Faye Wolstenhulme, Irena Bibby, Michael Cole, Lydia Grixti, Naomi McGregor, Penny Bradley, Rebecca H Maier, Jenn Walker, Simon H Pearce, James Wason
(2024).
Graves-PCD: protocol for a randomised, dose-finding, adaptive trial of the plasma cell-depleting agent daratumumab in severe Graves’ disease.
BMJ Open.
Andrew J Fisher, Michael White, Nicola Goudie, Anneka Kershaw, Julia Phillipson, Michelle Bardgett, Joanne Lally, Alex Bevin-Nicholls, Thomas Chadwick, Andrew Bryant, Sian Russell, Hesther Smith, Laura Frisby, Rebecca Errington, Martin Carby, Richard Thompson, Karthik Santhanakrishnan, Jasvir Parmar, James L Lordan, Luke Vale, Helen Hancock, Catherine Exley, Andrew R Gennery, James MS Wason
(2024).
Extracorporeal photopheresis (ECP) in the treatment of chronic lung allograft dysfunction (CLAD): a prospective, multicentre, open-label, randomised controlled trial studying the addition of ECP to standard care in the treatment of bilateral lung transplant patients with CLAD (E-CLAD UK).
BMJ Open Respiratory Research.
Karen Yirmiya, Matthew Constantinou, Elizabeth Simes, Anthony Bateman, James Wason, Jessica Yakeley, Mary McMurran, Mike Crawford, Alison Frater, Paul Moran, Barbara Barrett, Angus Cameron, Zoe Hoare, Elizabeth Allison, Stephen Pilling, Stephen Butler, Peter Fonagy
(2024).
The mediating role of reflective functioning and general psychopathology in the relationship between childhood conduct disorder and adult aggression among offenders.
Psychological Medicine.
Nicola J Wyatt, Hannah Watson, Carl A Anderson, Nicholas A Kennedy, Tim Raine, Tariq Ahmad, Dean Allerton, Michelle Bardgett, Emma Clark, Dawn Clewes, Cristina Cotobal Martin, Mary Doona, Jennifer A Doyle, Katherine Frith, Helen C Hancock, Ailsa L Hart, Victoria Hildreth, Peter M Irving, Sameena Iqbal, Ciara Kennedy, Andrew King, Sarah Lawrence, Charlie W Lees, Robert Lees, Laura Letchford, Trevor Liddle, James O Lindsay, Rebecca H Maier, John C Mansfield, Julian R Marchesi, Naomi McGregor, Rebecca E McIntyre, Jasmin Ostermayer, Tolulope Osunnuyi, Nick Powell, Natalie J Prescott, Jack Satsangi, Shriya Sharma, Tara Shrestha, Ally Speight, Michelle Strickland, James MS Wason, Kevin Whelan, Ruth Wood, Gregory R Young, Xinyue Zhang, Miles Parkes, Christopher J Stewart, Luke Jostins-Dean, Christopher A Lamb
(2024).
Defining predictors of responsiveness to advanced therapies in Crohn’s disease and ulcerative colitis: protocol for the IBD-RESPONSE and nested CD-metaRESPONSE prospective, multicentre, observational cohort study in precision medicine.
BMJ Open.
Leher Gumber, Opeyemi Agbeleye, Alex Inskip, Ross Fairbairn, Madeleine Still, Luke Ouma, Jingky Lozano-kuehne, Michelle Bardgett, John D Isaacs, James MS Wason, Dawn Craig, Arthur G Pratt
(2024).
Operational complexities in international clinical trials: a systematic review of challenges and proposed solutions.
BMJ Open.
Suraiya Dubash, Tara D. Barwick, Kasia Kozlowski, Andrea G. Rockall, Sairah Khan, Sameer Khan, Siraj Yusuf, Angela Lamarca, Juan W. Valle, Richard A. Hubner, Mairéad G. McNamara, Andrea Frilling, Tricia Tan, Florian Wernig, Jeannie Todd, Karim Meeran, Bhavesh Pratap, Saleem Azeem, Michael Huiban, Nicholas Keat, Jingky P. Lozano-Kuehne, Eric O. Aboagye, Rohini Sharma
(2024).
Somatostatin Receptor Imaging with [18F]FET-βAG-TOCA PET/CT and [68Ga]Ga-DOTA-Peptide PET/CT in Patients with Neuroendocrine Tumors: A Prospective, Phase 2 Comparative Study.
Journal of Nuclear Medicine.
Heather Lambert, Shaun Hiu, Malcolm Coulthard, John N S Matthews, Ruth Wood, Jean Crosier, Rachel Agbeko, Thomas Brick, Heather Duncan, David Grant, Quen Mok, Andrew Gustaf Nyman, John Pappachan, Paul Wellman, Chris Boucher, Joe Bulmer, Denise Chisholm, Kirsten Cromie, Victoria Emmet, Richard Feltbower, Michael Grayling, Rebecca Harrison, Eva-Maria Holstein, Ciara A Kennedy, Elaine McColl, Kevin Morris, Lee Norman, Julie Office, Roger Parslow, Christine Pattinson, Shriya Sharma, Jonathan Smith, Alison Steel, Rachel Steel, Jayne Straker, Lamprini Vrana, Jenn Walker, Mike Whitaker, Jim Wightman, Nina Wilson, Lucy Wirz
(2024).
Evaluation of efficacy, outcomes and safety of infant haemodialysis and ultrafiltration in clinical use: I-KID a stepped wedge cluster RCT.
Efficacy and Mechanism Evaluation.
Frances Varian, Jennifer Dick, Christian Battersby, Stefan Roman, Jenna Ablott, Lisa Watson, Sarah Binmahfooz, Hamza Zafar, Gerry Colgan, John Cannon, Jay Suntharalingam, Jim Lordan, Luke Howard, Colm McCabe, John Wort, Laura Price, Colin Church, Neil Hamilton, Iain Armstrong, Abdul Hameed, Judith Hurdman, Charlie Elliot, Robin Condliffe, Martin Wilkins, Alastair Webb, David Adlam, Ray L. Benza, Kazem Rahimi, Mohadeseh Shojaei‐Shahrokhabadi, Nan X. Lin, James M. S. Wason, Alasdair McIntosh, Alex McConnachie, Jennifer T. Middleton, Roger Thompson, David G. Kiely, Mark Toshner, Alexander Rothman
(2024).
Pulmonary Hypertension: Intensification and Personalization of Combination Rx (PHoenix): A phase IV randomized trial for the evaluation of dose‐response and clinical efficacy of riociguat and selexipag using implanted technologies.
Pulmonary Circulation.
Janet A Wilson, Tony Fouweather, Deborah D Stocken, Tara Homer, Catherine Haighton, Nikki Rousseau, James O’Hara, Luke Vale, Rebecca Wilson, Sonya Carnell, Scott Wilkes, Jill Morrison, Kim Ah-See, Sean Carrie, Claire Hopkins, Nicola Howe, Musheer Hussain, Lyndsay Lindley, Kenneth MacKenzie, Lorraine McSweeney, Hisham Mehanna, Christopher Raine, Ruby Smith Whelan, Frank Sullivan, Alexander von Wilamowitz-Moellendorff, Dawn Teare
(2023).
Tonsillectomy compared with conservative management in patients over 16 years with recurrent sore throat: the NATTINA RCT and economic evaluation.
Health Technology Assessment.
Vicky Brocklebank, Patrick R. Walsh, Kate Smith-Jackson, Thomas M. Hallam, Kevin J. Marchbank, Valerie Wilson, Theophile Bigirumurame, Tina Dutt, Emma K. Montgomery, Michal Malina, Edwin K. S. Wong, Sally Johnson, Neil S. Sheerin, David Kavanagh
(2023).
Atypical hemolytic uremic syndrome in the era of terminal complement inhibition: an observational cohort study.
Blood.
Sean Carrie, James O’Hara, Tony Fouweather, Tara Homer, Nikki Rousseau, Leila Rooshenas, Alison Bray, Deborah D Stocken, Laura Ternent, Katherine Rennie, Emma Clark, Nichola Waugh, Alison J Steel, Jemima Dooley, Michael Drinnan, David Hamilton, Kelly Lloyd, Yemi Oluboyede, Caroline Wilson, Quentin Gardiner, Naveed Kara, Sadie Khwaja, Samuel C Leong, Sangeeta Maini, Jillian Morrison, Paul Nix, Janet A Wilson, M Dawn Teare
(2023).
Clinical effectiveness of septoplasty versus medical management for nasal airways obstruction: multicentre, open label, randomised controlled trial.
BMJ.
Martin Law, Dominique-Laurent Couturier, Babak Choodari-Oskooei, Phillip Crout, Carrol Gamble, Peter Jacko, Philip Pallmann, Mark Pilling, David S. Robertson, Michael Robling, Matthew R. Sydes, Sofía S. Villar, James Wason, Graham Wheeler, S. Faye Williamson, Christina Yap, Thomas Jaki
(2023).
Medicines and Healthcare products Regulatory Agency’s “Consultation on proposals for legislative changes for clinical trials”: a response from the Trials Methodology Research Partnership Adaptive Designs Working Group, with a focus on data sharing.
Trials.
Marjan Nouri-Keshtkar, Mohadeseh Shojaei Shahrokhabadi, Azadeh Ghaheri, Roya Hosseini, Hassan Ketabi, Mojtaba Farjam, Ding-Geng Chen, Mehdi Rezaeian, Reza Homayounfar, Yaser Tahamtani, Mehdi Totonchi
(2023).
Role of gender in explaining metabolic syndrome risk factors in an Iranian rural population using structural equation modelling.
Scientific Reports.
Miranda Morton, Nina Wilson, Tara Marie Homer, Laura Simms, Alison Steel, Rebecca Maier, James Wason, Laura Ternent, Alaa Abouhajar, Maria Allen, Richard Joyce, Victoria Hildreth, Rachel Lakey, Svetlana Cherlin, Adam Walker, Graham Devereux, James D Chalmers, Adam T Hill, Charles Haworth, John R Hurst, Anthony De Soyza
(2023).
Dual bronchodilators in Bronchiectasis study (DIBS): protocol for a pragmatic, multicentre, placebo-controlled, three-arm, double-blinded, randomised controlled trial studying bronchodilators in preventing exacerbations of bronchiectasis.
BMJ Open.
Mohita Tagore, Emiliano Hergenreder, Sarah C. Perlee, Nelly M. Cruz, Laura Menocal, Shruthy Suresh, Eric Chan, Maayan Baron, Stephanie Melendez, Asim Dave, Walid K. Chatila, Jérémie Nsengimana, Richard P. Koche, Travis J. Hollmann, Trey Ideker, Lorenz Studer, Andrea Schietinger, Richard M. White
(2023).
GABA Regulates Electrical Activity and Tumor Initiation in Melanoma.
Cancer Discovery.
Janet A Wilson, James O’Hara, Tony Fouweather, Tara Homer, Deborah D Stocken, Luke Vale, Catherine Haighton, Nikki Rousseau, Rebecca Wilson, Lorraine McSweeney, Scott Wilkes, Jill Morrison, Kenneth MacKenzie, Kim Ah-See, Sean Carrie, Claire Hopkins, Nicola Howe, Musheer Hussain, Hisham Mehanna, Christopher Raine, Frank Sullivan, Alexander von Wilamowitz-Moellendorff, M Dawn Teare
(2023).
Conservative management versus tonsillectomy in adults with recurrent acute tonsillitis in the UK (NATTINA): a multicentre, open-label, randomised controlled trial.
The Lancet.
Paula Cunnea, Edward W. Curry, Elizabeth L. Christie, Katherine Nixon, Chun Hei Kwok, Ahwan Pandey, Ratri Wulandari, Kerstin Thol, Jennifer Ploski, Cristina Morera-Albert, Stephen McQuaid, Jingky Lozano-kuehne, James J. Clark, Jonathan Krell, Euan A. Stronach, Iain A. McNeish, David D.L. Bowtell, Christina Fotopoulou
(2023).
Spatial and temporal intra-tumoral heterogeneity in advanced HGSOC: Implications for surgical and clinical outcomes.
Cell Reports Medicine.
Mark Lythgoe, Paola Dama, Adam Enver Frampton, Emily Pickford, Laura Tookman, Paula Cunnea, Christina Fotopoulou, Daniel Liu, James Clark, Jingky Lozano-kuehne, Philip David Badman, Aaron Clarke, Sasha Chetal, Gayle Fyvie, Alex Stevenson, Jonathan Krell
(2023).
Immune modulation and the oral live biotherapeutic product, MRx0518, in treatment-naïve patients with cancer: Updated safety data..
Journal of Clinical Oncology.
Mark E. McClure, Seerapani Gopaluni, James Wason, Robert B. Henderson, Andre Van Maurik, Caroline C.O. Savage, Charles D. Pusey, Alan D. Salama, Paul A. Lyons, Jacinta Lee, Kim Mynard, David R. Jayne, Rachel B. Jones
(2023).
A randomised study of rituximab and belimumab sequential therapy in PR3 ANCA-associated vasculitis (COMBIVAS): design of the study protocol.
Trials.
Barry Wright, Ellen Kingsley, Cindy Cooper, Katie Biggs, Matthew Bursnall, Han-I Wang, Tim Chater, Elizabeth Coates, M Dawn Teare, Kirsty McKendrick, Gina Gomez de la Cuesta, Amy Barr, Kiera Solaiman, Anna Packham, David Marshall, Danielle Varley, Roshanak Nekooi, Steve Parrott, Shehzad Ali, Simon Gilbody, Ann Le Couteur
(2023).
I-SOCIALISE: Results from a cluster randomised controlled trial investigating the social competence and isolation of children with autism taking part in LEGO® based therapy (‘Play Brick Therapy’) clubs in school environments.
Autism.
Heather Lambert, Shaun Hiu, Malcolm G. Coulthard, John N. S. Matthews, Eva-Maria Holstein, Jean Crosier, Rachel Agbeko, Thomas Brick, Heather Duncan, David Grant, Quen Mok, Andrew Gustaf Nyman, John Pappachan, Chris Boucher, Joe Bulmer, Denise Chisholm, Kirsten Cromie, Victoria Emmet, Richard G. Feltbower, Arunoday Ghose, Michael Grayling, Rebecca Harrison, Ciara A. Kennedy, Elaine McColl, Kevin Morris, Lee Norman, Julie Office, Roger Parslow, Christine Pattinson, Shriya Sharma, Jonathan Smith, Alison Steel, Rachel Steel, Jayne Straker, Lamprini Vrana, Jenn Walker, Paul Wellman, Mike Whitaker, Jim Wightman, Nina Wilson, Lucy Wirz, Ruth Wood
(2023).
The Infant KIdney Dialysis and Utrafiltration (I-KID) Study: A Stepped-Wedge Cluster-Randomized Study in Infants, Comparing Peritoneal Dialysis, Continuous Venovenous Hemofiltration, and Newcastle Infant Dialysis Ultrafiltration System, a Novel Infant Hemodialysis Device.
Pediatric Critical Care Medicine.
Toshi A Furukawa, Aran Tajika, Masatsugu Sakata, Yan Luo, Rie Toyomoto, Masaru Horikoshi, Tatsuo Akechi, Norito Kawakami, Takeo Nakayama, Naoki Kondo, Shingo Fukuma, Hisashi Noma, Helen Christensen, Ronald C Kessler, Pim Cuijpers, James M S Wason
(2023).
Four 2×2 factorial trials of smartphone CBT to reduce subthreshold depression and to prevent new depressive episodes among adults in the community–RESiLIENT trial (Resilience Enhancement with Smartphone in LIving ENvironmenTs): a master protocol.
BMJ Open.
Nuredin I. Mohammed, James Wason, Thomas Mendy, Stefan A. Nass, Ogochukwu Ofordile, Famalang Camara, Bakary Baldeh, Chilel Sanyang, Amadou T. Jallow, Ilias Hossain, Nuno Faria, Jonathan J. Powell, Andrew M. Prentice, Dora I.A. Pereira
(2023).
A novel nano-iron supplement versus standard treatment for iron deficiency anaemia in children 6–35 months (IHAT-GUT trial): a double-blind, randomised, placebo-controlled non-inferiority phase II trial in The Gambia.
eClinicalMedicine.
David Winston Hamilton, James O’Hara, Amarkumar Rajgor, Gerald Selby, Mhairi Anderson, Kim Keltie, Rosalyn Parker, Dawn Teare, Joanne Patterson, Terry M Jones, Linda Sharp
(2023).
Precision medicine in laryngeal cancer: protocol of the laryngeal cancer cohort (LARCH).
BMJ Open.
Michael Nugent, Valerie Bryant, Chrissie Butcher, Holly Fisher, Sean Gill, Rebecca Goranova, Shaun Hiu, Lyndsay Lindley, James O’Hara, Yemi Oluboyede, Joanne Patterson, Tim Rapley, Tomos Robinson, Nikki Rousseau, Vicky Ryan, Ramkumar Shanmugasundaram, Linda Sharp, Ruby Smith Whelan, Deborah D Stocken, Laura Ternent, Janet Wilson, Jenn Walker
(2022).
Photobiomodulation in the management of oral mucositis for adult head and neck cancer patients receiving irradiation: the LiTEFORM RCT.
Health Technology Assessment.
Barry Wright, Lucy Tindall, Alexander J Scott, Ellen Lee, Katie Biggs, Cindy Cooper, Penny Bee, Han-I Wang, Lina Gega, Emily Hayward, Kiera Solaiman, M Dawn Teare, Thompson Davis, Karina Lovell, Jon Wilson, Dean McMillan, Amy Barr, Hannah Edwards, Jennifer Lomas, Chris Turtle, Steve Parrott, Catarina Teige, Tim Chater, Rebecca Hargate, Shehzad Ali, Sarah Parkinson, Simon Gilbody, David Marshall
(2022).
One-session treatment compared with multisession CBT in children aged 7–16 years with specific phobias: the ASPECT non-inferiority RCT.
Health Technology Assessment.
Alaa Abouhajar, Lisa Alcock, Theophile Bigirumurame, Penny Bradley, Laura Brown, Ian Campbell, Silvia Del Din, Julie Faitg, Gavin Falkous, Gráinne S. Gorman, Rachel Lakey, Robert McFarland, Jane Newman, Lynn Rochester, Vicky Ryan, Hesther Smith, Alison Steel, Renae J. Stefanetti, Huizhong Su, Robert W. Taylor, Naomi J. P. Thomas, Helen Tuppen, Amy E. Vincent, Charlotte Warren, Gillian Watson
(2022).
Acipimox in Mitochondrial Myopathy (AIMM): study protocol for a randomised, double-blinded, placebo-controlled, adaptive design trial of the efficacy of acipimox in adult patients with mitochondrial myopathy.
Trials.
C. Fiorella Murillo Perez, Holly Fisher, Shaun Hiu, Dorcas Kareithi, Femi Adekunle, Tracy Mayne, Elizabeth Malecha, Erik Ness, Adriaan J. van der Meer, Willem J. Lammers, Palak J. Trivedi, Pier Maria Battezzati, Frederik Nevens, Kris V. Kowdley, Tony Bruns, Nora Cazzagon, Annarosa Floreani, Andrew L. Mason, Albert Parés, Maria-Carlota Londoño, Pietro Invernizzi, Marco Carbone, Ana Lleo, Marlyn J. Mayo, George N. Dalekos, Nikolaos K. Gatselis, Xavier Verhelst, Aliya Gulamhusein, Harry L. A. Janssen, Rachel Smith, Steve Flack, Victoria Mulcahy, Michael Trauner, Christopher L. Bowlus, Keith D. Lindor, Christophe Corpechot, Gideon M. Hirschfield, James Wason, Bettina E. Hansen, Richard Sturgess, Christopher Healey, Anton Gunasekera, Yiannis Kallis, Gavin Wright, Thiriloganathan Mathialahan, Richard Evans, Jaber Gasem, David Ramanaden, Emma Ward, Mahesh Bhalme, Paul Southern, James Maggs, Mohamed Yousif, George Mells, Brijesh Srivastava, Matthew Foxton, Carole Collins, Yash Prasad, Francisco Porras-Perez, Tom Yapp, Minesh Patel, Roland Ede, Martyn Carte, Konrad Koss, Prayman Sattianayagam, Charles Grimley, Jude Tidbury, Dina Mansour, Matilda Beckley, Coral Hollywood, John Ramag, Harriet Gordon, Joanne Ridpath, Bob Grover, George Abouda, Ian Rees, Mark Narain, Imroz Salam, Paul Banim, Debasish Das, Helen Matthews, Faiyaz Mohammed, Rebecca Jones, Sambit Sen, George Bird, Martin Prince, Geeta Prasad, Paul Kitchen, John Hutchinson, Prakash Gupta, David Jones, Amir Shah, Subrata Saha, Katharine Pollock, Stephen Barclay, Natasha McDonald, Simon Rushbrook, Robert Przemioslo, Andrew Millar, Steven Mitchell, Andrew Davis, Asifabbas Naqvi, Tom Lee, Stephen Ryder, Jane Collier, Matthew Cramp, Richard Aspinal, Jonathan Booth, Earl Williams, Hyder Hussaini, John Christie, Tehreem Chaudhry, Douglas Thorburn, Stephen Mann, Aftab Ala, Julia Maltby, Chris Corbett, Saket Singhal, Barbara Hoeroldt, Jeff Butterworth, Andrew Douglas, Rohit Sinha, Simon Panter, Jeremy Shearman, Gary Bray, Michael Roberts, Daniel Forton, Nicola Taylor, Wisam Jafar, Matthew Cowan, Chin Lye Ch′ng, Mesbah Rahman, Emma Wesley, Sanjiv Jain, Aditya Mandal, Mark Wright, Palak Trivedi, Fiona Gordon, Esther Unitt, Andrew Austin, Altaf Palegwala, Vishwaraj Vemala, Andrew Higham, Jocelyn Fraser, Andy Li, Subramaniam Ramakrishnan, Alistair King, Simon Whalley, Ian Gee, Richard Keld, Helen Fellows, James Gotto, Charles Millson
(2022).
Greater Transplant-Free Survival in Patients Receiving Obeticholic Acid for Primary Biliary Cholangitis in a Clinical Trial Setting Compared to Real-World External Controls.
Gastroenterology.
Han-I. Wang, Barry Wright, Lucy Tindall, Cindy Cooper, Katie Biggs, Ellen Lee, M. Dawn Teare, Lina Gega, Alexander J. Scott, Emily Hayward, Kiera Solaiman, Thompson Davis, Dean McMillan, Simon Gilbody, Steve Parrott
(2022).
Cost and effectiveness of one session treatment (OST) for children and young people with specific phobias compared to multi-session cognitive behavioural therapy (CBT): results from a randomised controlled trial.
BMC Psychiatry.
Barry Wright, Lucy Tindall, Alexander J. Scott, Ellen Lee, Cindy Cooper, Katie Biggs, Penny Bee, Han-I Wang, Lina Gega, Emily Hayward, Kiera Solaiman, M. Dawn Teare, Thompson Davis, Jon Wilson, Karina Lovell, Dean McMillan, Amy Barr, Hannah Edwards, Jennifer Lomas, Chris Turtle, Steve Parrott, Catarina Teige, Tim Chater, Rebecca Hargate, Shezhad Ali, Sarah Parkinson, Simon Gilbody, David Marshall
(2022).
One session treatment (OST) is equivalent to multi-session cognitive behavioral therapy (CBT) in children with specific phobias (ASPECT): results from a national non-inferiority randomized controlled trial.
Journal of Child Psychology and Psychiatry.
James M. S. Wason, Munyaradzi Dimairo, Katie Biggs, Sarah Bowden, Julia Brown, Laura Flight, Jamie Hall, Thomas Jaki, Rachel Lowe, Philip Pallmann, Mark A. Pilling, Claire Snowdon, Matthew R. Sydes, Sofía S. Villar, Christopher J. Weir, Nina Wilson, Christina Yap, Helen Hancock, Rebecca Maier
(2022).
Practical guidance for planning resources required to support publicly-funded adaptive clinical trials.
BMC Medicine.
Giang Nguyen, Louise Hayes, Lem Ngongalah, Theophile Bigirumurame, Laura Gaudet, Adefisayo Odeniyi, Angela Flynn, Lisa Crowe, Becky Skidmore, Alexandre Simon, Vikki Smith, Nicola Heslehurst
(2022).
Association between maternal adiposity measures and infant health outcomes: A systematic review and meta-analysis.
Obesity Reviews.
Fulvio Zaccagna, Mary A. McLean, James T. Grist, Joshua Kaggie, Richard Mair, Frank Riemer, Ramona Woitek, Andrew B. Gill, Surrin Deen, Charlie J. Daniels, Stephan Ursprung, Rolf F. Schulte, Kieren Allinson, Anita Chhabra, Marie-Christine Laurent, Matthew Locke, Amy Frary, Sarah Hilborne, Ilse Patterson, Bruno D. Carmo, Rhys Slough, Ian Wilkinson, Bristi Basu, James Wason, Jonathan H. Gillard, Tomasz Matys, Colin Watts, Stephen J. Price, Thomas Santarius, Martin J. Graves, Sarah Jefferies, Kevin M. Brindle, Ferdia A. Gallagher
(2022).
Imaging Glioblastoma Metabolism by Using Hyperpolarized [1-$łess$sup$greater$13$łess$/sup$greater$C]Pyruvate Demonstrates Heterogeneity in Lactate Labeling: A Proof of Principle Study.
Radiology: Imaging Cancer.
Katherine J Rennie, Miles Witham, Penny Bradley, Andrew Clegg, Stephen Connolly, Helen C Hancock, Shaun Hiu, Leanne Marsay, Claire McDonald, Laura Robertson, Laura Simms, Alison J Steel, Claire J Steves, Bryony Storey, James Wason, Nina Wilson, Thomas von Zglinicki, Avan A P Sayer
(2022).
MET-PREVENT: metformin to improve physical performance in older people with sarcopenia and physical prefrailty/frailty – protocol for a double-blind, randomised controlled proof-of-concept trial.
BMJ Open.
Preetha Aravind, Sanjay Popat, Tara D. Barwick, Neil Soneji, Mark Lythgoe, Jingky Lozano-kuehne, Katherina Bernadette Sreter, Mattias Bergqvist, Neva H. Patel, Eric O. Aboagye, Laura M. Kenny
(2022).
[$łess$sup$greater$18$łess$/sup$greater$F]Fluorothymidine(FLT)-PET imaging of thymidine kinase 1 pharmacodynamics in non-small cell lung cancer treated with pemetrexed..
Journal of Clinical Oncology.
Tracey Bywater, Vashti Berry, Sarah Blower, Matthew Bursnall, Edward Cox, Amanda Mason-Jones, Sinéad McGilloway, Kirsty McKendrick, Siobhan Mitchell, Kate Pickett, Gerry Richardson, Kiera Solaiman, M Dawn Teare, Simon Walker, Karen Whittaker
(2022).
A proportionate, universal parenting programme to enhance social-emotional well-being in infants and toddlers in England: the E-SEE Steps RCT.
Public Health Research.
Chiara Grasso, Maja Popovic, Elena Isaevska, Fulvio Lazzarato, Valentina Fiano, Daniela Zugna, John Pluta, Benita Weathers, Kurt D′Andrea, Kristian Almstrup, Lynn Anson-Cartwright, D. Timothy. Bishop, Stephen J. Chanock, Chu Chen, Victoria K. Cortessis, Marlene D. Dalgaard, Siamak Daneshmand, Alberto Ferlin, Carlo Foresta, Megan N. Frone, Marija Gamulin, Jourik A. Gietema, Mark H. Greene, Tom Grotmol, Robert J. Hamilton, Trine B. Haugen, Russ Hauser, Robert Karlsson, Lambertus A. Kiemeney, Davor Lessel, Patrizia Lista, Ragnhild A. Lothe, Chey Loveday, Coby Meijer, Kevin T. Nead, Jérémie Nsengimana, Rolf I. Skotheim, Clare Turnbull, David J. Vaughn, Fredrik Wiklund, Tongzhang Zheng, Andrea Zitella, Stephen M. Schwartz, Katherine A. McGlynn, Peter A. Kanetsky, Katherine L. Nathanson, Lorenzo Richiardi
(2022).
Association study between polymorphisms in DNA methylation-related genes and testicular germ cell tumor risk.
Cancer Epidemiology, Biomarkers &$mathsemicolon$ Prevention.
R. C. Coombes, P. D. Badman, J. P. Lozano-Kuehne, X. Liu, I. R. Macpherson, I. Zubairi, R. D. Baird, N. Rosenfeld, J. Garcia-Corbacho, N. Cresti, R. Plummer, A. Armstrong, R. Allerton, D. Landers, H. Nicholas, L. McLellan, A. Lim, F. Mouliere, O. E. Pardo, M. J. Seckl
(2022).
Results of the phase IIa RADICAL trial of the FGFR inhibitor AZD4547 in endocrine resistant breast cancer.
Nature Communications.
Laura M. Kenny, Fiona J Gilbert, Gosala Gopalakrishnan, Preetha Aravind, Tara Barwick, Neva Patel, Duncan ROBERT Hiscock, Istvan Boros, Steven Kealey, Franklin I Aigbirhio, Jingky Lozano-kuehne, Susan Jane Cleator, Ben Fleming, Pippa Riddle, Rizvana Ahmad, Sue Chua, Stephen R. D. Johnston, Janine Mansi, Gary J. Cook, Eric O. Aboagye
(2022).
The HERPET study: Imaging HER2 expression in breast cancer with the novel PET tracer [$łess$sup$greater$18$łess$/sup$greater$F]GE-226, a first-in-patient study..
Journal of Clinical Oncology.
Masatsugu Sakata, Rie Toyomoto, Kazufumi Yoshida, Yan Luo, Yukako Nakagami, Teruhisa Uwatoko, Tomonari Shimamoto, Aran Tajika, Hidemichi Suga, Hiroshi Ito, Michihisa Sumi, Takashi Muto, Masataka Ito, Hiroshi Ichikawa, Masaya Ikegawa, Nao Shiraishi, Takafumi Watanabe, Ethan Sahker, Yusuke Ogawa, Steven D Hollon, Linda M Collins, Edward R Watkins, James Wason, Hisashi Noma, Masaru Horikoshi, Taku Iwami, Toshi A Furukawa
(2022).
Components of smartphone cognitive-behavioural therapy for subthreshold depression among 1093 university students: a factorial trial.
Evidence Based Mental Health.
Shelley Dua, Monica Ruiz-Garcia, Simon Bond, James Dowey, Stephen R. Durham, Ian Kimber, Clare Mills, Graham Roberts, Isabel Skypala, James Wason, Pamela Ewan, Robert J. Boyle, Andrew Clark
(2022).
Effects of Exercise and Sleep Deprivation on Reaction Severity During Oral Peanut Challenge: A Randomized Controlled Trial.
The Journal of Allergy and Clinical Immunology: In Practice.
Chris Harding, Thomas Chadwick, Tara Homer, Jan Lecouturier, Helen Mossop, Sonya Carnell, Will King, Alaa Abouhajar, Luke Vale, Gillian Watson, Rebecca Forbes, Stephanie Currer, Robert Pickard, Ian Eardley, Ian Pearce, Nikesh Thiruchelvam, Karen Guerrero, Katherine Walton, Zahid Hussain, Henry Lazarowicz, Ased Ali
(2022).
Methenamine hippurate compared with antibiotic prophylaxis to prevent recurrent urinary tract infections in women: the ALTAR non-inferiority RCT.
Health Technology Assessment.
Chris Harding, Helen Mossop, Tara Homer, Thomas Chadwick, William King, Sonya Carnell, Jan Lecouturier, Alaa Abouhajar, Luke Vale, Gillian Watson, Rebecca Forbes, Stephanie Currer, Robert Pickard, Ian Eardley, Ian Pearce, Nikesh Thiruchelvam, Karen Guerrero, Katherine Walton, Zahid Hussain, Henry Lazarowicz, Ased Ali
(2022).
Alternative to prophylactic antibiotics for the treatment of recurrent urinary tract infections in women: multicentre, open label, randomised, non-inferiority trial.
BMJ.
Carolina Castaneda-Garcia, Vivek Iyer, Jérémie Nsengimana, Adam Trower, Alastair Droop, Kevin M Brown, Jiyeon Choi, Tongwu Zhang, Mark Harland, Julia A Newton-Bishop, D Timothy Bishop, David J Adams, Mark M Iles, Carla Daniela Robles-Espinoza
(2022).
Defining novel causal SNPs and linked phenotypes at melanoma-associated loci.
Human Molecular Genetics.
Vivien Li, Baptiste Leurent, Frederik Barkhof, Marie Braisher, Fay Cafferty, Olga Ciccarelli, Arman Eshaghi, Emma Gray, Jennifer M. Nicholas, Mahesh Parmar, Guy Peryer, Jenny Robertson, Nigel Stallard, James Wason, Jeremy Chataway
(2022).
Designing Multi-arm Multistage Adaptive Trials for Neuroprotection in Progressive Multiple Sclerosis.
Neurology.
Debora D'Angelo Papaiz, Flávia Eichemberger Rius, Ana Luísa Pedroso Ayub, Clarice S. Origassa, Hemant Gujar, Diogo de Oliveira Pessoa, Eduardo Moraes Reis, Jérémie Nsengimana, Julia Newton-Bishop, Christopher E. Mason, Daniel J. Weisenberger, Gangning Liang, Miriam Galvonas Jasiulionis
(2022).
Genes regulated by DNA methylation are involved in distinct phenotypes during melanoma progression and are prognostic factors for patients.
Molecular Oncology.
Han-I Wang, Barry Debenham Wright, Matthew Bursnall, Cindy Cooper, Ellen Kingsley, Ann Le Couteur, Dawn Teare, Katie Biggs, Kirsty McKendrick, Gina Gomez de la Cuesta, Tim Chater, Amy Barr, Kiera Solaiman, Anna Packham, David Marshall, Danielle Varley, Roshanak Nekooi, Simon Gilbody, Steve Parrott
(2022).
Cost-utility analysis of LEGO based therapy for school children and young people with autism spectrum disorder: results from a randomised controlled trial.
BMJ Open.
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The FiCTION trial: Child oral health-related quality of life and dental anxiety across three treatment strategies for managing caries in young children.
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Mendelian Randomization and mediation analysis of leukocyte telomere length and risk of lung and head and neck cancers.
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Continuous low-dose antibiotic prophylaxis to prevent urinary tract infection in adults who perform clean intermittent self-catheterisation: The AnTIC RCT.
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The impact of autoimmune hepatitis and its treatment on health utility.
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Gastrostomy versus nasogastric tube feeding for chemoradiation patients with head and neck cancer: The TUBE pilot RCT.
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Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population.
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Large-scale sequencing of testicular germ cell tumour (TGCT) cases excludes major TGCT predisposition gene.
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Multisystemic therapy versus management as usual in the treatment of adolescent antisocial behaviour (START): A pragmatic, randomised controlled, superiority trial.
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Training nurses in a competency framework to support adults with epilepsy and intellectual disability: The EpAID cluster RCT.
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A screen for combination therapies in BRAF/NRAS wild type melanoma identifies nilotinib plus MEK inhibitor as a synergistic combination.
bioRxiv 2017; DOI:10.1101/195354.
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Detection of early subclinical lung disease in children with cystic fibrosis by lung ventilation imaging with hyperpolarised gas MRI.
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Development and validation of a clinical risk score to predict mortality after percutaneous coronary intervention.
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Novel blood pressure locus and gene discovery using genome-wide association study and expression data sets from blood and the kidney.
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Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor.
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Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study.
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Supporting Looked After Children and Care Leavers In Decreasing Drugs, and alcohol (SOLID): Protocol for a pilot feasibility randomised controlled trial of interventions to decrease risky substance use (drugs and alcohol) and improve mental health of look.
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Circulating Cell-Free DNA to Guide Prostate Cancer Treatment with PARP Inhibition.
Cancer Discov 2017; 7:1006-17.
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Autologous tolerogenic dendritic cells for rheumatoid and inflammatory arthritis.
Ann Rheum Dis 2017; 76:227-34.
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A randomised controlled trial of losartan as an anti-fibrotic agent in non-alcoholic steatohepatitis.
PLoS ONE 2017; 12:e0175717.
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5-year patient-reported outcomes of bowel and urinary bother in the CHHiP trial (CRUK/06/016).
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Associations of vitamin D status with dietary intakes and physical activity levels among adults from seven European countries: The Food4Me study.
Eur J Nutr 2017; 57:1357-68.
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