Luke Ouma

Luke Ouma

Research Associate

Population Health Sciences Institute

Biography

Background

Luke Ouma is a research associate in Biostatistics at the Biostatistics Research Group, Population Health Sciences Institute, Newcastle University, working with Prof James Wason.

His research focuses on statistical methodology for ‘precision medicine trials’, specifically focusing on developing improved methods for the design and analysis of Umbrella and Basket trials. He has previously worked as a statistician at the Kemri-Wellcome Trust Research Programme, Kenya.

Contact

Interests
  • Biostatistics
  • Clinical trials
  • Cancer research
Education

  • PhD Biostatistics

    Newcastle University

  • MSc Medical Statistics

    London School of Hygiene and Tropical Medicine

  • PgD Health Research Methods

    Pwani University, Kenya

  • BSc Statistics

    University of Nairobi, Kenya

Publications

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Leher Gumber, Opeyemi Agbeleye, Alex Inskip, Ross Fairbairn, Madeleine Still, Luke Ouma, Jingky Lozano-kuehne, Michelle Bardgett, John D Isaacs, James MS Wason, Dawn Craig, Arthur G Pratt (2024). Operational complexities in international clinical trials: a systematic review of challenges and proposed solutions. BMJ Open.

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Svetlana Cherlin, Theophile Bigirumurame, Michael J Grayling, Jérémie Nsengimana, Luke Ouma, Aida Santaolalla, Fang Wan, S Faye Williamson, James MS Wason (2023). Utilising high-dimensional data in randomised clinical trials: A review of methods and practice. Research Methods in Medicine & Health Sciences.

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Luke O. Ouma, Michael J. Grayling, James M. S. Wason, Haiyan Zheng (2022). Bayesian modelling strategies for borrowing of information in randomised basket trials. Journal of the Royal Statistical Society: Series C (Applied Statistics).

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Luke O. Ouma, James M. S. Wason, Haiyan Zheng, Nina Wilson, Michael Grayling (2022). Design and analysis of umbrella trials: Where do we stand?. Frontiers in Medicine.

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Grayling MJ, Bigirumurame T, Cherlin S, Ouma L, Zheng H, Wason J (2021). Innovative trial approaches in immune-mediated inflammatory diseases: Current use and future potential. BMC Rheumatol 2021; 5:21.

DOI

Ouma LO, Grayling MJ, Zheng H, Wason J (2021). Treatment allocation strategies for umbrella trials in the presence of multiple biomarkers: A comparison of methods. Pharm Stat 2021; doi:10.1002/pst.2119.

DOI