley, Andrew R Gennery, James MS Wason (2024). Extracorporeal photopheresis (ECP) in the treatment of chronic lung allograft dysfunction (CLAD): a prospective, multicentre, open-label, randomised controlled trial studying the addition of ECP to standard care in the treatment of bilateral lung transplant patients with CLAD (E-CLAD UK). BMJ Open Respiratory Research.

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William King, Tara Homer, Chris Harding, Helen Mossop, Thomas Chadwick, Alaa Abouhajar, Luke Vale (2024). Cost-effectiveness of methenamine hippurate compared with antibiotic prophylaxis for the management of recurrent urinary tract infections in secondary care: a multicentre, open-label, randomised, non-inferiority trial. BMJ Open.

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Chris Harding, Thomas Chadwick, Tara Homer, Jan Lecouturier, Helen Mossop, Sonya Carnell, Will King, Alaa Abouhajar, Luke Vale, Gillian Watson, Rebecca Forbes, Stephanie Currer, Robert Pickard, Ian Eardley, Ian Pearce, Nikesh Thiruchelvam, Karen Guerrero, Katherine Walton, Zahid Hussain, Henry Lazarowicz, Ased Ali (2022). Methenamine hippurate compared with antibiotic prophylaxis to prevent recurrent urinary tract infections in women: the ALTAR non-inferiority RCT. Health Technology Assessment.

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Chris Harding, Helen Mossop, Tara Homer, Thomas Chadwick, William King, Sonya Carnell, Jan Lecouturier, Alaa Abouhajar, Luke Vale, Gillian Watson, Rebecca Forbes, Stephanie Currer, Robert Pickard, Ian Eardley, Ian Pearce, Nikesh Thiruchelvam, Karen Guerrero, Katherine Walton, Zahid Hussain, Henry Lazarowicz, Ased Ali (2022). Alternative to prophylactic antibiotics for the treatment of recurrent urinary tract infections in women: multicentre, open label, randomised, non-inferiority trial. BMJ.

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Azim L, Hindmarch P, Browne G, Chadwick T, Clare E, Courtney P, Dixon L, Duffelen N, Fouweather T, Geddes JR, Goudie N, Harvey S, Helter T, Holstein EM, Martin G, Mawson P, McCaffery J, Morriss R, Simon J, Smith D, Stokes PRA, Walker J, Weetman C, Wolstenhulme F, Young AH, Watson S, McAllister-Williams RH (2021). Study protocol for a randomised placebo-controlled trial of pramipexole in addition to mood stabilisers for patients with treatment resistant bipolar depression (the PAX-BD study). BMC Psychiatry 2021; 21:334.

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Forbes R, Ali A, Abouhajar A, Brennand C, Brown H, Carnell S, Chadwick T, Eardley I, Lecouturier J, Mossop H, Pearce I, Pickard R, Thiruchelvam N, Walton K, Wilkinson J, Harding C (2018). ALternatives To prophylactic Antibiotics for the treatment of Recurrent urinary tract infection in women (ALTAR): Study protocol for a multicentre, pragmatic, patient-randomised, non-inferiority trial. Trials 2018; 19:616.

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Fisher H, Oluboyede Y, Chadwick T, Abdel-Fattah M, Brennand C, Fader M, Harrison S, Hilton P, Larcombe J, Little P, McClurg D, McColl E, N'Dow J, Ternent L, Thiruchelvam N, Timoney A, Vale L, Walton K, von Wilamowitz-Moellendorff A, Wilkinson J, Wood R, Pickard R (2018). Continuous low-dose antibiotic prophylaxis for adults with repeated urinary tract infections (AnTIC): A randomised, open-label trial. Lancet Infect Dis 2018; 18:957-68.

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Pinder EM, Rostron AJ, Hellyer TP, Ruchaud-Sparagano M-H, Scott J, Macfarlane JG, Wiscombe S, Widdrington JD, Roy AI, Linnett VC, Baudouin SV, Wright SE, Chadwick T, Fouweather T, Juss JK, Chilvers ER, Bowett SA, Parker J, McAuley DF, Conway Morris A, Simpson AJ (2018). Randomised controlled trial of GM-CSF in critically ill patients with impaired neutrophil phagocytosis. Thorax 2018; 73:918-25.

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Pickard R, Chadwick T, Oluboyede Y, Brennand C, von Wilamowitz-Moellendorff A, McClurg D, Wilkinson J, Ternent L, Fisher H, Walton K, McColl E, Vale L, Wood R, Abdel-Fattah M, Hilton P, Fader M, Harrison S, Larcombe J, Little P, Timoney A, N'Dow J, Armstrong H, Morris N, Walker K, Thiruchelvam N (2018). Continuous low-dose antibiotic prophylaxis to prevent urinary tract infection in adults who perform clean intermittent self-catheterisation: The AnTIC RCT. Health Technol Assess 2018; 22.

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Wright SE, Thomas K, Watson G, Baker C, Bryant A, Chadwick TJ, Shen J, Wood R, Wilkinson J, Mansfield L, Stafford V, Wade C, Furneval J, Henderson A, Hugill K, Howard P, Roy A, Bonner S, Baudouin S (2017). Intensive versus standard physical rehabilitation therapy in the critically ill (EPICC): A multicentre, parallel-group, randomised controlled trial. Thorax 2018; 73:213-21.

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Bell GM, Anderson AE, Diboll J, Reece R, Eltherington O, Harry RA, Fouweather T, MacDonald C, Chadwick T, McColl E, Dunn J, Dickinson AM, Hilkens CMU, Isaacs JD (2017). Autologous tolerogenic dendritic cells for rheumatoid and inflammatory arthritis. Ann Rheum Dis 2017; 76:227-34.

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Payne B, Chadwick TJ, Blamire A, Anderson KN, Parikh J, Qian J, Hynes AM, Wilkinson J, Price DA (2017). Does efavirenz replacement improve neurological function in treated HIV infection?. HIV Med 2017; 18:690-5.

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Fisher A, Andreasson A, Chrysos A, Lally J, Mamasoula V, Exley C, Wilkinson J, Qian J, Watson G, Lewington O, Chadwick T, McColl E, Pearce M, Mann K (2016). An observational study of donor ex vivo lung perfusion in UK lung transplantation: DEVELOP-UK. Health Technol Assess 2016; 20.

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Brennand C, von Wilamowitz-Moellendorff A, Dunn S, Wilkinson J, Chadwick T, Ternent L, Oluboyede Y, Wood R, Walton K, Fader M, N'Dow J, Abdel-Fattah M, McClurg D, Little P, Hilton P, Timoney A, Morris N, Thiruchelvam N, Larcombe J, Harrison S, Armstrong H, McColl E, Pickard R (2016). Antibiotic treatment for intermittent bladder catheterisation with once daily prophylaxis (the AnTIC study): Study protocol for a randomised controlled trial. Trials 2016; 17:276.

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Aspray TJ, Francis RM, McColl E, Chadwick T, Stamp E, Prentice A, Schoenmakers I (2016). Vitamin D supplementation for 12 months in older people prevents bone loss and suppresses parathyroid hormone levels. Bone Abstracts 2016; 5:P221b.

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Payne B, Chadwick T, Blamire A, Qian J, Hynes AM, Wilkinson J, Price DA, Anderson K (2016). Neurocognitive and neurometabolic effects of switch from efavirenz to ritonavir-boosted lopinavir. HIV Med 2016; 17:14-71.

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Pinder EM, Rostron AJ, Hellyer TP, Ruchaud-Sparagano M-H, Scott J, Macfarlane JG, Wiscombe S, Widdrington JD, Allen T, Roy AI, Linnett VC, Baudouin SV, Wright SE, Chadwick T, Fouweather A, Bowett S, Parker J, Corris PA, McAuley DF, Morris AC, Simpson AJ (2016). Randomised controlled trial of granulocyte macrophage colony stimulating factor in critically ill patients with impaired neutrophil function. Am J Resp Crit Care 2016; 201:A2727.

Tan MP, Murray A, Hawkins T, Chadwick TJ, Kerr SRJ, Parry SW (2015). Cardiac Iodine-123-Meta-Iodo-Benzylguanidine uptake in carotid sinus hypersensitivity. PLoS ONE 2015; 10:e0126241.

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Thomas K, Wright SE, Watson G, Baker C, Stafford V, Wade C, Chadwick TJ, Mansfield L, Wilkinson J, Shen J, Deverill M, Bonner S, Hugill K, Howard P, Henderson A, Roy A, Furneval J, Baudouin SV (2015). Extra Physiotherapy in Critical Care (EPICC) trial protocol: A randomised controlled trial of intensive versus standard physical rehabilitation therapy in the critically ill. BMJ Open 2015; 5:e008035.

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Little SA, Leelarathna L, Walkinshaw E, Tan HK, Chapple O, Lubina-Solomon A, Chadwick TJ, Barendse S, Stocken DD, Brennand C, Marshall SM, Wood R, Speight J, Kerr D, Flanagan D, Heller SR, Evans ML, Shaw JAM (2014). Response to comment on Little et al. Recovery of hypoglycemia awareness in long-standing type 1 diabetes: A multicenter 2 × 2 factorial randomized controlled trial comparing insulin pump with multiple daily injections and continuous with conventional glucose self-monitoring (HypoCOMPaSS). Diabetes Care 2014;37:2114-2122. Diabetes Care 2014; 37:e272-3.

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