John Matthews

John Matthews

Emeritus Professor of Medical Statistics

School of Mathematics, Statistics and Physics

Biography

Background

I came to Newcastle University in 1987, following undergraduate and postgraduate studies in mathematics and statistics at Cambridge University, a PhD at the London School of Hygiene & Tropical Medicine with Professor Michael Healy and a post-doctoral appointment at Oxford University with Professor Peter Armitage.

I was awarded the Guy Medal in Bronze of the Royal Statistical Society in 1996 and served as President of the British and Irish Region of the International Biometric Society from 2014-16.

I retired from the university in 2022, becoming an Emeritus Professor. I remain involved in several projects and activities within the Biostatistics Research Group.

Teaching

  • MMB8100 Research Skills and Principles for the Biosciences
  • MAS3908 Experimental Design

Contact

Interests
  • Medical statistics
  • Clinical trials
  • Crossover trials
  • Design in medicine

Publications

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Heather Lambert, Shaun Hiu, Malcolm Coulthard, John N S Matthews, Ruth Wood, Jean Crosier, Rachel Agbeko, Thomas Brick, Heather Duncan, David Grant, Quen Mok, Andrew Gustaf Nyman, John Pappachan, Paul Wellman, Chris Boucher, Joe Bulmer, Denise Chisholm, Kirsten Cromie, Victoria Emmet, Richard Feltbower, Michael Grayling, Rebecca Harrison, Eva-Maria Holstein, Ciara A Kennedy, Elaine McColl, Kevin Morris, Lee Norman, Julie Office, Roger Parslow, Christine Pattinson, Shriya Sharma, Jonathan Smith, Alison Steel, Rachel Steel, Jayne Straker, Lamprini Vrana, Jenn Walker, Mike Whitaker, Jim Wightman, Nina Wilson, Lucy Wirz (2024). Evaluation of efficacy, outcomes and safety of infant haemodialysis and ultrafiltration in clinical use: I-KID a stepped wedge cluster RCT. Efficacy and Mechanism Evaluation.

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Heather Lambert, Shaun Hiu, Malcolm G. Coulthard, John N. S. Matthews, Eva-Maria Holstein, Jean Crosier, Rachel Agbeko, Thomas Brick, Heather Duncan, David Grant, Quen Mok, Andrew Gustaf Nyman, John Pappachan, Chris Boucher, Joe Bulmer, Denise Chisholm, Kirsten Cromie, Victoria Emmet, Richard G. Feltbower, Arunoday Ghose, Michael Grayling, Rebecca Harrison, Ciara A. Kennedy, Elaine McColl, Kevin Morris, Lee Norman, Julie Office, Roger Parslow, Christine Pattinson, Shriya Sharma, Jonathan Smith, Alison Steel, Rachel Steel, Jayne Straker, Lamprini Vrana, Jenn Walker, Paul Wellman, Mike Whitaker, Jim Wightman, Nina Wilson, Lucy Wirz, Ruth Wood (2023). The Infant KIdney Dialysis and Utrafiltration (I-KID) Study: A Stepped-Wedge Cluster-Randomized Study in Infants, Comparing Peritoneal Dialysis, Continuous Venovenous Hemofiltration, and Newcastle Infant Dialysis Ultrafiltration System, a Novel Infant Hemodialysis Device. Pediatric Critical Care Medicine.

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Tim D Cheetham, Michael Cole, Mario Abinun, Amit Allahabadia, Tim Barratt, Justin H Davies, Paul Dimitri, Amanda Drake, Zainaba Mohamed, Robert D Murray, Caroline A Steele, Nicola Zammitt, Sonya Carnell, Jonathan Prichard, Gillian Watson, Sophie Hambleton, John N S Matthews, Simon H S Pearce (2021). Adjuvant Rituximab—Exploratory Trial in Young People With Graves Disease. The Journal of Clinical Endocrinology & Metabolism.

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Heather J Lambert, Shriya Sharma, John N S Matthews (2021). I-KID study protocol: evaluation of efficacy, outcomes and safety of a new infant haemodialysis and ultrafiltration machine in clinical use: a randomised clinical investigation using a cluster stepped-wedge design. BMJ Paediatrics Open.

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Bradley J, Rowland MK, Matthews JNS, Adamson AJ, Spence S (2021). A comparison of food portion size estimation methods among 11–12 year olds: 3D food models vs an online tool using food portion photos (Intake24). BMC Nutr 2021; 7:10.

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Pippard BJ, Neal MA, Maunder AM, Hollingsworth KG, Biancardi A, Lawson RA, Fisher H, Matthews JNS, Simpson AJ, Wild JM, Thelwall PE (2021). Reproducibility of 19F‐MR ventilation imaging in healthy volunteers. Magn Reson Med 2021; 85:3343-52.

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Spence S, Matthews JNS, McSweeney L, Rowland MK, Orango P, Adamson AJ (2020). Implementation of Universal Infant Free School Meals: A pilot study in NE England exploring the impact on Key Stage 1 pupil's dietary intake. Public Health Nutr 2020; doi:10.1017/S1368980020004875.

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Matthews JNS (2020). Highly efficient stepped wedge designs for clusters of unequal size. Biometrics 2020; 76:1167-76.

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Spence S, Matthews JNS, McSweeney L, Rowland M, Orango P, Adamson AJ (2019). A natural experimental evaluation of the effect of universal infant free school meals on key stage 1 pupil′s dietary intake in northeast England: A pilot study. Lancet 2019; 394:S87.

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Kasza J, Hemming K, Hooper R, Matthews JNS, Forbes AB (2019). Impact of non-uniform correlation structure on sample size and power in multiple-period cluster randomised trials. Stat Methods Med Res 2019; 28:703-16.

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Matthews JNS, Forbes A (2017). Stepped wedge designs: Insights from a design of experiments perspective. Stat Med 2017; 36:3772-90.

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Manios Y, Moschonis G, Lambrinou CP, Mavrogianni C, Tsirigoti L, Hoeller U, Roos FF, Bendik I, Eggersdorfer M, Celis-Morales C, Livingstone KM, Marsaux CFM, Macready AL, Fallaize R, O'Donovan CB, Woolhead C, Forster H, Walsh MC, Navas-Carretero S, San-Cristobal R, Kolossa S, Hallmann J, Jarosz M, Surwiłło A, Traczyk I, Drevon CA, van Ommen B, Grimaldi K, Matthews JNS, Daniel H, Martinez JA, Lovegrove JA, Gibney ER, Brennan L, Saris WHM, Gibney M, Mathers JC (2017). Associations of vitamin D status with dietary intakes and physical activity levels among adults from seven European countries: The Food4Me study. Eur J Nutr 2017; 57:1357-68.

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Foster E, Hawkins A, Barton KL, Stamp E, Matthews JNS, Adamson AJ (2017). Development of food photographs for use with children aged 18 months to 16 years: Comparison against weighed food diaries – The Young Person's Food Atlas (UK). PLoS ONE 2017; 12:e0169084.

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Celis-Morales C, Livingstone KM, Marsaux CFM, Macready AL, Fallaize R, O'Donovan CB, Woolhead C, Forster H, Walsh MC, Navas-Carretero S, San-Cristobal R, Tsirigoti L, Lambrinou CP, Mavrogianni C, Moschonis G, Kolossa S, Hallmann J, Godlewska M, Surwiłło A, Traczyk I, Drevon CA, Bouwman J, van Ommen B, Grimaldi K, Parnell LD, Matthews JNS, Manios Y, Daniel H, Martinez JA, Lovegrove JA, Gibney ER, Brennan L, Saris WHM, Gibney M, Mathers JC (2016). Effect of personalized nutrition on health-related behaviour change: Evidence from the Food4me European randomized controlled trial. Int J Epidemiol 2016; 46:578-88.

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Matthews JNS (2016). Anticoagulation in haemodialysis in children: A thirty-period crossover trial. In Aston P et al (eds) UK Success Stories in Industrial Mathematics. Springer, Cham.

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Matthews JNS, Badi NH (2015). Inconsistent treatment estimates from mis‐specified logistic regression analyses of randomized trials. Stat Med 2015; 34:2681-94.

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Spence S, White M, Adamson AJ, Matthews JNS (2015). Does the use of passive or active consent affect consent or completion rates, or dietary data quality? Repeat cross-sectional survey among school children aged 11-12 years. BMJ Open 2015; 5:e006457.

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Celis-Morales C, Livingstone KM, Marsaux CFM, Forster H, O'Donovan CB, Woolhead C, Macready AL, Fallaize R, Navas-Carretero S, San-Cristobal R, Kolossa S, Hartwig K, Tsirigoti L, Lambrinou CP, Moschonis G, Godlewska M, Surwiłło A, Grimaldi K, Bouwman J, Daly EJ, Akujobi V, O'Riordan R, Hoonhout J, Claassen A, Hoeller U, Gundersen TE, Kaland SE, Matthews JNS, Manios Y, Traczyk I, Drevon CA, Gibney ER, Brennan L, Walsh MC, Lovegrove JA, Martinez JA, Saris WHM, Daniel H, Gibney M, Mathers JC (2014). Design and baseline characteristics of the Food4Me study: A web-based randomised controlled trial of personalised nutrition in seven European countries. Genes Nutr 2014; 10:450.

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Spence S, Delve J, Stamp E, Matthews JNS, White M, Adamson AJ (2014). Did school food and nutrient-based standards in England impact on 11–12y olds nutrient intake at lunchtime and in total diet? Repeat cross-sectional study. PLoS ONE 2014; 9:e112648.

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Coulthard MG, Lambert HJ, Vernon SJ, Hunter EW, Keir MJ, Matthews JNS (2013). Does prompt treatment of urinary tract infection in preschool children prevent renal scarring: Mixed retrospective and prospective audits. Arch Dis Child 2013; 99:342-7.

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