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Isabella Harumi Yonehara Noma
,
Larissa Anastacio da Costa Carvalho
,
Denisse Esther Mallaupoma Camarena
,
Renaira Oliveira Silva
,
Manoel Oliveira de Moraes Junior
,
Sophia Tavares de Souza
,
Julia Newton-Bishop
,
Jérémie Nsengimana
,
Silvya Stuchi Maria-Engler
(2024).
Peroxiredoxin-2 represses NRAS-mutated melanoma cells invasion by modulating EMT markers
.
Biomedicine & Pharmacotherapy
.
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DOI
URL
Faye Wolstenhulme
,
Irena Bibby
,
Michael Cole
,
Lydia Grixti
,
Naomi McGregor
,
Penny Bradley
,
Rebecca H Maier
,
Jenn Walker
,
Simon H Pearce
,
James Wason
(2024).
Graves-PCD: protocol for a randomised, dose-finding, adaptive trial of the plasma cell-depleting agent daratumumab in severe Graves’ disease
.
BMJ Open
.
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DOI
URL
Karen Schreiber
,
Christine Graversgaard
,
Beverley J Hunt
,
James M S Wason
,
Nathalie Costedoat-Chalumeau
,
Silvia Aguilera
,
Marta M Guerra
,
Jane E Salmon
(2024).
Challenges of designing and conducting cohort studies and clinical trials in populations of pregnant people
.
The Lancet Rheumatology
.
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DOI
URL
Athimalaipet V Ramanan
,
James M S Wason
(2024).
Adaptive and innovative study design in rare diseases
.
Archives of Disease in Childhood
.
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DOI
URL
Andrew J Fisher
,
Michael White
,
Nicola Goudie
,
Anneka Kershaw
,
Julia Phillipson
,
Michelle Bardgett
,
Joanne Lally
,
Alex Bevin-Nicholls
,
Thomas Chadwick
,
Andrew Bryant
,
Sian Russell
,
Hesther Smith
,
Laura Frisby
,
Rebecca Errington
,
Martin Carby
,
Richard Thompson
,
Karthik Santhanakrishnan
,
Jasvir Parmar
,
James L Lordan
,
Luke Vale
,
Helen Hancock
,
Catherine Exley
,
Andrew R Gennery
,
James MS Wason
(2024).
Extracorporeal photopheresis (ECP) in the treatment of chronic lung allograft dysfunction (CLAD): a prospective, multicentre, open-label, randomised controlled trial studying the addition of ECP to standard care in the treatment of bilateral lung transplant patients with CLAD (E-CLAD UK)
.
BMJ Open Respiratory Research
.
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DOI
URL
Karen Yirmiya
,
Matthew Constantinou
,
Elizabeth Simes
,
Anthony Bateman
,
James Wason
,
Jessica Yakeley
,
Mary McMurran
,
Mike Crawford
,
Alison Frater
,
Paul Moran
,
Barbara Barrett
,
Angus Cameron
,
Zoe Hoare
,
Elizabeth Allison
,
Stephen Pilling
,
Stephen Butler
,
Peter Fonagy
(2024).
The mediating role of reflective functioning and general psychopathology in the relationship between childhood conduct disorder and adult aggression among offenders
.
Psychological Medicine
.
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DOI
URL
Leher Gumber
,
Opeyemi Agbeleye
,
Alex Inskip
,
Ross Fairbairn
,
Madeleine Still
,
Luke Ouma
,
Jingky Lozano-kuehne
,
Michelle Bardgett
,
John D Isaacs
,
James MS Wason
,
Dawn Craig
,
Arthur G Pratt
(2024).
Operational complexities in international clinical trials: a systematic review of challenges and proposed solutions
.
BMJ Open
.
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DOI
URL
Lucy Godson
,
Navid Alemi
,
Jérémie Nsengimana
,
Graham P. Cook
,
Emily L. Clarke
,
Darren Treanor
,
D. Timothy Bishop
,
Julia Newton-Bishop
,
Ali Gooya
,
Derek Magee
(2024).
Immune subtyping of melanoma whole slide images using multiple instance learning
.
Medical Image Analysis
.
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DOI
URL
Nicola J Wyatt
,
Hannah Watson
,
Carl A Anderson
,
Nicholas A Kennedy
,
Tim Raine
,
Tariq Ahmad
,
Dean Allerton
,
Michelle Bardgett
,
Emma Clark
,
Dawn Clewes
,
Cristina Cotobal Martin
,
Mary Doona
,
Jennifer A Doyle
,
Katherine Frith
,
Helen C Hancock
,
Ailsa L Hart
,
Victoria Hildreth
,
Peter M Irving
,
Sameena Iqbal
,
Ciara Kennedy
,
Andrew King
,
Sarah Lawrence
,
Charlie W Lees
,
Robert Lees
,
Laura Letchford
,
Trevor Liddle
,
James O Lindsay
,
Rebecca H Maier
,
John C Mansfield
,
Julian R Marchesi
,
Naomi McGregor
,
Rebecca E McIntyre
,
Jasmin Ostermayer
,
Tolulope Osunnuyi
,
Nick Powell
,
Natalie J Prescott
,
Jack Satsangi
,
Shriya Sharma
,
Tara Shrestha
,
Ally Speight
,
Michelle Strickland
,
James MS Wason
,
Kevin Whelan
,
Ruth Wood
,
Gregory R Young
,
Xinyue Zhang
,
Miles Parkes
,
Christopher J Stewart
,
Luke Jostins-Dean
,
Christopher A Lamb
(2024).
Defining predictors of responsiveness to advanced therapies in Crohn’s disease and ulcerative colitis: protocol for the IBD-RESPONSE and nested CD-metaRESPONSE prospective, multicentre, observational cohort study in precision medicine
.
BMJ Open
.
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DOI
URL
William King
,
Tara Homer
,
Chris Harding
,
Helen Mossop
,
Thomas Chadwick
,
Alaa Abouhajar
,
Luke Vale
(2024).
Cost-effectiveness of methenamine hippurate compared with antibiotic prophylaxis for the management of recurrent urinary tract infections in secondary care: a multicentre, open-label, randomised, non-inferiority trial
.
BMJ Open
.
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DOI
URL
Suraiya Dubash
,
Tara D. Barwick
,
Kasia Kozlowski
,
Andrea G. Rockall
,
Sairah Khan
,
Sameer Khan
,
Siraj Yusuf
,
Angela Lamarca
,
Juan W. Valle
,
Richard A. Hubner
,
Mairéad G. McNamara
,
Andrea Frilling
,
Tricia Tan
,
Florian Wernig
,
Jeannie Todd
,
Karim Meeran
,
Bhavesh Pratap
,
Saleem Azeem
,
Michael Huiban
,
Nicholas Keat
,
Jingky P. Lozano-Kuehne
,
Eric O. Aboagye
,
Rohini Sharma
(2024).
Somatostatin Receptor Imaging with [18F]FET-βAG-TOCA PET/CT and [68Ga]Ga-DOTA-Peptide PET/CT in Patients with Neuroendocrine Tumors: A Prospective, Phase 2 Comparative Study
.
Journal of Nuclear Medicine
.
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DOI
URL
Frances Varian
,
Jennifer Dick
,
Christian Battersby
,
Stefan Roman
,
Jenna Ablott
,
Lisa Watson
,
Sarah Binmahfooz
,
Hamza Zafar
,
Gerry Colgan
,
John Cannon
,
Jay Suntharalingam
,
Jim Lordan
,
Luke Howard
,
Colm McCabe
,
John Wort
,
Laura Price
,
Colin Church
,
Neil Hamilton
,
Iain Armstrong
,
Abdul Hameed
,
Judith Hurdman
,
Charlie Elliot
,
Robin Condliffe
,
Martin Wilkins
,
Alastair Webb
,
David Adlam
,
Ray L. Benza
,
Kazem Rahimi
,
Mohadeseh Shojaei‐Shahrokhabadi
,
Nan X. Lin
,
James M. S. Wason
,
Alasdair McIntosh
,
Alex McConnachie
,
Jennifer T. Middleton
,
Roger Thompson
,
David G. Kiely
,
Mark Toshner
,
Alexander Rothman
(2024).
Pulmonary Hypertension: Intensification and Personalization of Combination Rx (PHoenix): A phase IV randomized trial for the evaluation of dose‐response and clinical efficacy of riociguat and selexipag using implanted technologies
.
Pulmonary Circulation
.
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DOI
URL
Shaun Hiu
,
Tingting Yong
,
Jahfer Hasoon
,
M. Dawn Teare
,
John‐Paul Taylor
,
Nan Lin
(2024).
Instrumental variables in real‐world clinical studies of dementia and neurodegenerative disease: Systematic review of the subject‐matter argumentation, falsification test, and study design strategies to justify a valid instrument
.
Brain and Behavior
.
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DOI
URL
Heather Lambert
,
Shaun Hiu
,
Malcolm Coulthard
,
John N S Matthews
,
Ruth Wood
,
Jean Crosier
,
Rachel Agbeko
,
Thomas Brick
,
Heather Duncan
,
David Grant
,
Quen Mok
,
Andrew Gustaf Nyman
,
John Pappachan
,
Paul Wellman
,
Chris Boucher
,
Joe Bulmer
,
Denise Chisholm
,
Kirsten Cromie
,
Victoria Emmet
,
Richard Feltbower
,
Michael Grayling
,
Rebecca Harrison
,
Eva-Maria Holstein
,
Ciara A Kennedy
,
Elaine McColl
,
Kevin Morris
,
Lee Norman
,
Julie Office
,
Roger Parslow
,
Christine Pattinson
,
Shriya Sharma
,
Jonathan Smith
,
Alison Steel
,
Rachel Steel
,
Jayne Straker
,
Lamprini Vrana
,
Jenn Walker
,
Mike Whitaker
,
Jim Wightman
,
Nina Wilson
,
Lucy Wirz
(2024).
Evaluation of efficacy, outcomes and safety of infant haemodialysis and ultrafiltration in clinical use: I-KID a stepped wedge cluster RCT
.
Efficacy and Mechanism Evaluation
.
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DOI
URL
Svetlana Cherlin
,
Theophile Bigirumurame
,
Michael J Grayling
,
Jérémie Nsengimana
,
Luke Ouma
,
Aida Santaolalla
,
Fang Wan
,
S Faye Williamson
,
James MS Wason
(2023).
Utilising high-dimensional data in randomised clinical trials: A review of methods and practice
.
Research Methods in Medicine & Health Sciences
.
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DOI
URL
Janet A Wilson
,
Tony Fouweather
,
Deborah D Stocken
,
Tara Homer
,
Catherine Haighton
,
Nikki Rousseau
,
James O’Hara
,
Luke Vale
,
Rebecca Wilson
,
Sonya Carnell
,
Scott Wilkes
,
Jill Morrison
,
Kim Ah-See
,
Sean Carrie
,
Claire Hopkins
,
Nicola Howe
,
Musheer Hussain
,
Lyndsay Lindley
,
Kenneth MacKenzie
,
Lorraine McSweeney
,
Hisham Mehanna
,
Christopher Raine
,
Ruby Smith Whelan
,
Frank Sullivan
,
Alexander von Wilamowitz-Moellendorff
,
Dawn Teare
(2023).
Tonsillectomy compared with conservative management in patients over 16 years with recurrent sore throat: the NATTINA RCT and economic evaluation
.
Health Technology Assessment
.
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DOI
URL
Raya Vinogradov
,
Vikki Smith
,
Shaun Hiu
,
Catherine McParlin
,
Allison Farnworth
,
Vera Araújo-Soares
(2023).
Let’s talk aspirin: A survey of barriers and facilitators faced by midwives when engaging in conversations about aspirin with women at risk of pre-eclampsia
.
Midwifery
.
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DOI
URL
Ruth McGovern
,
Deborah Smart
,
Hayley Alderson
,
Tony Fouweather
,
Eileen Kaner
(2023).
Promoting Alcohol Reduction in Non-Treatment Seeking parents (PAReNTS): a pilot feasibility cluster randomized controlled trial of brief alcohol interventions with parents in contact with child safeguarding services
.
Alcohol and Alcoholism
.
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DOI
URL
David S. Robertson
,
James M. S. Wason
,
Aaditya Ramdas
(2023).
Online Multiple Hypothesis Testing
.
Statistical Science
.
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DOI
URL
Martin Law
,
Dominique-Laurent Couturier
,
Babak Choodari-Oskooei
,
Phillip Crout
,
Carrol Gamble
,
Peter Jacko
,
Philip Pallmann
,
Mark Pilling
,
David S. Robertson
,
Michael Robling
,
Matthew R. Sydes
,
Sofía S. Villar
,
James Wason
,
Graham Wheeler
,
S. Faye Williamson
,
Christina Yap
,
Thomas Jaki
(2023).
Medicines and Healthcare products Regulatory Agency’s “Consultation on proposals for legislative changes for clinical trials”: a response from the Trials Methodology Research Partnership Adaptive Designs Working Group, with a focus on data sharing
.
Trials
.
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DOI
URL
Sean Carrie
,
James O’Hara
,
Tony Fouweather
,
Tara Homer
,
Nikki Rousseau
,
Leila Rooshenas
,
Alison Bray
,
Deborah D Stocken
,
Laura Ternent
,
Katherine Rennie
,
Emma Clark
,
Nichola Waugh
,
Alison J Steel
,
Jemima Dooley
,
Michael Drinnan
,
David Hamilton
,
Kelly Lloyd
,
Yemi Oluboyede
,
Caroline Wilson
,
Quentin Gardiner
,
Naveed Kara
,
Sadie Khwaja
,
Samuel C Leong
,
Sangeeta Maini
,
Jillian Morrison
,
Paul Nix
,
Janet A Wilson
,
M Dawn Teare
(2023).
Clinical effectiveness of septoplasty versus medical management for nasal airways obstruction: multicentre, open label, randomised controlled trial
.
BMJ
.
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DOI
URL
Vicky Brocklebank
,
Patrick R. Walsh
,
Kate Smith-Jackson
,
Thomas M. Hallam
,
Kevin J. Marchbank
,
Valerie Wilson
,
Theophile Bigirumurame
,
Tina Dutt
,
Emma K. Montgomery
,
Michal Malina
,
Edwin K. S. Wong
,
Sally Johnson
,
Neil S. Sheerin
,
David Kavanagh
(2023).
Atypical hemolytic uremic syndrome in the era of terminal complement inhibition: an observational cohort study
.
Blood
.
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DOI
URL
Lindsay Pennington
,
Stuart Cunningham
,
Shaun Hiu
,
Ghada Khattab
,
Vicky Ryan
(2023).
The impact of the Speech Systems Approach on intelligibility for children with cerebral palsy: a secondary analysis
.
Efficacy and Mechanism Evaluation
.
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DOI
URL
Marjan Nouri-Keshtkar
,
Mohadeseh Shojaei Shahrokhabadi
,
Azadeh Ghaheri
,
Roya Hosseini
,
Hassan Ketabi
,
Mojtaba Farjam
,
Ding-Geng Chen
,
Mehdi Rezaeian
,
Reza Homayounfar
,
Yaser Tahamtani
,
Mehdi Totonchi
(2023).
Role of gender in explaining metabolic syndrome risk factors in an Iranian rural population using structural equation modelling
.
Scientific Reports
.
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DOI
URL
James M. S. Wason
,
Oliver Bandmann
(2023).
The potential of innovative trial design for efficiently evaluating repurposed drugs
.
Nature Reviews Drug Discovery
.
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DOI
URL
Mohita Tagore
,
Emiliano Hergenreder
,
Sarah C. Perlee
,
Nelly M. Cruz
,
Laura Menocal
,
Shruthy Suresh
,
Eric Chan
,
Maayan Baron
,
Stephanie Melendez
,
Asim Dave
,
Walid K. Chatila
,
Jérémie Nsengimana
,
Richard P. Koche
,
Travis J. Hollmann
,
Trey Ideker
,
Lorenz Studer
,
Andrea Schietinger
,
Richard M. White
(2023).
GABA Regulates Electrical Activity and Tumor Initiation in Melanoma
.
Cancer Discovery
.
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DOI
URL
Miranda Morton
,
Nina Wilson
,
Tara Marie Homer
,
Laura Simms
,
Alison Steel
,
Rebecca Maier
,
James Wason
,
Laura Ternent
,
Alaa Abouhajar
,
Maria Allen
,
Richard Joyce
,
Victoria Hildreth
,
Rachel Lakey
,
Svetlana Cherlin
,
Adam Walker
,
Graham Devereux
,
James D Chalmers
,
Adam T Hill
,
Charles Haworth
,
John R Hurst
,
Anthony De Soyza
(2023).
Dual bronchodilators in Bronchiectasis study (DIBS): protocol for a pragmatic, multicentre, placebo-controlled, three-arm, double-blinded, randomised controlled trial studying bronchodilators in preventing exacerbations of bronchiectasis
.
BMJ Open
.
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DOI
URL
Ruqayya A. Azher
,
James M. S. Wason
,
Michael J. Grayling
(2023).
A Comparison of Randomization Methods for Multi-Arm Clinical Trials
.
Statistics in Biopharmaceutical Research
.
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DOI
URL
Paula Cunnea
,
Edward W. Curry
,
Elizabeth L. Christie
,
Katherine Nixon
,
Chun Hei Kwok
,
Ahwan Pandey
,
Ratri Wulandari
,
Kerstin Thol
,
Jennifer Ploski
,
Cristina Morera-Albert
,
Stephen McQuaid
,
Jingky Lozano-kuehne
,
James J. Clark
,
Jonathan Krell
,
Euan A. Stronach
,
Iain A. McNeish
,
David D.L. Bowtell
,
Christina Fotopoulou
(2023).
Spatial and temporal intra-tumoral heterogeneity in advanced HGSOC: Implications for surgical and clinical outcomes
.
Cell Reports Medicine
.
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DOI
URL
Mark Lythgoe
,
Paola Dama
,
Adam Enver Frampton
,
Emily Pickford
,
Laura Tookman
,
Paula Cunnea
,
Christina Fotopoulou
,
Daniel Liu
,
James Clark
,
Jingky Lozano-kuehne
,
Philip David Badman
,
Aaron Clarke
,
Sasha Chetal
,
Gayle Fyvie
,
Alex Stevenson
,
Jonathan Krell
(2023).
Immune modulation and the oral live biotherapeutic product, MRx0518, in treatment-naïve patients with cancer: Updated safety data.
.
Journal of Clinical Oncology
.
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DOI
URL
Theophile Bigirumurame
,
Shaun Kuan Wei Hiu
,
M Dawn Teare
,
James M S Wason
,
Andrew Bryant
,
Matthew Breckons
(2023).
Current practices in studies applying the target trial emulation framework: a protocol for a systematic review
.
BMJ Open
.
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DOI
URL
Janet A Wilson
,
James O’Hara
,
Tony Fouweather
,
Tara Homer
,
Deborah D Stocken
,
Luke Vale
,
Catherine Haighton
,
Nikki Rousseau
,
Rebecca Wilson
,
Lorraine McSweeney
,
Scott Wilkes
,
Jill Morrison
,
Kenneth MacKenzie
,
Kim Ah-See
,
Sean Carrie
,
Claire Hopkins
,
Nicola Howe
,
Musheer Hussain
,
Hisham Mehanna
,
Christopher Raine
,
Frank Sullivan
,
Alexander von Wilamowitz-Moellendorff
,
M Dawn Teare
(2023).
Conservative management versus tonsillectomy in adults with recurrent acute tonsillitis in the UK (NATTINA): a multicentre, open-label, randomised controlled trial
.
The Lancet
.
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DOI
URL
Lou E. Whitehead
,
Oliver Sailer
,
Miles D. Witham
,
James M. S. Wason
(2023).
Bayesian borrowing for basket trials with longitudinal outcomes
.
Statistics in Medicine
.
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DOI
URL
Heather Lambert
,
Shaun Hiu
,
Malcolm G. Coulthard
,
John N. S. Matthews
,
Eva-Maria Holstein
,
Jean Crosier
,
Rachel Agbeko
,
Thomas Brick
,
Heather Duncan
,
David Grant
,
Quen Mok
,
Andrew Gustaf Nyman
,
John Pappachan
,
Chris Boucher
,
Joe Bulmer
,
Denise Chisholm
,
Kirsten Cromie
,
Victoria Emmet
,
Richard G. Feltbower
,
Arunoday Ghose
,
Michael Grayling
,
Rebecca Harrison
,
Ciara A. Kennedy
,
Elaine McColl
,
Kevin Morris
,
Lee Norman
,
Julie Office
,
Roger Parslow
,
Christine Pattinson
,
Shriya Sharma
,
Jonathan Smith
,
Alison Steel
,
Rachel Steel
,
Jayne Straker
,
Lamprini Vrana
,
Jenn Walker
,
Paul Wellman
,
Mike Whitaker
,
Jim Wightman
,
Nina Wilson
,
Lucy Wirz
,
Ruth Wood
(2023).
The Infant KIdney Dialysis and Utrafiltration (I-KID) Study: A Stepped-Wedge Cluster-Randomized Study in Infants, Comparing Peritoneal Dialysis, Continuous Venovenous Hemofiltration, and Newcastle Infant Dialysis Ultrafiltration System, a Novel Infant Hemodialysis Device
.
Pediatric Critical Care Medicine
.
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DOI
URL
Barry Wright
,
Ellen Kingsley
,
Cindy Cooper
,
Katie Biggs
,
Matthew Bursnall
,
Han-I Wang
,
Tim Chater
,
Elizabeth Coates
,
M Dawn Teare
,
Kirsty McKendrick
,
Gina Gomez de la Cuesta
,
Amy Barr
,
Kiera Solaiman
,
Anna Packham
,
David Marshall
,
Danielle Varley
,
Roshanak Nekooi
,
Steve Parrott
,
Shehzad Ali
,
Simon Gilbody
,
Ann Le Couteur
(2023).
I-SOCIALISE: Results from a cluster randomised controlled trial investigating the social competence and isolation of children with autism taking part in LEGO® based therapy (‘Play Brick Therapy’) clubs in school environments
.
Autism
.
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DOI
URL
Mark E. McClure
,
Seerapani Gopaluni
,
James Wason
,
Robert B. Henderson
,
Andre Van Maurik
,
Caroline C.O. Savage
,
Charles D. Pusey
,
Alan D. Salama
,
Paul A. Lyons
,
Jacinta Lee
,
Kim Mynard
,
David R. Jayne
,
Rachel B. Jones
(2023).
A randomised study of rituximab and belimumab sequential therapy in PR3 ANCA-associated vasculitis (COMBIVAS): design of the study protocol
.
Trials
.
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DOI
URL
Henry David Jeffry Hogg
,
Katie Brittain
,
Dawn Teare
,
James Talks
,
Konstantinos Balaskas
,
Pearse Keane
,
Gregory Maniatopoulos
(2023).
Safety and efficacy of an artificial intelligence-enabled decision tool for treatment decisions in neovascular age-related macular degeneration and an exploration of clinical pathway integration and implementation: protocol for a multi-methods validation study
.
BMJ Open
.
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DOI
URL
Toshi A Furukawa
,
Aran Tajika
,
Masatsugu Sakata
,
Yan Luo
,
Rie Toyomoto
,
Masaru Horikoshi
,
Tatsuo Akechi
,
Norito Kawakami
,
Takeo Nakayama
,
Naoki Kondo
,
Shingo Fukuma
,
Hisashi Noma
,
Helen Christensen
,
Ronald C Kessler
,
Pim Cuijpers
,
James M S Wason
(2023).
Four 2×2 factorial trials of smartphone CBT to reduce subthreshold depression and to prevent new depressive episodes among adults in the community–RESiLIENT trial (Resilience Enhancement with Smartphone in LIving ENvironmenTs): a master protocol
.
BMJ Open
.
Cite
DOI
URL
Nuredin I. Mohammed
,
James Wason
,
Thomas Mendy
,
Stefan A. Nass
,
Ogochukwu Ofordile
,
Famalang Camara
,
Bakary Baldeh
,
Chilel Sanyang
,
Amadou T. Jallow
,
Ilias Hossain
,
Nuno Faria
,
Jonathan J. Powell
,
Andrew M. Prentice
,
Dora I.A. Pereira
(2023).
A novel nano-iron supplement versus standard treatment for iron deficiency anaemia in children 6–35 months (IHAT-GUT trial): a double-blind, randomised, placebo-controlled non-inferiority phase II trial in The Gambia
.
eClinicalMedicine
.
Cite
DOI
URL
David Winston Hamilton
,
James O’Hara
,
Amarkumar Rajgor
,
Gerald Selby
,
Mhairi Anderson
,
Kim Keltie
,
Rosalyn Parker
,
Dawn Teare
,
Joanne Patterson
,
Terry M Jones
,
Linda Sharp
(2023).
Precision medicine in laryngeal cancer: protocol of the laryngeal cancer cohort (LARCH)
.
BMJ Open
.
Cite
DOI
URL
Reza Faryabi
,
Tahereh Rahimi
,
Salman Daneshi
,
Ehsan Movahed
,
Ali Reza Yusefi
,
Mohadeseh Shojaei Shahrokhabadi
,
Ding-Geng (Din) Chen
,
Saeedeh Azaraeen
,
Cain C. T. Clark
(2022).
Stress Coping Styles in Family and Relatives of Coronavirus Disease 2019 (COVID-19) Patients in the South of Iran: Application of Lazarus and Folkman’s Theory of Stress Coping
.
The Open Public Health Journal
.
Cite
DOI
URL
Andrew Bryant
,
Eugenie Johnson
,
Michael Grayling
,
Shaun Hiu
,
Ahmed Elattar
,
Ketankumar Gajjar
,
Dawn Craig
,
Luke Vale
,
Raj Naik
(2022).
Residual Disease Threshold After Primary Surgical Treatment for Advanced Epithelial Ovarian Cancer, Part 1: A Systematic Review and Network Meta-Analysis
.
American Journal of Therapeutics
.
Cite
DOI
URL
Michael Nugent
,
Valerie Bryant
,
Chrissie Butcher
,
Holly Fisher
,
Sean Gill
,
Rebecca Goranova
,
Shaun Hiu
,
Lyndsay Lindley
,
James O’Hara
,
Yemi Oluboyede
,
Joanne Patterson
,
Tim Rapley
,
Tomos Robinson
,
Nikki Rousseau
,
Vicky Ryan
,
Ramkumar Shanmugasundaram
,
Linda Sharp
,
Ruby Smith Whelan
,
Deborah D Stocken
,
Laura Ternent
,
Janet Wilson
,
Jenn Walker
(2022).
Photobiomodulation in the management of oral mucositis for adult head and neck cancer patients receiving irradiation: the LiTEFORM RCT
.
Health Technology Assessment
.
Cite
DOI
URL
Michael J Grayling
,
James MS Wason
(2022).
Point estimation following a two-stage group sequential trial
.
Statistical Methods in Medical Research
.
Cite
DOI
URL
ANN R. WEBB
,
BIANCA M. I. VAN DER ZANDE
,
RICHARD C. KIFT
,
HELEN O'NEIL
,
Nan Xuan Lin
,
DAVID WRIGHT
(2022).
Ultra-low Ultraviolet Radiation in Office Lighting Can Moderate Seasonal Vitamin D Cycle: A Pilot Study
.
Anticancer Research
.
Cite
DOI
URL
S. Faye Williamson
,
Michael J. Grayling
,
Adrian P. Mander
,
Nurulamin M. Noor
,
Joshua S. Savage
,
Christina Yap
,
James M. S. Wason
(2022).
Subgroup analyses in randomized controlled trials frequently categorized continuous subgroup information
.
Journal of Clinical Epidemiology
.
Cite
DOI
URL
Adam J. Streeter
,
Lauren R. Rodgers
,
Jane Masoli
,
Nan X. Lin
,
Alessandro Blé
,
Willie Hamilton
,
William E. Henley
(2022).
Real-world effectiveness of pneumococcal vaccination in older adults: Cohort study using the UK Clinical Practice Research Datalink
.
PLOS ONE
.
Cite
DOI
URL
Barry Wright
,
Lucy Tindall
,
Alexander J Scott
,
Ellen Lee
,
Katie Biggs
,
Cindy Cooper
,
Penny Bee
,
Han-I Wang
,
Lina Gega
,
Emily Hayward
,
Kiera Solaiman
,
M Dawn Teare
,
Thompson Davis
,
Karina Lovell
,
Jon Wilson
,
Dean McMillan
,
Amy Barr
,
Hannah Edwards
,
Jennifer Lomas
,
Chris Turtle
,
Steve Parrott
,
Catarina Teige
,
Tim Chater
,
Rebecca Hargate
,
Shehzad Ali
,
Sarah Parkinson
,
Simon Gilbody
,
David Marshall
(2022).
One-session treatment compared with multisession CBT in children aged 7–16 years with specific phobias: the ASPECT non-inferiority RCT
.
Health Technology Assessment
.
Cite
DOI
URL
Luke O. Ouma
,
James M. S. Wason
,
Haiyan Zheng
,
Nina Wilson
,
Michael Grayling
(2022).
Design and analysis of umbrella trials: Where do we stand?
.
Frontiers in Medicine
.
Cite
DOI
URL
Luke O. Ouma
,
Michael J. Grayling
,
James M. S. Wason
,
Haiyan Zheng
(2022).
Bayesian modelling strategies for borrowing of information in randomised basket trials
.
Journal of the Royal Statistical Society: Series C (Applied Statistics)
.
Cite
DOI
URL
C. Fiorella Murillo Perez
,
Holly Fisher
,
Shaun Hiu
,
Dorcas Kareithi
,
Femi Adekunle
,
Tracy Mayne
,
Elizabeth Malecha
,
Erik Ness
,
Adriaan J. van der Meer
,
Willem J. Lammers
,
Palak J. Trivedi
,
Pier Maria Battezzati
,
Frederik Nevens
,
Kris V. Kowdley
,
Tony Bruns
,
Nora Cazzagon
,
Annarosa Floreani
,
Andrew L. Mason
,
Albert Parés
,
Maria-Carlota Londoño
,
Pietro Invernizzi
,
Marco Carbone
,
Ana Lleo
,
Marlyn J. Mayo
,
George N. Dalekos
,
Nikolaos K. Gatselis
,
Xavier Verhelst
,
Aliya Gulamhusein
,
Harry L. A. Janssen
,
Rachel Smith
,
Steve Flack
,
Victoria Mulcahy
,
Michael Trauner
,
Christopher L. Bowlus
,
Keith D. Lindor
,
Christophe Corpechot
,
Gideon M. Hirschfield
,
James Wason
,
Bettina E. Hansen
,
Richard Sturgess
,
Christopher Healey
,
Anton Gunasekera
,
Yiannis Kallis
,
Gavin Wright
,
Thiriloganathan Mathialahan
,
Richard Evans
,
Jaber Gasem
,
David Ramanaden
,
Emma Ward
,
Mahesh Bhalme
,
Paul Southern
,
James Maggs
,
Mohamed Yousif
,
George Mells
,
Brijesh Srivastava
,
Matthew Foxton
,
Carole Collins
,
Yash Prasad
,
Francisco Porras-Perez
,
Tom Yapp
,
Minesh Patel
,
Roland Ede
,
Martyn Carte
,
Konrad Koss
,
Prayman Sattianayagam
,
Charles Grimley
,
Jude Tidbury
,
Dina Mansour
,
Matilda Beckley
,
Coral Hollywood
,
John Ramag
,
Harriet Gordon
,
Joanne Ridpath
,
Bob Grover
,
George Abouda
,
Ian Rees
,
Mark Narain
,
Imroz Salam
,
Paul Banim
,
Debasish Das
,
Helen Matthews
,
Faiyaz Mohammed
,
Rebecca Jones
,
Sambit Sen
,
George Bird
,
Martin Prince
,
Geeta Prasad
,
Paul Kitchen
,
John Hutchinson
,
Prakash Gupta
,
David Jones
,
Amir Shah
,
Subrata Saha
,
Katharine Pollock
,
Stephen Barclay
,
Natasha McDonald
,
Simon Rushbrook
,
Robert Przemioslo
,
Andrew Millar
,
Steven Mitchell
,
Andrew Davis
,
Asifabbas Naqvi
,
Tom Lee
,
Stephen Ryder
,
Jane Collier
,
Matthew Cramp
,
Richard Aspinal
,
Jonathan Booth
,
Earl Williams
,
Hyder Hussaini
,
John Christie
,
Tehreem Chaudhry
,
Douglas Thorburn
,
Stephen Mann
,
Aftab Ala
,
Julia Maltby
,
Chris Corbett
,
Saket Singhal
,
Barbara Hoeroldt
,
Jeff Butterworth
,
Andrew Douglas
,
Rohit Sinha
,
Simon Panter
,
Jeremy Shearman
,
Gary Bray
,
Michael Roberts
,
Daniel Forton
,
Nicola Taylor
,
Wisam Jafar
,
Matthew Cowan
,
Chin Lye Ch′ng
,
Mesbah Rahman
,
Emma Wesley
,
Sanjiv Jain
,
Aditya Mandal
,
Mark Wright
,
Palak Trivedi
,
Fiona Gordon
,
Esther Unitt
,
Andrew Austin
,
Altaf Palegwala
,
Vishwaraj Vemala
,
Andrew Higham
,
Jocelyn Fraser
,
Andy Li
,
Subramaniam Ramakrishnan
,
Alistair King
,
Simon Whalley
,
Ian Gee
,
Richard Keld
,
Helen Fellows
,
James Gotto
,
Charles Millson
(2022).
Greater Transplant-Free Survival in Patients Receiving Obeticholic Acid for Primary Biliary Cholangitis in a Clinical Trial Setting Compared to Real-World External Controls
.
Gastroenterology
.
Cite
DOI
URL
Alaa Abouhajar
,
Lisa Alcock
,
Theophile Bigirumurame
,
Penny Bradley
,
Laura Brown
,
Ian Campbell
,
Silvia Del Din
,
Julie Faitg
,
Gavin Falkous
,
Gráinne S. Gorman
,
Rachel Lakey
,
Robert McFarland
,
Jane Newman
,
Lynn Rochester
,
Vicky Ryan
,
Hesther Smith
,
Alison Steel
,
Renae J. Stefanetti
,
Huizhong Su
,
Robert W. Taylor
,
Naomi J. P. Thomas
,
Helen Tuppen
,
Amy E. Vincent
,
Charlotte Warren
,
Gillian Watson
(2022).
Acipimox in Mitochondrial Myopathy (AIMM): study protocol for a randomised, double-blinded, placebo-controlled, adaptive design trial of the efficacy of acipimox in adult patients with mitochondrial myopathy
.
Trials
.
Cite
DOI
URL
Samuel K Sarkodie
,
James MS Wason
,
Michael J Grayling
(2022).
A hybrid approach to comparing parallel-group and stepped-wedge cluster-randomized trials with a continuous primary outcome when there is uncertainty in the intra-cluster correlation
.
Clinical Trials
.
Cite
DOI
URL
Andrew Bryant
,
Michael Grayling
,
Ahmed Elattar
,
Ketankumar Gajjar
,
Dawn Craig
,
Luke Vale
,
Raj Naik
(2022).
Residual Disease After Primary Surgical Treatment for Advanced Epithelial Ovarian Cancer: Network Meta-analysis Incorporating Expert Elicitation to Adjust for Publication Bias
.
American Journal of Therapeutics
.
Cite
DOI
URL
James M. S. Wason
,
Munyaradzi Dimairo
,
Katie Biggs
,
Sarah Bowden
,
Julia Brown
,
Laura Flight
,
Jamie Hall
,
Thomas Jaki
,
Rachel Lowe
,
Philip Pallmann
,
Mark A. Pilling
,
Claire Snowdon
,
Matthew R. Sydes
,
Sofía S. Villar
,
Christopher J. Weir
,
Nina Wilson
,
Christina Yap
,
Helen Hancock
,
Rebecca Maier
(2022).
Practical guidance for planning resources required to support publicly-funded adaptive clinical trials
.
BMC Medicine
.
Cite
DOI
URL
Barry Wright
,
Lucy Tindall
,
Alexander J. Scott
,
Ellen Lee
,
Cindy Cooper
,
Katie Biggs
,
Penny Bee
,
Han-I Wang
,
Lina Gega
,
Emily Hayward
,
Kiera Solaiman
,
M. Dawn Teare
,
Thompson Davis
,
Jon Wilson
,
Karina Lovell
,
Dean McMillan
,
Amy Barr
,
Hannah Edwards
,
Jennifer Lomas
,
Chris Turtle
,
Steve Parrott
,
Catarina Teige
,
Tim Chater
,
Rebecca Hargate
,
Shezhad Ali
,
Sarah Parkinson
,
Simon Gilbody
,
David Marshall
(2022).
One session treatment (OST) is equivalent to multi-session cognitive behavioral therapy (CBT) in children with specific phobias (ASPECT): results from a national non-inferiority randomized controlled trial
.
Journal of Child Psychology and Psychiatry
.
Cite
DOI
URL
Shaun Kuan Wei Hiu
,
Theophile Bigirumurame
,
Patience Kunonga
,
Andrew Bryant
,
Manjunadh Pillai
(2022).
Neuropsychiatric Inventory domains cluster into neuropsychiatric syndromes in Alzheimer′s disease: A systematic review and meta-analysis
.
Brain and Behavior
.
Cite
DOI
URL
Han-I. Wang
,
Barry Wright
,
Lucy Tindall
,
Cindy Cooper
,
Katie Biggs
,
Ellen Lee
,
M. Dawn Teare
,
Lina Gega
,
Alexander J. Scott
,
Emily Hayward
,
Kiera Solaiman
,
Thompson Davis
,
Dean McMillan
,
Simon Gilbody
,
Steve Parrott
(2022).
Cost and effectiveness of one session treatment (OST) for children and young people with specific phobias compared to multi-session cognitive behavioural therapy (CBT): results from a randomised controlled trial
.
BMC Psychiatry
.
Cite
DOI
URL
Haiyan Zheng
,
Michael J Grayling
,
Pavel Mozgunov
,
Thomas Jaki
,
James M S Wason
(2022).
Bayesian sample size determination in basket trials borrowing information between subsets
.
Biostatistics
.
Cite
DOI
URL
Haiyan Zheng
,
Michael J Grayling
,
Pavel Mozgunov
,
Thomas Jaki
,
James M S Wason
(2022).
Bayesian sample size determination in basket trials borrowing information between subsets
.
Biostatistics
.
Cite
DOI
URL
Katherine J Rennie
,
Miles Witham
,
Penny Bradley
,
Andrew Clegg
,
Stephen Connolly
,
Helen C Hancock
,
Shaun Hiu
,
Leanne Marsay
,
Claire McDonald
,
Laura Robertson
,
Laura Simms
,
Alison J Steel
,
Claire J Steves
,
Bryony Storey
,
James Wason
,
Nina Wilson
,
Thomas von Zglinicki
,
Avan A P Sayer
(2022).
MET-PREVENT: metformin to improve physical performance in older people with sarcopenia and physical prefrailty/frailty – protocol for a double-blind, randomised controlled proof-of-concept trial
.
BMJ Open
.
Cite
DOI
URL
Fulvio Zaccagna
,
Mary A. McLean
,
James T. Grist
,
Joshua Kaggie
,
Richard Mair
,
Frank Riemer
,
Ramona Woitek
,
Andrew B. Gill
,
Surrin Deen
,
Charlie J. Daniels
,
Stephan Ursprung
,
Rolf F. Schulte
,
Kieren Allinson
,
Anita Chhabra
,
Marie-Christine Laurent
,
Matthew Locke
,
Amy Frary
,
Sarah Hilborne
,
Ilse Patterson
,
Bruno D. Carmo
,
Rhys Slough
,
Ian Wilkinson
,
Bristi Basu
,
James Wason
,
Jonathan H. Gillard
,
Tomasz Matys
,
Colin Watts
,
Stephen J. Price
,
Thomas Santarius
,
Martin J. Graves
,
Sarah Jefferies
,
Kevin M. Brindle
,
Ferdia A. Gallagher
(2022).
Imaging Glioblastoma Metabolism by Using Hyperpolarized [1-$łess$sup$greater$13$łess$/sup$greater$C]Pyruvate Demonstrates Heterogeneity in Lactate Labeling: A Proof of Principle Study
.
Radiology: Imaging Cancer
.
Cite
DOI
URL
Giang Nguyen
,
Louise Hayes
,
Lem Ngongalah
,
Theophile Bigirumurame
,
Laura Gaudet
,
Adefisayo Odeniyi
,
Angela Flynn
,
Lisa Crowe
,
Becky Skidmore
,
Alexandre Simon
,
Vikki Smith
,
Nicola Heslehurst
(2022).
Association between maternal adiposity measures and infant health outcomes: A systematic review and meta-analysis
.
Obesity Reviews
.
Cite
DOI
URL
Laura M. Kenny
,
Fiona J Gilbert
,
Gosala Gopalakrishnan
,
Preetha Aravind
,
Tara Barwick
,
Neva Patel
,
Duncan ROBERT Hiscock
,
Istvan Boros
,
Steven Kealey
,
Franklin I Aigbirhio
,
Jingky Lozano-kuehne
,
Susan Jane Cleator
,
Ben Fleming
,
Pippa Riddle
,
Rizvana Ahmad
,
Sue Chua
,
Stephen R. D. Johnston
,
Janine Mansi
,
Gary J. Cook
,
Eric O. Aboagye
(2022).
The HERPET study: Imaging HER2 expression in breast cancer with the novel PET tracer [$łess$sup$greater$18$łess$/sup$greater$F]GE-226, a first-in-patient study.
.
Journal of Clinical Oncology
.
Cite
DOI
URL
María Victoria Castro
,
Gastón Alexis Barbero
,
Paula Máscolo
,
María Belén Villanueva
,
Jérémie Nsengimana
,
Julia Newton-Bishop
,
Edith Illescas
,
María Josefina Quezada
,
Pablo Lopez-Bergami
(2022).
ROR2 promotes epithelial-mesenchymal transition by hyperactivating ERK in melanoma
.
Journal of Cell Communication and Signaling
.
Cite
DOI
URL
R. C. Coombes
,
P. D. Badman
,
J. P. Lozano-Kuehne
,
X. Liu
,
I. R. Macpherson
,
I. Zubairi
,
R. D. Baird
,
N. Rosenfeld
,
J. Garcia-Corbacho
,
N. Cresti
,
R. Plummer
,
A. Armstrong
,
R. Allerton
,
D. Landers
,
H. Nicholas
,
L. McLellan
,
A. Lim
,
F. Mouliere
,
O. E. Pardo
,
M. J. Seckl
(2022).
Results of the phase IIa RADICAL trial of the FGFR inhibitor AZD4547 in endocrine resistant breast cancer
.
Nature Communications
.
Cite
DOI
URL
Chiara Grasso
,
Maja Popovic
,
Elena Isaevska
,
Fulvio Lazzarato
,
Valentina Fiano
,
Daniela Zugna
,
John Pluta
,
Benita Weathers
,
Kurt D′Andrea
,
Kristian Almstrup
,
Lynn Anson-Cartwright
,
D. Timothy. Bishop
,
Stephen J. Chanock
,
Chu Chen
,
Victoria K. Cortessis
,
Marlene D. Dalgaard
,
Siamak Daneshmand
,
Alberto Ferlin
,
Carlo Foresta
,
Megan N. Frone
,
Marija Gamulin
,
Jourik A. Gietema
,
Mark H. Greene
,
Tom Grotmol
,
Robert J. Hamilton
,
Trine B. Haugen
,
Russ Hauser
,
Robert Karlsson
,
Lambertus A. Kiemeney
,
Davor Lessel
,
Patrizia Lista
,
Ragnhild A. Lothe
,
Chey Loveday
,
Coby Meijer
,
Kevin T. Nead
,
Jérémie Nsengimana
,
Rolf I. Skotheim
,
Clare Turnbull
,
David J. Vaughn
,
Fredrik Wiklund
,
Tongzhang Zheng
,
Andrea Zitella
,
Stephen M. Schwartz
,
Katherine A. McGlynn
,
Peter A. Kanetsky
,
Katherine L. Nathanson
,
Lorenzo Richiardi
(2022).
Association study between polymorphisms in DNA methylation-related genes and testicular germ cell tumor risk
.
Cancer Epidemiology, Biomarkers &$mathsemicolon$ Prevention
.
Cite
DOI
URL
Tracey Bywater
,
Vashti Berry
,
Sarah Blower
,
Matthew Bursnall
,
Edward Cox
,
Amanda Mason-Jones
,
Sinéad McGilloway
,
Kirsty McKendrick
,
Siobhan Mitchell
,
Kate Pickett
,
Gerry Richardson
,
Kiera Solaiman
,
M Dawn Teare
,
Simon Walker
,
Karen Whittaker
(2022).
A proportionate, universal parenting programme to enhance social-emotional well-being in infants and toddlers in England: the E-SEE Steps RCT
.
Public Health Research
.
Cite
DOI
URL
Preetha Aravind
,
Sanjay Popat
,
Tara D. Barwick
,
Neil Soneji
,
Mark Lythgoe
,
Jingky Lozano-kuehne
,
Katherina Bernadette Sreter
,
Mattias Bergqvist
,
Neva H. Patel
,
Eric O. Aboagye
,
Laura M. Kenny
(2022).
[$łess$sup$greater$18$łess$/sup$greater$F]Fluorothymidine(FLT)-PET imaging of thymidine kinase 1 pharmacodynamics in non-small cell lung cancer treated with pemetrexed.
.
Journal of Clinical Oncology
.
Cite
DOI
URL
Aritra Mukherjee
,
James M. S. Wason
,
Michael J. Grayling
(2022).
When is a two-stage single-arm trial efficient? An evaluation of the impact of outcome delay
.
European Journal of Cancer
.
Cite
DOI
URL
Chris Harding
,
Thomas Chadwick
,
Tara Homer
,
Jan Lecouturier
,
Helen Mossop
,
Sonya Carnell
,
Will King
,
Alaa Abouhajar
,
Luke Vale
,
Gillian Watson
,
Rebecca Forbes
,
Stephanie Currer
,
Robert Pickard
,
Ian Eardley
,
Ian Pearce
,
Nikesh Thiruchelvam
,
Karen Guerrero
,
Katherine Walton
,
Zahid Hussain
,
Henry Lazarowicz
,
Ased Ali
(2022).
Methenamine hippurate compared with antibiotic prophylaxis to prevent recurrent urinary tract infections in women: the ALTAR non-inferiority RCT
.
Health Technology Assessment
.
Cite
DOI
URL
Shelley Dua
,
Monica Ruiz-Garcia
,
Simon Bond
,
James Dowey
,
Stephen R. Durham
,
Ian Kimber
,
Clare Mills
,
Graham Roberts
,
Isabel Skypala
,
James Wason
,
Pamela Ewan
,
Robert J. Boyle
,
Andrew Clark
(2022).
Effects of Exercise and Sleep Deprivation on Reaction Severity During Oral Peanut Challenge: A Randomized Controlled Trial
.
The Journal of Allergy and Clinical Immunology: In Practice
.
Cite
DOI
URL
Masatsugu Sakata
,
Rie Toyomoto
,
Kazufumi Yoshida
,
Yan Luo
,
Yukako Nakagami
,
Teruhisa Uwatoko
,
Tomonari Shimamoto
,
Aran Tajika
,
Hidemichi Suga
,
Hiroshi Ito
,
Michihisa Sumi
,
Takashi Muto
,
Masataka Ito
,
Hiroshi Ichikawa
,
Masaya Ikegawa
,
Nao Shiraishi
,
Takafumi Watanabe
,
Ethan Sahker
,
Yusuke Ogawa
,
Steven D Hollon
,
Linda M Collins
,
Edward R Watkins
,
James Wason
,
Hisashi Noma
,
Masaru Horikoshi
,
Taku Iwami
,
Toshi A Furukawa
(2022).
Components of smartphone cognitive-behavioural therapy for subthreshold depression among 1093 university students: a factorial trial
.
Evidence Based Mental Health
.
Cite
DOI
URL
Aritra Mukherjee
,
Michael J. Grayling
,
James M. S. Wason
(2022).
Adaptive Designs: Benefits and Cautions for Neurosurgery Trials
.
World Neurosurgery
.
Cite
DOI
URL
Kevin J. Wilson
,
S. Faye Williamson
,
A. Joy Allen
,
Cameron J. Williams
,
Thomas P. Hellyer
,
B. Clare Lendrem
(2022).
Bayesian sample size determination for diagnostic accuracy studies
.
Statistics in Medicine
.
Cite
DOI
URL
Amanda D Busby
,
James Wason
,
Arthur G Pratt
,
Adam Young
,
John D Isaacs
,
Elena Nikiphorou
(2022).
The role of comorbidities alongside patient and disease characteristics on long-term disease activity in RA using UK inception cohort data
.
Rheumatology
.
Cite
DOI
URL
Vivien Li
,
Baptiste Leurent
,
Frederik Barkhof
,
Marie Braisher
,
Fay Cafferty
,
Olga Ciccarelli
,
Arman Eshaghi
,
Emma Gray
,
Jennifer M. Nicholas
,
Mahesh Parmar
,
Guy Peryer
,
Jenny Robertson
,
Nigel Stallard
,
James Wason
,
Jeremy Chataway
(2022).
Designing Multi-arm Multistage Adaptive Trials for Neuroprotection in Progressive Multiple Sclerosis
.
Neurology
.
Cite
DOI
URL
Carolina Castaneda-Garcia
,
Vivek Iyer
,
Jérémie Nsengimana
,
Adam Trower
,
Alastair Droop
,
Kevin M Brown
,
Jiyeon Choi
,
Tongwu Zhang
,
Mark Harland
,
Julia A Newton-Bishop
,
D Timothy Bishop
,
David J Adams
,
Mark M Iles
,
Carla Daniela Robles-Espinoza
(2022).
Defining novel causal SNPs and linked phenotypes at melanoma-associated loci
.
Human Molecular Genetics
.
Cite
DOI
URL
Guy S. Taylor
,
Andy C. Shaw
,
Kieran Smith
,
James Wason
,
Timothy J. McDonald
,
Richard A. Oram
,
Emma Stevenson
,
James A. M. Shaw
,
Daniel J. West
(2022).
Capturing the real-world benefit of residual $p̆beta$-cell function during clinically important time-periods in established Type 1 diabetes
.
Diabetic Medicine
.
Cite
DOI
URL
Haiyan Zheng
,
Thomas Jaki
,
James M. S. Wason
(2022).
Bayesian sample size determination using commensurate priors to leverage preexperimental data
.
Biometrics
.
Cite
DOI
URL
Chris Harding
,
Helen Mossop
,
Tara Homer
,
Thomas Chadwick
,
William King
,
Sonya Carnell
,
Jan Lecouturier
,
Alaa Abouhajar
,
Luke Vale
,
Gillian Watson
,
Rebecca Forbes
,
Stephanie Currer
,
Robert Pickard
,
Ian Eardley
,
Ian Pearce
,
Nikesh Thiruchelvam
,
Karen Guerrero
,
Katherine Walton
,
Zahid Hussain
,
Henry Lazarowicz
,
Ased Ali
(2022).
Alternative to prophylactic antibiotics for the treatment of recurrent urinary tract infections in women: multicentre, open label, randomised, non-inferiority trial
.
BMJ
.
Cite
DOI
URL
Michael J. Grayling
,
Adrian P. Mander
(2022).
Optimised point estimators for multi-stage single-arm phase II oncology trials
.
Journal of Biopharmaceutical Statistics
.
Cite
DOI
URL
Debora D'Angelo Papaiz
,
Flávia Eichemberger Rius
,
Ana Luísa Pedroso Ayub
,
Clarice S. Origassa
,
Hemant Gujar
,
Diogo de Oliveira Pessoa
,
Eduardo Moraes Reis
,
Jérémie Nsengimana
,
Julia Newton-Bishop
,
Christopher E. Mason
,
Daniel J. Weisenberger
,
Gangning Liang
,
Miriam Galvonas Jasiulionis
(2022).
Genes regulated by DNA methylation are involved in distinct phenotypes during melanoma progression and are prognostic factors for patients
.
Molecular Oncology
.
Cite
DOI
URL
Michael J. Grayling
,
James M. S. Wason
,
Sofía S. Villar
(2022).
Response adaptive intervention allocation in stepped-wedge cluster randomized trials
.
Statistics in Medicine
.
Cite
DOI
URL
Michael J. Grayling
,
Martina McMenamin
,
Robert Chandler
,
Rakesh Heer
,
James M. S. Wason
(2022).
Improving power in PSA response analyses of metastatic castration-resistant prostate cancer trials
.
BMC Cancer
.
Cite
DOI
URL
Marco Egle
,
Saima Hilal
,
Anil M Tuladhar
,
Lukas Pirpamer
,
Steven Bell
,
Edith Hofer
,
Marco Duering
,
James Wason
,
Robin G Morris
,
Martin Dichgans
,
Reinhold Schmidt
,
Daniel J Tozer
,
Thomas R. Barrick
,
Christopher Chen
,
Frank-Erik de Leeuw
,
Hugh S Markus
(2022).
Determining the OPTIMAL DTI analysis method for application in cerebral small vessel disease
.
NeuroImage: Clinical
.
Cite
DOI
URL
Han-I Wang
,
Barry Debenham Wright
,
Matthew Bursnall
,
Cindy Cooper
,
Ellen Kingsley
,
Ann Le Couteur
,
Dawn Teare
,
Katie Biggs
,
Kirsty McKendrick
,
Gina Gomez de la Cuesta
,
Tim Chater
,
Amy Barr
,
Kiera Solaiman
,
Anna Packham
,
David Marshall
,
Danielle Varley
,
Roshanak Nekooi
,
Simon Gilbody
,
Steve Parrott
(2022).
Cost-utility analysis of LEGO based therapy for school children and young people with autism spectrum disorder: results from a randomised controlled trial
.
BMJ Open
.
Cite
DOI
URL
S. Faye Williamson
,
Peter Jacko
,
Thomas Jaki
(2021).
Generalisations of a Bayesian decision-theoretic randomisation procedure and the impact of delayed responses
.
Computational Statistics & Data Analysis
.
Cite
DOI
URL
Amoo OS
,
Adewara F
,
Tijani B
,
Onuigbo TI
,
Ikemefuna AS
,
Oraegbu JI
,
Rizvi T
,
Okwuraiwe AP
,
Onwuamah CK
,
Shaibu JO
,
James AB
,
Ohihoin G
,
Ige F
,
Kareithi DN
,
David NA
,
Karera S
,
Agboola HO
,
Adeniyi AO
,
Obi JC
,
Achanya D
,
Odewale EO
,
Oforomeh O
,
Liboro G
,
Nwogbe OA
,
Ezechi OC
,
Adegbola RA
,
Audu RA
,
Salako BL
(2021).
The use of DIY (do it yourself) sampling and telemonitoring model for COVID-19 qPCR testing scale up
.
PLoS ONE
2021; 16:e0259398.
DOI
Michael J. Grayling
,
Adrian P. Mander
(2021).
Two-Stage Single-Arm Trials Are Rarely Analyzed Effectively or Reported Adequately
.
JCO Precision Oncology
.
Cite
DOI
URL
Stephan Ursprung
,
Helen Mossop
,
Ferdia A. Gallagher
,
Evis Sala
,
Richard Skells
,
Jamal A. N. Sipple
,
Thomas J. Mitchell
,
Anita Chhabra
,
Kate Fife
,
Athena Matakidou
,
Gemma Young
,
Amanda Walker
,
Martin G. Thomas
,
Mireia Crispin Ortuzar
,
Mark Sullivan
,
Andrew Protheroe
,
Grenville Oades
,
Balaji Venugopal
,
Anne Y. Warren
,
John Stone
,
Tim Eisen
,
James Wason
,
Sarah J. Welsh
,
Grant D. Stewart
(2021).
The WIRE study a phase II, multi-arm, multi-centre, non-randomised window-of-opportunity clinical trial platform using a Bayesian adaptive design for proof-of-mechanism of novel treatment strategies in operable renal cell cancer – a study protocol
.
BMC Cancer
.
Cite
DOI
URL
Helen Mossop
,
Michael J. Grayling
,
Ferdia A. Gallagher
,
Sarah J. Welsh
,
Grant D. Stewart
,
James M. S. Wason
(2021).
Advantages of multi-arm non-randomised sequentially allocated cohort designs for Phase II oncology trials
.
British Journal of Cancer
.
Cite
DOI
URL
Heather J Lambert
,
Shriya Sharma
,
John N S Matthews
(2021).
I-KID study protocol: evaluation of efficacy, outcomes and safety of a new infant haemodialysis and ultrafiltration machine in clinical use: a randomised clinical investigation using a cluster stepped-wedge design
.
BMJ Paediatrics Open
.
Cite
DOI
URL
Lindsay Bramwell
,
Jackie Morton
,
Anne-Helen Harding
,
Nan Lin
,
Jane Entwistle
(2021).
Determinants of blood and saliva lead concentrations in adult gardeners on urban agricultural sites
.
Environmental Geochemistry and Health
.
Cite
DOI
URL
Nina Wilson
,
Katie Biggs
,
Sarah Bowden
,
Julia Brown
,
Munyaradzi Dimairo
,
Laura Flight
,
Jamie Hall
,
Anna Hockaday
,
Thomas Jaki
,
Rachel Lowe
,
Caroline Murphy
,
Philip Pallmann
,
Mark A. Pilling
,
Claire Snowdon
,
Matthew R. Sydes
,
Sofía S. Villar
,
Christopher J. Weir
,
Jessica Welburn
,
Christina Yap
,
Rebecca Maier
,
Helen Hancock
,
James M. S. Wason
(2021).
Costs and staffing resource requirements for adaptive clinical trials: quantitative and qualitative results from the Costing Adaptive Trials project
.
BMC Medicine
.
Cite
DOI
URL
Nathaniel R. Campbell
,
Anjali Rao
,
Miranda V. Hunter
,
Magdalena K. Sznurkowska
,
Luzia Briker
,
Maomao Zhang
,
Maayan Baron
,
Silja Heilmann
,
Maxime Deforet
,
Colin Kenny
,
Lorenza P. Ferretti
,
Ting-Hsiang Huang
,
Sarah Perlee
,
Manik Garg
,
Jérémie Nsengimana
,
Massimo Saini
,
Emily Montal
,
Mohita Tagore
,
Julia Newton-Bishop
,
Mark R. Middleton
,
Pippa Corrie
,
David J. Adams
,
Roy Rabbie
,
Nicola Aceto
,
Mitchell P. Levesque
,
Robert A. Cornell
,
Itai Yanai
,
Joao B. Xavier
,
Richard M. White
(2021).
Cooperation between melanoma cell states promotes metastasis through heterotypic cluster formation
.
Developmental Cell
.
Cite
DOI
URL
Tim D Cheetham
,
Michael Cole
,
Mario Abinun
,
Amit Allahabadia
,
Tim Barratt
,
Justin H Davies
,
Paul Dimitri
,
Amanda Drake
,
Zainaba Mohamed
,
Robert D Murray
,
Caroline A Steele
,
Nicola Zammitt
,
Sonya Carnell
,
Jonathan Prichard
,
Gillian Watson
,
Sophie Hambleton
,
John N S Matthews
,
Simon H S Pearce
(2021).
Adjuvant Rituximab—Exploratory Trial in Young People With Graves Disease
.
The Journal of Clinical Endocrinology & Metabolism
.
Cite
DOI
URL
Marco Egle
,
Saima Hilal
,
A M Tuladhar
,
Lukas Pirpamer
,
Edith Hofer
,
Marco Duering
,
James Wason
,
Robin G Morris
,
Martin Dichgans
,
Reinhold Schmidt
,
Daniel Tozer
,
Christopher Chen
,
Frank-Erik de Leeuw
,
Hugh S Markus
(2021).
Prediction of dementia using diffusion tensor MRI measures: the OPTIMAL collaboration
.
Journal of Neurology, Neurosurgery & Psychiatry
.
Cite
DOI
URL
Soemedi R
,
Wilson IJ
,
Bentham J
,
Darlay R
,
Töpf A
,
Zelenika D
,
Cosgrove C
,
Setchfield K
,
Thornborough C
,
Granados-Riveron J
,
Blue GM
,
Breckpot J
,
Hellens S
,
Zwolinkski S
,
Glen E
,
Mamasoula C
,
Rahman TJ
,
Hall D
,
Rauch A
,
Devriendt K
,
Gewillig M
,
O'Sullivan J
,
Winlaw DS
,
Bu'Lock F
,
Brook JD
,
Bhattacharya S
,
Lathrop M
,
Santibanez Koref M
,
Cordell HJ
,
Goodship JA
,
Keavney BD
(2021).
Contribution of global rare copy-number variants to the risk of sporadic congenital heart disease
.
Am J Hum Genet
2012; 91:489-501.
DOI
Foo O
,
Hiu S
,
Teare D
,
Syed AA
,
Razvi S
(2021).
A global country-level analysis of the relationship between obesity and COVID-19 cases and mortality
.
Diabetes Obes Metab
2021; DOI:10.1111/dom.14523.
DOI
Busby AD
,
Wason J
,
Pratt AG
,
Young A
,
Isaacs JD
,
Nikiphorou E
(2021).
Predictors of poor function in RA based on two prospective UK inception cohorts. Do comorbidities matter?
.
Rheumatology
2021; DOI:10.1093/rheumatology/keab598.
DOI
Pluta J
,
Pyle LC
,
Nead KT
,
Wilf R
,
Li M
,
Mitra N
,
Weathers B
,
D’Andrea K
,
Almstrup K
,
Anson-Cartwright L
,
Benitez J
,
Brown CD
,
Chanock S
,
Chen C
,
Cortessis VK
,
Ferlin A
,
Foresta C
,
Gamulin M
,
Gietema JA
,
Grasso C
,
Greene MH
,
Grotmol T
,
Hamilton RJ
,
Haugen TB
,
Hauser R
,
Hildebrandt MAT
,
Johnson ME
,
Karlsson R
,
Kiemeney LA
,
Lessel D
,
Lothe RA
,
Loud JT
,
oveday C
,
Martin-Gimeno P
,
Meijer C
,
Nsengimana J
,
Quinn DI
,
Rafnar T
,
Ramdas S
,
Richiardi L
,
Skotheim RI
,
Stefansson K
,
Turnbull C
,
Vaughn DJ
,
Wiklund F
,
Wu X
,
Yang D
,
Zheng T
,
Wells AD
,
Grant SFA
,
Rajpert-De Meyts E
,
Schwartz SM
,
Bishop DT
,
McGlynn KA
,
Kanetsky PA
,
Nathanson KL
,
The Testicular Cancer Consortium
(2021).
Identification of 22 susceptibility loci associated with testicular germ cell tumors
.
Nat Commun
2021; 12:4487.
DOI
Rayner F
,
Anderson AE
,
Baker KF
,
Buckley CD
,
Dyke B
,
Fenton S
,
Filer A
,
Goodyear CS
,
Hilkens CMU
,
Hiu S
,
Kerrigan S
,
Kurowska-Stolarska M
,
Matthews F
,
McInnes I
,
Ng W-F
,
Pratt AG
,
Prichard J
,
Raza K
,
Siebert S
,
Stocken S
,
Teare MD
,
Young S
,
Isaacs JD
(2021).
BIOlogical Factors that Limit sustAined Remission in rhEumatoid arthritis (the BIO-FLARE study): Protocol for a non-randomised longitudinal cohort study
.
BMC Rheumatol
2021; 5:22.
DOI
Watson N
,
Wilson N
,
Shmarov F
,
Zuliani P
,
Reynolds NJ
,
Weatherhead SC
(2021).
The use of psoriasis biomarkers, including trajectory of clinical response, to predict clearance and remission duration to UVB phototherapy
.
JEADV
2021; DOI:10.1111/jdv.17519.
DOI
Azim L
,
Hindmarch P
,
Browne G
,
Chadwick T
,
Clare E
,
Courtney P
,
Dixon L
,
Duffelen N
,
Fouweather T
,
Geddes JR
,
Goudie N
,
Harvey S
,
Helter T
,
Holstein EM
,
Martin G
,
Mawson P
,
McCaffery J
,
Morriss R
,
Simon J
,
Smith D
,
Stokes PRA
,
Walker J
,
Weetman C
,
Wolstenhulme F
,
Young AH
,
Watson S
,
McAllister-Williams RH
(2021).
Study protocol for a randomised placebo-controlled trial of pramipexole in addition to mood stabilisers for patients with treatment resistant bipolar depression (the PAX-BD study)
.
BMC Psychiatry
2021; 21:334.
DOI
Bi O
,
Anene CA
,
Nsengimana J
,
Shelton M
,
Roberts W
,
Newton-Bishop J
,
Boyne JR
(2021).
SFPQ promotes an oncogenic transcriptomic state in melanoma
.
Oncogene
2021; 40:5192-5203.
DOI
Grayling MJ
,
Bigirumurame T
,
Cherlin S
,
Ouma L
,
Zheng H
,
Wason J
(2021).
Innovative trial approaches in immune-mediated inflammatory diseases: Current use and future potential
.
BMC Rheumatol
2021; 5:21.
DOI
Collins A
,
Lendrem D
,
Wason J
,
Tarn J
,
Howard-Tripp N
,
Bodewes I
,
Versnel MA
,
Gottenberg JE
,
Seror R
,
Mariette X
,
Ng WF
(2021).
Revisiting the JOQUER trial: Stratification of primary Sjögren's syndrome and the clinical and interferon response to hydroxychloroquine
.
Rheumatol Int
2021; 41:1593-1600.
DOI
Cherlin S
,
Wason JMS
(2021).
Developing a predictive signature for two trial endpoints using the cross-validated risk scores method
.
Biostatistics
2021; DOI: 10.1093/biostatistics/kxaa055.
Bryant A
,
Lawrie TA
,
Dowswell T
,
Fordham EJ
,
Mitchell S
,
Hill SR
,
Tham TC
(2021).
Ivermectin for prevention and treatment of COVID-19 infection: A systematic review, meta-analysis, and trial sequential analysis to inform clinical guidelines
.
Am J Ther
2021; 28:e434-60.
DOI
Polubothu S
,
Zecchin D
,
Al-Olabi L
,
Lionarons DA
,
Harland M
,
Horswell S
,
Thomas AC
,
Hunt L
,
Wlodarchak N
,
Aguilera P
,
Brand S
,
Bryant D
,
Carrera C
,
Chen H
,
Elgar G
,
Harwood CA
,
Howell M
,
Larue L
,
Loughlin S
,
MacDonald J
,
Malvehy J
,
Martin Barberan SM
,
Martins da Silva V
,
Molina M
,
Morrogh D
,
Moulding D
,
Nsengimana J
,
Pittman A
,
Puig-Butillé J-A
,
Parmar K
,
Sebire NJ
,
Scherer S
,
Stadnik P
,
Stanier P
,
Tell G
,
Waelchli R
,
Zarrei M
,
Puig S
,
Bataille V
,
Xing Y
,
Healy E
,
Moore GE
,
Di W-L
,
Newton-Bishop J
,
Downward J
,
Kinsler VA
(2021).
Inherited duplications of PPP2R3B predispose to nevi and melanoma via a C21orf91-driven proliferative phenotype
.
Genet Med
2021; DOI:10.1038/s41436-021-01204-y.
DOI
Blower SL
,
Berry VL
,
Bursnall MC
,
Cohen J
,
Gridley N
,
Loban A
,
Mandefield L
,
Mason-Jones AJ
,
McGilloway S
,
McKendrick KL
,
Mitchell SB
,
Pickett KE
,
Richardson GA
,
Teare MD
,
Tracey LC
,
Walker SM
,
Whittaker KA
,
Wright J
,
Bywater TJ
(2021).
Enhancing Social-Emotional outcomes in Early years (E-SEE): Randomized pilot study of incredible years infant and toddler programs
.
J Child Fam Stud
2021; 30:1933-49.
DOI
Grayling MJ
,
Mander AP
(2021).
Accounting for variation in the required sample size in the design of group-sequential trials
.
Contemp Clin Trials
2021; 107:106459.
DOI
Fernandez-Garcia C
,
Ternent L
,
Homer TM
,
Rodgers H
,
Bosomworth H
,
Shaw L
,
Aird L
,
Andole S
,
Cohen D
,
Dawson J
,
Finch T
,
Ford G
,
Francis R
,
Hogg S
,
Hughes N
,
Krebs HI
,
Price C
,
Turner D
,
van Wijck F
,
Wilkes S
,
Wilson N
,
Vale L
(2021).
Economic evaluation of robot-assisted training versus an enhanced upper limb therapy programme or usual care for patients with moderate or severe upper limb functional limitation due to stroke: Results from the RATULS randomised controlled trial
.
BMJ Open
2021; 11:e042081.
DOI
Castellucci LC
,
Almeida L
,
Cherlin S
,
Fakiola M
,
Francis RW
,
Carvalho EM
,
Santos da Hora A
,
do Lago TS
,
Figueiredo AB
,
Cavalcanti CM
,
Alves NS
,
Morais KLP
,
Teixeira-Carvalho A
,
Dutra WO
,
Gollob KJ
,
Cordell HJ
,
Blackwell JM
(2021).
A genome-wide association study identifies SERPINB10, CRLF3, STX7, LAMP3, IFNG-AS1, and KRT80 as risk loci contributing to cutaneous leishmaniasis in Brazil
.
Clin Infect Dis
2021; 72:e515-25.
DOI
Bradley J
,
Rowland MK
,
Matthews JNS
,
Adamson AJ
,
Spence S
(2021).
A comparison of food portion size estimation methods among 11–12 year olds: 3D food models vs an online tool using food portion photos (Intake24)
.
BMC Nutr
2021; 7:10.
DOI
Cameron J. Williams
,
Kevin J. Wilson
,
Nina Wilson
(2021).
A Comparison of Prior Elicitation Aggregation Using the Classical Method and SHELF
.
Journal of the Royal Statistical Society Series A: Statistics in Society
.
Cite
DOI
URL
Kunzmann K
,
Grayling MJ
,
Lee KM
,
Robertson DS
,
Rufibach K
,
Wason JMS
(2021).
A review of Bayesian perspectives on sample size derivation for confirmatory trials
.
Am Stat
2021; DOI:10.1080/00031305.2021.1901782.
Vergis N
,
Phillips R
,
Cornelius V
,
Katsarou A
,
Youngstein T
,
Cook L
,
Willicombe M
,
Pilay C
,
Shturova T
,
Almonte M
,
Charania A
,
Turner R
,
Kon OM
,
Cooke G
,
Thursz M
,
Cherlin S
,
Wason J
,
Milojkovic D
,
Innes AJ
,
Cooper N
(2021).
Multi-arm Trial of Inflammatory Signal Inhibitors (MATIS) for hospitalised patients with mild or moderate COVID-19 pneumonia: A structured summary of a study protocol for a randomised controlled trial
.
Trials
2021; 22:270.
DOI
de Oliveira Pessoaa D
,
Eichemberger Rius F
,
D'Angelo Papaiz D
,
Pedroso Ayub AL
,
Santana Morais A
,
Ferreira de Souza C
,
Ferreira da Paixão V
,
Carlos Setubal J
,
Newton-Bishop J
,
Nsengimana J
,
Azevedo H
,
Moraes Reis E
,
Galvonas Jasiulionis M
(2021).
Transcriptional signatures underlying dynamic phenotypic switching and novel disease biomarkers in a linear cellular model of melanoma progression
.
Neoplasia
2021; 23:439-55.
DOI
Fisher HF
,
Boys RJ
,
Gillespie CS
,
Proctor CJ
,
Golightly A
(2021).
Parameter inference for a stochastic kinetic model of expanded polyglutamine proteins
.
Biometrics
2021; DOI:10.1111/biom.13467.
DOI
Ouma LO
,
Grayling MJ
,
Zheng H
,
Wason J
(2021).
Treatment allocation strategies for umbrella trials in the presence of multiple biomarkers: A comparison of methods
.
Pharm Stat
2021; doi:10.1002/pst.2119.
DOI
Juraleviciute M
,
Nsengimana J
,
Newton-Bishop J
,
Hendriks GJ
,
Slipicevic A
(2021).
MX2 mediates establishment of interferon response profile, regulates XAF1, and can sensitize melanoma cells to targeted therapy
.
Cancer Med
2021; doi:10.1002/cam4.3846.
DOI
Wilson N
,
Howel D
,
Bosomworth H
,
Shaw L
,
Rodgers H
(2021).
Analysing the Action Research Arm Test (ARAT): A cautionary tale from the RATULS trial
.
Int J Rehabil Res
2021; doi:10.1097/MRR.0000000000000466.
DOI
Lee KM
,
Brown LC
,
Jaki T
,
Stallard N
,
Wason J
(2021).
Statistical consideration when adding new arms to ongoing clinical trials: The potentials and the caveats
.
Trials
2021; 22:203.
DOI
Lesseur C
,
Ferreiro-Iglesias A
,
Mckay JD
,
Bossé Y
,
Gaborieau V
,
Landi MT
,
hristiani DC
,
aporaso NC
,
Bojesen SE
,
Amos CI
,
Shete S
,
Liu G
,
Rennert G
,
Albanes D
,
Aldrich MC
,
Tardon A
,
Chen C
,
Triantafillos L
,
Field JK
,
Dawn Teare MD
,
Kiemeney LA
,
Diergaarde B
,
Ferris RL
,
Zienolddiny S
,
Lam S
,
Olshan AF
,
Weissler MC
,
Lacko M
,
Risch A
,
Bickeboller H
,
Ness AR
,
Thomas S
,
Le Marchand L
,
Schabath MB
,
Wunsch-Filho V
,
Tajara EH
,
Andrew AS
,
Clifford GM
,
Lazarus P
,
Grankvist K
,
Johansson M
,
Arnold S
,
Melander O
,
Brunnstrom H
,
Boccia S
,
Cadoni G
,
Timens W
,
Obeidat M
,
Xiao X
,
Houlston RS
,
Hung RJ
,
Brennan P
(2021).
Genome-wide association meta-analysis identifies pleiotropic risk loci for aerodigestive squamous cell cancers
.
PLoS Genet
2021; 17:e1009254.
DOI
Liu G
,
Brenner H
,
Chen C
,
Christiani D
,
Field JK
,
Hung R
,
Jie Z
,
Le Marchand L
,
Ryan B
,
Schabath MB
,
Schwartz AG
,
Shete S
,
Shiraishi K
,
Tardon A
,
Teare MD
,
Yang P
,
Zhang ZF
,
Xu W
(2021).
A reply to 'Lung cancer outcomes: Are BMI and race clinically relevant?'
.
Lung Cancer
2021; doi:10.1016/j.lungcan.2021.02.019.
DOI
Garg M
,
Couturier D-L
,
Nsengimana J
,
Fonseca NA
,
Wongchenko M
,
Yan Y
,
Lauss M
,
Jönsson GB
,
Newton-Bishop J
,
Parkinson C
,
Middleton MR
,
Bishop T
,
McDonald S
,
Stefanos N
,
Tadross J
,
Vergara IA
,
Lo S
,
Newell F
,
Wilmott JS
,
Thompson JF
,
Long GV
,
Scoyler RA
,
Corrie P
,
Adams DJ
,
Brazma A
,
Rabbie R
(2021).
Tumour gene expression signature in primary melanoma predicts long-term outcomes
.
Nature Commun
2021; 12:1137.
DOI
Jiang M
,
Fares AF
,
Shepshelovich D
,
Yang P
,
Christiani D
,
Zhang J
,
Shiraishi K
,
Ryan BM
,
Chen C
,
Schwartz AG
,
Tardon A
,
Shete S
,
Schabath MB
,
Teare MD
,
Le Marchand L
,
Zhang ZF
,
Field JK
,
Brenner H
,
Diao N
,
Xie J
,
Kohno T
,
Harris CC
,
Wenzlaff AS
,
Fernandez-Tardon G
,
Ye Y
,
Taylor F
,
Wilkens LR
,
Davies M
,
Liu Y
,
Barnett MJ
,
Goodman GE
,
Morgenstern H
,
Holleczek B
,
Thomas S
,
Brown MC
,
Hung RJ
,
Xu W
,
Liu G
(2021).
The relationship between body-mass index and overall survival in non-small cell lung cancer by sex, smoking status, and race: A pooled analysis of 20,937 International lung Cancer consortium (ILCCO) patients
.
Lung Cancer
2021; 152:58-65.
DOI
Pippard BJ
,
Neal MA
,
Maunder AM
,
Hollingsworth KG
,
Biancardi A
,
Lawson RA
,
Fisher H
,
Matthews JNS
,
Simpson AJ
,
Wild JM
,
Thelwall PE
(2021).
Reproducibility of 19F‐MR ventilation imaging in healthy volunteers
.
Magn Reson Med
2021; 85:3343-52.
DOI
O'Hara J
,
Stocken DD
,
Watson GC
,
Fouweather T
,
McGlashan J
,
MacKenzie K
,
Carding P
,
Karagama Y
,
Wood R
,
Wilson JA
(2021).
Use of proton pump inhibitors to treat persistent throat symptoms: Multicentre, double blind, randomised, placebo controlled trial
.
BMJ
2021; 372:m4903.
DOI
Antonio Braga
,
Gabriela Paiva
,
Ehsan Ghorani
,
Fernanda Freitas
,
Luis Guillermo Coca Velarde
,
Baljeet Kaur
,
Nick Unsworth
,
Jingky Lozano-kuehne
,
Ana Paula Vieira dos Santos Esteves
,
Jorge Rezende Filho
,
others
(2021).
Predictors for single-agent resistance in FIGO score 5 or 6 gestational trophoblastic neoplasia: a multicentre, retrospective, cohort study
.
The Lancet Oncology
.
Cite
Wilson JA
,
Stocken DD
,
Watson GC
,
Fouweather T
,
McGlashan J
,
MacKenzie K
,
Carding P
,
Karagama Y
,
Harries M
,
Ball S
,
Khwaja S
,
Costello D
,
Wood R
,
Lecouturier J
,
O'Hara J
(2021).
Lansoprazole for persistent throat symptoms in secondary care: The TOPPITS RCT
.
Health Technol Assess
2021; 25:1-118.
DOI
Lauren R. Rodgers
,
Adam J. Streeter
,
Nan Lin
,
Willie Hamilton
,
William E. Henley
(2021).
Impact of influenza vaccination on amoxicillin prescriptions in older adults: A retrospective cohort study using primary care data
.
PLOS ONE
.
Cite
DOI
URL
Fonagy P
,
Yakeley J
,
Gardner T
,
Simes E
,
McMurran M
,
Moran P
,
Crawford M
,
Frater A
,
Barrett B
,
Cameron A
,
Wason J
,
Pilling S
,
Butler S
,
Bateman A
(2020).
Mentalization for Offending Adult Males (MOAM): Study protocol for a randomized controlled trial to evaluate mentalization-based treatment for antisocial personality disorder in male offenders on community probation
.
Trials
2020; 21:1001.
DOI
Spence S
,
Matthews JNS
,
McSweeney L
,
Rowland MK
,
Orango P
,
Adamson AJ
(2020).
Implementation of Universal Infant Free School Meals: A pilot study in NE England exploring the impact on Key Stage 1 pupil's dietary intake
.
Public Health Nutr
2020; doi:10.1017/S1368980020004875.
DOI
Ward M
,
Grayling M
,
Wason J
,
Welton NJ
,
Haji-Ali AL
,
Jalal H
,
Thom H
(2020).
PSU4 Value of information for adaptive trials: Proof of concept study in multi-arm multi-stage trials of interventions for the prevention of surgical site infections
.
Value Health
2020; 23:S738.
DOI
Amoo OS
,
Aina OO
,
Okwuraiwe AP
,
Onwuamah CK
,
Shaibu JO
,
Ige F
,
Owaneze K
,
Agboola HO
,
Kareithi DN
,
Onuigbo TI
,
Ikemefuna AS
,
Oraegbu JI
,
Odewale EO
,
Okoli LC
,
Ajibaye O
,
James AB
,
Idris G
,
Ohihoin G
,
Tijani B
,
Giwa-Tunbosun T
,
Adegbola R
,
Salako BL
,
Audu RA
(2020).
COVID-19 spread patterns is unrelated to malaria co-infections in Lagos, Nigeria
.
Adv Inf Dis
2020; 10:200-215.
DOI
Hiu SKW
,
Rabinovich A
(2020).
Lay theories and ageist attitudes at work: Essentialist beliefs about cognitive aging, fixed mindsets, and cyclical perception of time are linked to ageist attitudes toward older workers
.
J Appl Soc Psychol
2020; 51:190-207.
DOI
McClelland G
,
Wilson N
,
Shaw L
,
Grayling M
,
Haworth D
,
Price CI
(2020).
Ambulance documentation of stroke symptoms during the UK COVID-19 'Stay at Home' message
.
Emerg Med J
2020; 38:83-84.
DOI
Witham MD
,
Anderson E
,
Carroll CB
,
Dark PM
,
Down K
,
Hall AS
,
Knee J
,
Maher ER
,
Maier RH
,
Mountain GA
,
Nestor G
,
O'Brien JT
,
Oliva L
,
Wason J
,
Rochester L
(2020).
Ensuring that COVID-19 research is inclusive: Guidance from the NIHR INCLUDE project
.
BMJ Open
2020; 10:e043634.
DOI
McClelland G
,
Shaw G
,
Thompson L
,
Wilson N
,
Grayling M
(2020).
Impact of the COVID-19 lockdown on hangings attended by emergency medical services
.
Resuscitation
2020; 157:89-90.
DOI
Shelton M
,
Anene CA
,
Nsengimana J
,
Roberts W
,
Newton-Bishop J
,
Boyne JR
(2020).
The role of CAF derived exosomal microRNAs in the tumour microenvironment of melanoma
.
BBA - Rev Cancer
2021; 1875:188456.
DOI
Rodgers H
,
Bosomworth H
,
Krebs HI
,
van Wijck F
,
Howel D
,
Wilson N
,
Aird L
,
Alvarado N
,
Andole S
,
Cohen DL
,
Dawson J
,
Fernandez-Garcia C
,
Finch T
,
Ford GA
,
Francis R
,
Hogg S
,
Hughes N
,
Price CI
,
Ternent L
,
Turner DL
,
Vale L
,
Wilkes S
,
Shaw L
(2020).
Robot assisted training for the upper limb after stroke (RATULS): A multicentre randomised controlled trial
.
Health Technol Assess
2020; 24.
DOI
David J Pinato
,
Ahmed Kaseb
,
Yinghong Wang
,
Anwaar Saeed
,
David Szafron
,
Tomi Jun
,
Sirish Dharmapuri
,
Abdul Rafeh Naqash
,
Mahvish Muzaffar
,
Musharraf Navaid
,
Uqba Khan
,
ChiehJu Lee
,
Anushi Bulumulle
,
Bo Yu
,
Sonal Paul
,
Petros Fessas
,
Neil Nimkar
,
Dominik Bettinger
,
Hannah Hildebrand
,
Tiziana Pressiani
,
Yehia I Abugabal
,
Nicola Personeni
,
Yi-Hsiang Huang
,
Jingky Lozano-kuehne
,
Lorenza Rimassa
,
Celina Ang
,
Thomas U Marron
(2020).
Impact of corticosteroid therapy on the outcomes of hepatocellular carcinoma treated with immune checkpoint inhibitor therapy
.
Journal for ImmunoTherapy of Cancer
.
Cite
DOI
URL
Bosomworth H
,
Rodgers H
,
Shaw L
,
Smith L
,
Aird L
,
Howel D
,
Wilson N
,
Alvarado N
,
Andole S
,
Cohen DL
,
Dawson J
,
Fernandez-Garcia C
,
Finch T
,
Ford GA
,
Francis R
,
Hogg S
,
Hughes N
,
Price CI
,
Ternent L
,
Turner DL
,
Vale L
,
Wilkes S
,
Krebs HI
,
van Wijck F
(2020).
Evaluation of the enhanced upper limb therapy programme within the Robot-Assisted Training for the Upper Limb after Stroke trial: Descriptive analysis of intervention fidelity, goal selection and goal achievement
.
Clin Rehab
2021; 35:119-34.
DOI
Alderson H
,
Kaner E
,
McColl E
,
Howel D
,
Fouweather T
,
McGovern R
,
Copello A
,
Brown H
,
McArdle P
,
Smart D
,
Brown R
,
Lingam R
(2020).
A pilot feasibility randomised controlled trial of two behaviour change interventions compared to usual care to reduce substance misuse in looked after children and care leavers aged 12-20 years: The SOLID study
.
PLoS ONE
2020; 15:e0238286.
DOI
Lin C-J
,
Wason JMS
(2020).
Efficient analysis of time-to-event endpoints when the event involves a continuous variable crossing a threshold
.
J Stat Plan Infer
2020; 208:119-29.
DOI
Alderson H
,
Kaner E
,
Brown R
,
Howel D
,
McColl E
,
Smart D
,
Copello A
,
Fouweather T
,
McGovern R
,
Brown H
,
McArdle P
,
Lingam R
(2020).
Behaviour change interventions to reduce risky substance use and improve mental health in children in care: The SOLID three-arm feasibility RCT
.
Public Health Res
2020; 8.
DOI
Tijani O
,
Amoo OS
,
Adaramewa T
,
Kareithi DN
,
Omavuohrerhe A
,
Karera S
,
Salako BL
(2020).
Healthcare seeking behavior of citizens during pandemics: A case study of COVID-19 in Nigeria
.
Acta Sci Microbiol
2020; 3:137-52.
DOI
Law M
,
Grayling MJ
,
Mander AP
(2020).
A stochastically curtailed two-arm randomised phase II trial design for binary outcomes
.
Pharm Stat
2020; 20:212-28.
DOI
Azevedo H
,
Cavalcante Pessoa G
,
de Luna Vitorino FN
,
Nsengimana J
,
Newton-Bishop J
,
Moraes Reis E
,
Pinheiro Chagas da Cunha J
,
Galvonas Jasiulionis M
(2020).
Gene co-expression and histone modification signatures are associated with melanoma progression, epithelial-to-mesenchymal transition, and metastasis
.
Clin Epigenetics
2020; 12:127.
DOI
Campbell NR
,
Rao A
,
Zhang M
,
Baron M
,
Heilmann S
,
Deforet M
,
Kenny C
,
Ferretti L
,
Huang T-H
,
Garg M
,
Nsengimana J
,
Montal E
,
Tagore M
,
Hunter M
,
Newton-Bishop J
,
Middleton MR
,
Corrie P
,
Adams DJ
,
Rabbie R
,
Levesque MP
,
Cornell RA
,
Yanai I
,
Xavier JB
,
White RM
(2020).
Cell state diversity promotes metastasis through heterotypic cluster formation in melanoma
. bioRxiv 2020; DOI:10.1101/2020.08.24.265140.
DOI
Razvi S
,
Arnott B
,
Teare D
,
Hiu S
,
O'Brien N
,
Pearce SH
(2020).
Multinational survey of treatment practices of clinicians managing subclinical hypothyroidism in older people in 2019
.
Eur Thyroid J
2020; doi:10.1159/000509228.
DOI
Wason JMS
,
Robertson DS
(2020).
Controlling type I error rates in multi-arm clinical trials: A case for the false discovery rate
.
Pharm Stat
2020.
DOI
Sharma A
,
Glod M
,
Forster T
,
McGovern R
,
McGurk K
,
Barron Millar E
,
Meyer TD
,
Miklowitz D
,
Ryan V
,
Vale L
,
Le Couteur A
(2020).
FAB: First UK feasibility trial of a future randomised controlled trial of Family focused treatment for Adolescents with Bipolar disorder
.
Int J Bipolar Dis
2020;8:24.
DOI
Cherlin S
,
Lewis MJ
,
Plant D
,
Nair N
,
Goldmann K
,
Tzanis E
,
Barnes MR
,
McKeigue P
,
Barrett JH
,
Pitzalis C
,
Barton A
,
MATURA Consortium
,
Cordell HJ
(2020).
Investigation of genetically regulated gene expression and response to treatment in rheumatoid arthritis highlights an association between IL18RAP expression and treatment response
.
Ann Rheum Dis
2021; 79:1446-52.
DOI
McMenamin M
,
Grayling MJ
,
Berglind A
,
Wason JMS
(2020).
Increasing power in the analysis of responder endpoints in rheumatology: a software tutorial
.
medRxiv
2020.
DOI
Al Emran A
,
Nsengimana J
,
Punnia-Moorthy G
,
Schmitz U
,
Gallagher SJ
,
Newton-Bishop J
,
Tiffen JC
,
Hersey P
(2020).
Study of the female sex survival advantage in melanoma--A focus on X-linked epigenetic regulators and immune responses in two cohorts
.
Cancers
2020; 12:2082.
DOI
Cherlin S
,
Wason JMS
(2020).
Developing and testing high-efficacy patient subgroups within a clinical trial using risk scores
.
Stat Med
2020; 39:3285-98.
DOI
Mahil SK
,
Wilson N
,
Dand N
,
Reynolds NJ
,
Griffiths CEM
,
Emsley R
,
Marsden A
,
Evans I
,
Warren RB
,
Stocken D
,
Barker JN
,
Burden AD
,
Smith CH
,
BADBIR Study Group
,
PSORT Consortium
(2020).
Psoriasis treat to target: Defining outcomes in psoriasis using data from a real-world, population-based cohort study (the British Association of Dermatologists Biologics and Immunomodulators Register, BADBIR)
.
Brit J Dermatol
2020; 182:1158-66.
DOI
Stallard N
,
Hampson L
,
Benda N
,
Brannath W
,
Burnett T
,
Friede T
,
Kimani PK
,
Koenig F
,
Krisam J
,
Mozgunov P
,
Posch M
,
Wason J
,
Wassmer G
,
Whitehead J
,
Williamson SF
,
Zohar S
,
Jaki T
(2020).
Efficient adaptive designs for clinical trials of interventions for COVID-19
.
Stat Biopharm Res
2020; 12:483-97.
DOI
Siebert S
,
Pratt AG
,
Stocken DD
,
Morton M
,
Cranston A
,
Cole M
,
Frame S
,
Buckley CD
,
Ng WF
,
Filer A
,
McInnes IB
,
Isaacs JD
(2020).
Targeting the rheumatoid arthritis synovial fibroblast via cyclin dependent kinase inhibition
.
Medicine
2020; 99:e20458.
DOI
Xie X
,
Lv D
,
Zheng H
,
Zhang X
,
Han F
,
Chen J
(2020).
The associations of blood pressure parameters with all-cause and cardiovascular mortality in peritoneal dialysis patients: A cohort study in China
.
J Hypertens
2020.
Lee KM
,
Wason J
(2020).
Including non-concurrent control patients in the analysis of platform trials: Is it worth it?
.
BMC Med Res Methodol
2020; 20:165.
DOI
Dimairo M
,
Pallmann P
,
Wason J
,
Todd S
,
Jaki T
,
Julious SA
,
Mander AP
,
Weir CJ
,
Koenig F
,
Walton MK
,
Nicholl JP
,
Coates E
,
Biggs K
,
Hamasaki T
,
Proschan MA
,
Scott JA
,
Ando Y
,
Hind D
,
Altman DG
(2020).
The Adaptive designs CONSORT Extension (ACE) statement: A checklist with explanation and elaboration guideline for reporting randomised trials that use an adaptive design
.
BMJ
2020; 369:m115.
DOI
Robertson DS
,
Wason JMS
,
Bretz F
(2020).
Graphical approaches for the control of generalised error rates
.
Stat Med
2020.
DOI
Wason J
,
McMenamin M
,
Dodd S
(2020).
Analysis of responder-based endpoints: improving power through utilising continuous components
.
Trials
2020; 21:427.
DOI
Maurichi A
,
Miceli R
,
Eriksson H
,
Newton-Bishop J
,
Nsengimana J
,
Chan M
,
Hayes AJ
,
Heelan K
,
Adams D
,
Patuzzo R
,
Barretta F
,
Gallino G
,
Harwood C
,
Bergamaschi D
,
Bennett D
,
Lasithiotakis K
,
Ghiorzo P
,
Dalmasso B
,
Manganoni A
,
Consoli F
,
Mattavelli I
,
Barbieri C
,
Leva A
,
Cortinovis U
,
Espeli V
,
Mangas C
,
Quaglino P
,
Ribero S
,
Broganelli P
,
Pellacani G
,
Longo C
,
Del Forno C
,
Borgognoni L
,
Sestini S
,
Pimpinelli N
,
Fortunato S
,
Chiarugi A
,
Nardini P
,
Morittu E
,
Florita A
,
Cossa M
,
Valeri B
,
Milione M
,
Pruneri G
,
Zoras O
,
Anichini A
,
Mortarini R
,
Santinami M
(2020).
Factors affecting sentinel node metastasis in thin (T1) cutaneous melanomas: Development and external validation of a predictive nomogram
.
J Clin Oncol
2020; 38:1591-601.
DOI
Zheng H
,
Wason JMS
(2020).
Borrowing of information across patient subgroups in a basket trial based on distributional discrepancy
.
Biostatistics
2020.
DOI
Fonagy P
,
Butler S
,
Cottrell D
,
Scott S
,
Pilling S
,
Eisler I
,
Fuggle P
,
Kraam A
,
Byford S
,
Wason J
,
Smith JA
,
Anokhina A
,
Ellison R
,
Simes E
,
Ganguli P
,
Allison E
,
Goodyer IM
(2020).
Multisystemic therapy versus management as usual in the treatment of adolescent antisocial behaviour (START): 5-year follow-up of a pragmatic, randomised, controlled, superiority trial
.
Lancet Psychiat
2020; 7:P420-30.
DOI
Freeman R
,
Anne Maguire A
,
Ryan V
,
Wilson N
,
Innes NPT
,
Clarkson JE
,
McColl E
,
Marshman Z
,
Robertson M
,
Abouhajar A
,
Chadwick B
,
Deery C
,
Wong F
,
Douglas GVA
(2020).
The FiCTION trial: Child oral health-related quality of life and dental anxiety across three treatment strategies for managing caries in young children
.
Community Dent Oral
2020; 48:328-37.
DOI
Wang J
,
Patel A
,
Wason JMS
,
Newcombe PJ
(2020).
Two-stage sparse regression screening to detect biomarker-treatment interactions in randomized clinical trials
.
arXiv
2020; arXiv:2004.12028.
Brown S
,
Nixon J
,
Ransom M
,
Gilberts R
,
Dewhirst N
,
McGinnis E
,
Longo R
,
Game F
,
Bojke C
,
Chadwick P
,
Chandrasekar A
,
Chetter I
,
Collier H
,
Fernandez C
,
Homer-Vanniasinkam S
,
Jude E
,
Leigh R
,
Lomas R
,
Vowden P
,
Wason J
,
Sharples L
,
Russell D
(2020).
Multiple Interventions for Diabetic Foot Ulcer Treatment Trial (MIDFUT): Study protocol for a randomised controlled trial
.
BMJ Open
2020; 10:e035947.
DOI
Khan MH
,
Khan MS
,
Ansari ZN
,
Siddiqi TJ
,
Khan SU
,
Riaz IB
,
Asad Z
,
Mandrola J
,
Wason J
,
Warraich HJ
,
Stone GW
,
Bhatt DL
,
Kapadia SR
,
Kalra A
(2020).
Prevalence of multiplicity and appropriate adjustments among cardiovascular randomized clinical trials published in major medical journals
.
JAMA Netw Open
2020; 3:e203082.
DOI
Hester KLM
,
Ryan V
,
Newton J
,
Rapley T
,
De Soyza A
(2020).
Bronchiectasis information and education: A randomised, controlled feasibility trial
.
Trials
2020; 21:331.
DOI
Zheng H
,
Hampson LV
(2020).
A Bayesian decision-theoretic approach to incorporate preclinical information into phase I oncology trials
.
Biom J
2020; 62:1408-27.
DOI
Sebastian J. Wallace
,
Rachael Swann
,
Mhairi Donnelly
,
Linda Kemp
,
Julia Guaci
,
Aimee Murray
,
Johannes Spoor
,
Nan Lin
,
Michael Miller
,
Harry R. Dalton
,
S. Hyder Hussaini
,
Rory Gunson
,
Kenneth Simpson
,
Adrian Stanley
,
Andrew Fraser
(2020).
Mortality and morbidity of locally acquired hepatitis E in the national Scottish cohort: a multicentre retrospective study
.
Alimentary Pharmacology &$mathsemicolon$ Therapeutics
.
Cite
DOI
URL
Witham MD
,
Wason J
,
Dodds R
,
Sayer AA
(2020).
Developing a composite outcome measure for frailty prevention trials - Rationale, derivation and sample size comparison with other candidate measures
.
BMC Geriatrics
2020; 20:113.
Williamson SF
(2020).
Bayesian bandit models for the design of clinical trials
.
PhD Thesis, Lancaster University
2020; DOI:10.17635/lancaster/thesis/917.
DOI
Amin Al Olama A
,
Wason JMS
,
Tuladhar AM
,
van Leijsen EMC
,
Koini M
,
Hofer E
,
Morris RG
,
Schmidt R
,
de Leeuw F-E
,
Markus HS
(2020).
Simple MRI score aids prediction of dementia in cerebral small vessel disease
.
Neurology
2020; 94:e1294-302.
DOI
Snowden C
,
Lynch E
,
Avery L
,
Haighton C
,
Howel D
,
Mamasoula V
,
Gilvarry E
,
McColl E
,
Prentis J
,
Gerrand C
,
Steel A
,
Goudie N
,
Howe N
,
Kaner E
(2020).
Preoperative behavioural intervention to reduce drinking before elective orthopaedic surgery: The PRE-OP BIRDS feasibility RCT
.
Health Technol Assess
2020; 24.
DOI
Grayling MJ
,
Wheeler GM
(2020).
A review of available software for adaptive clinical trial design
.
Clin Trials
2020;17:323-31.
DOI
Rennie KJ
,
O'Hara J
,
Rousseau N
,
Stocken D
,
Howel D
,
Ternent L
,
Drinnan M
,
Bray A
,
Rooshenas L
,
Hamilton DW
,
Steel A
,
Fouweather T
,
Hynes A-M
,
Holstein E-M
,
Oluboyede Y
,
Abouhajar A
,
Wilson JA
,
Carrie S
,
Gardiner Q
,
Nix P
,
Leong S
,
Kara N
,
Morrison, J
,
Khwaja S
,
Maini S
,
Dooley J
,
Wilson C
,
Campbell I
,
Allen M
,
Lindley L
,
Mackintosh J
,
NAIROS Study Group
(2020).
Nasal Airway Obstruction Study (NAIROS): A phase III, open-label, mixed-methods, multicentre randomised controlled trial of septoplasty versus medical management of a septal deviation with nasal obstruction
.
Trials
2020; 21:179.
DOI
Homer T
,
Maguire A
,
Douglas GVA
,
Innes NP
,
Clarkson JE
,
Wilson N
,
Ryan V
,
McColl E
,
Robertson M
,
Vale L
(2020).
Cost-effectiveness of child caries management: A randomised controlled trial (FiCTION trial)
.
BMC Oral Health
2020; 20:45.
DOI
Grayling MJ
,
Wason JMS
(2020).
A web application for the design of multi-arm clinical trials
.
BMC Cancer
2020; 20:80.
DOI
Gallagher FA
,
Woitek R
,
McLean MA
,
Gill AB
,
Manzano Garcia R
,
Provenzano E
,
Riemer F
,
Kaggie J
,
Chhabra A
,
Ursprung S
,
Grist JT
,
Daniels CJ
,
Zaccagna F
,
Laurent M-C
,
Locke M
,
Hilborne S
,
Frary A
,
Torheim T
,
Boursnell C
,
Schiller A
,
Patterson I
,
Slough R
,
Carmo B
,
Kane J
,
Biggs H
,
Harrison E
,
Deen SS
,
Patterson A
,
Lanz T
,
Kingsbury Z
,
Ross M
,
Basu B
,
Baird R
,
Lomas DJ
,
Sala E
,
Wason J
,
Rueda OM
,
Chin S-F
,
Wilkinson IB
,
Graves MJ
,
Abraham JE
,
Gilbert FJ
,
Caldas C
,
Brindle KM
(2020).
Imaging breast cancer using hyperpolarized carbon-13 MRI
.
P Natl Acad Sci USA
2020; 117(4):2092-2098.
DOI
Matthews JNS
(2020).
Highly efficient stepped wedge designs for clusters of unequal size
.
Biometrics
2020; 76:1167-76.
DOI
Castellucci LC
,
Almeida L
,
Cherlin C
,
Fakiola M
,
Carvalho E
,
Figueiredo AB
,
Cavalcanti CM
,
Alves NS
,
Dutra WO
,
Gollob KJ
,
Cordell HJ
,
Blackwell JM
(2020).
A genome-wide association study highlights a regulatory role for IFNG-AS1 contributing to cutaneous leishmaniasis in Brazil
.
bioRxiv
2020; doi:10.1101/2020.01.13.903989.
DOI
Kachuri L
,
Johansson M
,
Rashkin SR
,
Graff RE
,
Bossé Y
,
Manem V
,
Caporaso NE
,
Landi MT
,
Christiani DC
,
Vineis P
,
Liu G
,
Scelo G
,
Zaridze D
,
Shete SS
,
Albanes D
,
Aldrich MC
,
Tardon A
,
Rennert G
,
Chen C
,
Goodman GE
,
Doherty JA
,
Bickeboller H
,
Field JK
,
Davies MP
,
Teare MD
,
Kiemeney LA
,
Bojesen SE
,
Haugen A
,
Zienolddiny S
,
Lam S
,
Le Marchand L
,
Cheng I
,
Schabath MB
,
Duell EJ
,
Andrew AS
,
Manjer J
,
Lazarus P
,
Arnold S
,
Mckay JD
,
Emami NC
,
Warkentin MT
,
Brhane Y
,
Obeidat M
,
Martin RM
,
Relton C
,
Davey-Smith G
,
Haycock PC
,
Amos CI
,
Brennan P
,
Witte JS
,
Hung RJ
(2020).
Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility
.
Nat Commun
2020; 11:27.
DOI
Maguire A
,
Clarkson JE
,
Douglas GVA
,
Ryan V
,
Homer T
,
Marshman Z
,
McColl E
,
Wilson N
,
Vale L
,
Robertson M
,
Abouhajar A
,
Holmes RD
,
Freeman R
,
Chadwick B
,
Deery C
,
Wong F
,
Innes NPT
(2020).
Best-practice prevention alone or with conventional or biological caries management for 3- to 7-year-olds: The FiCTION three-arm RCT
.
Health Technol Assess
2020; 24.
DOI
Clark E
,
Morton M
,
Sharma S
,
Fisher H
,
Howel D
,
Walker J
,
Wood R
,
Hancock H
,
Maier R
,
Marshall J
,
Bahl A
,
Crabb S
,
Jain S
,
Pedley I
,
Jones R
,
Staffurth J
,
Heer R
(2019).
Prostate cancer androgen receptor splice variant 7 biomarker study - A multicentre randomised feasibility trial of biomarker-guided personalised treatment in patients with advanced prostate cancer (the VARIANT trial) study protocol
.
BMJ Open
2019; 9(12):e034708.
DOI
McMenamin M
,
Barrett JK
,
Berglind A
,
Wason JMS
(2019).
Sample size estimation using a latent variable model for mixed outcome co-primary, multiple primary and composite endpoints
.
arXiv
2019; arXiv:1912.05258.
Holliday R
,
Chaffee B
,
Ryan V
,
McColl E
,
Preshaw PM
(2019).
Letter to the editor regarding 'Impact of cigarette smoking and vaping on the outcome of full-mouth ultrasonic scaling among patients with gingival inflammation: A prospective study'
.
Clin Oral Invest
2020; 24:517-518.
DOI
Kareithi DN
,
Salifu D
,
Owuor N
,
Subramanian S
,
Tonnang EZH
(2019).
An algorithm for data reconstruction from published articles – Application on insect life tables
.
Cogent Math Stat
2019; 6.
DOI
Wych J
,
Grayling MJ
,
Mander AP
(2019).
Sample size re-estimation in crossover trials: Application to the AIM HY-INFORM study
.
Trials
2019;20:665.
DOI
Slight SP
,
Tolley CL
,
Bates DW
,
Fraser R
,
Bigirumurame T
,
Kasim A
,
Balaskonis K
,
Narrie S
,
Heed A
,
Orav EJ
,
Watson NW
(2019).
Medication errors and adverse drug events in a UK hospital during the optimisation of electronic prescriptions: A prospective observational study
.
Lancet Digital Health
2019; 1:e403-12.
DOI
Close HJ
,
Stead LF
,
Nsengimana J
,
Reilly KA
,
Droop A
,
Wurdak H
,
Mathew RK
,
Corns R
,
Newton-Bishop J
,
Melcher AA
,
Short SC
,
Cook GP
,
Wilson EB
(2019).
Expression profiling of single cells and patient cohorts identifies multiple immunosuppressive pathways and an altered NK cell phenotype in glioblastoma
.
Clin Exp Immunol
2019; 200:33-44.
DOI
Papamalis FE
,
Kalyva E
,
Teare MD
,
Meier PS
(2019).
The role of personality functioning in drug misuse treatment engagement
.
Addiction
2019; 115:726-39.
DOI
Innes NP
,
Clarkson JE
,
Douglas GVA
,
Ryan V
,
Wilson N
,
Homer T
,
Marshman Z
,
McColl E
,
Vale L
,
Robertson M
,
Abouhajar A
,
Holmes RD
,
Freeman R
,
Chadwick B
,
Deery C
,
Wong F
,
Maguire A
(2019).
Child caries management: A randomized controlled trial in dental practice
.
J Dent Res
2020; 99(1):36-43.
DOI
Murray J
,
Griffin C
,
Gulliford S
,
Syndikus I
,
Staffurth J
,
Panades M
,
Scrase C
,
Parker C
,
Khoo V
,
Dean J
,
Mayles H
,
Mayles P
,
Thomas S
,
Naismith O
,
Baker A
,
Mossop H
,
Cruickshank C
,
Hall E
,
Dearnaley D
,
CHHiP Investigators
(2019).
A randomised assessment of image guided radiotherapy within a phase 3 trial of conventional or hypofractionated high dose intensity modulated radiotherapy for prostate cancer
.
Radiother Oncol
2020; 142:62-71.
DOI
Muralidhar S
,
Filia A
,
Nsengimana J
,
Pozniak J
,
O'Shea SJ
,
Diaz JM
,
Harland M
,
Randerson-Moor JA
,
Reichrath J
,
Laye JP
,
van der Weyden L
,
Adams DJ
,
Bishop DT
,
Newton-Bishop J
(2019).
Vitamin D–VDR signaling inhibits Wnt/β-Catenin–mediated melanoma progression and promotes antitumor immunity
.
Cancer Res
2019; 79:5986-98.
DOI
Michiels S
,
Wason J
(2019).
Overestimated treatment effects in randomised phase II trials: What's up doctor?
.
Eur J Cancer
2019; 123:116-127.
DOI
Jameson SS
,
Asaad A
,
Diament M
,
Kasim A
,
Bigirumurame T
,
Baker P
,
Mason J
,
Partington P
,
Reed M
(2019).
Antibiotic-loaded bone cement is associated with a lower risk of revision following primary cemented total knee arthroplasty
.
Bone Joint J
2019; 101-B:1331-47.
DOI
Razvi S
,
Ryan V
,
Ingoe L
,
Pearce SHS
,
Wilkes S
(2019).
Age-related serum hyroid-stimulating hormone reference range in older patients treated with levothyroxine: A randomized controlled feasibility trial (SORTED 1)
.
Eur Thyroid J
2020; 9:40-8.
DOI
Spence S
,
Matthews JNS
,
McSweeney L
,
Rowland M
,
Orango P
,
Adamson AJ
(2019).
A natural experimental evaluation of the effect of universal infant free school meals on key stage 1 pupil′s dietary intake in northeast England: A pilot study
.
Lancet
2019; 394:S87.
DOI
Rohini Sharma
,
Pablo Oriol Valls
,
Marianna Inglese
,
Suraiya Dubash
,
Michelle Chen
,
Hani Gabra
,
Ana Montes
,
Amarnath Challapalli
,
Mubarik Arshad
,
George Tharakan
,
Ed Chambers
,
Tom Cole
,
Jingky P. Lozano-Kuehne
,
Tara D. Barwick
,
Eric O. Aboagye
(2019).
[18F]Fluciclatide PET as a biomarker of response to combination therapy of pazopanib and paclitaxel in platinum-resistant/refractory ovarian cancer
.
European Journal of Nuclear Medicine and Molecular Imaging
.
Cite
DOI
URL
Juraleviciute M
,
Pozniak J
,
Nsengimana J
,
Harland M
,
Randerson-Moor J
,
Wernhoff P
,
Bassarova A
,
Øy GF
,
Trøen G
,
Flørenes VA
,
Bishop DT
,
Herlyn M
,
Newton-Bishop J
,
Slipicevic A
(2019).
MX 2 is a novel regulator of cell cycle in melanoma cells
.
Pigm Cell Melanoma R
2019; 33:446-57.
DOI
Alkazemi B
,
O'Shea S
,
Laye J
,
Elliott F
,
Nsengimana J
,
Bishop D
,
Treanor D
,
Merchant W
,
Newton-Bishop J
(2019).
A higher percentage of stroma within primary melanomas is associated with a protective effect on melanoma-specific survival
.
J Am Acad Dermatol
2019; 81:AB6.
DOI
Pilbery R
,
Teare MD
(2019).
PP14 Soiled airway tracheal intubation and the effectiveness of decontamination (SATIATED) by paramedics: A randomised controlled manikin study
.
Emerg Med J
2019; 36:e7.
DOI
Nethononda RM
,
McGurk KA
,
Whitworth P
,
Francis J
,
Mamasoula C
,
Cordell HJ
,
Neubauer S
,
Keavney BD
,
Mayosi BM
,
Farrall M
,
Watkins H
(2019).
Marked variation in heritability estimates of left ventricular mass depending on modality of measurement
.
Sci Rep
2019; 9:13556.
DOI
Tsakok T
,
Wilson N
,
Dand N
,
Loeff FC
,
Bloem K
,
Baudry D
,
Duckworth M
,
Pan S
,
Pushpa-Rajah A
,
Standing JF
,
de Vries A
,
Alsharqi A
,
Becher G
,
Murphy R
,
Wahie S
,
Wright A
,
Griffiths CEM
,
Reynolds NJ
,
Barker J
,
Warren RB
,
Burden AD
,
Rispens T
,
Stocken D
,
Smith C
,
for the British Association of Dermatologists Biologic and Immunomodulators Register (BADBIR) Study Group and the Psoriasis Stratification to Optimise Relevant Therapy (PSORT) Consortium
(2019).
Association of serum ustekinumab levels with clinical response in psoriasis
.
JAMA Dermatol
2019; 155:1235–43.
DOI
Thakur R
,
Laye JP
,
Lauss M
,
Diaz JMS
,
O'Shea SJ
,
Pozniak J
,
Filia A
,
Harland M
,
Gascoyne J
,
Randerson-Moor JA
,
Chan M
,
Mell T
,
Jönsson G
,
Bishop DT
,
Newton-Bishop J
,
Barrett JH
,
Nsengimana J
(2019).
Transcriptomic analysis reveals prognostic molecular signatures of stage I melanoma
.
Clin Cancer Res
2019; 25:7424-35.
DOI
Grayling MJ
,
Mander AP
,
Wason JMS
(2019).
Two-stage adaptive designs for three-treatment bioequivalence studies
.
Stat Biopharm Res
2019; 11:360-74.
DOI
Shepshelovich D
,
Xu W
,
Lu L
,
Fares A
,
Yang P
,
Christiani D
,
Zhang J
,
Shiraishi K
,
Ryan BM
,
Chen C
,
Schwartz AG
,
Tardon A
,
Wu X
,
Schabath MB
,
Teare MD
,
Le Marchand L
,
Zhang ZF
,
Field JK
,
Brenner H
,
Diao N
,
Xie J
,
Kohno T
,
Harris CC
,
Wenzlaff AS
,
Fernandez-Tardon G
,
Ye Y
,
Taylor F
,
Wilkens LR
,
Davies M
,
Liu Y
,
Barnett MJ
,
Goodman GE
,
Morgenstern H
,
Holleczek B
,
Brown MC
,
Liu G
,
Hung RJ
(2019).
Body mass index (BMI), BMI change, and overall survival in patients with SCLC and NSCLC: A pooled analysis of the International Lung Cancer Consortium
.
J Thorac Oncol
2019; 14:1594-607.
DOI
Wilson DT
,
Walwyn REA
,
Wason JMS
,
Brown J
,
Farrin AJ
(2019).
Bayesian design and analysis of external pilot trials for complex interventions
.
arXiv
2019; arXiv:1908.05955.
Lee KM
,
Wason J
,
Stallard N
(2019).
To add or not to add a new treatment arm to a multiarm study: A decision-theoretic framework
.
Stat Med
2019; 38:3305-21.
DOI
Pennington M
,
Ring H
,
Howlett J
,
Smith C
,
Redley M
,
Murphy C
,
Hook R
,
Platt A
,
Gilbert N
,
Jones E
,
Kelly J
,
Pullen A
,
Mander A
,
Donaldson C
,
Rowe S
,
Wason J
,
Irvine F
(2019).
The impact of an epilepsy nurse competency framework on the costs of supporting adults with epilepsy and intellectual disability: Findings from the EpAID study
.
J Intell Disabil Res
2019; 63:1391-400.
DOI
Kunadian V
,
Wilson N
,
Stocken DD
,
Ali H
,
McColl E
,
Burns G
,
Howe N
,
Fisher A
,
De Soyza A
(2019).
Antiplatelet therapy in the primary prevention of cardiovascular disease in patients with chronic obstructive pulmonary disease: A randomised controlled proof-of-concept trial
.
ERJ Open Res
2019; 5:00110-2019.
DOI
McClure ME
,
Wason J
,
Gopaluni S
,
Tieu J
,
Smith RM
,
Jayne DR
,
Jones RB
(2019).
Evaluation of PR3-ANCA status after rituximab for ANCA-associated vasculitis
.
J Clin Rheumatol
2019; 25:217-23.
DOI
Sebastian Trousil
,
Patrizia Lee
,
Robert J. Edwards
,
Lynn Maslen
,
Jingky P. Lozan-Kuehne
,
Ramya Ramaswami
,
Eric O. Aboagye
,
Stephen Clarke
,
Christopher Liddle
,
Rohini Sharma
(2019).
Altered cytochrome 2E1 and 3A P450-dependent drug metabolism in advanced ovarian cancer correlates to tumour-associated inflammation
.
British Journal of Pharmacology
.
Cite
DOI
URL
Williamson SF
,
Villar SS
(2019).
A response‐adaptive randomization procedure for multi‐armed clinical trials with normally distributed outcomes
.
Biometrics
2019; 79(1):197-209.
DOI
Dua S
,
Ruiz-Garcia M
,
Bond S
,
Durham SR
,
Kimber I
,
Mills C
,
Roberts G
,
Skypala I
,
Wason J
,
Ewan P
,
Boyle R
,
Clark A
(2019).
Effect of sleep deprivation and exercise on reaction threshold in peanut-allergic adults: A randomised controlled study
.
J Allergy Clin Immun
2019; 144:1584-94.e2.
DOI
Rodgers H
,
Bosomworth H
,
Krebs HI
,
van Wijck F
,
Howel D
,
Wilson N
,
Aird L
,
Alvarado N
,
Andole S
,
Cohen DL
,
Dawson J
,
Fernandez-Garcia C
,
Finch T
,
Ford GA
,
Francis R
,
Hogg S
,
Hughes N
,
Price CI
,
Ternent L
,
Turner DL
,
Vale L
,
Wilkes S
,
Shaw L
(2019).
Robot assisted training for the upper limb after stroke (RATULS): A multicentre randomised controlled trial
.
Lancet
2019; 394:51-62.
DOI
Palmer J
,
Lloyd A
,
Steele L
,
Fotheringham J
,
Teare D
,
Iqbal J
,
Grech ED
(2019).
Differential risk of ST-segment elevation myocardial infarction in male and female smokers
.
J Am Col Cardiol
2019; 73:3259-66.
DOI
Filia A
,
Droop A
,
Harland M
,
Thygesen H
,
Randerson-Moor J
,
Snowden H
,
Taylor C
,
Diaz JMS
,
Pozniak J
,
Nsengimana J
,
Laye J
,
Newton-Bishop JA
,
Bishop DT
(2019).
High-resolution copy number patterns from clinically relevant FFPE material
.
Sci Rep-UK
2019; 9:8098.
DOI
Grayling MJ
,
Dimairo M
,
Mander AP
,
Jaki TF
(2019).
A review of perspectives on the use of randomization in phase II oncology trials
.
JNCI: J Natl Cancer I
2019; 111:1255-62.
DOI
.bib
.enw
.ris
Grayling MJ
,
Wason JMS
,
Mander AP
(2019).
Exact group sequential designs for two-arm experiments with Poisson distributed outcome variables
.
Commun Stat Theory
.
DOI
.bib
.enw
.ris
Clearkin L
,
Ramasamy B
,
Wason J
,
Tiew S
(2019).
Anti-VEGF intervention in neovascular AMD: Benefits and risks restated as natural frequencies
.
BMJ Open Ophthal
2019; 4:e000257.
DOI
Beska B
,
Chan D
,
Gu S
,
Qiu W
,
Mossop H
,
Neely D
,
Kunadian V
(2019).
The association between vitamin D status and clinical events in high-risk older patients with non-ST elevation acute coronary syndrome undergoing invasive management
.
PLoS ONE
2019; 14:e0217476.
DOI
Varley D
,
Wright B
,
Cooper C
,
Marshall D
,
Biggs K
,
Ali S
,
Chater T
,
Coates E
,
Gilbody S
,
de la Cuesta GG
,
Kingsley E
,
Le Couteur A
,
McKelvey A
,
Shephard N
,
Teare D
(2019).
Investigating SOcial Competence and Isolation in children with Autism taking part in LEGO-based therapy clubs In School Environments (I-SOCIALISE): Study protocol
.
BMJ Open
2019; 9:e030471.
DOI
Khanna A
,
Jopson L
,
Howel D
,
Bryant A
,
Blamire A
,
Newton JL
,
Jones DE
(2019).
Rituximab is ineffective for treatment of fatigue in primary biliary cholangitis: A phase 2 randomized controlled trial
.
Hepatology
2019; 70:1646-57.
DOI
Varaljai R
,
Wistuba-Hamprecht K
,
Seremet T
,
Diaz JMS
,
Nsengimana J
,
Sucker A
,
Griewank K
,
Horn P
,
von Neuhoff N
,
Shannan B
,
Chauvistré H
,
Vogel FEC
,
Horn S
,
Becker JC
,
Newton-Bishop J
,
Stang A
,
Neyns B
,
Weide B
,
Schadendorf D
,
Roesch A
(2019).
ctDNA as a noninvasive monitoring tool in metastatic melanoma
.
J Clin Oncol
2019; 37(Suppl 15):9548.
DOI
Dai J
,
Li Z
,
Amos CI
,
Hung RJ
,
Tardon A
,
Andrew AS
,
Chen C
,
Christiani DC
,
Albanes D
,
van der Heijden EHFM
,
Duell EJ
,
Rennert G
,
Mckay JD
,
Yuan JM
,
Field JK
,
Manjer J
,
Grankvist K
,
Le Marchand L
,
Teare MD
,
Schabath MB
,
Aldrich MC
,
Tsao MS
,
Lazarus P
,
Lam S
,
Bojesen SE
,
Arnold S
,
Wu X
,
Haugen A
,
Janout V
,
Johansson M
,
Brhane Y
,
Fernandez-Somoano A
,
Kiemeney LA
,
Davies MPA
,
Zienolddiny S
,
Hu Z
,
Shen H
(2019).
Systematic analyses of regulatory variants in DNase I hypersensitive sites identified two novel lung cancer susceptibility loci
.
Carcinogenesis
2019; 40(3):432-440.
DOI
Wason J
(2019).
Design of Multi-Arm, Multi-Stage Trials in Oncology
. In
Textbook of Clinical Trials in Oncology: A Statistical Perspective
.
Zhu Y
,
Wei Y
,
Zhang R
,
Dong X
,
Shen S
,
Zhao Y
,
Bai J
,
Albanes D
,
Caporaso NE
,
Landi MT
,
Zhu B
,
Chanock SJ
,
Gu F
,
Lam S
,
Tsao M-S
,
Shepherd FA
,
Tardon A
,
Fernandez-Somoano A
,
Fernandez-Tardon G
,
Chen C
,
Barnett MJ
,
Doherty J
,
Bojesen SE
,
Brennan P
,
Mckay JD
,
Carreras-Torres R
,
Muley T
,
Risch A
,
Wichmann H-E
,
Bickeboeller H
,
Rosenberger A
,
Rennert G
,
Saliba W
,
Arnold SM
,
Field JK
,
Davies MPA
,
Marcus MW
,
Wu X
,
Ye Y
,
Le Marchand L
,
Wilkens LR
,
Melander O
,
Manjer J
,
Brunnstrom H
,
Hung RJ
,
Liu G
,
Brhane Y
,
Kachuri L
,
Andrew AS
,
Duell EJ
,
Kiemeney LA
,
van der Heijden EHFM
,
Haugen A
,
Zienolddiny S
,
Skaug V
,
Grankvist K
,
Johansson M
,
Woll PJ
,
Cox A
,
Taylor F
,
Teare DM
,
Lazarus P
,
Schabath MB
,
Aldrich MC
,
Houlston RS
,
McLaughlin J
,
Stevens VL
,
Shen H
,
Hu Z
,
Dai J
,
Amos CI
,
Han Y
,
Zhu D
,
Goodman GE
,
Chen F
,
David C Christiani
(2019).
Elevated platelet count appears to be causally associated with increased risk of lung cancer: A Mendelian randomization analysis
.
Cancer Epidemiol Biomarkers Prev
2019; 28:935-42.
DOI
Giles EL
,
McGeechan GJ
,
Coulton S
,
Deluca P
,
Drummond C
,
Howel D
,
Kaner E
,
McColl E
,
McGovern R
,
Scott S
,
Stamp E
,
Sumnall H
,
Todd L
,
Vale L
,
Albani V
,
Boniface S
,
Ferguson J
,
Gilvarry E
,
Hendrie N
,
Howe N
,
Mossop H
,
Ramsay A
,
Stanley G
,
Newbury-Birch D
(2019).
Brief alcohol intervention for risky drinking in young people aged 14–15 years in secondary schools: The SIPS JR-HIGH RCT
.
Public Health Res
2019; 7(9).
DOI
Rohini Sharma
,
Pablo Oriol Valls
,
Marianna Inglese
,
Suraiya Rahim Dubash
,
Michelle Chen
,
Hani Gabra
,
Ana Montes
,
Amarnath Challapalli
,
George Tharakan
,
Edward Chambers
,
Tom Cole
,
Jingky Lozano-kuehne
,
Tara Barwick
,
Eric Aboagye
(2019).
[$łess$sup$greater$18$łess$/sup$greater$F] Fluciclatide PET as a biomarker of clinical response to combination therapy of pazopanib and paclitaxel in patients with platinum-resistant or platinum-refractory advanced ovarian cancer: Results of a phase Ib study.
.
Journal of Clinical Oncology
.
Cite
DOI
URL
Pilbery R
,
Teare MD
(2019).
1 Soiled airway tracheal intubation and the effectiveness of decontamination (SATIATED) by paramedics: A randomised controlled manikin study
.
BMJ Open
2019; 9.
DOI
Hung RJ
,
Spitz MR
,
Houlston RS
,
Schwartz AG
,
Field JK
,
Ying J
,
Li Y
,
Han Y
,
Ji X
,
Chen W
,
Wu X
,
Gorlov IP
,
Na J
,
de Andrade M
,
Liu G
,
Brhane Y
,
Diao N
,
Wenzlaff A
,
Davies MPA
,
Liloglou T
,
Timofeeva M
,
Muley T
,
Rennert H
,
Saliba W
,
Ryan BM
,
Bowman E
,
Barros-Dios JM
,
Pérez-Ríos M
,
Morgenstern H
,
Zienolddiny S
,
Skaug V
,
Ugolini D
,
Bonassi S
,
van der Heijden EHFM
,
Tardon A
,
Bojesen SE
,
Landi MT
,
Johansson M
,
Bickeboller H
,
Arnold S
,
Le Marchand L
,
Melander O
,
Andrew A
,
Grankvist K
,
Caporaso N
,
Teare MD
,
Schabath MB
,
Aldrich MC
,
Kiemeney LA
,
Wichmann HE
,
Lazarus P
,
Mayordomo J
,
Neri M
,
Haugen A
,
Zhang ZF
,
Ruano-Ravina A
,
Brenner H
,
Harris CC
,
Orlow I
,
Rennert G
,
Risch A
,
Brennan P
,
Christiani DC
,
Amos CI
,
Yang P
,
Gorlova OY
(2019).
Lung cancer risk in never-smokers of European descent is associated With genetic variation in the 5p15.33 TERT-CLPTM1Ll region
.
J Thorac Oncol
2019; 14:1360-9.
DOI
Dutta P
,
Funston W
,
Mossop H
,
Ryan V
,
Jones R
,
Forbes R
,
Sen S
,
Pearson J
,
Griffin M
,
Smith J
,
Ward C
,
Forrest I
,
Simpson J
(2019).
Randomised, double-blind, placebo-controlled pilot trial of omeprazole in idiopathic pulmonary fibrosis
.
Thorax
2019; 74:346-53.
DOI
Heaps S
,
Nye T
,
Boys R
,
Williams T
,
Cherlin S
,
Embley M
(2019).
Generalizing rate heterogeneity across sites in statistical phylogenetics
.
Stat Model
2019.
DOI
Li Y
,
Xiao X
,
Bossé Y
,
Gorlova O
,
Gorlov I
,
Han Y
,
Byun J
,
Leighl N
,
Johansen JS
,
Barnett M
,
Chen C
,
Goodman G
,
Cox A
,
Taylor F
,
Woll P
,
Wichmann HE
,
Manz J
,
Muley T
,
Risch A
,
Rosenberger A
,
Han J
,
Siminovitch K
,
Arnold SM
,
Haura EB
,
Bolca C
,
Holcatova I
,
Janout V
,
Kontic M
,
Lissowska J
,
Mukeria A
,
Ognjanovic S
,
Orlowski TM
,
Scelo G
,
Swiatkowska B
,
Zaridze D
,
Bakke P
,
Skaug V
,
Zienolddiny S
,
Duell EJ
,
Butler LM
,
Houlston R
,
Artigas MS
,
Grankvist K
,
Shepherd FA
,
Marcus MW
,
Brunnstrom H
,
Manjer J
,
Melander O
,
Muller DC
,
Overvad K
,
Trichopoulou A
,
Tumino R
,
Liu G
,
Bojesen SE
,
Wu X
,
Le Marchand L
,
Albanes D
,
Bickeboller H
,
Aldrich MC
,
Bush WS
,
Tardon A
,
Rennert G
,
Teare MD
,
Field JK
,
Kiemeney LA
,
Lazarus P
,
Haugen A
,
Lam S
,
Schabath MB
,
Andrew AS
,
Bertazzi PA
,
Pesatori AC
,
Christiani DC
,
Caporaso N
,
Johansson M
,
Mckay JD
,
Brennan P
,
Hung RJ
,
Amos CI
(2019).
Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development
.
Oncotarget
2019; 10:1760-74.
DOI
Grayling MJ
,
Mander AP
,
Wason JMS
(2019).
Admissible multiarm stepped‐wedge cluster randomized trial designs
.
Stat Med
2019; 38:1103-19.
DOI
.bib
.enw
.ris
Kasza J
,
Hemming K
,
Hooper R
,
Matthews JNS
,
Forbes AB
(2019).
Impact of non-uniform correlation structure on sample size and power in multiple-period cluster randomised trials
.
Stat Methods Med Res
2019; 28:703-16.
DOI
Lee KM
,
Wason J
(2019).
Design of experiments for a confirmatory trial of precision medicine
.
J Stat Plan Infer
2019; 199:179-187.
DOI
Candlish J
,
Teare MD
,
Cowen J
,
Bywater T
(2019).
Statistical design and analysis in trials of proportionate interventions: A systematic review
.
Trials
2019; 20:151.
DOI
Wason JMS
,
Seaman SR
(2019).
A latent variable model for improving inference in trials assessing the effect of dose on toxicity and composite efficacy endpoints
.
Stat Meth Med Res
2020; 29:230-42.
DOI
McMenamin M
,
Barrett JK
,
Berglind A
,
Wason JMS
(2019).
Employing latent variable models to improve efficiency in composite endpoint analysis
.
arXiv
2019; arXiv:1902.07037.
Pozniak J
,
Nsengimana J
,
Laye JP
,
O'Shea SJ
,
Diaz JMS
,
Droop AP
,
Filia A
,
Harland M
,
Davies JR
,
Mell T
,
Randerson-Moor JA
,
Muralidhar S
,
Hogan SA
,
Freiberger SN
,
Levesque MP
,
Cook GP
,
Bishop DT
,
Newton-Bishop J
(2019).
Genetic and environmental determinants of immune response to cutaneous melanoma
.
Cancer Res
2019; 79(10):2684-2696.
DOI
Gu SZ
,
Beska B
,
Chan D
,
Neely D
,
Batty JA
,
Adams-Hall J
,
Mossop H
,
Qiu W
,
Kunadian V
(2019).
Cognitive decline in older patients with non-ST elevation acute coronary syndrome
.
J Am Heart Assoc
2019; 8(4):e011218.
DOI
Varaljai R
,
Wistuba-Hamprecht K
,
Seremet T
,
Diaz JMS
,
Nsengimana J
,
Sucker A
,
Griewank K
,
Placke J-M
,
Horn PA
,
von Neuhoff N
,
Shannan B
,
Chauvistré H
,
Vogel FCE
,
Horn S
,
Becker JC
,
Newton-Bishop J
,
Stang A
,
Neyns B
,
Weide B
,
Schadendorf D
,
Roesch A
(2019).
Application of Circulating cell-free tumor DNA profiles for therapeutic monitoring and outcome prediction in genetically heterogeneous metastatic melanoma
.
JCO Prec Oncol
2019; 3:1-10.
DOI
Robertson DS
,
Wason JMS
(2019).
Familywise error control in multi-armed response-adaptive trials
.
Biometrics
2019; 75:885-94.
DOI
Grayling MJ
,
Mander AP
(2019).
Re-formulating Gehan's design as a flexible two-stage single-arm trial
.
BMC Med Res Methodol
2019; 19:22.
DOI
.bib
.enw
.ris
Jiang X
,
Finucane HK
,
Schumacher FR
,
Schmit SL
,
Tyrer JP
,
Han Y
,
Michailidou K
,
Lesseur C
,
Kuchenbaecker KB
,
Dennis J
,
Conti DV
,
Casey G
,
Gaudet MM
,
Huyghe JR
,
Albanes D
,
Aldrich MC
,
Andrew AS
,
Andrulis IL
,
Anton-Culver H
,
Antoniou AC
,
Antonenkova NN
,
Arnold SM
,
Aronson KJ
,
Arun BK
,
Bandera EV
,
Barkardottir RB
,
Barnes DR
,
Batra J
,
Beckmann MW
,
Benitez J
,
Benlloch S
,
Berchuck A
,
Berndt SI
,
Bickeboller H
,
Bien SA
,
Blomqvist C
,
Boccia S
,
Bogdanova NV
,
Bojesen SE
,
Bolla MK
,
Brauch H
,
Brenner H
,
Brenton JD
,
Brook MN
,
Brunet J
,
Brunnstrom H
,
Buchanan DD
,
Burwinkel B
,
Butzow R
,
Cadoni G
,
Caldés T
,
Caligo MA
,
Campbell I
,
Campbell PT
,
Cancel-Tassin G
,
Cannon-Albright L
,
Campa D
,
Caporaso N
,
Carvalho AL
,
Chan AT
,
Chang-Claude J
,
Chanock SJ
,
Chen C
,
Christiani DC
,
Claes KBM
,
Claessens F
,
Clements J
,
Collée JM
,
Correa MC
,
Couch FJ
,
Cox A
,
Cunningham JM
,
Cybulski C
,
Czene K
,
Daly MB
,
deFazio A
,
Devilee P
,
Diez O
,
Gago-Dominguez M
,
Donovan JL
,
Dörk T
,
Duell EJ
,
Dunning AM
,
Dwek M
,
Eccles DM
,
Edlund CK
,
Edwards DRV
,
Ellberg C
,
Evans DG
,
Fasching PA
,
Ferris RL
,
Liloglou T
,
Figueiredo JC
,
Fletcher O
,
Fortner RT
,
Fostira F
,
Franceschi S
,
Friedman E
,
Gallinger SJ
,
Ganz PA
,
Garber J
,
García-Sáenz JA
,
Gayther SA
,
Giles GG
,
Godwin AK
,
Goldberg MS
,
Goldgar DE
,
Goode EL
,
Goodman MT
,
Goodman G
,
Grankvist K
,
Greene MH
,
Gronberg H
,
Gronwald J
,
Guénel P
,
Håkansson N
,
Hall P
,
Hamann U
,
Hamdy FC
,
Hamilton RJ
,
Hampe J
,
Haugen A
,
Heitz F
,
Herrero R
,
Hillemanns P
,
Hoffmeister M
,
Høgdall E
,
Hong YC
,
Hopper JL
,
Houlston R
,
Hulick PJ
,
Hunter DJ
,
Huntsman DG
,
Idos G
,
Imyanitov EN
,
Ingles SA
,
Isaacs C
,
Jakubowska A
,
James P
,
Jenkins MA
,
Johansson M
,
John EM
,
Joshi AD
,
Kaneva R
,
Karlan BY
,
Kelemen LE
,
Kühl T
,
Khaw KT
,
Khusnutdinova E
,
Kibel AS
,
Kiemeney LA
,
Kim J
,
Kjaer SK
,
Knight JA
,
Kogevinas M
,
Kote-Jarai Z
,
Koutros S
,
Kristensen VN
,
Kupryjanczyk J
,
Lacko M
,
Lam S
,
Lambrechts D
,
Landi MT
,
Lazarus P
,
Le ND
,
Lee E
,
Lejbkowicz F
,
Lenz HJ
,
Leslie G
,
Lessel D
,
Lester J
,
Levine DA
,
Li L
,
Li CI
,
Lindblom A
,
Lindor NM
,
Liu G
,
Loupakis F
,
Lubiński J
,
Maehle L
,
Maier C
,
Mannermaa A
,
Le Marchand L
,
Margolin S
,
May T
,
McGuffog L
,
Meindl A
,
Middha P
,
Miller A
,
Milne RL
,
MacInnis RJ
,
Modugno F
,
Montagna M
,
Moreno V
,
Moysich KB
,
Mucci L
,
Muir K
,
Mulligan AM
,
Nathanson KL
,
Neal DE
,
Ness AR
,
Neuhausen SL
,
Nevanlinna H
,
Newcomb PA
,
Newcomb LF
,
Nielsen FC
,
Nikitina-Zake L
,
Nordestgaard BG
,
Nussbaum RL
,
Offit K
,
Olah E
,
Olama AAA
,
Olopade OI
,
Olshan AF
,
Olsson H
,
Osorio A
,
Pandha H
,
Park JY
,
Pashayan N
,
Parsons MT
,
Pejovic T
,
Penney KL
,
Peters WHM
,
Phelan CM
,
Phipps AI
,
Plaseska-Karanfilska D
,
Pring M
,
Prokofyeva D
,
Radice P
,
Stefansson K
,
Ramus SJ
,
Raskin L
,
Rennert G
,
Rennert HS
,
Van Rensburg EJ
,
Riggan MJ
,
Risch HA
,
Risch A
,
Roobol MJ
,
Rosenstein BS
,
Rossing MA
,
De Ruyck K
,
Saloustros E
,
Sandler DP
,
Sawyer EJ
,
Schabath MB
,
Schleutker J
,
Schmidt MK
,
Setiawan VW
,
Shen H
,
Siegel EM
,
Sieh W
,
Singer CF
,
Slattery ML
,
Sorensen K D
,
Southey MC
,
Spurdle AB
,
Stanford JL
,
Stevens VL
,
Stintzing S
,
Stone J
,
Sundfeldt K
,
Sutphen R
,
Swerdlow AJ
,
Tajara EH
,
Tangen CM
,
Tardon A
,
Taylor JA
,
Teare MD
,
Teixeira MR
,
Terry MB
,
Terry KL
,
Thibodeau SN
,
Thomassen M
,
Bjørge L
,
Tischkowitz M
,
Toland AE
,
Torres D
,
Townsend PA
,
Travis RC
,
Tung N
,
Tworoger SS
,
Ulrich CM
,
Usmani N
,
Vachon CM
,
Van Nieuwenhuysen E
,
Vega A
,
Aguado-Barrera ME
,
Wang Q
,
Webb PM
,
Weinberg CR
,
Weinstein S
,
Weissler MC
,
Weitzel JN
,
West CML
,
White E
,
Whittemore AS
,
Wichmann HE
,
Wiklund F
(2019).
Shared heritability and functional enrichment across six solid cancers
.
Nat Commun
2019; 10:431.
DOI
Cole M
,
Hynes AM
,
Howel D
,
Hall L
,
Abinun M
,
Allahabadia A
,
Barrett T
,
Boelaert K
,
Drake AJ
,
Dimitri P
,
Kirk J
,
Zammitt N
,
Pearce S
,
Cheetham T
(2019).
Adjuvant rituximab, a potential treatment for the young patient with Graves' hyperthyroidism (RiGD): Study protocol for a single-arm, single-stage, phase II trial
.
BMJ Open
2019; 9:e024705.
DOI
Zheng H
,
Hampson L
,
Wandel S
(2019).
A robust Bayesian meta-analytic approach to incorporate animal data into phase I oncology trials
.
Stat Meth Med Res
2019; 29:94-110.
DOI
Mason KJ
,
Williams S
,
Yiu ZZN
,
McElhone K
,
Ashcroft DM
,
Kleyn CE
,
Jabbar-Lopez ZK
,
Owen CM
,
Reynolds NJ
,
Smith CH
,
Wilson N
,
Warren RB
,
Griffiths CEM
(2019).
Persistence and effectiveness of nonbiologic systemic therapies for moderate-to-severe psoriasis in adults: A systematic review
.
Brit J Dermatol
2019; 181:256-64.
DOI
Wason JMS
,
Brocklehurst P
,
Yap C
(2019).
When to keep it simple - Adaptive designs are not always useful
.
BMC Medicine
2019; 17:152.
DOI
Wilkinson N
,
Tsakok T
,
Dand N
,
Bloem K
,
Duckworth M
,
Baudry D
,
Pushpa-Rajah A
,
Griffiths CEM
,
Reynolds NJ
,
Barker J
,
Warren RB
,
Burden AD
,
Rispens T
,
Stocken D
,
Smith C
(2019).
Defining the therapeutic range for adalimumab and predicting response in psoriasis: A multicenter prospective observational cohort study
.
J Invest Dermatol
2019; 139:115-23.
DOI
Antoniou M
,
Kolamunnage-Dona R
,
Wason J
,
Bathia R
,
Billingham C
,
Bliss JM
,
Brown LC
,
Gillman A
,
Paul J
,
Jorgensen AL
(2019).
Biomarker-guided trials: Challenges in practice
.
Contemp Clin Trials Commun
2019; 16:100493.
DOI
Andrews M
,
Iqbal J
,
Wall JJ
,
Teare D
,
El-Omar M
,
Fath-Ordoubadi F
,
Gunn J
(2018).
Development and validation of a novel risk score for primary percutaneous coronary intervention for ST elevation myocardial infarction
.
Cardiovasc Revasc Med
2018; 20:980-4.
DOI
Alblooshi H
,
Al Safar H
,
Fisher HF
,
Cordell HJ
,
El Kashef A
,
Al Ghaferi H
,
Shawky M
,
Reece S
,
Hulse GK
,
Tay GK
(2018).
A case–control genome wide association study of substance use disorder (SUD) identifies novel variants on chromosome 7p14.1 in patients from the United Arab Emirates (UAE)
.
Am J Med Genet B
2019; 180:68-79.
DOI
Hegade VS
,
Mells GF
,
Fisher H
,
Kendrick S
,
DiBello J
,
Gilchrist K
,
Alexander GJ
,
Hirschfield GM
,
Sandford RN
,
Jones DEJ
(2018).
Pruritus is common and undertreated in patients with primary biliary cholangitis in the United Kingdom
.
Clin Gastroenterol H
2019; 17:1379-87.e3.
DOI
Adams N
,
Skelton DA
,
Howel D
,
Bailey C
,
Lampitt R
,
Fouweather T
,
Gray J
,
Coe D
,
Wilkinson J
,
Gawler S
,
de Jong LD
,
Waterman H
,
Deary V
,
Clarke M
,
Parry SW
(2018).
Feasibility of trial procedures for a randomised controlled trial of a community based group exercise intervention for falls prevention for visually impaired older people: The VIOLET study
.
BMC Geriatr
2018; 18:307.
DOI
Grayling MJ
,
Mander AP
(2018).
Calculations involving the multivariate normal and multivariate t distributions with and without truncation
.
Stata J
2018; 18:826-43.
DOI
.bib
.enw
.ris
Thomas Jaki
,
Wason JMS
(2018).
Multi-arm multi-stage trials can improve the efficiency of finding effective treatments for stroke: A case study
.
BMC Cardiovasc Disord
2018; 18:215.
DOI
Dimairo M
,
Coates E
,
Pallmann P
,
Todd S
,
Julious SA
,
Jaki T
,
Wason J
,
Mander AP
,
Weir CJ
,
Koenig F
,
Walton MK
,
Biggs K
,
Nicholl J
,
Hamasaki T
,
Proschan MA
,
Scott JA
,
Ando Y
,
Hind D
,
Altman DG
(2018).
Development process of a consensus-driven CONSORT extension for randomised trials using an adaptive design
.
BMC Med
2018; 16:210.
DOI
Hemming K
,
Taljaard M
,
McKenzie J
,
Hooper R
,
Copas A
,
Thompson J
,
Dixon-Woods M
,
Aldcroft A
,
Doussau A
,
Grayling M
,
Kristunas C
,
Goldstein C
,
Girling A
,
Eldridge S
,
Campbell M
,
Lilford R
,
Weijer C
,
Forbes A
,
Grimshaw J
(2018).
Reporting of the CONSORT extension for stepped-wedge cluster randomised trials: Extension of the CONSORT 2010 statement with explanation and elaboration
.
BMJ
2018; 363:k1614.
DOI
.bib
.enw
.ris
Forbes R
,
Ali A
,
Abouhajar A
,
Brennand C
,
Brown H
,
Carnell S
,
Chadwick T
,
Eardley I
,
Lecouturier J
,
Mossop H
,
Pearce I
,
Pickard R
,
Thiruchelvam N
,
Walton K
,
Wilkinson J
,
Harding C
(2018).
ALternatives To prophylactic Antibiotics for the treatment of Recurrent urinary tract infection in women (ALTAR): Study protocol for a multicentre, pragmatic, patient-randomised, non-inferiority trial
.
Trials
2018; 19:616.
DOI
Cherlin S
,
Plant D
,
Taylor JC
,
Colombo M
,
Spiliopoulou A
,
Tzanis E
,
Morgan AW
,
Barnes MR
,
McKeigue P
,
Barrett JH
,
Pitzalis C
,
Barton A
,
MATURA Consortium
,
Cordell HJ
(2018).
Prediction of treatment response in rheumatoid arthritis patients using genome-wide SNP data
.
Genetic Epidemiology
2018; 42:754-71.
DOI
Candlish J
,
Teare MD
,
Dimairo M
,
Flight L
,
Mandefield L
,
Walters S
(2018).
Appropriate statistical methods for analysing partially nested randomised controlled trials with continuous outcomes: A simulation study
.
BMC Med Res Methodol
2018; 18:105.
DOI
Grayling MJ
,
Wason JMS
,
Mander AP
(2018).
Group sequential crossover trial designs with strong control of the familywise error rate
.
Sequential Anal
2018; 37:174-203.
DOI
.bib
.enw
.ris
Ferreiro-Iglesias A
,
Lesseur C
,
McKay J
,
Hung RJ
,
Han Y
,
Zong X
,
Christiani D
,
Xiao X
,
Li Y
,
Qian DC
,
Ji X
,
Liu G
,
Caporaso N
,
Scelo G
,
Zaridze D
,
Mukeriya A
,
Kontic M
,
Ognjanovic S
,
Lissowska J
,
Szolkowska M
,
Swiatkowska B
,
Janout V
,
Holcatova I
,
Bolca C
,
Savic M
,
Ognjanovic M
,
Bojesen SE
,
Wu X
,
Albanes D
,
Aldrich MC
,
Tardon A
,
Fernandez-Somoano A
,
Fernandez-Tardon G
,
Le Marchand L
,
Rennert G
,
Chen C
,
Doherty J
,
Goodman G
,
Bickeboller H
,
Wichmann HE
,
Risch A
,
Rosenberger A
,
Shen H
,
Dai J
,
Field JK
,
Davies M
,
Woll P
,
Teare MD
,
Kiemeney LA
,
van der Heijden EHFM
,
Yuan JM
,
Hong YC
,
Haugen A
,
Zienolddiny S
,
Lam S
,
Tsao MS
,
Johansson M
,
Grankvist K
,
Schabath MB
,
Andrew A
,
Duell E
,
Melander O
,
Brunnstrom H
,
Lazarus P
,
Arnold S
,
Slone S
,
Byun J
,
Kamal A
,
Zhu D
,
Landi MT
,
Amos CI
,
Brennan P
(2018).
Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity
.
Nat Commun
2018; 9:3927.
DOI
Pereira DIA
,
Mohammed Ni
,
Ofordile O
,
Camara F
,
Baldeh B
,
Mendy T
,
Sanyang C
,
Jallow AT
,
Hossain I
,
Wason J
,
Prentice AM
(2018).
A novel nano-iron supplement to safely combat iron deficiency and anaemia in young children: The IHAT-GUT double-blind, randomised, placebo-controlled trial protocol
.
Gates Open Res
2018; 2:48.
DOI
Dyson JK
,
Wong LL
,
Bigirumurame T
,
Hirschfield GM
,
Kendrick S
,
Oo YH
,
Lohse AW
,
Heneghan MA
,
Jones DEJ
,
UK-AIH Consortium
(2018).
Inequity of care provision and outcome disparity in autoimmune hepatitis in the United Kingdom
.
Aliment Pharm Ther
2018; 48:951-60.
DOI
Cherlin S
,
Howey RAJ
,
Cordell HJ
(2018).
Using penalized regression to predict phenotype from SNP data
.
BMC Proc
2018; 12:38.
DOI
Evangelou E
,
Warren HR
,
Mosen-Ansorena D
,
Mifsud B
,
Pazoki R
,
Gao H
,
Ntritsos G
,
Dimou N
,
Cabrera CP
,
Karaman I
,
Ng FL
,
Evangelou M
,
Witkowska K
,
Tzanis E
,
Hellwege JN
,
Giri A
,
Velez Edwards DR
,
Sun YV
,
Cho K
,
Gaziano JM
,
Wilson PWF
,
Tsao PS
,
Kovesdy CP
,
Esko T
,
Magi R
,
Milani L
,
Almgren P
,
Boutin T
,
Debette S
,
Ding J
,
Giulianini F
,
Holliday EG
,
Jackson AU
,
Li-Gao R
,
Lin WY
,
Luan J
,
Mangino M
,
Oldmeadow C
,
Prins BP
,
Qian Y
,
Sargurupremraj M
,
Shah N
,
Surendran P
,
Theriault S
,
Verweij N
,
Willems SM
,
Zhao JH
,
Amouyel P
,
Connell J
,
de Mutsert R
,
Doney ASF
,
Farrall M
,
Menni C
,
Morris AD
,
Noordam R
,
Pare G
,
Poulter N
,
Shields DC
,
Stanton A
,
Thom S
,
Abecasis G
,
Amin N
,
Arking DE
,
Ayers KL
,
Barbieri CM
,
Batini C
,
Bis JC
,
Blake T
,
Bochud M
,
Boehnke M
,
Boerwinkle E
,
Boomsma DI
,
Bottinger EP
,
Braund PS
,
Brumat M
,
Campbell A
,
Campbell H
,
Chakravarti A
,
Chambers JC
,
Chauhan G
,
Ciullo M
,
Cocca M
,
Collins F
,
Cordell HJ
,
Davies G
,
de Borst MH
,
de Geus EJ
,
Deary IJ
,
Deelen J
,
Del Greco MF
,
Demirkale CY
,
Dorr M
,
Ehret GB
,
Elosua R
,
Enroth S
,
Erzurumluoglu M
,
Ferreira T
,
Franberg M
,
Franco OH
,
Gandin I
,
Gasparini P
,
Giedraitis V
,
Gieger C
,
Girotto G
,
Goel A
,
Gow AJ
,
Gudnason V
,
Guo X
,
Gyllensten U
,
Hamsten A
,
Harris TB
,
Harris SE
,
Hartman CA
,
Havulinna AS
,
Hicks AA
,
Hofer E
,
Hofman A
,
Hottenga JJ
,
Huffman JE
,
Hwang SJ
,
Ingelsson E
,
James A
,
Jansen R
,
Jarvelin MR
,
Joehanes R
,
Johansson A
,
Johnson AD
,
Joshi PK
,
Jousilahti P
,
Jukema JW
,
Jula A
,
Kähönen M
,
Kathiresan S
,
Keavney BD
,
Khaw KT
,
Knekt P
,
Knight J
,
Kolcic I
,
Kooner JS
,
Koskinen S
,
Kristiansson K
,
Kutalik Z
,
Laan M
,
Larson M
,
Launer LJ
,
Lehne B
,
Lehtimäki T
,
Liewald DCM
,
Lin L
,
Lind L
,
Lindgren CM
,
Liu YM
,
Loos RJF
,
Lopez LM
,
Lu Y
,
Lyytikainen LP
,
Mahajan A
,
Mamasoula C
,
Marrugat J
,
Marten J
,
Milaneschi Y
,
Morgan A
,
Morris AP
,
Morrison AC
,
Munson PJ
,
Nalls MA
,
Nandakumar P
,
Nelson CP
,
Niiranen T
,
Nolte IM
,
Nutile T
,
Oldehinkel AJ
,
Oostra BA
,
O'Reilly PF
,
Org E
,
Padmanabhan S
,
Palmas W
,
Palotie A
,
Pattie A
,
Penninx BWJH
,
Perola M
,
Peters A
,
Polasek O
,
Pramstaller PP
,
Nguyen QT
,
Raitakari OT
,
Ren M
,
Rettig R
,
Rice K
,
Ridker PM
,
Ried JS
,
Riese H
,
Ripatti S
,
Robino A
,
Rose LM
,
Rotter JI
,
Rudan I
,
Ruggiero D
,
Saba Y
,
Sala CF
,
Salomaa V
,
Samani NJ
,
Sarin AP
,
Schmidt R
,
Schmidt H
,
Shrine N
,
Siscovick D
,
Smith AV
,
Snieder H
,
Sober S
,
Sorice R
,
Starr JM
,
Stott DJ
,
Strachan DP
,
Strawbridge RJ
,
Sundstrom J
,
Swertz MA
,
Taylor KD
,
Teumer A
,
Tobin MD
,
Tomaszewski M
,
Toniolo D
,
Traglia M
,
Trompet S
,
Tuomilehto J
,
Tzourio C
,
Uitterlinden AG
,
Vaez A
,
van der Most PJ
,
van Duijn CM
,
Vergnaud AC
,
Verwoert GC
,
Vitart V
,
Volker U
,
Vollenweider P
,
Vuckovic D
,
Watkins H
,
Wild SH
,
Willemsen G
,
Wilson JF
,
Wright AF
,
Yao J
,
Zemunik T
,
Zhang W
,
Attia JR
,
Butterworth AS
,
Chasman DI
,
Conen D
,
Cucca F
,
Danesh J
,
Hayward C
,
Howson JMM
,
Laakso M
,
Lakatta EG
,
Langenberg C
,
Melander O
,
Mook-Kanamori DO
,
Palmer CNA
,
Risch L
,
Scott RA
,
Scott RJ
,
Sever P
,
Spector TD
,
van der Harst P
,
Wareham NJ
,
Zeggini E
,
Levy D
,
Munroe PB
,
Newton-Cheh C
,
Brown MJ
,
Metspalu A
,
Hung AM
,
O'Donnell CJ
,
Edwards TL
,
Psaty BM
,
Tzoulaki I
,
Barnes MR
,
Wain LV
,
Elliott P
,
Caulfield MJ
,
Million Veteran Program
(2018).
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits
.
Nat Genet
2018; 50:1412–25.
DOI
Cherlin S
,
Wang MH
,
Bickeboller H
,
Cantor RM
(2018).
Detecting responses to treatment with fenofibrate in pedigrees
.
BMC Genet
2018; 19:64.
DOI
Grayling MJ
,
Mander AP
,
Wason JMS
(2018).
Blinded and unblinded sample size reestimation procedures for stepped-wedge cluster randomized trials
.
Biom J
2018; 60:903-16.
DOI
.bib
.enw
.ris
Grayling MJ
,
Mander AP
,
Wason JMS
(2018).
Blinded and unblinded sample size reestimation in crossover trials balanced for period
.
Biom J
2018; 60:917-33.
DOI
.bib
.enw
.ris
Silva S
,
Danson S
,
Teare D
,
Taylor F
,
Bradford J
,
McDonagh AJG
,
Salawu A
,
Wells G
,
Burghel GJ
,
Brock I
,
Connley D
,
Cramp H
,
Hughes D
,
Tiffin N
,
Cox A
(2018).
Genome-wide analysis of circulating cell-free DNA copy number detects active melanoma and predicts survival
.
Clin Chem
2018; 64:1338-46.
DOI
Fisher H
,
Oluboyede Y
,
Chadwick T
,
Abdel-Fattah M
,
Brennand C
,
Fader M
,
Harrison S
,
Hilton P
,
Larcombe J
,
Little P
,
McClurg D
,
McColl E
,
N'Dow J
,
Ternent L
,
Thiruchelvam N
,
Timoney A
,
Vale L
,
Walton K
,
von Wilamowitz-Moellendorff A
,
Wilkinson J
,
Wood R
,
Pickard R
(2018).
Continuous low-dose antibiotic prophylaxis for adults with repeated urinary tract infections (AnTIC): A randomised, open-label trial
.
Lancet Infect Dis
2018; 18:957-68.
DOI
Wright BD
,
Cooper C
,
Scott AJ
,
Tindall L
,
Ali S
,
Bee P
,
Biggs K
,
Breckman T
,
Davis TE III
,
Gega L
,
Hargate RJ
,
Lee E
,
Lovell K
,
Marshall D
,
McMillan D
,
Teare MD
,
Wilson J
(2018).
Clinical and cost-effectiveness of one-session treatment (OST) versus multisession cognitive-behavioural therapy (CBT) for specific phobias in children: Protocol for a non-inferiority randomised controlled trial
.
BMJ Open
2018; 8(8):e025031.
DOI
Pinder EM
,
Rostron AJ
,
Hellyer TP
,
Ruchaud-Sparagano M-H
,
Scott J
,
Macfarlane JG
,
Wiscombe S
,
Widdrington JD
,
Roy AI
,
Linnett VC
,
Baudouin SV
,
Wright SE
,
Chadwick T
,
Fouweather T
,
Juss JK
,
Chilvers ER
,
Bowett SA
,
Parker J
,
McAuley DF
,
Conway Morris A
,
Simpson AJ
(2018).
Randomised controlled trial of GM-CSF in critically ill patients with impaired neutrophil phagocytosis
.
Thorax
2018; 73:918-25.
DOI
Uwatoko T
,
Luo Y
,
Sakata M
,
Kobayashi D
,
Sakagami Y
,
Takemoto K
,
Collins LM
,
Watkins E
,
Hollon SD
,
Wason J
,
Noma H
,
Horikoshi M
,
Kawamura T
,
Iwami T
,
Furukawa TA
(2018).
Healthy Campus Trial: A multiphase optimization strategy (MOST) fully factorial trial to optimize the smartphone cognitive behavioral therapy (CBT) app for mental health promotion among university students: Study protocol for a randomized controlled trial
.
Trials
2018; 19:353.
DOI
Rosenberger A
,
Hung RJ
,
Christiani DC
,
Caporaso NE
,
Liu G
,
Bojesen SE
,
Le Marchand L
,
Haiman CA
,
Albanes D
,
Aldrich MC
,
Tardon A
,
Fernandez-Tardon G
,
Rennert G
,
Field JK
,
Kiemeney B
,
Lazarus P
,
Haugen A
,
Zienolddiny S
,
Lam S
,
Schabath MB
,
Andrew AS
,
Brunnsstöm H
,
Goodman GE
,
Doherty JA
,
Chen C
,
Teare MD
,
Wichmann HE
,
Manz J
,
Risch A
,
Muley TR
,
Johansson M
,
Brennan P
,
Landi MT
,
Amos CI
,
Pesch B
,
Johnen G
,
Brüning T
,
Bickeboller H
,
Gomolka M
(2018).
Genetic modifiers of radon-induced lung cancer risk: A genome-wide interaction study in former uranium miners
.
Int Arch Occ Env Hea
2018; 91:937-50.
DOI
Muralidhar S
,
Nsengimana J
,
Pozniak J
,
O'Shea S
,
Laye J
,
Adams D
,
van der Weyden L
,
Bishop T
,
Newton-Bishop J
(2018).
Primary melanoma expression of the vitamin D receptor (VDR) is protective for melanoma survival and is associated with increased tumor immune response, decreased Wnt/B-catenin signaling and tumor proliferation
.
Tumor Biol
2018; 78:Abstract 5205.
DOI
Pozniak J
,
Nsengimana J
,
Laye J
,
O'Shea S
,
Schindler S
,
Levesque M
,
Bishop T
,
Newton-Bishop J
(2018).
MYCexpression and smoking as drivers of failure of immune response to melanoma
.
Tumor Biol
2018; 78:Abstract 5204.
DOI
Granic A
,
Mossop H
,
Engstrom G
,
Davies K
,
Dodds R
,
Galvin J
,
Ouslander JG
,
Tappen R
,
Sayer AV
(2018).
Factors associated with physical performance measures in a multiethnic cohort of older adults
.
Gerontology Geriatr Med
2018; DOI:10.1177/2333721418778623.
DOI
Kachuri L
,
Saarela O
,
Bojesen SE
,
Davey-Smith G
,
Liu G
,
Landi MT
,
Caporaso NE
,
Christiani DC
,
Johansson M
,
Panico S
,
Overvad K
,
Trichopoulou A
,
Vineis P
,
Scelo G
,
Zaridze D
,
Wu X
,
Albanes D
,
Diergaarde B
,
Lagiou P
,
Macfarlane GJ
,
Aldrich MC
,
Tardon A
,
Rennert G
,
Olshan AF
,
Weissler MC
,
Chen C
,
Goodman GE
,
Doherty JA
,
Ness AR
,
Bickeboller H
,
Wichmann H-E
,
Risch A
,
Field JK
,
Teare MD
,
Kiemeney LA
,
van der Heijden EHFM
,
Carroll JC
,
Haugen A
,
Zienolddiny S
,
Skaug V
,
Wunsch-Filho V
,
Tajara EH
,
Ayoub Moyses R
,
Daumas Nunes F
,
Lam S
,
Eluf-Neto J
,
Lacko M
,
Peters WHM
,
Le Marchand L
,
Duell EJ
,
Andrew AS
,
Franceschi S
,
Schabath MB
,
Manjer J
,
Arnold S
,
Lazarus P
,
Mukeriya A
,
Swiatkowska B
,
Janout V
,
Holcatova I
,
Stojsic J
,
Mates D
,
Lissowska J
,
Boccia S
,
Lesseur C
,
Zong X
,
Mckay JD
,
Brennan P
,
Amos CI
,
Hung RJ
(2018).
Mendelian Randomization and mediation analysis of leukocyte telomere length and risk of lung and head and neck cancers
.
Int J Epidemiol
2019; 48:751-66.
DOI
Grayling MJ
,
Wason JMS
,
Mander AP
(2018).
Group sequential clinical trial designs for normally distributed outcome variables
.
Stata J
2018; 18:416-31.
DOI
.bib
.enw
.ris
Boys RJ
,
Ainsworth HF
,
Gillespie CS
(2018).
Bayesian inference for a partially observed birth–death process using data on proportions
.
Aust NZ J Stat
2018; 60:157-73.
DOI
Kunadian V
,
Chan D
,
Ali H
,
Wilkinson N
,
Howe N
,
McColl E
,
Thornton J
,
von Wilamowitz-Moellendorff A
,
Holstein E-M
,
Burns G
,
Fisher A
,
Stocken D
,
De Soyza A
(2018).
Antiplatelet therapy in the primary prevention of cardiovascular disease in patients with chronic obstructive pulmonary disease: Protocol of a randomised controlled proof-of-concept trial (APPLE COPD-ICON 2)
.
BMJ Open
2018; 8:e020713.
DOI
McMenamin M
,
Berglind A
,
Wason JMS
(2018).
Improving the analysis of composite endpoints in rare disease trials
.
Orphanet J Rare Dis
2018; 13:81.
DOI
Pickard R
,
Chadwick T
,
Oluboyede Y
,
Brennand C
,
von Wilamowitz-Moellendorff A
,
McClurg D
,
Wilkinson J
,
Ternent L
,
Fisher H
,
Walton K
,
McColl E
,
Vale L
,
Wood R
,
Abdel-Fattah M
,
Hilton P
,
Fader M
,
Harrison S
,
Larcombe J
,
Little P
,
Timoney A
,
N'Dow J
,
Armstrong H
,
Morris N
,
Walker K
,
Thiruchelvam N
(2018).
Continuous low-dose antibiotic prophylaxis to prevent urinary tract infection in adults who perform clean intermittent self-catheterisation: The AnTIC RCT
.
Health Technol Assess
2018; 22.
DOI
Wong LL
,
Fisher HF
,
Stocken DD
,
Rice S
,
Khanna A
,
Heneghan MA
,
Oo YH
,
Mells G
,
Kendrick S
,
Dyson JK
,
Jones DEJ
,
UK-AIH Consortium
(2018).
The impact of autoimmune hepatitis and its treatment on health utility
.
Hepatology
2018; 68:1487-97.
DOI
Nsengimana J
,
Laye J
,
Filia A
,
O'Shea S
,
Muralidhar S
,
Pozniak J
,
Droop A
,
Chan M
,
Walker C
,
Parkinson L
,
Gascoyne J
,
Mell T
,
Polso M
,
Jewell R
,
Randerson-Moor J
,
Cook GP
,
Bishop DT
,
Newton-Bishop J
(2018).
β-Catenin–mediated immune evasion pathway frequently operates in primary cutaneous melanomas
.
J Clin Invest
2018; 128:2048-63.
DOI
Paleri V
,
Patterson J
,
Rousseau N
,
Moloney E
,
Craig D
,
Tzelis D
,
Wilkinson N
,
Franks J
,
Hynes AM
,
Heaven B
,
Hamilton D
,
Guerrero-Urbano T
,
Donnelly R
,
Barclay S
,
Rapley T
,
Stocken D
(2018).
Gastrostomy versus nasogastric tube feeding for chemoradiation patients with head and neck cancer: The TUBE pilot RCT
.
Health Technol Assess
2018; 22(16).
DOI
Parr JR
,
Todhunter E
,
Pennington L
,
Stocken D
,
Cadwgan J
,
O'Hare AE
,
Tuffrey C
,
Williams J
,
Cole M
,
Colver AF
(2018).
Drooling Reduction Intervention randomised trial (DRI): Comparing the efficacy and acceptability of hyoscine patches and glycopyrronium liquid on drooling in children with neurodisability
.
Arch Dis Child
2018; 103:371-6.
DOI
Grayling MJ
,
Wason JMS
,
Mander AP
(2018).
An optimised multi-arm multi-stage clinical trial design for unknown variance
.
Contemp Clin Trials
2018; 67:116-20.
DOI
.bib
.enw
.ris
Li Y
,
Xiao X
,
Han Y
,
Gorlova O
,
Qian D
,
Leighl N
,
Johansen JS
,
Barnett M
,
Chen C
,
Goodman G
,
Cox A
,
Taylor F
,
Woll P
,
Wichmann H-E
,
Manz J
,
Muley T
,
Risch A
,
Rosenberger A
,
Arnold SM
,
Haura EB
,
Bolca C
,
Holcatova I
,
Janout V
,
Kontic M
,
Lissowska J
,
Mukeria A
,
Ognjanovic S
,
Orlowski TM
,
Scelo G
,
Swiatkowska B
,
Zaridze D
,
Bakke P
,
Skaug V
,
Zienolddiny S
,
Duell EJ
,
Butler LM
,
Houlston R
,
Artigas MS
,
Grankvist K
,
Shepherd FA
,
Marcus MW
,
Brunnstrom H
,
Manjer J
,
Melander O
,
Muller DC
,
Overvad K
,
Trichopoulou A
,
Tumino R
,
Liu G
,
Bojesen SE
,
Wu X
,
Le Marchand L
,
Albanes D
,
Bickeboller H
,
Aldrich MC
,
Bush WS
,
Tardon A
,
Rennert G
,
Teare MD
,
Field JK
,
Kiemeney LA
,
Lazarus P
,
Haugen A
,
Lam S
,
Schabath MB
,
Andrew AS
,
Bertazzi PA
,
Pesatori AC
,
Christiani DC
,
Caporaso N
,
Johansson M
,
Mckay JD
,
Brennan P
,
Hung RJ
,
Amos CI
(2018).
Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population
.
Carcinogenesis
2018; 39:336-46.
DOI
Villar SS
,
Bowden J
,
Wason J
(2018).
Response‐adaptive designs for binary responses: How to offer patient benefit while being robust to time trends?
.
Pharm Stat
2018; 17:182-97.
DOI
Silva S
,
Cox A
,
Teare D
,
Bradford J
,
Brock I
,
Connley D
,
Jarratt E
,
Parker M
,
Cramp H
,
Danson S
(2018).
Copy-number profiles from circulating cell-free DNA as a potential biomarker in melanoma
.
Eur J Surg Oncol
2018; 44:S26-7.
DOI
Pallmann P
,
Bedding A
,
Choodari-Oskooei B
,
Dimairo M
,
Flight L
,
Hampson L
,
Holmes J
,
Mander AP
,
Odondi L
,
Sydes MR
,
Villar SS
,
Wason JMS
,
Weir CJ
,
Wheeler GM
,
Yap C
,
Jaki T
(2018).
Adaptive designs in clinical trials: Why use them, and how to run and report them
.
BMC Med
2018; 16:29.
DOI
Litchfield K
,
Loveday C
,
Levy M
,
Dudakia D
,
Rapley E
,
Nsengimana J
,
Bishop DT
,
Reid A
,
Huddart R
,
Broderick P
,
Houlston RS
,
Turnbull C
(2018).
Large-scale sequencing of testicular germ cell tumour (TGCT) cases excludes major TGCT predisposition gene
.
Eur Urol
2018; 73:828-31.
DOI
Mateo J
,
Cheng HH
,
Beltran H
,
Dolling D
,
Xu W
,
Pritchard CC
,
Mossop H
,
Rescigno P
,
Perez-Lopez R
,
Sailer V
,
Kolinsky M
,
Balasopoulou A
,
Bertan C
,
Nanus DM
,
Tagawa ST
,
Thorne H
,
Montgomery B
,
Carreira S
,
Sandhu S
,
Rubin MA
,
Nelson PS
,
de Bono JS
(2018).
Clinical outcome of prostate cancer patients with germline DNA repair mutations: Retrospective analysis from an international study
.
Eur Urol
2018; 73:687-93.
DOI
Hester KLM
,
Newton J
,
Rapley T
,
Ryan V
,
De Soyza A
(2018).
Information and education provision in bronchiectasis: Co-development and evaluation of a novel patient-driven resource in a digital era
.
Eur Respir J
2018; 51:1702402.
DOI
Phua AKS
,
Hiu SKW
,
Goh WK
,
Ikram MK
,
Venketasubramanian N
,
Tan BY
,
Chen CLH
,
Xu X
(2018).
Low accuracy of brief cognitive tests in tracking longitudinal cognitive decline in an Asian elderly cohort
.
J Alzheimer’s Dis
2018; 62:409-16.
DOI
Ring H
,
Howlett J
,
Pennington M
,
Smith C
,
Redley M
,
Murphy C
,
Hook R
,
Platt A
,
Gilbert N
,
Jones E
,
Kelly J
,
Pullen A
,
Mander A
,
Donaldson C
,
Rowe S
,
Wason J
,
Irvine F
(2018).
Training nurses in a competency framework to support adults with epilepsy and intellectual disability: The EpAID cluster RCT
.
Health Technol Assess
2018; 22:1-104.
DOI
Fonagy P
,
Butler S
,
Cottrell D
,
Scott S
,
Pilling S
,
Eisler I
,
Fuggle P
,
Kraam A
,
Byford S
,
Wason J
,
Ellison R
,
Simes E
,
Ganguli P
,
Allison E
,
Goodyer IM
(2018).
Multisystemic therapy versus management as usual in the treatment of adolescent antisocial behaviour (START): A pragmatic, randomised controlled, superiority trial
.
Lancet Psychiatry
2018; 5:119-33.
DOI
McClurg D
,
Walker K
,
Pickard R
,
Hilton P
,
Ainsworth H
,
Leonard K
,
Suresh S
,
Nilsson A
,
Gillespie N
(2018).
Participant experiences of clean intermittent self-catheterisation, urinary tract infections and antibiotic use on the ANTIC trial – A qualitative study
.
Int J Nurs Stud
2018; 81:1-7.
DOI
Yadegarfar ME
,
Jagger C
,
Duncan R
,
Fouweather T
,
Hanratty B
,
Parker S
,
Robinson L
(2018).
Use of primary care and other healthcare services between age 85 and 90 years: Longitudinal analysis of a single-year birth cohort, the Newcastle 85+ study
.
BMJ Open
2018; 8:e019218.
DOI
Jenkinson MD
,
Barone DG
,
Bryant A
,
Vale L
,
Bulbeck H
,
Lawrie TA
,
Hart MG
,
Watts C
(2018).
Intraoperative imaging technology to maximise extent of resection for glioma
.
Cochrane Database Syst Rev
2018; 1:CD012788.
DOI
Parsons NR
,
Teare MD
,
Sitch AJ
(2018).
Unit of analysis issues in laboratory-based research
.
eLife
2018; 7:e32486.
DOI
Lin C-J
,
Wason JMS
(2017).
Improving phase II oncology trials using best observed RECIST response as an endpoint by modelling continuous tumour measurements
.
Stat Med
2017; 36:4616-26.
DOI
Rundle S
,
Halvorsrud K
,
Bizzarri N
,
Ratnavelu NDG
,
Fisher AD
,
Ang C
,
Bryant A
,
Naik R
,
Kucukmetin A
(2017).
Sentinel node biopsy for diagnosis of pelvic lymph node involvement in early stage cervical cancer
.
Cochrane Database Syst Rev
2017; 12:CD007925.
DOI
Brass D
,
Fouweather T
,
Stocken DD
,
MacDonald C
,
Wilkinson J
,
Lloyd J
,
Farr PM
,
Reynolds NJ
,
Hampton PJ
(2017).
An observer-blinded randomized controlled pilot trial comparing localized immersion psoralen–ultraviolet A with localized narrowband ultraviolet B for the treatment of palmar hand eczema
.
Brit J Dermatol
2018; 179:63-71.
DOI
Metri R
,
Mohan A
,
Nsengimana J
,
Pozniak J
,
Molina-Paris C
,
Newton-Bishop J
,
Bishop D
,
Chandra N
(2017).
Identification of a gene signature for discriminating metastatic from primary melanoma using a molecular interaction network approach
.
Sci Rep-UK
2017; 7.
DOI
Soomro N
,
Lecouturier J
,
Stocken DD
,
Shen J
,
Hynes AM
,
Ainsworth HF
,
Breen D
,
Oades G
,
Rix D
,
Aitchison M
(2017).
Surveillance versus ablation for incidentally diagnosed small renal tumours: The SURAB feasibility RCT
.
Health Technol Assess
2017; 21.
DOI
Del Castillo Velasco-Herrera M
,
van der Weyden L
,
Nsengimana J
,
Speak AO
,
Sjöberg MK
,
Bishop DT
,
Jönsson G
,
Newton-Bishop J
,
Adams DJ
(2017).
Comparative genomics reveals that loss of lunatic fringe (LFNG) promotes melanoma metastasis
.
Mol Oncol
2018; 12:239-55.
DOI
Cherlin S
,
Heaps S
,
Nye T
,
Boys R
,
Williams T
,
Embley M
(2017).
The effect of nonreversibility on inferring rooted phylogenies
.
Mol Biol Evol
2018; 35:984-1002.
DOI
Cree I
,
Uttley L
,
Buckley Woods H
,
Kikuchi H
,
Reiman A
,
Harnan S
,
Whiteman B
,
Taylor Philips S
,
Messenger M
,
Cox A
,
Teare D
,
Sheils O
,
Shaw J
,
UK Early Cancer Detection Consortium
(2017).
The evidence base for circulating tumour DNA blood-based biomarkers for the early detection of cancer: A systematic mapping review
.
BMC Cancer
2017; 17:697.
DOI
Nsengimana J
,
Bishop DT
(2017).
Design considerations for genetic linkage and association studies
.
Statistical Human Genetics
2017; 257-281.
DOI
Chander RJ
,
Lim L
,
Handa S
,
Hiu S
,
Choong A
,
Lin X
,
Singh R
,
Oh D
,
Kandiah N
(2017).
Atrial fibrillation is independently associated with cognitive impairment after ischemic stroke
.
J Alzheimer’s Dis
2017; 60:867-75.
DOI
Grayling MJ
,
Wason JMS
,
Mander AP
(2017).
Group sequential designs for stepped-wedge cluster randomised trials
.
Clin Trials
2017; 14:501-17.
DOI
.bib
.enw
.ris
Wang T
,
Moon J-Y
,
Wu Y
,
Amos CI
,
Hung RJ
,
Tardon A
,
Andrew A
,
Chen C
,
Christiani DC
,
Albanes D
,
van der Heijden EHFM
,
Duell E
,
Rennert G
,
Goodman G
,
Liu G
,
Mckay JD
,
Yuan J-M
,
Field JK
,
Manjer J
,
Grankvist K
,
Kiemeney LA
,
Le Marchand L
,
Teare MD
,
Schabath MB
,
Aldrich MC
,
Davies M
,
Johansson M
,
Tsao M-S
,
Caporaso N
,
Lazarus P
,
Lam S
,
Bojesen SE
,
Arnold S
,
Wu X
,
Zong X
,
Hong Y-C
,
Ho GYF
(2017).
Pleiotropy of genetic variants on obesity and smoking phenotypes: Results from the Oncoarray Project of The International Lung Cancer Consortium
.
PLoS One
2017; 12:e0185660.
DOI
Ranzani M
,
Kemper K
,
Michaut M
,
Krijgsman O
,
Aben N
,
Iyer V
,
Wong K
,
Roumeliotis TI
,
Del Castillo Velasco-Herrera M
,
Nsengimana J
,
Turner G
,
Thompson N
,
Shahrabi A
,
Sjoberg M
,
Rashid M
,
Speak AO
,
Grinkevich V
,
Behan F
,
Tamborero D
,
Iorio F
,
van Dongen S
,
Bignell GR
,
Alsinet C
,
Chen S
,
Supper E
,
Dutton-Regester K
,
Pritchard A
,
Wong C
,
Enright A
,
Newton-Bishop J
,
McDermott U
,
Hayward NK
,
Choudhary JS
,
Yusa K
,
Wessels L
,
Garnett MJ
,
Peeper D
,
Adams DJ
(2017).
A screen for combination therapies in BRAF/NRAS wild type melanoma identifies nilotinib plus MEK inhibitor as a synergistic combination
. bioRxiv 2017; DOI:10.1101/195354.
DOI
Taylor F
,
Bradford J
,
Woll P
,
Teare D
,
Cox A
(2017).
1283P Non-invasive detection of lung cancer by identifying copy number aberrations in circulating cell-free DNA with next generation sequencing to aid early detection
.
Ann Oncol
2017; 28:455-6.
DOI
Koliopoulos G
,
Nyaga VN
,
Santesso N
,
Bryant A
,
Martin‐Hirsch PPL
,
Mustafa RA
,
Schünemann H
,
Paraskevaidis E
,
Arbyn M
(2017).
Cytology versus HPV testing for cervical cancer screening in the general population
.
Cochrane Database Syst Rev
2017; 8:CD008587.
DOI
Matthews JNS
,
Forbes A
(2017).
Stepped wedge designs: Insights from a design of experiments perspective
.
Stat Med
2017; 36:3772-90.
DOI
Wright SE
,
Thomas K
,
Watson G
,
Baker C
,
Bryant A
,
Chadwick TJ
,
Shen J
,
Wood R
,
Wilkinson J
,
Mansfield L
,
Stafford V
,
Wade C
,
Furneval J
,
Henderson A
,
Hugill K
,
Howard P
,
Roy A
,
Bonner S
,
Baudouin S
(2017).
Intensive versus standard physical rehabilitation therapy in the critically ill (EPICC): A multicentre, parallel-group, randomised controlled trial
.
Thorax
2018; 73:213-21.
DOI
Marshall H
,
Horsley A
,
Taylor CJ
,
Smith L
,
Hughes D
,
Horn FC
,
Swift AJ
,
Parra-Robles J
,
Hughes PJ
,
Norquay G
,
Stewart NJ
,
Collier GJ
,
Teare D
,
Cunningham S
,
Aldag I
,
Wild JM
(2017).
Detection of early subclinical lung disease in children with cystic fibrosis by lung ventilation imaging with hyperpolarised gas MRI
.
Thorax
2017; 72:760-2.
DOI
Jeroen J. J. van Eijk
,
Harry R. Dalton
,
Paolo Ripellino
,
Richard G. Madden
,
Catherine Jones
,
Miriam Fritz
,
Claudio Gobbi
,
Giorgia Melli
,
Emanuela Pasi
,
Jenny Herrod
,
Rebecca F. Lissmann
,
Hamad H. Ashraf
,
Mohamed Abdelrahim
,
Omar A. B. A. L. Masri
,
Montserrat Fraga
,
David Benninger
,
Thierry Kuntzer
,
Vincent Aubert
,
Roland Sahli
,
Darius Moradpour
,
Hélène Blasco-Perrin
,
Shahram Attarian
,
Rene Gérolami
,
Philippe Colson
,
Maria T. Giordani
,
Johannes Hartl
,
Sven Pischke
,
Nan X. Lin
,
Brendan N. Mclean
,
Richard P. Bendall
,
Marcus Panning
,
Jean-Marie Peron
,
Nassim Kamar
,
Jacques Izopet
,
Bart C. Jacobs
,
Nens van Alfen
,
Baziel G. M. van Engelen
(2017).
Clinical phenotype and outcome of hepatitis E virus–associated neuralgic amyotrophy
.
Neurology
.
Cite
DOI
URL
Wall JJS
,
Iqbal J
,
Andrews M
,
Teare D
,
Ghobrial M
,
Hinton T
,
Turton S
,
Quffa L
,
El-Omar M
,
Fraser DG
,
Siotia A
,
Gunn J
(2017).
Development and validation of a clinical risk score to predict mortality after percutaneous coronary intervention
.
Open Heart
2017; 4:e000576.
DOI
Wain LV
,
Vaez A
,
Jansen R
,
Joehanes R
,
van der Most PJ
,
Erzurumluoglu AM
,
O'Reilly PF
,
Cabrera CP
,
Warren HR
,
Rose LM
,
Verwoert GC
,
Hottenga J-J
,
Strawbridge RJ
,
Esko T
,
Arking DE
,
Hwang S-J
,
Guo X
,
Kutalik Z
,
Trompet S
,
Shrine N
,
Teumer A
,
Ried JS
,
Bis JC
,
Smith AV
,
Amin N
,
Nolte IM
,
Lyytikäinen L-P
,
Mahajan A
,
Wareham NJ
,
Hofer E
,
Joshi PK
,
Kristiansson K
,
Traglia M
,
Havulinna AS
,
Goel A
,
Nalls MA
,
Sober S
,
Vuckovic D
,
Luan J
,
Del Greco FM
,
Ayers KL
,
Marrugat J
,
Ruggiero D
,
Lopez LM
,
Niiranen T
,
Enroth S
,
Jackson AU
,
Nelson CP
,
Huffman JE
,
Zhang W
,
Marten J
,
Gandin I
,
Harris SE
,
Zemunik T
,
Lu Y
,
Evangelou E
,
Shah N
,
de Borst MH
,
Mangino M
,
Prins BP
,
Campbell A
,
Li-Gao R
,
Chauhan G
,
Oldmeadow C
,
Abecasis G
,
Abedi M
,
Barbieri CM
,
Barnes MR
,
Batini C
,
Beilby J
,
Blake T
,
Boehnke M
,
Bottinger EP
,
Braund PS
,
Brown M
,
Brumat M
,
Campbell H
,
Chambers JC
,
Cocca M
,
Collins F
,
Connell J
,
Cordell HJ
,
Damman JJ
,
Davies G
,
de Geus EJ
,
de Mutsert R
,
Deelen J
,
Demirkale Y
,
Doney ASF
,
Dorr M
,
Farrall M
,
Ferreira T
,
Franberg M
,
Gao H
,
Giedraitis V
,
Gieger C
,
Giulianini F
,
Gow AJ
,
Hamsten A
,
Harris TB
,
Hofman A
,
Holliday EG
,
Hui J
,
Jarvelin M-R
,
Johansson A
,
Johnson AD
,
Jousilahti P
,
Jula A
,
Kähönen M
,
Kathiresan S
,
Khaw K-T
,
Kolcic I
,
Koskinen S
,
Langenberg C
,
Larson M
,
Launer LJ
,
Lehne B
,
Liewald DCM
,
Lin L
,
Lind L
,
Mach F
,
Mamasoula C
,
Menni C
,
Mifsud B
,
Milaneschi Y
,
Morgan A
,
Morris AD
,
Morrison AC
,
Munson PJ
,
Nandakumar P
,
Nguyen QT
,
Nutile T
,
Oldehinkel AJ
,
Oostra BA
,
Org E
,
Padmanabhan S
,
Palotie A
,
Pare G
,
Pattie A
,
Penninx BWJH
,
Poulter N
,
Pramstaller PP
,
Raitakari OT
,
Ren M
,
Rice K
,
Ridker PM
,
Riese H
,
Ripatti S
,
Robino A
,
Rotter JI
,
Rudan I
,
Saba Y
,
Pierre AS
,
Sala CF
,
Sarin A-P
,
Schmidt R
,
Scott R
,
Seelen MA
,
Shields DC
,
Siscovick D
,
Sorice R
,
Stanton A
,
Stott DJ
,
Sundstrom J
,
Swertz M
,
Taylor KD
,
Thom S
,
Tzoulaki I
,
Tzourio C
,
Uitterlinden AG
,
Volker U
,
Vollenweider P
,
Wild S
,
Willemsen G
,
Wright AF
,
Yao J
,
Theriault S
,
Conen D
,
Attia J
,
Sever P
,
Debette S
,
Mook-Kanamori DO
,
Zeggini E
,
Spector TD
,
van der Harst P
,
Palmer CNA
,
Vergnaud A-C
,
Loos RJF
,
Polasek O
,
Starr JM
,
Girotto G
,
Hayward C
,
Kooner JS
,
Lindgren CM
,
Vitart V
,
Samani NJ
,
Tuomilehto J
,
Gyllensten U
,
Knekt P
,
Deary IJ
,
Ciullo M
,
Elosua R
,
Keavney BD
,
Hicks AA
,
Scott RA
,
Gasparini P
,
Laan M
,
Liu Y
,
Watkins H
,
Hartman CA
,
Salomaa V
,
Toniolo D
,
Perola M
,
Wilson JF
,
Schmidt H
,
Zhao JH
,
Lehtimäki T
,
van Duijn CM
,
Gudnason V
,
Psaty BM
,
Peters A
,
Rettig R
,
James A
,
Jukema JW
,
Strachan DP
,
Palmas W
,
Metspalu A
,
Ingelsson E
,
Boomsma DI
,
Franco OH
,
Bochud M
,
Newton-Cheh C
,
Munroe PB
,
Elliott P
,
Chasman DI
,
Chakravarti A
,
Knight J
,
Morris AP
,
Levy D
,
Tobin MD
,
Snieder H
,
Caulfield MJ
,
Ehret GB
(2017).
Novel blood pressure locus and gene discovery using genome-wide association study and expression data sets from blood and the kidney
.
Hypertension
2017; 70:e4-19.
DOI
Ainsworth HF
,
Shin S-Y
,
Cordell HJ
(2017).
A comparison of methods for inferring causal relationships between genotype and phenotype using additional biological measurements
.
Genet Epidemiol
2017; 41:577-86.
DOI
Barrett T
,
Tanner J
,
Gill AB
,
Slough RA
,
Wason J
,
Gallagher FA
(2017).
The longitudinal effect of ejaculation on seminal vesicle fluid volume and whole-prostate ADC as measured on prostate MRI
.
Eur Radiol
2017; 27:5236-43.
DOI
Adam J. Streeter
,
Nan Xuan Lin
,
Louise Crathorne
,
Marcela Haasova
,
Christopher Hyde
,
David Melzer
,
William E. Henley
(2017).
Adjusting for unmeasured confounding in nonrandomized longitudinal studies: a methodological review
.
Journal of Clinical Epidemiology
.
Cite
DOI
URL
Chander RJ
,
Lim L
,
Handa S
,
Hiu S
,
Choong A
,
Lin X
,
Singh R
,
Oh DCT
,
Kandiah N
(2017).
[P1-505]: Atrial fibrillation in ischemic stroke survivors is independently associated with episodic memory and executive function impairments
.
Alzheimers Dement
2017;13:P486–7.
DOI
Litchfield K
,
Levy M
,
Orlando G
,
Loveday C
,
Law PJ
,
Migliorini G
,
Holroyd A
,
Broderick P
,
Karlsson R
,
Haugen TB
,
Kristiansen W
,
Nsengimana J
,
Fenwick K
,
Assiotis I
,
Kote-Jarai Z
,
Dunning AM
,
Muir K
,
Peto J
,
Eeles R
,
Easton DF
,
Dudakia D
,
Orr N
,
Pashayan N
,
Bishop DT
,
Reid A
,
Huddart RA
,
Shipley J
,
Grotmol T
,
Wiklund F
,
Houlston RS
,
Turnbull C
(2017).
Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor
.
Nat Genet
2017; 49:.
DOI
Carreras-Torres R
,
Johansson M
,
Haycock PC
,
Wade KH
,
Relton CL
,
Martin RM
,
Davey-Smith G
,
Albanes D
,
Aldrich MC
,
Andrew A
,
Arnold SM
,
Bickeboller H
,
Bojesen SE
,
Brunnstrom H
,
Manjer J
,
Bruske I
,
Caporaso NE
,
Chen C
,
Christiani DC
,
Christian WJ
,
Doherty JA
,
Duell EJ
,
Field JK
,
Davies MPA
,
Marcus MW
,
Goodman GE
,
Grankvist K
,
Haugen A
,
Hong YC
,
Kiemeney LA
,
van der Heijden EHFM
,
Kraft P
,
Johansson MB
,
Lam S
,
Landi MT
,
Lazarus P
,
Le Marchand L
,
Liu G
,
Melander O
,
Park SL
,
Rennert G
,
Risch A
,
Haura EB
,
Scelo G
,
Zaridze D
,
Mukeriya A
,
Savic M
,
Lissowska J
,
Swiatkowska B
,
Janout V
,
Holcatova I
,
Mates D
,
Schabath MB
,
Shen H
,
Tardon A
,
Teare MD
,
Woll P
,
Tsao MS
,
Wu X
,
Yuan JM
,
Hung RJ
,
Amos CI
,
McKay J
,
Brennan P
(2017).
Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study
.
PLoS One
2017; 12:e0177875.
DOI
Palmer J
,
Lloyd A
,
Steele L
,
Fotheringham J
,
Teare D
,
Iqbal J
,
Grech E
(2017).
63 Increased risk of acute st-segment myocardial?infarction in female smokers – A?contemporary demographic study
.
Heart
2017; 103:A48.
DOI
Hoo ZH
,
Candlish J
,
Teare D
(2017).
What is an ROC curve?
.
Emerg Med J
2017; 34:357-9.
DOI
Alderson H
,
McGovern R
,
Brown R
,
Howel D
,
Becker F
,
Carr L
,
Copello A
,
Fouweather T
,
Kaner E
,
McArdle P
,
McColl E
,
Shucksmith J
,
Steele A
,
Vale L
,
Lingam R
(2017).
Supporting Looked After Children and Care Leavers In Decreasing Drugs, and alcohol (SOLID): Protocol for a pilot feasibility randomised controlled trial of interventions to decrease risky substance use (drugs and alcohol) and improve mental health of look
.
Pilot Feasibility Stud
2017; 3:25.
DOI
Goodall J
,
Mateo J
,
Yuan W
,
Mossop H
,
Porta N
,
Miranda S
,
Perez-Lopez R
,
Dolling D
,
Robinson DR
,
Sandhu S
,
Fowler G
,
Ebbs B
,
Flohr P
,
Seed G
,
Rodrigues DN
,
Boysen G
,
Bertan C
,
Atkin M
,
Clarke M
,
Crespo M
,
Figueiredo I
,
Riisnaes R
,
Sumanasuriya S
,
Rescigno P
,
Zafeiriou Z
,
Sharp A
,
Tunariu N
,
Bianchini D
,
Gillman A
,
Lord CJ
,
Hall E
,
Chinnaiyan AM
,
Carreira S
,
de Bono JS
(2017).
Circulating Cell-Free DNA to Guide Prostate Cancer Treatment with PARP Inhibition
.
Cancer Discov
2017; 7:1006-17.
DOI
Bell GM
,
Anderson AE
,
Diboll J
,
Reece R
,
Eltherington O
,
Harry RA
,
Fouweather T
,
MacDonald C
,
Chadwick T
,
McColl E
,
Dunn J
,
Dickinson AM
,
Hilkens CMU
,
Isaacs JD
(2017).
Autologous tolerogenic dendritic cells for rheumatoid and inflammatory arthritis
.
Ann Rheum Dis
2017; 76:227-34.
DOI
McPherson S
,
Wilkinson N
,
Tiniakos D
,
Wilkinson J
,
Burt AD
,
McColl E
,
Stocken DD
,
Steen N
,
Barnes J
,
Goudie N
,
Stewart S
,
Bury Y
,
Mann D
,
Anstee QM
,
Day CP
(2017).
A randomised controlled trial of losartan as an anti-fibrotic agent in non-alcoholic steatohepatitis
.
PLoS ONE
2017; 12:e0175717.
DOI
Dearnaley DP
,
Mossop H
,
Syndikus I
,
Khoo V
,
Bloomfield DJ
,
Parker CC
,
Logue J
,
Scrase CD
,
Birtle AJ
,
Staffurth J
,
Malik Z
,
Panades M
,
Eswar C
,
Graham J
,
Russell JM
,
Gao A
,
Wilkins A
,
Cruickshank C
,
Griffin C
,
Hall E
(2017).
5-year patient-reported outcomes of bowel and urinary bother in the CHHiP trial (CRUK/06/016)
.
J Clin Oncology
2017; 35(Suppl 6):23.
DOI
Palmer J
,
Lloyd A
,
Steele L
,
Fotheringham J
,
Teare D
,
Iqbal J
,
Grech E
(2017).
Increased risk of acute st-segment myocardial infarction in female smokers: A contemporary demographic study
.
J Am Coll Cardiol
2017; 69:1756.
DOI
Manios Y
,
Moschonis G
,
Lambrinou CP
,
Mavrogianni C
,
Tsirigoti L
,
Hoeller U
,
Roos FF
,
Bendik I
,
Eggersdorfer M
,
Celis-Morales C
,
Livingstone KM
,
Marsaux CFM
,
Macready AL
,
Fallaize R
,
O'Donovan CB
,
Woolhead C
,
Forster H
,
Walsh MC
,
Navas-Carretero S
,
San-Cristobal R
,
Kolossa S
,
Hallmann J
,
Jarosz M
,
Surwiłło A
,
Traczyk I
,
Drevon CA
,
van Ommen B
,
Grimaldi K
,
Matthews JNS
,
Daniel H
,
Martinez JA
,
Lovegrove JA
,
Gibney ER
,
Brennan L
,
Saris WHM
,
Gibney M
,
Mathers JC
(2017).
Associations of vitamin D status with dietary intakes and physical activity levels among adults from seven European countries: The Food4Me study
.
Eur J Nutr
2017; 57:1357-68.
DOI
O'Connor JP
,
Aboagye EO
,
Adams JE
,
Aerts HJ
,
Barrington SF
,
Beer AJ
,
Boellaard R
,
Bohndiek SE
,
Brady M
,
Brown G
,
Buckley DL
,
Chenevert TL
,
Clarke LP
,
Collette S
,
Cook GJ
,
deSouza NM
,
Dickson JC
,
Dive C
,
Evelhoch JL
,
Faivre-Finn C
,
Gallagher FA
,
Gilbert FJ
,
Gillies RJ
,
Goh V
,
Griffiths JR
,
Groves AM
,
Halligan S
,
Harris AL
,
Hawkes DJ
,
Hoekstra OS
,
Huang EP
,
Hutton BF
,
Jackson EF
,
Jayson GC
,
Jones A
,
Koh DM
,
Lacombe D
,
Lambin P
,
Lassau N
,
Leach MO
,
Lee TY
,
Leen EL
,
Lewis JS
,
Liu Y
,
Lythgoe MF
,
Manoharan P
,
Maxwell RJ
,
Miles KA
,
Morgan B
,
Morris S
,
Ng T
,
Padhani AR
,
Parker GJ
,
Partridge M
,
Pathak AP
,
Peet AC
,
Punwani S
,
Reynolds AR
,
Robinson SP
,
Shankar LK
,
Sharma RA
,
Soloviev D
,
Stroobants S
,
Sullivan DC
,
Taylor SA
,
Tofts PS
,
Tozer GM
,
van Herk M
,
Walker-Samuel S
,
Wason J
,
Williams KJ
,
Workman P
,
Yankeelov TE
,
Brindle KM
,
McShane LM
,
Jackson A
,
Waterton JC
(2017).
Imaging biomarker roadmap for cancer studies
.
Nat Rev Clin Oncol
2017; 14:169-86.
DOI
Murray J
,
Dean J
,
Mossop H
,
Hall E
,
Dearnaley D
,
Gulliford S
(2017).
Effect of dose to the penile bbulb on erectile potency (EP) in prostate image-guided radiotherapy (IGRT)
.
Clin Oncol
2017 29:e86.
DOI
Payne B
,
Chadwick TJ
,
Blamire A
,
Anderson KN
,
Parikh J
,
Qian J
,
Hynes AM
,
Wilkinson J
,
Price DA
(2017).
Does efavirenz replacement improve neurological function in treated HIV infection?
.
HIV Med
2017; 18:690-5.
DOI
Khan A
,
Gao A
,
Hall E
,
Hassan S
,
Cruikshank C
,
Griffin C
,
Mossop H
,
Dearnaley D
(2017).
Do routine computed tomography scans detect early spinal cord compression in patients with castrate resistant prostate cancer? Implications for the PROMPTS trial
.
Clin Oncol
2017; 29(3):e87.
DOI
Yatawara C
,
Hiu S
,
Tan L
,
Kandiah N
(2017).
Neuropsychiatric symptoms in South-East Asian patients with mild cognitive impairment and dementia: Prevalence, subtypes, and risk factors
.
Int J Geriatr Psych
2017; 33:122-30.
DOI
Hester KLM
,
Newton J
,
Rapley T
,
Ryan V
,
De Soyza A
(2017).
M15 Evaluation of a novel intervention for patients with bronchiectasis: The bronchiectasis information and education feasibility (brief) study
.
Thorax
2017; 72:229.
DOI
Foster E
,
Hawkins A
,
Barton KL
,
Stamp E
,
Matthews JNS
,
Adamson AJ
(2017).
Development of food photographs for use with children aged 18 months to 16 years: Comparison against weighed food diaries – The Young Person's Food Atlas (UK)
.
PLoS ONE
2017; 12:e0169084.
DOI
Warren HR
,
Evangelou E
,
Cabrera CP
,
Gao H
,
Ren M
,
Mifsud B
,
Ntalla I
,
Surendran P
,
Liu C
,
Cook JP
,
Kraja AT
,
Drenos F
,
Loh M
,
Verweij N
,
Marten J
,
Karaman I
,
Segura Lepe MP
,
O'Reilly PF
,
Knight J
,
Snieder H
,
Kato N
,
He J
,
Tai ES
,
Said MA
,
Porteous D
,
Alver M
,
Poulter N
,
Farrall M
,
Gansevoort RT
,
Padmanabhan S
,
Magi R
,
Stanton A
,
Connell J
,
Bakker SJL
,
Metspalu A
,
Shields DC
,
Thom S
,
Brown M
,
Sever P
,
Esko T
,
Hayward C
,
van der Harst P
,
Saleheen D
,
Chowdhury R
,
Chambers JC
,
Chasman DI
,
Chakravarti A
,
Newton-Cheh C
,
Lindgren CM
,
Levy D
,
Kooner JS
,
Keavney B
,
Tomaszewski M
,
Samani NJ
,
Howson JMM
,
Tobin MD
,
Munroe PB
,
Ehret GB
,
Wain LV
,
The International Consortium of Blood Pressure (ICBP) 1000G Analyses
,
The CHD Exome+ Consortium
,
The ExomeBP Consortium
,
The T2D-GENES Consortium
,
The GoT2DGenes Consortium
,
The Cohorts for Heart and Ageing Research in Genome Epidemiology (CHARGE) BP Exome Consortium
,
The International Genomics of Blood Pressure (iGEN-BP) Consortium
,
The UK Biobank CardioMetabolic Consortium BP Working Group
(2017).
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk
.
Nat Genet
2017; 49:403-15.
DOI
Muralidhar S
,
Bishop T
,
Nsengimana J
,
Newton‐Bishop J
(2017).
Higher serum 25‐hydroxyvitamin D levels at melanoma diagnosis are associated with better prognosis in patients with intermediate VDR‐expressing tumours, with transcriptomic evidence for inhibition of β‐catenin signalling
.
Pigm Cell Melanoma R
2017; 30:76-156.
DOI
Grayling MJ
,
Wason JMS
,
Mander AP
(2017).
Stepped wedge cluster randomized controlled trial designs: A review of reporting quality and design features
.
Trials
2017; 18:33.
DOI
.bib
.enw
.ris
Mason S
,
Kuczawski M
,
Teare MD
,
Stevenson M
,
Goodacre S
,
Ramlakhan S
,
Morris F
,
Rothwell J
(2017).
AHEAD Study: An observational study of the management of anticoagulated patients who suffer head injury
.
BMJ Open
2017; 7:e014324.
DOI
K. J. E. Jones
,
J. J. J. Van Eijk
,
P. Ripellino
,
R. G. Madden
,
J. Herrod
,
R. Lissmann
,
G. Webb
,
M. Abdelrahim
,
H. H. Ashraf
,
O. Almasri
,
B. N. P. Mclean
,
C. Gobbi
,
D. Moradpour
,
T. Kuntzer
,
D. Benninger
,
M. Fraga
,
R. Sahli
,
J. M. Peron
,
H. Blasco-Perrin
,
J. Izopet
,
P. Colson
,
S. Attarian
,
R. Gerolami
,
J. Hartl
,
S. Pischke
,
M. T. Giordani
,
M. Fritz
,
M. Panning
,
R. P. Bendall
,
N. Lin
,
N. Van Alfen
,
B. Van Engelen
,
B. C. Jacobs
,
H. R. Dalton
(2017).
Clinical phenotype and outcome of hepatitis E virus associated neuralgic amyotrophy$mathsemicolon$ an international retrospective comparative cohort study
.
Journal of Hepatology
.
Cite
DOI
URL
Bigirumurame T
,
Kasim AS
(2017).
Can testing clinical significance reduce false positive rates in randomized controlled trials? A snap review
.
BMC Res Notes
2017; 10:775.
DOI
Kachuri L
,
Johansson M
,
Brennan P
,
Haycock P
,
Liu G
,
Landi MT
,
Christiani DC
,
Caporaso NE
,
Wu X
,
Aldrich MC
,
Albanes D
,
Tardon A
,
Rennert G
,
Chen C
,
Goodman GE
,
Doherty JA
,
Bickeboller H
,
Teare D
,
Kiemeney LA
,
Bojesen SE
,
Field JK
,
Haugen A
,
Lam S
,
Le Marchand L
,
Schabath MB
,
Andrew AS
,
Manjer J
,
Lazarus P
,
Arnold SM
,
Gaborieau V
,
Martin R
,
Relton C
,
Davey-Smith G
,
Amos CI
,
Mckay JD
,
Hung RJ
(2017).
Abstract 2292: Lung function and lung cancer risk: A Mendelian randomization study of UK Biobank cohort and the International Lung Cancer Consortium
.
Cancer Res
2017; 77:Abstract nr 2292.
DOI
Puig-Butille JA
,
Gimenez-Xavier P
,
Visconti A
,
Nsengimana J
,
Garcia-García F
,
Tell-Marti G
,
José Escamez M
,
Newton-Bishop J
,
Bataille V
,
del Río M
,
Dopazo J
,
Falchi M
,
Puig S
(2016).
Genomic expression differences between cutaneous cells from red hair color individuals and black hair color individuals based on bioinformatic analysis
.
Oncotarget
2016; 8:11589-99.
DOI
Kuczawski M
,
Stevenson M
,
Goodacre S
,
Teare MD
,
Ramlakhan S
,
Morris F
,
Mason S
(2016).
Should all anticoagulated patients with head injury receive a CT scan? Decision-analysis modelling of an observational cohort
.
BMJ Open
2016; 6:e013742.
DOI
Spencer AV
,
Harbron C
,
Mander A
,
Wason J
,
Peers I
(2016).
An adaptive design for updating the threshold value of a continuous biomarker
.
Stat Med
2016; 35:4909-23.
DOI
Lloyd A
,
Steele L
,
Fotheringham J
,
Iqbal J
,
Sultan A
,
Teare MD
,
Grech ED
(2016).
Pronounced increase in risk of acute ST-segment elevation myocardial infarction in younger smokers
.
Heart
2017; 103:586-91.
DOI
Perez-Lopez R
,
Mateo J
,
Mossop H
,
Blackledge MD
,
Collins DJ
,
Rata M
,
Morgan VA
,
Macdonald A
,
Sandhu S
,
Lorente D
,
Rescigno P
,
Zafeiriou Z
,
Bianchini D
,
Porta N
,
Hall E
,
Leach MO
,
de Bono JS
,
Koh DM
,
Tunariu N
(2016).
Diffusion-weighted imaging as a treatment response biomarker for evaluating bone metastases in prostate cancer: A pilot study
.
Radiology
2017; 283:168-77.
DOI
Fisher A
,
Andreasson A
,
Chrysos A
,
Lally J
,
Mamasoula V
,
Exley C
,
Wilkinson J
,
Qian J
,
Watson G
,
Lewington O
,
Chadwick T
,
McColl E
,
Pearce M
,
Mann K
(2016).
An observational study of donor ex vivo lung perfusion in UK lung transplantation: DEVELOP-UK
.
Health Technol Assess
2016; 20.
DOI
Barban N
,
Jansen R
,
de Vlaming R
,
Vaez A
,
Mandemakers JJ
,
Tropf FC
,
Shen X
,
Wilson JF
,
Chasman DI
,
Nolte IM
,
Tragante V
,
van der Laan SW
,
Perry JRB
,
Kong A
,
Ahluwalia TS
,
Albrecht E
,
Yerges-Armstrong L
,
Atzmon G
,
Auro K
,
Ayers K
,
Bakshi A
,
Ben-Avraham D
,
Berger K
,
Bergman A
,
Bertram L
,
Bielak LF
,
Bjornsdottir G
,
Bonder MJ
,
Broer L
,
Bui M
,
Barbieri C
,
Cavadino A
,
Chavarro JE
,
Turman C
,
Concas MP
,
Cordell HJ
,
Davies G
,
Eibich P
,
Eriksson N
,
Esko T
,
Eriksson J
,
Falahi F
,
Felix JF
,
Fontana MA
,
Franke L
,
Gandin I
,
Gaskins AJ
,
Gieger C
,
Gunderson EP
,
Guo X
,
Hayward C
,
He C
,
Hofer E
,
Huang H
,
Joshi PK
,
Kanoni S
,
Karlsson R
,
Kiechl S
,
Kifley A
,
Kluttig A
,
Kraft P
,
Lagou V
,
Lecoeur C
,
Lahti J
,
Li-Gao R
,
Lind PA
,
Liu T
,
Makalic E
,
Mamasoula C
,
Matteson L
,
Mbarek H
,
McArdle PF
,
McMahon G
,
Meddens SFW
,
Mihailov E
,
Miller M
,
Missmer SA
,
Monnereau C
,
van der Most PJ
,
Myhre R
,
Nalls MA
,
Nutile T
,
Kalafati IP
,
Porcu E
,
Prokopenko I
,
Rajan KB
,
Rich-Edwards J
,
Rietveld CA
,
Robino A
,
Rose LM
,
Rueedi R
,
Ryan KA
,
Saba Y
,
Schmidt D
,
Smith JA
,
Stolk L
,
Streeten E
,
Tönjes A
,
Thorleifsson G
,
Ulivi S
,
Wedenoja J
,
Wellmann J
,
Willeit P
,
Yao J
,
Yengo L
,
Zhao JH
,
Zhao W
,
Zhernakova DV
,
Amin N
,
Andrews H
,
Balkau B
,
Barzilai N
,
Bergmann S
,
Biino G
,
Bisgaard H
,
Bønnelykke K
,
Boomsma DI
,
Buring JE
,
Campbell H
,
Cappellani S
,
Ciullo M
,
Cox SR
,
Cucca F
,
Toniolo D
,
Davey-Smith G
,
Deary IJ
,
Dedoussis G
,
Deloukas P
,
van Duijn CM
,
de Geus EJC
,
Eriksson JG
,
Evans DA
,
Faul JD
,
Sala CF
,
Froguel P
,
Gasparini P
,
Girotto G
,
Grabe H-J
,
Greiser KH
,
Groenen PJF
,
de Haan HG
,
Haerting J
,
Harris TB
,
Heath AC
,
Heikkilä K
,
Hofman A
,
Homuth G
,
Holliday EG
,
Hopper J
,
Hyppönen E
,
Jacobsson B
,
Jaddoe VWV
,
Johannesson M
,
Jugessur A
,
Kähönen M
,
Kajantie E
,
Kardia SLR
,
Keavney B
,
Kolcic I
,
Koponen P
,
Kovacs P
,
Kronenberg F
,
Kutalik Z
,
La Bianca M
,
Lachance G
,
Iacono WG
,
Lai S
,
Lehtimäki T
,
Liewald DC
,
Lindgren CM
,
Liu Y
,
Luben R
,
Lucht M
,
Luoto R
,
Magnus P
,
Magnusson PKE
,
Martin NG
,
McGue M
,
McQuillan R
,
Medland SE
,
Meisinger C
,
Mellström D
,
Metspalu A
,
Traglia M
,
Milani L
,
Mitchell P
,
Montgomery GW
,
Mook-Kanamori D
,
de Mutsert R
,
Nohr EA
,
Ohlsson C
,
Olsen J
,
Ong KK
,
Paternoster L
,
Pattie A
,
Penninx BWJH
,
Perola M
,
Peyser PA
,
Pirastu M
,
Polasek O
,
Power C
,
Kaprio J
,
Raffel LJ
,
Räikkönen K
,
Raitakari O
,
Ridker PM
,
Ring SM
,
Roll K
,
Rudan I
,
Ruggiero D
,
Rujescu D
,
Salomaa V
,
Schlessinger D
,
Schmidt H
,
Schmidt R
,
Schupf N
,
Smit J
,
Sorice R
,
Spector TD
,
Starr JM
,
Stöckl D
,
Strauch K
,
Stumvoll M
,
Swertz MA
,
Thorsteinsdottir U
,
Thurik AR
,
Timpson NJ
,
Tung JY
,
Uitterlinden AG
,
Vaccargiu S
,
Viikari J
,
Vitart V
,
Völzke H
,
Vollenweider P
,
Vuckovic D
,
Waage J
,
Wagner GG
,
Wang JJ
,
Wareham NJ
,
Weir DR
,
Willemsen G
,
Willeit J
,
Wright AF
,
Zondervan KT
,
Stefansson K
,
Krueger RF
,
Lee JJ
,
Benjamin DJ
,
Cesarini D
,
Koellinger PD
,
den Hoed M
,
Snieder H
,
Mills MC
(2016).
Genome-wide analysis identifies 12 loci influencing human reproductive behavior
.
Nature Genet
2016; 48:1462-72.
DOI
Dastgheib SA
,
Gartland A
,
Tabei SM
,
Omrani GR
,
Teare MD
(2016).
A candidate gene association study of bone mineral density in an Iranian population
.
Front Endocrinol
2016; 7:141.
DOI
Ainsworth HF
,
Cordell HJ
(2016).
Using gene expression data to identify causal pathways between genotype and phenotype in a complex disease: Application to Genetic Analysis Workshop 19
.
BMC Proc
2016; 10:49.
DOI
Razvi S
,
Ingoe L
,
Ryan V
,
Pearce SHS
,
Wilkes S
(2016).
Study of Optimal Replacement of Thyroxine in the Elderly (SORTED) – Results from the feasibility randomised controlled trial
.
Thyroid Res
2016; 9:5.
DOI
McParlin C
,
O'Donnell A
,
Robson SC
,
Beyer F
,
Moloney E
,
Bryant A
,
Bradley J
,
Muirhead CR
,
Nelson-Piercy C
,
Newbury-Birch D
,
Norman J
,
Shaw C
,
Simpson E
,
Swallow B
,
Yates L
,
Vale L
(2016).
Treatments for hyperemesis gravidarum and nausea and vomiting in pregnancy: A systematic review
.
JAMA
2016; 316:1392-401.
DOI
O'Donnell A
,
McParlin C
,
Robson SC
,
Beyer F
,
Moloney E
,
Bryant A
,
Bradley J
,
Muirhead C
,
Nelson-Piercy C
,
Newbury-Birch D
,
Norman J
,
Simpson E
(2016).
Treatments for hyperemesis gravidarum and nausea and vomiting in pregnancy: a systematic review and economic assessment
.
Health Technol Assess
2016; 20(74).
DOI
Pazderska A
,
Oftedal BE
,
Napier CM
,
Ainsworth HF
,
Husebye ES
,
Cordell HJ
,
Pearce SHS
,
Mitchell AL
(2016).
A variant in the BACH2 gene is associated with susceptibility to autoimmune Addison's disease in humans
.
J Clin Endocr Metab
2016; 101:3865-9.
DOI
Williamson SF
,
Jacko P
,
Villar SS
,
Jaki T
(2016).
A Bayesian adaptive design for clinical trials in rare diseases
.
Comput Stat Data An
2016; 113:136-153.
DOI
Dyson JK
,
Wilkinson N
,
Jopson L
,
Mells G
,
Bathgate A
,
Heneghan MA
,
Neuberger J
,
Hirschfield GM
,
Ducker SJ
,
The UK-PBC Consortium
,
Sandford R
,
Alexander G
,
Stocken D
,
Jones DEJ
(2016).
The inter-relationship of symptom severity and quality of life in 2055 patients with primary biliary cholangitis
.
Aliment Pharm Ther
2016; 44:1039-50.
DOI
M Dawn Teare
(2016).
Scientific Publishing: Transparent reporting of research results in eLife
.
eLife
5:e21070.
DOI
Celis-Morales C
,
Livingstone KM
,
Marsaux CFM
,
Macready AL
,
Fallaize R
,
O'Donovan CB
,
Woolhead C
,
Forster H
,
Walsh MC
,
Navas-Carretero S
,
San-Cristobal R
,
Tsirigoti L
,
Lambrinou CP
,
Mavrogianni C
,
Moschonis G
,
Kolossa S
,
Hallmann J
,
Godlewska M
,
Surwiłło A
,
Traczyk I
,
Drevon CA
,
Bouwman J
,
van Ommen B
,
Grimaldi K
,
Parnell LD
,
Matthews JNS
,
Manios Y
,
Daniel H
,
Martinez JA
,
Lovegrove JA
,
Gibney ER
,
Brennan L
,
Saris WHM
,
Gibney M
,
Mathers JC
(2016).
Effect of personalized nutrition on health-related behaviour change: Evidence from the Food4me European randomized controlled trial
.
Int J Epidemiol
2016; 46:578-88.
DOI
Chen LS
,
Baker T
,
Hung RJ
,
Horton A
,
Culverhouse R
,
Hartz S
,
Saccone N
,
Cheng I
,
Deng B
,
Han Y
,
Hansen HM
,
Horsman J
,
Kim C
,
Rosenberger A
,
Aben KK
,
Andrew AS
,
Chang SC
,
Saum KU
,
Dienemann H
,
Hatsukami DK
,
Johnson EO
,
Pande M
,
Wrensch MR
,
McLaughlin J
,
Skaug V
,
van der Heijden EH
,
Wampfler J
,
Wenzlaff A
,
Woll P
,
Zienolddiny S
,
Bickeboller H
,
Brenner H
,
Duell EJ
,
Haugen A
,
Bruske I
,
Kiemeney LA
,
Lazarus P
,
Le Marchand L
,
Liu G
,
Mayordomo J
,
Risch A
,
Schwartz AG
,
Teare MD
,
Wu X
,
Wiencke JK
,
Yang P
,
Zhang ZF
,
Spitz MR
,
Amos CI
,
Bierut LJ
(2016).
Genetic risk can be decreased: Quitting smoking decreases and delays lung cancer for smokers with high and low CHRNA5 risk genotypes — A meta-analysis
.
EBioMedicine
2016; 11:219-26.
DOI
Adams N
,
Skelton D
,
Bailey C
,
Howel D
,
Coe D
,
Lampitt R
,
Wilkinson J
,
Fouweather T
,
de Jong LD
,
Gawler S
,
Deary V
,
Gray J
,
Waterman H
,
Parry SW
(2016).
Visually Impaired OLder people's Exercise programme for falls prevenTion (VIOLET): A feasibility study
.
BMJ Open
2016; 6:e011996.
DOI
Nan Xuan Lin
,
William Edward Henley
(2016).
Prior event rate ratio adjustment for hidden confounding in observational studies of treatment effectiveness: a pairwise Cox likelihood approach
.
Statistics in Medicine
.
Cite
DOI
URL
Lim L
,
Hiu S
,
Ng TP
,
Ong AP
,
Tan MP
,
Kandiah N
(2016).
P2-316: Visual Cognitive Assessment Test (VCAT): A novel tool useful for multi-lingual populations and early detection of Alzheimer′s disease with cerebrovascular disease (CVD)
.
Alzheimer Dement
2016; 12:758-61.
DOI
Kachuri L
,
Davey-Smith G
,
Liu G
,
Landi MT
,
Christiani DC
,
Caporaso NE
,
Mckay JD
,
Wu X
,
Aldrich MC
,
Rennert G
,
Teare D
,
Chen C
,
Goodman GE
,
Doherty JA
,
Field JK
,
Kiemeney LA
,
Tardon A
,
Haugen A
,
Lam S
,
Le Marchand L
,
Schabath MB
,
Andrew AS
,
Johansson M
,
Manjer J
,
Lazarus P
,
Arnold S
,
Fehringer G
,
Zong X
,
Brennan P
,
Bojesen SE
,
Amos CI
,
Hung RJ
(2016).
Abstract 817: Mendelian randomization and mediation analysis of 5p15.33, telomere length and lung cancer risk
.
Cancer Res
2016; 76:Abstract nr 817.
DOI
Ring H
,
Gilbert N
,
Hook R
,
Platt A
,
Smith C
,
Irvine F
,
Donaldson C
,
Jones E
,
Kelly J
,
Mander A
,
Murphy C
,
Pennington M
,
Pullen A
,
Redley M
,
Rowe S
,
Wason J
(2016).
Improving outcomes in adults with epilepsy and intellectual disability (EpAID) using a nurse-led intervention: Study protocol for a cluster randomised controlled trial
.
Trials
2016; 17:297.
DOI
Wason JMS
,
Jenkins M
(2016).
Improving the power of clinical trials of rheumatoid arthritis by using data on continuous scales when analysing response rates: An application of the augmented binary method
.
Rheumatology
2016; 55:1796-802.
DOI
Lauss M
,
Nsengimana J
,
Staaf J
,
Newton-Bishop J
,
Jönsson G
(2016).
Consensus of melanoma gene expression subtypes converges on biological entities
.
J Invest Dermatol
2016; 136:2502-5.
DOI
Dearnaley D
,
Syndikus I
,
Mossop H
,
Khoo V
,
Birtle A
,
Bloomfield D
,
Graham J
,
Kirkbride P
,
Logue J
,
Malik Z
,
Money-Kyrle J
,
O'Sullivan JM
,
Panades M
,
Parker C
,
Patterson H
,
Scrase C
,
Staffurth J
,
Stockdale A
,
Tremlett J
,
Bidmead M
,
Mayles H
,
Naismith O
,
South C
,
Gao A
,
Cruickshank C
,
Hassan S
,
Pugh J
,
Griffin C
,
Hall E
(2016).
Conventional versus hypofractionated high-dose intensity-modulated radiotherapy for prostate cancer: 5-year outcomes of the randomised, non-inferiority, phase 3 CHHiP trial
.
Lancet Oncol
2016; 17:1047-60.
DOI
Paleri V
,
Wood J
,
Patterson J
,
Stocken DD
,
Cole M
,
Vale L
,
Franks J
,
Guerrero-Urbano T
,
Donnelly R
,
Barclay S
,
Rapley T
,
Rousseau N
(2016).
A feasibility study incorporating a pilot randomised controlled trial of oral feeding plus pre-treatment gastrostomy tube versus oral feeding plus as-needed nasogastric tube feeding in patients undergoing chemoradiation for head and neck cancer (TUBE trial): Study protocol
.
Pilot Feasibility Stud
2016; 2:29.
DOI
Brennand C
,
von Wilamowitz-Moellendorff A
,
Dunn S
,
Wilkinson J
,
Chadwick T
,
Ternent L
,
Oluboyede Y
,
Wood R
,
Walton K
,
Fader M
,
N'Dow J
,
Abdel-Fattah M
,
McClurg D
,
Little P
,
Hilton P
,
Timoney A
,
Morris N
,
Thiruchelvam N
,
Larcombe J
,
Harrison S
,
Armstrong H
,
McColl E
,
Pickard R
(2016).
Antibiotic treatment for intermittent bladder catheterisation with once daily prophylaxis (the AnTIC study): Study protocol for a randomised controlled trial
.
Trials
2016; 17:276.
DOI
Piton N
,
Wason J
,
Colasse É
,
Cornic M
,
Sabourin J-C
(2016).
Endoplasmic reticulum stress, the unfolded protein response and development of colon adenocarcinoma
.
Virchows Arch
2016; 469:145-54.
DOI
Aspray TJ
,
Francis RM
,
McColl E
,
Chadwick T
,
Stamp E
,
Prentice A
,
Schoenmakers I
(2016).
Vitamin D supplementation for 12 months in older people prevents bone loss and suppresses parathyroid hormone levels
.
Bone Abstracts
2016; 5:P221b.
DOI
Pandit L
,
Malli C
,
Singhal B
,
Wason J
,
Malik O
,
Sawcer S
,
Ban M
,
D'Cunha A
,
Mustafa S
(2016).
HLA associations in South Asian multiple sclerosis
.
Mult Scler
2016; 22:19-24.
DOI
Watson G
,
O'Hara J
,
Carding P
,
Lecouturier J
,
Stocken D
,
Fouweather T
,
Wilson J
(2016).
TOPPITS: Trial Of Proton Pump Inhibitors in Throat Symptoms. Study protocol for a randomised controlled trial
.
Trials
2016; 17:175.
DOI
Borislava Mihaylova
,
Iryna Schlackow
,
William Herrington
,
Jingky Lozano-Kühne
,
Seamus Kent
,
Jonathan Emberson
,
Christina Reith
,
Richard Haynes
,
Alan Cass
,
Jonathan Craig
,
Alastair Gray
,
Rory Collins
,
Martin J. Landray
,
Colin Baigent
,
R. Collins
,
C. Baigent
,
M. J. Landray
,
C. Bray
,
Y. Chen
,
A. Baxter
,
A. Young
,
M. Hill
,
C. Knott
,
A. Cass
,
B. Feldt-Rasmussen
,
B. Fellström
,
D. E. Grobbee
,
C. Grönhagen-Riska
,
M. Haas
,
H. Holdaas
,
L. S. Hooi
,
L. Jiang
,
B. Kasiske
,
U. Krairittichai
,
A. Levin
,
Z. A. Massy
,
V. Tesar
,
R. Walker
,
C. Wanner
,
D. C. Wheeler
,
A. Wiecek
,
T. Dasgupta
,
W. Herrington
,
D. Lewis
,
M. Mafham
,
W. Majoni
,
C. Reith
,
J. Emberson
,
S. Parish
,
D. Simpson
,
J. Strony
,
T. Musliner
,
L. Agodoa
,
J. Armitage
,
Z. Chen
,
J. Craig
,
D. de Zeeuw
,
J. M. Gaziano
,
R. Grimm
,
V. Krane
,
B. Neal
,
V. Ophascharoensuk
,
T. Pedersen
,
P. Sleight
,
J. Tobert
,
C. Tomson
(2016).
Cost-effectiveness of Simvastatin plus Ezetimibe for Cardiovascular Prevention in CKD: Results of the Study~of~Heart~and Renal Protection (SHARP)
.
American Journal of Kidney Diseases
.
Cite
DOI
URL
Grayling MJ
,
Mander AP
(2016).
Do single-arm trials have a role in drug development plans incorporating randomised trials?
.
Pharm Stat
2016; 15:143-51.
DOI
.bib
.enw
.ris
Payne B
,
Chadwick T
,
Blamire A
,
Qian J
,
Hynes AM
,
Wilkinson J
,
Price DA
,
Anderson K
(2016).
Neurocognitive and neurometabolic effects of switch from efavirenz to ritonavir-boosted lopinavir
.
HIV Med
2016; 17:14-71.
DOI
Law LM
,
Edirisinghe N
,
Wason JMS
(2016).
Use of an embedded, micro-randomised trial to investigate non-compliance in telehealth interventions
.
Clin Trials
2016; 13:417-24.
DOI
Gray EP
,
Teare MD
,
Stevens J
,
Archer R
(2016).
Risk prediction models for lung cancer: A systematic review
.
Clin Lung Cancer
2016; 17:95-106.
DOI
Veal GJ
,
Cole M
,
Chinnaswamy G
,
Sludden J
,
Jamieson D
,
Errington J
,
Malik G
,
Hill CR
,
Chamberlain T
,
Boddy AV
(2016).
Cyclophosphamide pharmacokinetics and pharmacogenetics in children with B-cell non-Hodgkin's lymphoma
.
Eur J Cancer
2016; 55:56-64.
DOI
Jeremy G. Hunter
,
Richie G. Madden
,
Ashleigh M. Stone
,
Nick Osborne
,
Ben Wheeler
,
Louisa Vine
,
Amanda Dickson
,
Maggie Barlow
,
James Lewis
,
Richard P. Bendall
,
Nan X. Lin
,
William E. Henley
,
William H. Gaze
,
Harry R. Dalton
(2016).
Coastal clustering of HEV$mathsemicolon$ Cornwall, UK
.
European Journal of Gastroenterology &$mathsemicolon$ Hepatology
.
Cite
DOI
URL
Louis E
,
Adriaensens P
,
Guedens W
,
Bigirumurame T
,
Baeten K
,
Vanhove K
,
Vandeurzen K
,
Darquennes K
,
Vansteenkiste J
,
Dooms C
,
Shkedy Z
,
Mesotten L
,
Thomeer M
(2016).
Detection of lung cancer through metabolic changes measured in blood plasma
.
J Thorac Oncol
2016; 11:516-23.
DOI
Jagger C
,
Matthews FE
,
Wohland P
,
Fouweather T
,
Stephan BCM
,
Robinson L
,
Arthur A
,
Brayne C
(2016).
A comparison of health expectancies over two decades in England: Results of the Cognitive Function and Ageing Study I and II
.
Lancet
2016; 387:779-86.
DOI
Pilbery R
,
Teare MD
,
Goodacre S
,
Morris F
(2016).
The Recognition of STEMI by Paramedics and the Effect of Computer inTerpretation (RESPECT): A randomised crossover feasibility study
.
Emerg Med J
2016; 33:471-6.
DOI
Echevarria C
,
Brewin K
,
Horobin H
,
Bryant A
,
Corbett S
,
Steer J
,
Bourke SC
(2016).
Early supported discharge/hospital at home for acute exacerbation of chronic obstructive pulmonary disease: A review and meta-analysis
.
COPD
2016; 13:523-33.
DOI
Ball HL
,
Howel D
,
Bryant A
,
Best E
,
Russell C
,
Ward-Platt M
(2016).
Bed-sharing by breastfeeding mothers: Who bed-shares and what is the relationship with breastfeeding duration?
.
Acta Paediatr
2016; 105:628-634.
DOI
Matthews JNS
(2016).
Anticoagulation in haemodialysis in children: A thirty-period crossover trial
. In Aston P et al (eds)
UK Success Stories in Industrial Mathematics
. Springer, Cham.
DOI
Lawrie TA
,
Nordin A
,
Chakrabarti M
,
Bryant A
,
Kaushik S
,
Pepas L
(2016).
Medical and surgical interventions for the treatment of usual‐type vulval intraepithelial neoplasia
.
Cochrane Database Syst Rev
2016; 1:CD011837.
DOI
Pinder EM
,
Rostron AJ
,
Hellyer TP
,
Ruchaud-Sparagano M-H
,
Scott J
,
Macfarlane JG
,
Wiscombe S
,
Widdrington JD
,
Allen T
,
Roy AI
,
Linnett VC
,
Baudouin SV
,
Wright SE
,
Chadwick T
,
Fouweather A
,
Bowett S
,
Parker J
,
Corris PA
,
McAuley DF
,
Morris AC
,
Simpson AJ
(2016).
Randomised controlled trial of granulocyte macrophage colony stimulating factor in critically ill patients with impaired neutrophil function
.
Am J Resp Crit Care
2016; 201:A2727.
Jeremy G Hunter
,
Richie G Madden
,
Ashleigh M Stone
,
Nick Osborne
,
Ben Wheeler
,
Louisa Vine
,
Amanda Dickson
,
Maggie Barlow
,
James Lewis
,
Richard P Bendall
,
others
(2016).
Coastal clustering of HEV; Cornwall, UK
.
European Journal of Gastroenterology and Hepatology
.
Cite
McAllister-Williams RH
,
Anderson IM
,
Finkelmeyer A
,
Gallagher P
,
Grunze HCR
,
Haddad PM
,
Hughes T
,
Lloyd AJ
,
Mamasoula C
,
McColl E
,
Pearce S
,
Siddiqi N
,
Sinha BNP
,
Steen N
,
Wainwright J
,
Winter FH
,
Ferrier IN
,
Watson S
(2015).
Antidepressant augmentation with metyrapone for treatment-resistant depression (the ADD study): A double-blind, randomised, placebo-controlled trial
.
Lancet Psychiat
2016; 3:117-27.
DOI
Heasman PA
,
Holliday R
,
Bryant A
,
Preshaw PM
(2015).
Evidence for the occurrence of gingival recession and non-carious cervical lesions as a consequence of traumatic toothbrushing
.
J Clin Periodontol
2015; 42:S237-55.
DOI
Neely J
,
Miklowitz D
,
Le Couteur A
,
Ryan V
,
Vale L
,
McGovern R
,
Sharma A
(2015).
A feasibility study of a Family Focused Treatment for Adolescents with Bipolar Disorder — The FAB study
.
Pilot Feas Studies
2015; 1:43.
DOI
Wilkins A
,
Mossop H
,
Syndikus I
,
Khoo V
,
Bloomfield D
,
Parker C
,
Logue J
,
Scrase C
,
Patterson H
,
Birtle A
,
Staffurth J
,
Malik Z
,
Panades M
,
Eswar C
,
Graham J
,
Russell M
,
Kirkbride P
,
O'Sullivan JM
,
Gao A
,
Cruickshank C
,
Griffin C
,
Dearnaley D
,
Hall E
(2015).
Hypofractionated radiotherapy versus conventionally fractionated radiotherapy for patients with intermediate-risk localised prostate cancer: 2-year patient-reported outcomes of the randomised, non-inferiority, phase 3 CHHiP trial
.
Lancet Oncol
2015; 16:1605-16.
DOI
Cumberbatch MG
,
Cox A
,
Teare D
,
Catto JW
(2015).
Contemporary occupational carcinogen exposure and bladder cancer: A systematic review and meta-analysis
.
JAMA Oncol
2015; 1:1282-90.
DOI
Hoo ZH
,
Daniels T
,
Wildman MJ
,
Teare MD
,
Bradley JM
(2015).
Airway clearance techniques used by people with cystic fibrosis in the UK
.
Physiotherapy
2015; 101:340-8.
DOI
Kuczawski M
,
Mason S
,
Teare M
,
Stevenson M
,
Goodacre S
,
Holmes M
,
Harper R
,
Ramlakhan S
,
Morris F
(2015).
Delayed bleeding in anticoagulated patients after blunt head trauma
.
Emerg Med J
2015; 32:978.
DOI
Cole M
,
Stocken D
,
Yap C
(2015).
A pragmatic approach to the design and calibration of a Bayesian CRM dose finding trial
.
Trials
2015; 16(S2):P210.
DOI
Herriott A
,
Tudhope SJ
,
Junge G
,
Rodrigues N
,
Patterson MJ
,
Woodhouse L
,
Lunec J
,
Hunter JE
,
Mulligan EA
,
Cole M
,
Allinson LM
,
Wallis JP
,
Marshall S
,
Wang E
,
Curtin NJ
,
Willmore E
(2015).
PARP1 expression, activity and ex vivo sensitivity to the PARP inhibitor, talazoparib (BMN 673), in chronic lymphocytic leukaemia
.
Oncotarget
2015; 6:43978-91.
DOI
Fonagy P
,
Butler S
,
Baruch G
,
Byford S
,
Seto MC
,
Wason J
,
Wells C
,
Greisbach J
,
Ellison R
,
Simes E
(2015).
Evaluation of multisystemic therapy pilot services in Services for Teens Engaging in Problem Sexual Behaviour (STEPS-B): Study protocol for a randomized controlled trial
.
Trials
2015; 16:492.
DOI
Huang R
,
Wei Y
,
Hung RJ
,
Liu G
,
Su L
,
Zhang R
,
Zong X
,
Zhang Z-F
,
Morgenstern H
,
Bruske I
,
Heinrich J
,
Hong Y-C
,
Kim JH
,
Cote M
,
Wenzlaff A
,
Schwartz AG
,
Stucker I
,
McLaughlin J
,
Marcus MW
,
Davies MPA
,
Liloglou T
,
Field JK
,
Matsuo K
,
Barnett M
,
Thornquist M
,
Goodman G
,
Wang Y
,
Chen S
,
Yang P
,
Duell EJ
,
Andrew AS
,
Lazarus P
,
Muscat J
,
Woll P
,
Horsman J
,
Teare MD
,
Flugelman A
,
Rennert G
,
Zhang Y
,
Brenner H
,
Stegmaier C
,
van der Heijden EHFM
,
Aben K
,
Kiemeney L
,
Barros-Dios J
,
Pérez-Ríos M
,
Ruano-Ravina A
,
Caporaso NE
,
Bertazzi PA
,
Landi MT
,
Dai J
,
Shen H
,
Fernandez-Tardon G
,
Rodriguez-Suarez M
,
Tardon A
,
Christiani DC
(2015).
Associated links among smoking, chronic obstructive pulmonary disease, and small cell lung cancer: A pooled analysis in the International Lung Cancer Consortium
.
EBioMedicine
2015; __2:__1677-85.
DOI
Mateo J
,
Carreira S
,
Sandhu S
,
Miranda S
,
Mossop H
,
Perez-Lopez R
,
Nava Rodrigues D
,
Robinson D
,
Omlin A
,
Tunariu N
,
Boysen G
,
Porta N
,
Flohr P
,
Gillman A
,
Figueiredo I
,
Paulding C
,
Seed G
,
Jain S
,
Ralph C
,
Protheroe A
,
Hussain S
,
Jones R
,
Elliott T
,
McGovern U
,
Bianchini D
,
Goodall J
,
Zafeiriou Z
,
Williamson CT
,
Ferraldeschi R
,
Riisnaes R
,
Ebbs B
,
Fowler G
,
Roda D
,
Yuan W
,
Wu Y-M
,
Cao X
,
Brough R
,
Pemberton H
,
A'Hern R
,
Swain A
,
Kunju LP
,
Eeles R
,
Attard G
,
Lord CJ
,
Ashworth A
,
Rubin MA
,
Knudsen KE
,
Feng FY
,
Chinnaiyan AM
,
Hall E
,
de Bono JS
(2015).
DNA-repair defects and olaparib in metastatic prostate cancer
.
New Engl J Med
2015; 373:1697-708.
DOI
Litchfield K
,
Holroyd A
,
Lloyd A
,
Broderick P
,
Nsengimana J
,
Eeles R
,
Easton DF
,
Dudakia D
,
Bishop DT
,
Reid A
,
Huddart RA
,
Grotmol T
,
Wiklund F
,
Shipley J
,
Houlston RS
,
Turnbull C
(2015).
Identification of four new susceptibility loci for testicular germ cell tumour
.
Nat Commun
2015; 6:.
DOI
Majid A
,
Bae O-K
,
Redgrave J
,
Teare D
,
Ali A
,
Zemke D
(2015).
The potential of adaptive design in animal studies
.
Int J Mol Sci
2015; 16:24048–58.
DOI
Gerety EL
,
Lawrence EM
,
Wason J
,
Yan H
,
Hilborne S
,
Buscombe J
,
Cheow HK
,
Shaw AS
,
Bird N
,
Fife K
,
Heard S
,
Lomas DJ
,
Matakidou A
,
Soloviev D
,
Eisen T
,
Gallagher FA
(2015).
Prospective study evaluating the relative sensitivity of 18F-NaF PET/CT for detecting skeletal metastases from renal cell carcinoma in comparison to multidetector CT and 99mTc-MDP bone scintigraphy, using an adaptive trial design
.
Ann Oncol
2015; 26:2113-8.
DOI
Williams TA
,
Heaps SE
,
Cherlin S
,
Nye TMW
,
Boys RJ
,
Embley TM
(2015).
New substitution models for rooting phylogenetic trees
.
Philos T Roy Soc B
2015; 370:20140336.
DOI
Ainsworth HF
,
Shin S-Y
,
Cordell HJ
(2015).
A comparison of methods for inferring causal relationships between genotype and phenotype using multi‐omics data
.
Genet Epidemiol
2015; 39:529-99.
DOI
Hilton P
,
Armstrong N
,
Brennand C
,
Howel D
,
Shen J
,
Bryant A
,
Tincello DG
,
Lucas MG
,
Buckley BS
,
Chapple CR
,
Homer T
,
Vale L
,
McColl E
,
INVESTIGATE Studies Group
(2015).
A mixed methods study to assess the feasibility of a randomised controlled trial of invasive urodynamic testing versus clinical assessment and non-invasive tests prior to surgery for stress urinary incontinence in women: The INVESTIGATE-I study
.
Trials
2015; 16:400.
DOI
Gao L
,
van den Hurk K
,
Nsengimana J
,
Laye JP
,
van den Oord JJ
,
Beck S
,
Gruis NA
,
Zoutman WH
,
van Engeland M
,
Newton-Bishop JA
,
Winnepenninckx VJ
,
van Doorn R
(2015).
Prognostic significance of promoter hypermethylation and diminished gene expression of SYNPO2 in melanoma
.
J Invest Dermatol
2015; 135:2328-31.
DOI
Frost JA
,
Webster KE
,
Bryant A
,
Morrison, J
(2015).
Lymphadenectomy for the management of endometrial cancer
.
Cochrane Database Syst Rev
2015; 9:CD007585.
DOI
Howey R
,
Mamasoula C
,
Töpf A
,
Nudel R
,
Goodship JA
,
Keavney BD
,
Cordell HJ
(2015).
Increased power for detection of parent-of-origin effects via the use of haplotype estimation
.
Am J Hum Genet
2015; 97:419-34.
DOI
Wason JMS
(2015).
OptGS: An R package for finding near-optimal group-sequential designs
.
J Stat Soft
2015; 66:1-13.
DOI
Luo M
,
Zheng H-Y
,
Zhang Y
,
Feng Y
,
Li D-Q
,
Li X-L
,
Han J-F
,
Li T-P
(2015).
A nomogram for predicting the likelihood of obstructive sleep apnea to reduce the unnecessary polysomnography examinations
.
Chin Med J (Engl)
2015; 128:2134-40.
Wason JMS
,
Abraham J
,
Baird R
,
Gournaris I
,
Vallier A-L
,
Brenton J
,
Earl H
,
Mander A
(2015).
A Bayesian adaptive design for biomarker trials with linked treatments
.
Br J Cancer
2015; 113:699-705.
DOI
Brass D
,
Farr P
,
Reynolds N
,
Stocken D
,
MacDonald C
,
Wahie S
,
Weatherhead S
,
Wilkinson J
,
Lloyd J
,
Hill S
,
Fouweather T
,
Hampton P
(2015).
An observer-blinded randomized controlled pilotstudy comparing localised psoralen–ultraviolet A with localized narrowband ultraviolet B for thetreatment of hand eczema
.
Brit J Dermatol
2015; 173:11-3.
DOI
Wason J
(2015).
Multi-Arm Multi-Stage Designs for Clinical Trials with Treatment Selection
. In
Modern Adaptive Randomized Clinical Trials: Statistical and Practical Aspects
.
Newbury-Birch D
,
Jackson K
,
Hodgson T
,
Gilvarry E
,
Cassidy P
,
Coulton S
,
Ryan V
,
Wilson GB
,
McGovern R
,
Kaner E
(2015).
Alcohol-related risk and harm amongst young offenders aged 11-17
.
Int J Prisoner Health
2015; 11:75-86.
DOI
Tan MP
,
Murray A
,
Hawkins T
,
Chadwick TJ
,
Kerr SRJ
,
Parry SW
(2015).
Cardiac Iodine-123-Meta-Iodo-Benzylguanidine uptake in carotid sinus hypersensitivity
.
PLoS ONE
2015; 10:e0126241.
DOI
Tada S
,
Allen PF
,
Ikebe K
,
Zheng H
,
Shintani A
,
Maeda Y
(2015).
The impact of the crown-root ratio on survival of abutment teeth for dentures
.
J Dent Res
2015; 94:220S-5.
DOI
Kunz CU
,
Wason JMS
,
Meinhard Kieser
(2015).
Two-stage phase II oncology designs using short-term endpoints for early stopping
.
Stat Methods Med Res
2017; 26:1671-83.
DOI
Villar S
,
Wason J
,
Bowden J
(2015).
Response‐adaptive randomization for multi‐arm clinical trials using the forward looking Gittins index rule
.
Biometrics
2015; 71:969-78.
DOI
Nikolic MZ
,
Lok LSC
,
Mattishent K
,
Barth S
,
Yung B
,
Cummings NM
,
Wade D
,
Vali Y
,
Chong K
,
Wilkinson A
,
Mikolasch T
,
Brij S
,
Jenkins HS
,
Kamath AV
,
Pasteur M
,
Hopkins TG
,
Wason J
,
Marciniak SJ
(2015).
Noninterventional statistical comparison of BTS and CHEST guidelines for size and severity in primary pneumothorax
.
Eur Respir J
2015; 45:1731–4.
DOI
Wason JMS
,
Jaki T
(2015).
A review of statistical designs for improving the efficiency of phase II studies in oncology
.
Stat Meth Med Res
2016; 25:1010-21.
DOI
Thomas K
,
Wright SE
,
Watson G
,
Baker C
,
Stafford V
,
Wade C
,
Chadwick TJ
,
Mansfield L
,
Wilkinson J
,
Shen J
,
Deverill M
,
Bonner S
,
Hugill K
,
Howard P
,
Henderson A
,
Roy A
,
Furneval J
,
Baudouin SV
(2015).
Extra Physiotherapy in Critical Care (EPICC) trial protocol: A randomised controlled trial of intensive versus standard physical rehabilitation therapy in the critically ill
.
BMJ Open
2015; 5:e008035.
DOI
Masca NGD
,
Hensor EMA
,
Cornelius VR
,
Buffa FM
,
Marriott HM
,
Eales JM
,
Messenger MP
,
Anderson AE
,
Boot C
,
Bunce C
,
Goldin RD
,
Harris J
,
Hinchliffe RF
,
Junaid H
,
Kingston S
,
Martin-Ruiz C
,
Nelson CP
,
Peacock J
,
Seed PT
,
Shinkins B
,
Staples KJ
,
Toombs J
,
Wright AKA
,
Teare MD
(2015).
RIPOSTE: A framework for improving the design and analysis of laboratory-based research
.
eLife
2015; 4:e05519.
DOI
Verbist B
,
Klambauer G
,
Vervoort L
,
Talloen W
,
Shkedy Z
,
Thas O
,
Bender A
,
Göhlmann HWH
,
Hochreiter S
(2015).
Using transcriptomics to guide lead optimization in drug discovery projects: Lessons learned from the QSTAR project
.
Drug Discov Today
2015; 20:505-13.
DOI
Wason JMS
,
Dentamaro A
,
TG Eisen
(2015).
The power of phase II end-points for different possible mechanisms of action of an experimental treatment
.
Eur J Cancer
2015; 51:984-92.
DOI
Hilton P
,
Bryant A
,
Howel D
,
McColl E
,
Shen J
,
Homer T
,
Vale L
,
Buckley BS
,
Lucas MG
,
Tincello DG
,
Armstrong N
,
INVESTIGATE Studies Group
(2015).
Re: Hilton P, Bryant A, Howel D, McColl E, Buckley BS, Lucas MG, et al. Assessing professional equipoise and views about a future clinical trial of invasive urodynamics prior to surgery for stress urinary incontinence in women: A survey within a mixed methods feasibility study. Neurourol Urodyn. 2012;31(8):1223–30
.
Neurourol Urodynam
2016; 35:750-1.
DOI
Fouweather T
,
Gillies C
,
Wohland P
,
Van Oyen H
,
Nusselder W
,
Robine J-M
,
Cambois E
,
Jagger C
,
for the JA: EHLEIS Team
(2015).
Comparison of socio-economic indicators explaining inequalities in Healthy Life Years at age 50 in Europe: 2005 and 2010
.
Eur J Public Health
2015; 25:978–83.
DOI
Matthews JNS
,
Badi NH
(2015).
Inconsistent treatment estimates from mis‐specified logistic regression analyses of randomized trials
.
Stat Med
2015; 34:2681-94.
DOI
Chen LS
,
Hung RJ
,
Baker T
,
Horton A
,
Culverhouse R
,
Saccone N
,
Cheng I
,
Deng B
,
Han Y
,
Hansen HM
,
Horsman J
,
Kim C
,
Lutz S
,
Rosenberger A
,
Aben KK
,
Andrew AS
,
Breslau N
,
Chang SC
,
Dieffenbach AK
,
Dienemann H
,
Frederiksen B
,
Han J
,
Hatsukami DK
,
Johnson EO
,
Pande M
,
Wrensch MR
,
McLaughlin J
,
Skaug V
,
van der Heijden HF
,
Wampfler J
,
Wenzlaff A
,
Woll P
,
Zienolddiny S
,
Bickeboller H
,
Brenner H
,
Duell EJ
,
Haugen A
,
Heinrich J
,
Hokanson JE
,
Hunter DJ
,
Kiemeney LA
,
Lazarus P
,
Le Marchand L
,
Liu G
,
Mayordomo J
,
Risch A
,
Schwartz AG
,
Teare D
,
Wu X
,
Wiencke JK
,
Yang P
,
Zhang ZF
,
Spitz MR
,
Kraft P
,
Amos CI
,
Bierut LJ
(2015).
CHRNA5 risk variant predicts delayed smoking cessation and earlier lung cancer diagnosis—A meta-analysis
.
JNCI: J Natl Cancer Inst
2015; 107:djv100.
DOI
Kokka F
,
Bryant A
,
Brockbank E
,
Powell M
,
Oram D
(2015).
Hysterectomy with radiotherapy or chemotherapy or both for women with locally advanced cervical cancer
.
Cochrane Database Syst Rev
2015; 4:CD010260.
DOI
Seamus Kent
,
Iryna Schlackow
,
Jingky Lozano-Kühne
,
Christina Reith
,
Jonathan Emberson
,
Richard Haynes
,
Alastair Gray
,
Alan Cass
,
Colin Baigent
,
Martin J Landray
,
William Herrington
,
Borislava Mihaylova and
(2015).
What is the impact of chronic kidney disease stage and cardiovascular disease on the annual cost of hospital care in moderate-to-severe kidney disease?
.
BMC Nephrology
.
Cite
DOI
URL
Ashby-Mitchell K
,
Jagger C
,
Fouweather T
,
Anstey KJ
(2015).
Life expectancy with and without cognitive impairment in seven Latin American and Caribbean countries
.
PLoS ONE
2015; 10:e0121867.
DOI
Nsengimana J
,
Laye J
,
Filia A
,
Walker C
,
Jewell R
,
van den Oord JJ
,
Wolter P
,
Patel P
,
Sucker A
,
Schadendorf D
,
Jönsson GB
,
Bishop DT
,
Newton-Bishop J
(2015).
Independent replication of a melanoma subtype gene signature and evaluation of its prognostic value and biological correlates in a population cohort
.
Oncotarget
2015; 6:11683-93.
DOI
Corris P
,
Ryan VA
,
Small T
,
Lordan J
,
Fisher AJ
,
Meachery G
,
Johnson G
,
Ward C
(2015).
A randomised controlled trial of azithromycin therapy in bronchiolitis obliterans syndrome (BOS) post lung transplantation
.
Thorax
2015; 70:442-50.
DOI
Zhang LR
,
Morgenstern H
,
Greenland S
,
Chang S-C
,
Lazarus P
,
Teare MD
,
Woll PJ
,
Orlow I
,
Cox B
,
Cannabis and Respiratory Disease Research Group of New Zealand
,
Brhane Y
,
Liu G
,
Hung RJ
(2015).
Cannabis smoking and lung cancer risk: Pooled analysis in the International Lung Cancer Consortium
.
Int J Cancer
2015; 136:894-903.
DOI
Hilton P
,
Armstrong N
,
Brennand C
,
Howel D
,
Shen J
,
Bryant A
,
Tincello DG
,
Lucas MG
,
Buckley BS
,
Chapple CR
,
Homer T
,
Vale L
,
McColl E
(2015).
INVESTIGATE-I (INVasive Evaluation before Surgical Treatment of Incontinence Gives Added Therapeutic Effect?): A mixed-methods study to assess the feasibility of a future randomised controlled trial of invasive urodynamic testing prior to surgery for stress urinary incontinence in women
.
Health Technol Assess
2015; 19(15).
DOI
Hearne BJ
,
Teare MD
,
Butt M
,
Donaldson L
(2015).
Comparison of Nottingham Prognostic Index and Adjuvant Online prognostic tools in young women with breast cancer: Review of a single-institution experience
.
BMJ Open
2015; 5:e005576.
DOI
Spence S
,
White M
,
Adamson AJ
,
Matthews JNS
(2015).
Does the use of passive or active consent affect consent or completion rates, or dietary data quality? Repeat cross-sectional survey among school children aged 11-12 years
.
BMJ Open
2015; 5:e006457.
DOI
Smits A
,
Bryant A
,
Lopes AD
,
Galaal K
(2015).
Lymph node dissection (lymphadenectomy) for presumed early stage epithelial ovarian cancer
.
Cochrane Database Syst Rev
2015; 1:CD011453.
DOI
van der Heijden E
,
Lopes AD
,
Bryant A
,
Bekkers R
,
Galaal K
(2015).
Follow-up strategies after treatment (large loop excision of the transformation zone (LLETZ)) for cervical intraepithelial neoplasia (CIN): Impact of human papillomavirus (HPV) test
.
Cochrane Db Syst Rev
2015; 1:CD010757.
DOI
Berger N
,
Van Oyen H
,
Cambois E
,
Fouweather T
,
Jagger C
,
Nusselder W
,
Robine J-M
(2015).
Assessing the validity of the Global Activity Limitation Indicator in fourteen European countries
.
BMC Med Res Methodol
2015; 15:1.
DOI
Villar SS
,
Bowden J
,
Wason J
(2015).
Multi-armed bandit models for the optimal design of clinical trials: benefits and challenges
.
Stat Sci
2015; 30:199-215.
DOI
Celis-Morales C
,
Livingstone KM
,
Marsaux CFM
,
Forster H
,
O'Donovan CB
,
Woolhead C
,
Macready AL
,
Fallaize R
,
Navas-Carretero S
,
San-Cristobal R
,
Kolossa S
,
Hartwig K
,
Tsirigoti L
,
Lambrinou CP
,
Moschonis G
,
Godlewska M
,
Surwiłło A
,
Grimaldi K
,
Bouwman J
,
Daly EJ
,
Akujobi V
,
O'Riordan R
,
Hoonhout J
,
Claassen A
,
Hoeller U
,
Gundersen TE
,
Kaland SE
,
Matthews JNS
,
Manios Y
,
Traczyk I
,
Drevon CA
,
Gibney ER
,
Brennan L
,
Walsh MC
,
Lovegrove JA
,
Martinez JA
,
Saris WHM
,
Daniel H
,
Gibney M
,
Mathers JC
(2014).
Design and baseline characteristics of the Food4Me study: A web-based randomised controlled trial of personalised nutrition in seven European countries
.
Genes Nutr
2014; 10:450.
DOI
Little SA
,
Leelarathna L
,
Walkinshaw E
,
Tan HK
,
Chapple O
,
Lubina-Solomon A
,
Chadwick TJ
,
Barendse S
,
Stocken DD
,
Brennand C
,
Marshall SM
,
Wood R
,
Speight J
,
Kerr D
,
Flanagan D
,
Heller SR
,
Evans ML
,
Shaw JAM
(2014).
Response to comment on Little et al. Recovery of hypoglycemia awareness in long-standing type 1 diabetes: A multicenter 2 × 2 factorial randomized controlled trial comparing insulin pump with multiple daily injections and continuous with conventional glucose self-monitoring (HypoCOMPaSS). Diabetes Care 2014;37:2114-2122
.
Diabetes Care
2014; 37:e272-3.
DOI
Grayling MJ
(2014).
phaseR: An R package for phase plane analysis of autonomous ODE systems
.
R J
2014; 6:43-51.
Code
DOI
.bib
.enw
.ris
Law LM
,
Wason JMS
(2014).
Design of telehealth trials – Introducing adaptive approaches
.
Int J Med Inform
2014; 83:870-80.
DOI
Spence S
,
Delve J
,
Stamp E
,
Matthews JNS
,
White M
,
Adamson AJ
(2014).
Did school food and nutrient-based standards in England impact on 11–12y olds nutrient intake at lunchtime and in total diet? Repeat cross-sectional study
.
PLoS ONE
2014; 9:e112648.
DOI
Litchfield K
,
Sultana R
,
Renwick A
,
Dudakia D
,
Seal S
,
Ramsay E
,
Powell S
,
Elliott A
,
Warren-Perry M
,
Peto J
,
Kote-Jarai Z
,
Muir K
,
Nsengimana J
,
Stratton MR
,
Bishop DT
,
Huddart RA
,
Rahman N
,
Turnbull C
,
Pugh J
,
Linger R
,
Marke J
,
Hughes D
,
Pernet D
,
Hall P
,
Berchuck A
,
Eeles R
,
Chenevix-Trench G
,
Dennis J
,
Dunning AM
,
Lee A
,
Dicks E
,
Easton DF
,
Benitez J
,
Gonzalez-Neira A
,
Simard J
,
Tessier DC
,
Bacot F
,
Vincent D
,
LaBoissiere S
,
Robidoux F
,
Bojesen SE
,
Nielsen SF
,
Nordestgaard BG
,
Cunningham JM
,
Windebank SA
,
Hilker CA
,
Meyer J
(2014).
Multi-stage genome-wide association study identifies new susceptibility locus for testicular germ cell tumour on chromosome 3q25
.
Hum Mol Genet
2014; 24:1169-76.
DOI
Wigham S
,
Ternent L
,
Bryant A
,
Robalino S
,
Sniehotta FF
,
Adams J
(2014).
Parental financial incentives for increasing preschool vaccination uptake: Systematic review
.
Pediatrics
2014; 134:e1117-28.
DOI
Fiddes B
,
Wason J
,
Sawcer S
(2014).
Confounding in association studies: Month of birth and multiple sclerosis
.
J Neurol
2014; 261(10):1851-6.
DOI
Fordham SE
,
Cole M
,
Irving JA
,
Allan JM
(2014).
Abstract 5457: Cytarabine leaves a mutational fingerprint in relapsing leukemia
.
Cancer Res
2014; 74:5457.
DOI
Veal GJ
,
Hill CR
,
Cole M
,
Errington J
,
Malik G
,
Boddy AV
(2014).
Abstract 4651: Characterization of the clinical pharmacokinetics of actinomycin D and the influence of pharmacogenetic variation in children with cancer
.
Cancer Res
2014; 74:4651.
DOI
Fordham SE
,
Cole M
,
Irving JA
,
Allan JM
(2014).
Cytarabine preferentially induces mutation at specific sequences in the genome which are identifiable in relapsed acute myeloid leukaemia
.
Leukemia
2015; 29:491-4.
DOI
Wason J
,
Stallard N
,
Bowden J
,
Jennison C
(2014).
A multi-stage drop-the-losers design for multi-arm clinical trials
.
Stat Meth Med Res
2017; 26:508-24.
DOI
Jewell R
,
Elliott F
,
Laye J
,
Nsengimana J
,
Davies J
,
Walker C
,
Conway C
,
Mitra A
,
Harland M
,
Cook MG
,
Boon A
,
Storr S
,
Safuan S
,
Martin SG
,
Jirström K
,
Olsson H
,
Ingvar C
,
Lauss M
,
Bishop T
,
Jönsson G
,
Newton-Bishop J
(2014).
The clinicopathological and gene expression patterns associated with ulceration of primary melanoma
.
Pigm Cell Melanoma R
2014; 28:94-104.
DOI
Wason JMS
(2014).
Recent Developments in Group-Sequential Designs
. In
Developments in Statistical Evaluation of Clinical Trials
2014; 97-118.
DOI
Clarke T
,
Galaal K
,
Bryant A
,
Naik R
(2014).
Evaluation of follow‐up strategies for patients with epithelial ovarian cancer following completion of primary treatment
.
Cochrane Database Syst Rev
2014; 9:CD006119.
DOI
Wason JMS
,
Stecher L
,
Mander AP
(2014).
Correcting for multiple-testing in multi-arm trials: Is it necessary and is it done?
.
Trials
2014; 15:364.
DOI
Teare MD
,
Santibáñez Koref MF
(2014).
Linkage analysis and the study of Mendelian disease in the era of whole exome and genome sequencing
.
Briefn Funct Genomics
2014; 13:378-83.
DOI
Lawrie TA
,
Patel A
,
Martin‐Hirsch PPL
,
Bryant A
,
Ratnavelu NDG
,
Naik R
,
Ralte A
(2014).
Sentinel node assessment for diagnosis of groin lymph node involvement in vulval cancer
.
Cochrane Database Syst Rev
2014; 6:CD010409.
DOI
Rowe R
,
Parviz Y
,
Iqbal J
,
Heppenstall J
,
Teare D
,
Gunn J
(2014).
Repeat coronary angiography with previously normal arteries: A futile exercise?
.
Catheter Cardiovasc Interv
2015; 85:401-5.
DOI
Hill CR
,
Cole M
,
Errington J
,
Malik G
,
Boddy AV
,
Veal GJ
(2014).
Characterisation of the clinical pharmacokinetics of actinomycin D and the influence of ABCB1 pharmacogenetic variation on actinomycin D disposition in children with cancer
.
Clin Pharmacokinet
2014; 53:741-51.
DOI
Martin RIR
,
Pogoryelova O
,
Santibanez Koref M
,
Bourke JP
,
Teare MD
,
Keavney BD
(2014).
Atrial fibrillation associated with ivabradine treatment: meta-analysis of randomised controlled trials
.
Heart
2014; 100:1506-1510.
DOI
Tan MP
,
Chadwick TJ
,
Kerr SRJ
,
Parry SW
(2014).
Symptomatic presentation of carotid sinus hypersensitivity is associated with impaired cerebral autoregulation
.
J Am Heart Assoc
2014; 3:e000514.
DOI
Kokka F
,
Bryant A
,
Brockbank E
,
Jeyarajah A
(2014).
Surgical treatment of stage IA2 cervical cancer
.
Cochrane Database Syst Rev
2014; 5:CD010870.
DOI
Little SA
,
Leelarathna L
,
Walkinshaw E
,
Tan HK
,
Chapple O
,
Lubina-Solomon A
,
Chadwick TJ
,
Barendse S
,
Stocken DD
,
Brennand C
,
Marshall SM
,
Wood R
,
Speight J
,
Kerr D
,
Flanagan D
,
Heller SR
,
Evans ML
,
Shaw JAM
(2014).
Recovery of hypoglycemia awareness in long-standing type 1 diabetes: A multicenter 2 x 2 factorial randomized controlled trial comparing insulin pump with multiple daily injections and continuous with conventional glucose self-monitoring (HypoCOMPaSS)
.
Diabetes Care
2014; 37:2114-22.
DOI
Hoo ZH
,
Wildman MJ
,
Teare MD
(2014).
Exploration of the impact of ‘mild phenotypes' on median age at death in the U.K. CF registry
.
Respir Med
2014; 108:716-21.
DOI
Abbotts R
,
Jewell R
,
Nsengimana J
,
Maloney DJ
,
Simeonov A
,
Seedhouse C
,
Elliott F
,
Laye J
,
Walker C
,
Jadhav A
,
Grabowska A
,
Ball G
,
Patel PM
,
Newton-Bishop J
,
Wilson DM
,
Madhusudan S
(2014).
Targeting human apurinic/apyrimidinic endonuclease 1 (APE1) in phosphatase and tensin homolog (PTEN) deficient melanoma cells for personalized therapy
.
Oncotarget
2014; 5:3274-86.
DOI
Bryant A
,
Gurumurthy M
,
Shanbhag S
(2014).
Effectiveness of different treatment modalities for the management of adult‐onset granulosa cell tumours of the ovary (primary and recurrent)
.
Cochrane Database Syst Rev
2014; 4:CD006912.
DOI
Fiddes B
,
Wason J
,
Sawcer SJ
(2014).
Comment on: Month of birth and risk of multiple sclerosis: Confounding and adjustments
.
Ann Clin Transl Neurol
2014; 1:375.
DOI
Wason J
,
Marshall A
,
Dunn J
,
Stein RC
,
Stallard N
(2014).
Adaptive designs for clinical trials assessing biomarker-guided treatment strategies.
.
Br J Cancer
2014; 110:1950-7.
DOI
Ang C
,
Bryant A
,
Barton DPJ
,
Pomel C
,
Naik R
(2014).
Exenterative surgery for recurrent gynaecological malignancies
.
Cochrane Database Syst Rev
2014; 2:CD010449.
DOI
Taylor LH
,
Wilson AG
,
Teare MD
(2014).
AB0019 A PLS multivariate model to predict RA radiological severity by selecting key predictors from a large panel of SNPS and environmental factors
.
Ann Rheum Dis
2013; 71(Suppl 3):638.
DOI
Wason JMS
,
Trippa L
(2014).
A comparison of Bayesian adaptive randomization and multi-stage designs for multi-arm clinical trials
.
Stat Med
2014; 33:2206-21.
DOI
Michael O Baclig
,
Jingky P Lozano-K"uhne
,
Cynthia A Mapua
,
Juliet Gopez-Cervantes
,
Filipinas F Natividad
,
The St Luke’s Liver Diseases
,
Study Group
(2014).
Genetic variation I148M in patatin-like phospholipase 3 gene and risk of non-alcoholic fatty liver disease among Filipinos
.
International Journal of Clinical and Experimental Medicine
.
Cite
Coulthard MG
,
Lambert HJ
,
Vernon SJ
,
Hunter EW
,
Keir MJ
,
Matthews JNS
(2013).
Does prompt treatment of urinary tract infection in preschool children prevent renal scarring: Mixed retrospective and prospective audits
.
Arch Dis Child
2013; 99:342-7.
DOI
Spence S
,
Matthews JNS
,
White M
,
Adamson AJ
(2013).
Did legislation to regulate school meals in England widen dietary inequalities in children aged 4–7 years? A repeat cross-sectional study
.
Lancet
2013; 382:S91.
DOI
Lanceley A
,
Fiander A
,
McCormack M
,
Bryant A
(2013).
Follow‐up protocols for women with cervical cancer after primary treatment
.
Cochrane Database Syst Rev
2013; 11:CD008767.
DOI
Nama V
,
Nordin A
,
Bryant A
(2013).
Patient‐reported outcome measures for follow‐up after gynaecological cancer treatment
.
Cochrane Database Syst Rev
2013; 11:CD010299.
DOI
Leelarathna L
,
Little SA
,
Walkinshaw E
,
Tan HK
,
Lubina-Solomon A
,
Kumareswaran K
,
Lane AP
,
Chadwick T
,
Marshall SM
,
Speight J
,
Flanagan D
,
Heller SR
,
Shaw JAM
,
Evans ML
(2013).
Restoration of self-awareness of hypoglycemia in adults with long-standing type 1 diabetes
.
Diabetes Care
2013; 36:4063-70.
DOI
Penn L
,
Ryan V
,
White M
(2013).
Feasibility, acceptability and outcomes at a 12-month follow-up of a novel community-based intervention to prevent type 2 diabetes in adults at high risk: Mixed methods pilot study
.
BMJ Open
2013; 3:e003585.
DOI
Howel D
,
Stamp E
,
Chadwick TJ
,
Adamson AJ
,
White M
(2013).
Are social inequalities widening in generalised and abdominal obesity and overweight among English adults?
.
PLoS ONE
2013; 8:e79027.
DOI
Wason JMS
(2013).
Reducing the average number of patients needed in a phase II trial through novel design
.
Clin Res Regul Aff
2013; 30(4):47-54.
DOI
Nan Xuan Lin
,
Stuart Logan
,
William Edward Henley
(2013).
Bias and Sensitivity Analysis When Estimating Treatment Effects from the Cox Model with Omitted Covariates
.
Biometrics
.
Cite
DOI
URL
Taylor F
,
Teare MD
,
Cox A
,
Woll PJ
(2013).
Circulating cell-free DNA: A potential biomarker in lung cancer
.
Lung Cancer Management
2013; 2.
DOI
Kucukmetin A
,
Biliatis I
,
Naik R
,
Bryant A
(2013).
Laparoscopically assisted radical vaginal hysterectomy versus radical abdominal hysterectomy for the treatment of early cervical cancer
.
Cochrane Database Syst Rev
2013; 10:CD006651.
DOI
Schoenmakers I
,
Francis RM
,
McColl E
,
Chadwick T
,
Goldberg GR
,
Harle C
,
Yarnall A
,
Wilkinson J
,
Parker J
,
Prentice A
,
Aspray T
(2013).
Vitamin D supplementation in older people (VDOP): Study protocol for a randomised controlled intervention trial with monthly oral dosing with 12,000 IU, 24,000 IU or 48,000 IU of vitamin D3
.
Trials
2013; 14:299.
DOI
Matthews JNS
(2013).
An optimal multi-period crossover design for an application in paediatric nephrology
.
Statistics in Medicine
2014; 33:857-66.
DOI
Galaal K
,
Al Moundhri M
,
Bryant A
,
Lopes AD
(2013).
Surgery and chemotherapy with or without radiotherapy for disseminated advanced endometrial cancer
.
Cochrane Database Syst Rev
2013; 8:CD010681.
DOI
Dyson J
,
Jaques B
,
Chattopadyhay D
,
Lochan R
,
Graham J
,
Das D
,
Aslam T
,
Patanwala I
,
Gaggar S
,
Cole M
,
Sumpter K
,
Stewart S
,
Rose J
,
Hudson M
,
Manas D
,
Reeves HL
(2013).
Hepatocellular cancer: The impact of obesity, type 2 diabetes and a multidisciplinary team
.
J Hepatol
2014; 60:110-7.
DOI
Fonagy P
,
Butler S
,
Goodyer I
,
Cottrell D
,
Scott S
,
Pilling S
,
Eisler I
,
Fuggle P
,
Kraam A
,
Byford S
,
Wason J
,
Haley R
(2013).
Evaluation of multisystemic therapy pilot services in the Systemic Therapy for At Risk Teens (START) trial: Study protocol for a randomised controlled trial
.
Trials
2013; 14:265.
DOI
Romero-Ortuno R
,
Fouweather T
,
Jagger C
(2013).
Cross-national disparities in sex differences in life expectancy with and without frailty
.
Age Ageing
2014; 43:222–8.
DOI
Romero-Ortuno R
,
Fouweather T
,
Jagger C
(2013).
Disparities in life expectancy in frailty stated between European countries
.
Age Ageing
2013; 42:iii15.
DOI
Mamasoula C
,
Prentice RR
,
Pierscionek T
,
Pangilinan F
,
Mills JL
,
Druschel C
,
Pass K
,
Russell MW
,
Hall D
,
Töpf A
,
Brown DL
,
Zelenika D
,
Bentham J
,
Cosgrove C
,
Bhattacharya S
,
Riveron JG
,
Setchfield K
,
Brook JD
,
Bu'Lock FA
,
Thornborough C
,
Rahman TJ
,
Doza JP
,
Tan HL
,
O'Sullivan J
,
Stuart AG
,
Blue G
,
Winlaw D
,
Postma AV
,
Mulder BJM
,
Zwinderman AH
,
van Engelen K
,
Moorman AFM
,
Rauch A
,
Gewillig M
,
Breckpot J
,
Devriendt K
,
Lathrop GM
,
Farrall M
,
Goodship JA
,
Cordell HJ
,
Brody LC
,
Keavney BD
(2013).
Association between C677T polymorphism of methylene tetrahydrofolate reductase and congenital heart disease
.
Circ: Cardiovasc Gene
2013; 6:347-53.
DOI
Fiddes B
,
Wason J
,
Kemppinen A
,
Ban M
,
Compston A
,
Sawcer S
(2013).
Confounding underlies the apparent month of birth effect in multiple sclerosis
.
Ann Neurol
2013; 73:714–20.
DOI
Taylor LH
,
Twigg S
,
Worthington J
,
Emery P
,
Morgan AW
,
Wilson AG
,
Teare MD
(2013).
Metaanalysis of the association of smoking and PTPN22 R620W genotype on autoantibody status and radiological erosions in rheumatoid arthritis
.
J Rheumatol
2013; 40:1048-53.
DOI
Wason JMS
,
Seaman SR
(2013).
Using continuous data on tumour measurements to improve inference in phase II cancer studies
.
Stat Med
2013; 32:4639-50.
DOI
Cordell HJ
,
Bentham J
,
Töpf A
,
Zelenika D
,
Heath S
,
Mamasoula C
,
Cosgrove C
,
Blue G
,
Granados-Riveron J
,
Setchfield K
,
Thornborough C
,
Breckpot J
,
Soemedi R
,
Martin R
,
Rahman TJ
,
Hall D
,
van Engelen K
,
Moorman AFM
,
Zwinderman AH
,
Barnett P
,
Koopmann TT
,
Adriaens ME
,
Varro A
,
George AL
,
dos Remedios C
,
Bishopric NH
,
Bezzina CR
,
O'Sullivan J
,
Gewillig M
,
Bu'Lock FA
,
Winlaw D
,
Bhattacharya S
,
Devriendt K
,
Brook JD
,
Mulder BJM
,
Mital S
,
Postma AV
,
Lathrop GM
,
Farrall M
,
Goodship JA
,
Keavney BD
(2013).
Genome-wide association study of multiple congenital heart disease phenotypes identifies a susceptibility locus for atrial septal defect at chromosome 4p16
.
Nat Genet
2013; 45:822-4.
DOI
Ruark E
,
Seal S
,
McDonald H
,
Zhang F
,
Elliot A
,
Lau KW
,
Perdeaux E
,
Rapley E
,
Eeles R
,
Peto J
,
Kote-Jarai Z
,
Muir K
,
Nsengimana J
,
Shipley J
,
Bishop DT
,
Stratton MR
,
Easton DF
,
Huddart RA
,
Rahman N
,
Turnbull C
(2013).
Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14
.
Nat Genet
2013; 45:686-9.
DOI
Dalton LE
,
Clarke HJ
,
Knight J
,
Lawson MH
,
Wason J
,
Lomas DA
,
Howat WJ
,
Rintoul RC
,
Rassl DM
,
Marciniak SJ
(2013).
The endoplasmic reticulum stress marker CHOP predicts survival in malignant mesothelioma
.
Br J Cancer
2013; 108:1340-7.
DOI
Wason JMS
,
Jaki T
,
Stallard N
(2013).
Planning multi-arm screening studies within the context of a drug development program.
.
Stat Med
2013; 32:3424-35.
DOI
Wilkes S
,
Pearce S
,
Ryan V
,
Rapley T
,
Ingoe L
,
Razvi S
(2013).
Study of Optimal Replacement of Thyroxine in the ElDerly (SORTED): Protocol for a mixed methods feasibility study to assess the clinical utility of lower dose thyroxine in elderly hypothyroid patients: Study protocol for a randomized controlled trial
.
Trials
2013; 14:83.
DOI
Matthews JNS
,
Henderson R
(2013).
Two-period, two-treatment crossover designs subject to non-ignorable missing data
.
Biostatistics
2013; 14:626-38.
DOI
Ahmad B
,
Ryan V
,
Maziak W
,
Pless-Mulloli T
,
White M
(2013).
The influence of neighbourhood formality status and socio-economic position on self-rated health among adult men and women: A multilevel, cross sectional, population study from Aleppo, Syria
.
BMC Public Health
2013; 13:233.
DOI
Mondick JT
,
Gibiansky L
,
Gastonguay MR
,
Skolnik JM
,
Cole M
,
Veal GJ
,
Boddy AV
,
Adamson PC
,
Barrett JS
(2013).
Population pharmacokinetic investigation of actinomycin-D in children and young adults
.
J Clin Pharmacol
2008; 48:35-42.
DOI
Brugha TS
,
Matthews R
,
Alonso J
,
Vilagut G
,
Fouweather T
,
Bruffaerts R
,
de Girolamo G
,
de Graaf R
,
Haro JM
,
Kovess V
,
Jagger C
(2013).
Gender differences in mental health expectancies in early- and midlife in six European countries
.
Brit J Psychiat
2013; 202:294-300.
DOI
Al Rawahi T
,
Lopes AD
,
Bristow RE
,
Bryant A
,
Elattar A
,
Chattopadhyay S
,
Galaal K
(2013).
Surgical cytoreduction for recurrent epithelial ovarian cancer
.
Cochrane Db Syst Rev
2013; 2:CD008765.
DOI
Shylasree TS
,
Bryant A
,
Athavale R
(2013).
Chemotherapy and/or radiotherapy in combination with surgery for ovarian carcinosarcoma
.
Cochrane Database Syst Rev
2013; 2:CD006246.
DOI
Galaal K
,
van der Heijden E
,
Godfrey K
,
Naik R
,
Kucukmetin A
,
Bryant A
,
Das N
,
Lopes AD
(2013).
Adjuvant radiotherapy and/or chemotherapy after surgery for uterine carcinosarcoma
.
Cochrane Db Syst Rev
2013; 2:CD006812.
DOI
Harper AR
,
Mayosi BM
,
Rodriguez A
,
Rahman T
,
Hall D
,
Mamasoula C
,
Avery PJ
,
Keavney BD
(2013).
Common variation neighbouring micro-RNA 22 is sssociated with increased left ventricular mass
.
PLoS ONE
2013; 8:e55061.
DOI
Tangjitgamol S
,
Manusirivithaya S
,
Laopaiboon M
,
Lumbiganon P
,
Bryant A
(2013).
Interval debulking surgery for advanced epithelial ovarian cancer
.
Cochrane Database Syst Rev
2013; 4:CD006014.
DOI
Cordell HJ
,
Töpf A
,
Mamasoula C
,
Postma AV
,
Bentham J
,
Zelenika D
,
Heath S
,
Blue G
,
Cosgrove C
,
Grandaos Riveron J
,
Darlay R
,
Soemedi R
,
Wilson IJ
,
Ayers KL
,
Rahman TJ
,
Hall D
,
Mulder BJM
,
Zwinderman AH
,
van Engelen K
,
Brook JD
,
Setchfield K
,
Bu'Lock FA
,
Thornborough C
,
O'Sullivan J
,
Stuart AG
,
Parsons J
,
Bhattacharya S
,
Winlaw D
,
Mital S
,
Gewillig M
,
Breckpot J
,
Devriendt K
,
Moorman AFM
,
Rauch A
,
Lathrop GM
,
Keavney BD
,
Goodship JA
(2013).
Genome-wide association study identifies loci on 12q24 and 13q32 associated with tetralogy of fallot
.
Hum Mol Genet
2013; 22:1473-81.
DOI
Jingky Lozano-Kühne
(2013).
SNPedia
.
Encyclopedia of Systems Biology
.
Cite
DOI
URL
Jingky Lozano-Kühne
(2013).
Disease Databases
.
Encyclopedia of Systems Biology
.
Cite
DOI
URL
Jingky Lozano-Kühne
(2013).
Cancer Resources
.
Encyclopedia of Systems Biology
.
Cite
DOI
URL
Teare MD
,
Knevel R
,
Morgan MD
,
Kleszcz A
,
Emery P
,
Moore DJ
,
Conaghan P
,
Huizinga TWJ
,
Morgan AW
,
van der Helm-van Mil AHM
,
Wilson AG
(2013).
Allele-dose association of the C5orf30 rs26232 variant with joint damage in rheumatoid arthritis
.
Arthritis Rheum
2013; 65:2555-61.
DOI
Patwardhan M
,
Pradhan V
,
Taylor LH
,
Thakkar V
,
Kharkar V
,
Khopkar U
,
Ghosh K
,
Gawkrodger DJ
,
Teare MD
,
Weetman AP
,
Kemp EH
(2012).
The angiotensin-converting enzyme gene insertion/deletion polymorphism in Indian patients with vitiligo: A case–control study and meta-analysis
.
Br J Dermatol
2013; 168:1195-204.
DOI
Little S
,
Chadwick T
,
Choudhary P
,
Brennand C
,
Stickland J
,
Barendse S
,
Olateju T
,
Leelarathna L
,
Walkinshaw E
,
Tan HK
,
Marshall SM
,
Thomas RM
,
Heller S
,
Evans M
,
Kerr D
,
Flanagan D
,
Speight J
,
Shaw JAM
(2012).
Comparison of Optimised MDI versus Pumps with or without Sensors in Severe Hypoglycaemia (the Hypo COMPaSS trial)
.
BMC Endocr Disord
2012; 12:33.
DOI
Wason J
,
Magirr D
,
Law M
,
Jaki T
(2012).
Some recommendations for multi-arm multi-stage trials
.
Stat Meth Med Res
2012; 25:716-27.
DOI
Alex Harrison
,
Linda Scobie
,
Claire Crossan
,
Rob Parry
,
Paul Johnston
,
Jon Stratton
,
Steve Dickinson
,
Vic Ellis
,
Jeremy G. Hunter
,
Oliver R. Prescott
,
Richie Madden
,
Nan X. Lin
,
William E. Henley
,
Richard P. Bendall
,
Harry R. Dalton
(2012).
Hepatitis E seroprevalence in recipients of renal transplants or haemodialysis in southwest England: A case-control study
.
Journal of Medical Virology
.
Cite
DOI
URL
Veal GJ
,
Errington J
,
Rowbotham SE
,
Illingworth NA
,
Malik G
,
Cole M
,
Daly AK
,
Pearson ADJ
,
Boddy AV
(2012).
Adaptive dosing approaches to the individualization of 13-cis-retinoic acid (isotretinoin) treatment for children with high-risk neuroblastoma
.
Clin Cancer Res
2013; 19:469-79.
DOI
Gajjar K
,
Martin‐Hirsch PPL
,
Bryant A
(2012).
Pain relief for women with cervical intraepithelial neoplasia undergoing colposcopy treatment
.
Cochrane Database Syst Rev
2012; 10:CD006120.
DOI
Hilton P
,
Bryant A
,
Howel D
,
McColl E
,
Buckley BS
,
Lucas M
,
Tincello DG
,
Armstrong N
(2012).
Assessing professional equipoise and views about a future clinical trial of invasive urodynamics prior to surgery for stress urinary incontinence in women: A survey within a mixed methods feasibility study
.
Neurourol Urodynam
2012; 31:1223-30.
DOI
Patil CG
,
Pricola K
,
Sarmiento JM
,
Garg SK
,
Bryant A
,
Black KL
(2012).
Whole brain radiation therapy (WBRT) alone versus WBRT and radiosurgery for the treatment of brain metastases
.
Cochrane Database Syst Rev
2012; 9:CD006121.
DOI
Galaal K
,
Bryant A
,
Fisher AD
,
Al‐Khaduri M
,
Kew F
,
Lopes AD
(2012).
Laparoscopy versus laparotomy for the management of early stage endometrial cancer
.
Cochrane Database Syst Rev
2012; 9:CD006655.
DOI
Cote ML
,
Liu M
,
Bonassi S
,
Neri M
,
Schwartz AG
,
Christiani DC
,
Spitz MR
,
Muscat JE
,
Rennert G
,
Aben KK
,
Andrew AS
,
Bencko V
,
Bickeboller H
,
Boffetta P
,
Brennan P
,
Brenner H
,
Duell EJ
,
Fabianova E
,
Field JK
,
Foretova L
,
Friis S
,
Harris CC
,
Holcatova I
,
Hong YC
,
Isla D
,
Janout V
,
Kiemeney LA
,
Kiyohara C
,
Lan Q
,
Lazarus P
,
Lissowska J
,
Le Marchand L
,
Mates D
,
Matsuo K
,
Mayordomo JI
,
McLaughlin JR
,
Morgenstern H
,
Mueller H
,
Orlow I
,
Park BJ
,
Pinchev M
,
Raji OY
,
Rennert HS
,
Rudnai P
,
Seow A
,
Stucker I
,
Szeszenia-Dabrowska N
,
Teare MD
,
Tjonnelan A
,
Ugolini D
,
van der Heijden HFM
,
Wichmann E
,
Wiencke JK
,
Woll PJ
,
Yang P
,
Zaridze D
,
Zhang ZF
,
Etzel CL
,
Hung RJ
(2012).
Increased risk of lung cancer in individuals with a family history of the disease: A pooled analysis from the International Lung Cancer Consortium
.
Eur J Cancer
2012; 48:1957-68.
DOI
Ho WK
,
Matthews JNS
,
Henderson R
,
Farewell D
,
Rodgers LR
(2012).
Dropouts in the AB/BA crossover design
.
Stat Med
2012; 31:1675-87.
DOI
Bowden J
,
Wason J
(2012).
Identifying combined design and analysis procedures in two-stage trials with a binary end point
.
Stat Med
2012; 31:3874-84.
DOI
Adams J
,
Halligan J
,
Watson DB
,
Ryan V
,
Penn L
,
Adamson AJ
,
White M
(2012).
The Change4Life convenience store programme to increase retail access to fresh fruit and vegetables: A mixed methods process evaluation
.
PLoS ONE
2012; 7:e39431.
DOI
Nsengimana J
,
Barrett JH
(2012).
Analysis of genetic interactions involving maternal and offspring genotypes at different loci: Power simulation and application to testicular cancer
.
Genet Epidemiol
2012; 36:612-21.
DOI
Wason JMS
,
Mander AP
(2012).
Minimizing the maximum expected sample size in two-stage phase II clinical trials with continuous outcomes
.
J Biopharm Stat
2012; 22:836-52.
DOI
Rogers L
,
Siu SSN
,
Luesley D
,
Bryant A
,
Dickinson HO
(2012).
Radiotherapy and chemoradiation after surgery for early cervical cancer
.
Cochrane Database Syst Rev
2012; 5:CD007583.
DOI
Dexter LJ
,
Teare MD
,
Dexter M
,
Siriwardena AN
,
Read RC
(2012).
Strategies to increase influenza vaccination rates: Outcomes of a nationwide cross-sectional survey of UK general practice
.
BMJ Open
2012; 2:e000851.
DOI
Wason JMS
,
Dudbridge F
(2012).
A General Framework for Two-Stage Analysis of Genome-wide Association Studies and Its Application to Case-Control Studies
.
Am J Hum Genet
2012; 90:P760-73.
DOI
J Hunter
,
R Madden
,
A Stone
,
N Osborne
,
B Wheeler
,
M Barlow
,
R Bendall
,
N Lin
,
W Henley
,
W Gaze
,
H Dalton
(2012).
PMO-161 Hepatitis E (HEV) in South West England. Geographical, environmental and social factors: a case control study
.
Gut
.
Cite
DOI
URL
Teo MTW
,
Snowden H
,
Nsengimana J
,
Harland M
,
Morgan J
,
Carr I
,
Taylor G
,
Barrett J
,
Bishop DT
,
Kiltie AE
(2012).
Germline MRE11 variants predictive of radiotherapy outcomes in bladder cancer by next-generation sequencing
.
Radiother Oncol
2012; 103:S211-2.
DOI
Mamasoula C
,
Pierscionek T
,
Hall D
,
Töpf A
,
Palomino Doza J
,
Rahman T
,
Tan A
,
Bentham J
,
Bhattacharya S
,
Cosgrove C
,
Brook D
,
Granados-Riveron J
,
Bu'Lock FA
,
O'Sullivan J
,
Wren C
,
Goodship JA
,
Cordell HJ
,
Keavney B
(2012).
Aetiological role of folate deficiency in congenital cardiovascular malformation: Evidence from 'mendelian randomisation' and meta-analysis
.
Genet Epidemiol
2012; 36:118-71.
DOI
Corris P
,
Small T
,
Ryan V
,
Lordan J
,
Fisher AJ
,
Meachery G
,
Johnson G
,
Ward C
(2012).
A randomised controlled trial of azithromycin therapy in bronchiolitis obliterans syndrome (BOS) post lung transplantation
.
Am J Resp Crit Care
2012; 185:A5324.
DOI
Matthews JNS
,
Henderson R
,
Farewell DM
,
Ho W-K
,
Rodgers LR
(2012).
Dropout in crossover and longitudinal studies: Is complete case so bad?
.
Stat Meth Med Res
2014; 23:60-73.
DOI
Woo YL
,
Kyrgiou M
,
Bryant A
,
Everett T
,
Dickinson HO
(2012).
Centralisation of services for gynaecological cancers - A Cochrane systematic review
.
Gynecol Oncol
2012; 126:286-90.
DOI
Goodship JA
,
Hall D
,
Töpf A
,
Mamasoula C
,
Griffin H
,
Rahman TJ
,
Glen E
,
Tan H
,
Palomino Doza J
,
Relton CL
,
Bentham J
,
Bhattacharya S
,
Cosgrove C
,
Brook D
,
Granados-Riveron J
,
Bu'Lock FA
,
O'Sullivan J
,
Stuart AG
,
Parsons J
,
Cordell HJ
,
Keavney B
(2012).
A common variant in the PTPN11 gene contributes to the risk of tetralogy of fallot
.
Circ: Cardiovasc Gene
2012; 5:287-92.
DOI
Sawcer S
,
Wason J
(2012).
Risk in complex genetics: "All models are wrong but some are useful"
.
Ann Neurol
2012; 72:502–9.
DOI
R. G. Madden
,
A. Harrison
,
L. Scobie
,
C. Crossan
,
J. G. Hunter
,
R. Parry
,
P. Johnston
,
J. Stratton
,
S. Dickinson
,
R. Bendall
,
V. Ellis
,
N. Lin
,
W. Henley
,
S. Ijaz
,
H. R. Dalton
(2012).
561 HEV IN RENAL TRANSPLANT AND HAEMODIALYSIS PATIENTS
.
Journal of Hepatology
.
Cite
DOI
URL
R. G. Madden
,
J. G. Hunter
,
A. M. Stone
,
C. Thornton
,
M. Barlow
,
J. Lewis
,
R. Bendall
,
N. Lin
,
W. Henley
,
H. R. Dalton
(2012).
148 LOCALLY ACQUIRED HEPATITIS E. GEOGRAPHICAL CLUSTERING AND ENVIRONMENTAL FACTORS: A NESTED CASE CONTROL STUDY
.
Journal of Hepatology
.
Cite
DOI
URL
Wason JMS
,
Mander AP
,
Thompson SG
(2012).
Optimal multistage designs for randomised clinical trials with continuous outcomes
.
Stat Med
2012; 31:301-12.
DOI
Matthews JNS
(2012).
Effect of prior specification on Bayesian design for two-sample comparison of a binary putcome
.
Am Stat
1999; 53:254-6.
DOI
N. X. Lin
,
J. Q. Shi
,
R. Henderson
(2012).
Doubly misspecified models
.
Biometrika
.
Cite
DOI
URL
Mander AP
,
Wason JMS
,
Sweeting MJ
,
Thompson SG
(2012).
Admissible two-stage designs for phase II cancer clinical trials that incorporate the expected sample size under the alternative hypothesis
.
Pharm Stat
2012; 11:91-6.
DOI
Wason JMS
,
Jaki T
(2012).
Optimal design of multi-arm multi-stage trials
.
Stat Med
2012; 31:4269-79.
DOI
Michael O Baclig
,
May R Alvarez
,
Xerxes Morgan R Lozada
,
Cynthia A Mapua
,
Jingky P Lozano-K"uhne
,
Mark Pierre S Dimamay
,
Filipinas F Natividad
,
Juliet Gopez-Cervantes
,
Ronald R Matias
(2012).
Association of glutathione S-transferase T1 and M1 genotypes with chronic liver diseases among Filipinos
.
International journal of molecular epidemiology and genetics
.
Cite
Michael O Baclig
,
Rey Z Predicala
,
Cynthia A Mapua
,
Jingky P Lozano-K"uhne
,
Maria Luisa G Daroy
,
Filipinas F Natividad
,
Francis O Javier
(2012).
Allelic and genotype frequencies of catechol-O-methyltransferase (Val158Met) and CYP2D6* 10 (Pro34Ser) single nucleotide polymorphisms in the Philippines
.
International journal of molecular epidemiology and genetics
.
Cite
Ainsworth HF
,
Unwin J
,
Jamison DL
,
Cordell HJ
(2011).
Investigation of maternal effects, maternal-fetal interactions and parent-of-origin effects (imprinting), using mothers and their offspring
.
Genet Epidemiol
2011; 35:19-45.
DOI
Nsengimana J
,
Bishop DT
(2011).
Design considerations for genetic linkage and association studies
.
Statistical Human Genetics
2012; 237-262.
DOI
Wason JMS
,
Mander AP
(2011).
The choice of test in phase II cancer trials assessing continuous tumour shrinkage when complete responses are expected
.
Stat Meth Med Res
2015; 24:909-19.
DOI
Teare MD
,
Pinyakorn S
,
Heighway J
,
Santibáñez Koref MF
(2011).
Comparing methods for mapping cis acting polymorphisms using allelic expression ratios
.
PLOS ONE
2011; 6:e28636.
DOI
Galaal K
,
Bryant A
,
Deane KHO
,
Al‐Khaduri M
,
Lopes, A D
(2011).
Interventions for reducing anxiety in women undergoing colposcopy
.
Cochrane Database Syst Rev
2011; 12:CD006013.
DOI
Ryan SL
,
Schwalbe EC
,
Cole M
,
Lu Y
,
Lusher ME
,
Megahed H
,
O'Toole K
,
Nicholson SL
,
Bognar L
,
Garami M
,
Hauser P
,
Korshunov A
,
Pfister SM
,
Williamson D
,
Taylor RE
,
Ellison DW
,
Bailey S
,
Clifford SC
(2011).
MYC family amplification and clinical risk-factors interact to predict an extremely poor prognosis in childhood medulloblastoma
.
Acta Neuropathol
2012; 123:501-13.
DOI
Barrett JH
,
Nsengimana J
(2011).
Two-stage analyses of sequence variants in association with quantitative traits
.
BMC Proc
2011; 5:S53.
DOI
Ayers KL
,
Mamasoula C
,
Cordell HJ
(2011).
Penalized-regression-based multimarker genotype analysis of Genetic Analysis Workshop 17 data
.
BMC Proc
2011; 5:S92.
DOI
König IR
,
Nsengimana J
,
Papachristou C
,
Simonson MA
,
Wang K
,
Weisburd JA
(2011).
Multiple testing in high-throughput sequence data: Experiences from Group 8 of Genetic Analysis Workshop 17
.
Genet Epidemiol
2011; 35:S61-6.
DOI
Haldar K
,
Gaitskell K
,
Bryant A
,
Nicum S
,
Kehoe S
,
Morrison, J
(2011).
Epidermal growth factor receptor blockers for the treatment of ovarian cancer
.
Cochrane Database Syst Rev
2011; 10:CD007927.
DOI
Johnson N
,
Bryant A
,
Miles T
,
Hogberg T
,
Cornes P
(2011).
Adjuvant chemotherapy for endometrial cancer after hysterectomy
.
Cochrane Database Syst Rev
2011; 10:CD003175.
DOI
Rimmer Y
,
Chester J
,
Joffe J
,
Stark D
,
Shamash J
,
Powles T
,
White J
,
Wason J
,
Parashar D
,
Armstrong G
,
Mazhar D
,
Williams MV
(2011).
Accelerated BEP: A phase I trial of dose-dense BEP for intermediate and poor prognosis metastatic germ cell tumour
.
Br J Cancer
2011; 105:766-72.
DOI
Chinnaswamy G
,
Errington J
,
Foot A
,
Boddy AV
,
Veal GJ
,
Cole M
(2011).
Pharmacokinetics of high-dose cyclophosphamide and its metabolites in paediatric patients
.
Pediatr Blood Cancer
2011; 57:705-897.
DOI
Elattar A
,
Bryant A
,
Winter‐Roach BA
,
Hatem M
,
Naik R
(2011).
Optimal primary surgical treatment for advanced epithelial ovarian cancer
.
Cochrane Database Syst Rev
2011; 8:CD007565.
DOI
The International Multiple Sclerosis Genetics Consortium & The Wellcome Trust Case Control Consortium 2
,
Sawcer S
,
Hellenthal G
,
Pirinen M
,
Spencer CCA
,
Patsopoulos NA
,
Moutsianas L
,
Dilthey A
,
Su Z
,
Freeman C
,
Hunt SE
,
Edkins S
,
Gray E
,
Booth DR
,
Potter SC
,
Goris A
,
Band G
,
Bang Oturai A
,
Strange A
,
Saarela J
,
Bellenguez C
,
Fontaine B
,
Gillman M
,
Hemmer B
,
Gwilliam R
,
Zipp F
,
Jayakumar A
,
Martin R
,
Leslie S
,
Hawkins S
,
Giannoulatou E
,
D'Alfonso S
,
Blackburn H
,
Martinelli Boneschi F
,
Liddle J
,
Harbo HF
,
Perez ML
,
Spurkland A
,
Waller MJ
,
Mycko MP
,
Ricketts M
,
Comabella M
,
Hammond N
,
Kockum I
,
McCann OT
,
Ban M
,
Whittaker P
,
Kemppinen A
,
Weston P
,
Hawkins C
,
Widaa S
,
Zajicek J
,
Dronov S
,
Robertson N
,
Bumpstead SJ
,
Barcellos LF
,
Ravindrarajah R
,
Abraham R
,
Alfredsson L
,
Ardlie K
,
Aubin C
,
Baker A
,
Baker K
,
Baranzini SE
,
Bergamaschi L
,
Bergamaschi R
,
Bernstein A
,
Berthele A
,
Boggild M
,
Bradfield JP
,
Brassat D
,
Broadley SA
,
Buck D
,
Butzkueven H
,
Capra R
,
Carroll WM
,
Cavalla P
,
Celius EG
,
Cepok S
,
Chiavacci R
,
Clerget-Darpoux F
,
Clysters K
,
Comi G
,
Cossburn M
,
Cournu-Rebeix I
,
Cox MB
,
Cozen W
,
Cree BAC
,
Cross AH
,
Cusi D
,
Daly MJ
,
Davis E
,
de Bakker PIW
,
Debouverie M
,
D'hooghe MB
,
Dixon K
,
Dobosi R
,
Dubois B
,
Ellinghaus D
,
Elovaara I
,
Esposito F
,
Fontenille C
,
Foote S
,
Franke A
,
Galimberti D
,
Ghezzi A
,
Glessner J
,
Gomez R
,
Gout O
,
Graham C
,
Grant SFA
,
Guerini FR
,
Hakonarson H
,
Hall P
,
Hamsten A
,
Hartung H-P
,
Heard RN
,
Heath S
,
Hobart J
,
Hoshi M
,
Infante-Duarte C
,
Ingram G
,
Ingram W
,
Islam T
,
Jagodic M
,
Kabesch M
,
Kermode AG
,
Kilpatrick TJ
,
Kim C
,
Klopp N
,
Koivisto K
,
Larsson M
,
Lathrop M
,
Lechner-Scott JS
,
Leone MA
,
Leppä V
,
Liljedahl U
,
Lima Bomfim I
,
Lincoln R
,
Link J
,
Liu J
,
Lorentzen ÅR
,
Lupoli S
,
Macciardi F
,
Mack T
,
Marriott M
,
Martinelli V
,
Mason D
,
McCauley JL
,
Mentch F
,
Mero I-L
,
Mihalova T
,
Montalban X
,
Mottershead J
,
Myhr K-M
,
Naldi P
,
Ollier W
,
Page A
,
Palotie A
,
Pelletier J
,
Piccio L
,
Pickersgill T
,
F Piehl F
,
Pobywajlo S
,
Quach HL
,
Ramsay PP
,
Reunanen M
,
Reynolds R
,
Rioux JD
,
Rodegher M
,
Roesner S
,
Rubio JP
,
Rückert I-M
,
Salvetti M
,
Salvi E
,
Santaniello A
,
Schaefer CA
,
Schreiber S
,
Schulze C
,
Scott RJ
,
Sellebjerg F
,
Selmaj KW
,
Sexton D
,
Shen L
,
Simms-Acuna B
,
Skidmore S
,
Sleiman PMA
,
Smestad C
,
Solberg Sørensen P
,
Søndergaard HB
,
Stankovich J
,
Strange RC
,
Sulonen A-M
,
Sundqvist E
,
Syvänen A-C
,
Taddeo F
,
Taylor B
,
Blackwell JM
,
Tienari P
,
Bramon E
,
Tourbah A
,
Brown MA
,
Tronczynska E
,
Casas JP
,
Tubridy N
,
Corvin A
,
Vickery J
,
Jankowski J
,
Villoslada P
,
Markus HS
,
Wang K
,
Mathew CG
,
Wason J
,
Palmer CNA
,
Wichmann H-E
,
Plomin R
,
Willoughby E
,
Rautanen A
,
Winkelmann J
,
Wittig M
,
Trembath RC
,
Yaouanq J
,
Viswanathan AC
,
Zhang H
,
Wood NW
,
Zuvich R
,
Deloukas P
,
Langford C
,
Duncanson A
,
Oksenberg JR
,
Pericak-Vance MA
,
Haines JL
,
Olsson T
,
Hillert J
,
Ivinson AJ
,
De Jager PL
,
Peltonen L
,
Stewart GJ
,
Hafler DA
,
Hauser SL
,
McVean G
,
Donnelly P
,
Compston A
(2011).
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
.
Nature
2011; 476:214-9.
DOI
FE Keane
,
M Gompels
,
RP Bendall
,
R Drayton
,
L Jennings
,
J Black
,
G Baragwanath
,
NX Lin
,
WE Henley
,
S-L Ngui
,
S Ijaz
,
HR Dalton
(2011).
Hepatitis E virus coinfection in patients with HIV infection
.
HIV Medicine
.
Cite
DOI
URL
Williams C
,
Bryant A
(2011).
Short versus long duration infusions of paclitaxel for any advanced adenocarcinoma
.
Cochrane Database Syst Rev
2011; 5:CD003911.
DOI
Chinnaswamy G
,
Errington J
,
Foot A
,
Boddy AV
,
Veal GJ
,
Cole M
(2011).
Pharmacokinetics of cyclophosphamide and its metabolites in paediatric patients receiving high-dose myeloablative therapy
.
Eur J Cancer
2011; 47:1556-63.
DOI
Zaremba T
,
Thomas HD
,
Cole M
,
Coulthard SA
,
Plummer ER
,
Curtin NJ
(2011).
Poly(ADP-ribose) polymerase-1 (PARP-1) pharmacogenetics, activity and expression analysis in cancer patients and healthy volunteers
.
Biochem J
2011; 436:671-9.
DOI
Kew F
,
Galaal K
,
Bryant A
,
Naik R
(2011).
Evaluation of follow‐up strategies for patients with epithelial ovarian cancer following completion of primary treatment
.
Cochrane Database Syst Rev
2011; 6:CD006119.
DOI
Martin‐Hirsch PPL
,
Bryant A
,
Keep SL
,
Kitchener HC
,
Lilford R
(2011).
Adjuvant progestagens for endometrial cancer
.
Cochrane Database Syst Rev
2011; 6:CD001040.
DOI
Everett T
,
Bryant A
,
Griffin MF
,
Martin‐Hirsch PPL
,
Forbes CA
,
Jepson RG
(2011).
Interventions targeted at women to encourage the uptake of cervical screening
.
Cochrane Database Syst Rev
2011; 5:CD002834.
DOI
Ang C
,
Chan KKL
,
Bryant A
,
Naik R
,
Dickinson HO
(2011).
Ultra‐radical (extensive) surgery versus standard surgery for the primary cytoreduction of advanced epithelial ovarian cancer
.
Cochrane Database Syst Rev
2011; 4:CD007697.
DOI
Brockbank E
,
Kokka F
,
Bryant A
,
Pomel C
,
Reynolds K
(2011).
Pre‐treatment surgical para‐aortic lymph node assessment in locally advanced cervical cancer
.
Cochrane Database Syst Rev
2011; 4:CD008217.
DOI
Pepas L
,
Kaushik S
,
Bryant A
,
Nordin A
,
Dickinson HO
(2011).
Medical interventions for high grade vulval intraepithelial neoplasia
.
Cochrane Database Syst Rev
2011; 4:CD007924.
DOI
Shylasree TS
,
Bryant A
,
Howells REJ
(2011).
Chemoradiation for advanced primary vulval cancer
.
Cochrane Database Syst Rev
2011; 4:CD003752.
DOI
Hill RM
,
Lindsey JC
,
Megahed H
,
Schwalbe EC
,
Cole M
,
Hogg TL
,
Gilbertson RJ
,
Ellison DW
,
Bailey S
,
Clifford SC
(2011).
Abstract 3442: TP53 mutations in favorable risk WNT subtype medulloblastomas
.
Cancer Res
2011; 71:3442.
DOI
Abdul Razak AR
,
Li L
,
Bryant A
,
Diaz-Padilla I
(2011).
Chemotherapy for malignant germ cell ovarian cancer in adult patients with early stage, advanced and recurrent disease
.
Cochrane Db Syst Rev
2011; 3:CD007584.
DOI
Kaushik S
,
Pepas L
,
Nordin A
,
Bryant A
,
Dickinson HO
(2011).
Surgical interventions for high grade vulval intraepithelial neoplasia
.
Cochrane Database Syst Rev
2011; 1:CD007928.
DOI
Lindsey JC
,
Hill RM
,
Megahed H
,
Lusher ME
,
Schwalbe EC
,
Cole M
,
Hogg TL
,
Gilbertson RJ
,
Ellison DW
,
Bailey S
,
Clifford SC
(2011).
TP53 mutations in favorable-risk wnt/wingless-subtype medulloblastomas
.
J Clin Oncol
2011; 29:e344-6.
DOI
Schwalbe EC
,
Lindsey JC
,
Straughton D
,
Hogg TL
,
Cole M
,
Megahed H
,
Ryan SL
,
Lusher ME
,
Taylor MD
,
Gilbertson RJ
,
Ellison DW
,
Bailey S
,
Clifford SC
(2011).
Rapid diagnosis of medulloblastoma molecular subgroups
.
Clin Cancer Res
2011; 17:1883-94.
DOI
Akl EA
,
Gunukula S
,
Barba M
,
Yosuico VED
,
van Doormaal FF
,
Kuipers S
,
Middeldorp S
,
Dickinson HO
,
Bryant A
,
Schünemann H
(2011).
Parenteral anticoagulation in patients with cancer who have no therapeutic or prophylactic indication for anticoagulation
.
Cochrane Database Syst Rev
2011; 1:CD006652.
DOI
Wason JMS
,
Mander AP
,
Eisen TG
(2011).
Reducing sample sizes in two-stage phase II cancer trials by using continuous tumour shrinkage end-points
.
Eur J Cancer
2011; 47:983-9.
DOI
Bomken S
,
Davies B
,
Chong L
,
Cole M
,
Wood KM
,
McDermott M
,
Tweddle DA
(2011).
Percentage tumor necrosis following chemotherapy in neuroblastoma correlates with MYCN status but not survival
.
Pediatr Hematol Oncol
2011; 28:106-14.
DOI
Bomken S
,
Davies B
,
Chong L
,
Cole M
,
Wood KM
,
McDermott M
,
Tweddle DA
(2011).
Percentage tumor necrosis following chemotherapy in neuroblastoma correlates with MYCN status but not survival
.
Pediatr Hemat Oncol
2011; 28(2):106-114.
DOI
Galaal K
,
Godfrey K
,
Naik R
,
Kucukmetin A
,
Bryant A
(2011).
Adjuvant radiotherapy and/or chemotherapy after surgery for uterine carcinosarcoma
.
Cochrane Database Syst Rev
2011; 1:CD006812.
DOI
Mitra A
,
Conway C
,
Walker C
,
Cook M
,
Powell B
,
Lobo S
,
Chan M
,
Kissin M
,
Layer G
,
Smallwood J
,
Ottensmeier C
,
Stanley P
,
Peach H
,
Chong H
,
Elliott F
,
Iles MM
,
Nsengimana J
,
Barrett JH
,
Bishop DT
,
Newton-Bishop JA
(2010).
Melanoma sentinel node biopsy and prediction models for relapse and overall survival
.
Br J Cancer
2010; 103(8):1229-1236.
DOI
Wason JMS
,
Dudbridge F
(2010).
Comparison of multimarker logistic regression models, with application to a genomewide scan of schizophrenia
.
BMC Genetics
2010; 11:80.
DOI
Tan MP
,
Kenny RAM
,
Chadwick TJ
,
Kerr SRJ
,
Parry SW
(2010).
Carotid sinus hypersensitivity: Disease state or clinical sign of ageing? Insights from a controlled study of autonomic function in symptomatic and asymptomatic subjects
.
Europace
2010; 12:1630-6.
DOI
Jewell R
,
Conway C
,
Mitra A
,
Randerson-Moor J
,
Lobo S
,
Nsengimana J
,
Harland M
,
Marples M
,
Edward S
,
Cook M
,
Powell B
,
Boon A
,
de Kort F
,
Parker KA
,
Cree IA
,
Barrett JH
,
Knowles MA
,
Bishop DT
,
Newton-Bishop J
(2010).
Patterns of expression of DNA repair genes and relapse from melanoma
.
Clin Cancer Res
2010; 16:5211-21.
DOI
Ban M
,
McCauley JL
,
Zuvich R
,
Baker A
,
Bergamaschi L
,
Cox M
,
Kemppinen A
,
D'Alfonso S
,
Guerini FR
,
Lechner-Scott J
,
Dudbridge F
,
Wason J
,
Robertson NP
,
De Jager PL
,
Hafler DA
,
Barcellos LF
,
Ivinson AJ
,
Sexton D
,
Oksenberg JR
,
Hauser SL
,
Pericak-Vance MA
,
Haines J
,
Compston A
,
Sawcer S
(2010).
A non-synonymous SNP within membrane metalloendopeptidase-like 1 (MMEL1) is associated with multiple sclerosis
.
Genes Immun
2010; 11:660-4.
DOI
Turnbull C
,
Rapley EA
,
Seal S
,
Pernet D
,
Renwick A
,
Hughes D
,
Ricketts M
,
Linger R
,
Nsengimana J
,
Deloukas P
,
Huddart RA
,
Bishop DT
,
Easton DF
,
Stratton MR
,
Rahman N
(2010).
Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer
.
Nat Genet
2010; 42:604-7.
DOI
Zaremba T
,
Thomas H
,
Cole M
,
Plummer ER
,
Curtin NJ
(2010).
Doxorubicin-induced suppression of poly(ADP-ribose) polymerase-1 (PARP-1) activity and expression and its implication for PARP inhibitors in clinical trials
.
Cancer Chemoth Pharm
2010; 66:807-12.
DOI
Bennett CE
,
Nsengimana J
,
Bostock JA
,
Cymbalista C
,
Futers TS
,
Knight BL
,
McCormack LJ
,
Prasad UK
,
Riches K
,
Rolton D
,
Scarrott T
,
Barrett JH
,
Carter AM
(2010).
CCAAT/enhancer binding protein α, β and δ gene variants: Associations with obesity related phenotypes in the Leeds Family Study
.
Diabetes Vasc Dis Re
2010; 7:195-203.
DOI
Skinner R
,
Parry A
,
Price L
,
Cole M
,
Craft AW
,
Pearson ADJ
(2010).
Glomerular toxicity persists 10 years after ifosfamide treatment in childhood and is not predictable by age or dose
.
Pediatr Blood Cancer
2010; 54:983-9.
DOI
Israels T
,
Damen CWN
,
Cole M
,
van Geloven N
,
Boddy AV
,
Caron HN
,
Beijnen JH
,
Molyneux EM
,
Veal GJ
(2010).
Malnourished Malawian patients presenting with large Wilms tumours have a decreased vincristine clearance rate
.
Eur J Cancer
2010; 46:1841-7.
DOI
Leslie Elsner
,
Perris F. Flügge
,
Jingky Lozano
,
Vijayakumar Muppala
,
Britta Eiz-Vesper
,
Sara Y. Demiroglu
,
Dörthe Malzahn
,
Thomas Herrmann
,
Edgar Brunner
,
Heike Bickeböller
,
Gabriele Multhoff
,
Lutz Walter
,
Ralf Dressel
(2010).
The endogenous danger signals HSP70 and MICA cooperate in the activation of cytotoxic effector functions of NK cells
.
Journal of Cellular and Molecular Medicine
.
Cite
DOI
URL
Sawcer S
,
Ban M
,
Wason J
,
Dudbridge F
(2010).
What role for genetics in the prediction of multiple sclerosis?
.
Ann Neurol
2010; 67:3-10.
DOI
Bray J
,
Sludden J
,
Griffin MJ
,
Cole M
,
Verrill M
,
Jamieson D
,
Boddy AV
(2010).
Influence of pharmacogenetics on response and toxicity in breast cancer patients treated with doxorubicin and cyclophosphamide
.
Br J Cancer
2010; 102:1003-9.
DOI
Carr-Wilkinson J
,
O'Toole K
,
Wood KM
,
Challen CC
,
Baker AG
,
Board JR
,
Evans L
,
Cole M
,
Cheung N-KV
,
Boos J
,
Köhler G
,
Leuschner I
,
Pearson ADJ
,
Lunec J
,
Tweddle DA
(2010).
High Frequency of p53/MDM2/p14ARF pathway abnormalities in relapsed neuroblastoma
.
Clin Cancer Res
2010; 16:1108–18.
DOI
Griffiths B
,
Emery P
,
Ryan V
,
Isenberg D
,
Akil M
,
Thompson R
,
Maddison P
,
Griffiths ID
,
Lorenzi A
,
Miles S
,
Situnayake D
,
Teh LS
,
Plant M
,
Hallengren C
,
Nived O
,
Sturfelt G
,
Chakravarty K
,
Tait T
,
Gordon C
(2010).
The BILAG multi-centre open randomized controlled trial comparing ciclosporin vs azathioprine in patients with severe SLE
.
Rheumatology
2010; 49:723-32.
DOI
Brown BD
,
Nsengimana J
,
Barrett JH
,
Lawrence RA
,
Steiner L
,
Cheng S
,
Timothy Bishop D
,
Samani NJ
,
Ball SG
,
Balmforth AJ
,
Hall AS
(2010).
An evaluation of inflammatory gene polymorphisms in sibships discordant for premature coronary artery disease: The GRACE-IMMUNE study
.
BMC Med
2010; 8:5.
DOI
Mitchell SA
,
Miles CL
,
Brennan L
,
Matthews J
(2010).
Reliability of the School Food Checklist for in-school audits and photograph analysis of children's packed lunches
.
J Hum Nutr Diet
2010; 23:48-53.
DOI
Dörthe Malzahn
,
Yesilda Balavarca
,
Jingky P Lozano
,
Heike Bickeböller
(2009).
Tests for candidate-gene interaction for longitudinal quantitative traits measured in a large cohort
.
BMC Proceedings
.
Cite
DOI
URL
Cordell HJ
,
Ainsworth HF
,
Unwin J
(2009).
Investigation of maternal effects, maternal-foetal interactions and parent-of-origin effects (imprinting), using mothers and their offspring
.
Genet Epidemiol
2009; 33:752-835.
DOI
Tan MP
,
Newton JL
,
Chadwick TJ
,
Gray JC
,
Nath S
,
Parry SW
(2009).
Home orthostatic training in vasovagal syncope modifies autonomic tone: Results of a randomized, placebo-controlled pilot study
.
Europace
2010; 12:240-6.
DOI
Tan MP
,
Newton JL
,
Reeve P
,
Murray A
,
Chadwick TJ
,
Parry SW
(2009).
Results of carotid sinus massage in a tertiary referral unit—is carotid sinus syndrome still relevant?
.
Age Ageing
2009; 38:680-6.
DOI
Conway C
,
Mitra A
,
Jewell R
,
Randerson-Moor J
,
Lobo S
,
Nsengimana J
,
Edward S
,
Sanders DS
,
Cook M
,
Powell B
,
Boon A
,
Elliott F
,
de Kort F
,
Knowles MA
,
Bishop DT
,
Newton-Bishop J
(2009).
Gene expression profiling of paraffin-embedded primary melanoma using the DASL assay identifies increased osteopontin expression as predictive of reduced relapse-free survival
.
Clin Cancer Res
2009; 15:6939-46.
DOI
Skinner R
,
Parry A
,
Price L
,
Cole M
,
Craft AW
,
Pearson ADJ
(2009).
Persistent nephrotoxicity during 10-year follow-up after cisplatin or carboplatin treatment in childhood: Relevance of age and dose as risk factors
.
Eur J Cancer
2009; 45:3213-9.
DOI
Papakonstantinou L
,
Leslie P
,
Gray J
,
Chadwick T
,
Hudson M
,
Wilson JA
(2009).
Laryngopharyngeal reflux: A prospective analysis of a 34 item symptom questionnaire
.
Clin Otolaryngol
2009; 34:455-459.
DOI
Veal GJ
,
Cole M
,
Errington J
,
Pearson ADJ
,
Gerrard M
,
Whyman G
,
Ellershaw C
,
Boddy AV
(2009).
Pharmacokinetics of carboplatin and etoposide in infant neuroblastoma patients
.
Cancer Chemoth Pharm
2009; 65:1057-66.
DOI
Bell S
,
Parker L
,
Cole M
,
Craft AW
(2009).
Screening infants for neuroblastoma: The parents' perspective
.
Pediatr Hemat Oncol
1994; 11:433-7.
DOI
Rice A
,
Nsengimana J
,
Simmons IG
,
Toomes C
,
Hoole J
,
Willoughby CE
,
Cassidy F
,
Williams GA
,
George ND
,
Sheridan E
,
Young TL
,
Hunter TI
,
Barrett BT
,
Elliott DB
,
Bishop DT
,
Inglehearn CF
(2009).
Replication of the recessive STBMS1 locus but with dominant inheritance
.
Invest Ophth Visual
2009; 50:3210.
DOI
Zaremba T
,
Ketzer P
,
Cole M
,
Coulthard S
,
Plummer ER
,
Curtin NJ
(2009).
Poly(ADP-ribose) polymerase-1 polymorphisms, expression and activity in selected human tumour cell lines
.
Br J Cancer
2009; 101:256-62.
DOI
Xue X
,
Teare MD
,
Holen I
,
Zhu YM
,
Woll PJ
(2009).
Optimizing the yield and utility of circulating cell-free DNA from plasma and serum
.
Clin Chim Acta
2009; 404:100-4.
DOI
Rapley EA
,
Turnbull C
,
Amin Al Olama A
,
Dermitzakis ET
,
Linger R
,
Huddart RA
,
Renwick A
,
Hughes D
,
Hines S
,
Seal S
,
Morrison, J
,
Nsengimana J
,
Deloukas P
,
Rahman N
,
Bishop DT
,
Easton DF
,
Stratton MR
(2009).
A genome-wide association study of testicular germ cell tumor
.
Nat Genet
2009; 41:807-10.
DOI
Craigie AM
,
Matthews JNS
,
Rugg-Gunn AJ
,
Lake AA
,
Mathers JC
,
Adamson AJ
(2009).
Raised adolescent body mass index predicts the development of adiposity and a central distribution of body fat in adulthood: A longitudinal study
.
Obes Facts
2009; 2:150-6.
DOI
Parry SW
,
Chadwick T
,
Gray JC
,
Bexton RS
,
Tynan M
,
Bourke JP
,
Nath S
(2009).
The intravenous adenosine test: A new test for the identification of bradycardia pacing indications? A pilot study in subjects with bradycardia pacing indications, vasovagal syncope and controls
.
QJM: Int J Med
2009; 102:461–8.
DOI
Ban M
,
Goris A
,
Lorentzen A
,
Baker A
,
Mihalova T
,
Ingram G
,
Booth D
,
Heard R
,
Stewart G
,
Bogaert E
,
Dubois B
,
Harbo H
,
Celius E
,
Spurkland A
,
Strange R
,
Hawkins C
,
Robertson N
,
Dudbridge F
,
Wason J
,
De Jager P
,
Hafler D
,
Rioux J
,
Ivinson A
,
McCauley J
,
Pericak-Vance M
,
Oksenberg J
,
Hauser S
,
Sexton D
,
Haines J
,
Sawcer S
,
Wellcome Trust Case-Control Consortium
,
Compston A
(2009).
Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor
.
Eur J Hum Genet
2009; 17:1309-13.
DOI
Aitkin M
,
Liu CC
,
Chadwick T
(2009).
Bayesian model comparison and model averaging for small-area estimation
.
Ann Appl Stat
2009; 3:199-221.
DOI
Forrest I
,
Ward C
,
Murphy D
,
Ryan V
,
Johnson G
,
Lordan J
,
Fisher A
,
Cawston T
,
Corris P
(2009).
520: Bronchalveolar lavage neutrophilia and MMP-9 at 3 months post lung transplantation may predict the development of BOS
.
J Heart Lung Transpl
2009; 28:S246.
DOI
Rankin J
,
Chadwick T
,
Natarajan M
,
Howel D
,
Pearce MS
,
Pless-Mulloli T
(2009).
Maternal exposure to ambient air pollutants and risk of congenital anomalies
.
Environ Res
2009; 109:181-7.
DOI
Schiessl B
,
Innes BA
,
Bulmer JN
,
Otun HA
,
Chadwick TJ
,
Robson SC
,
Lash GE
(2008).
Localization of angiogenic growth factors and their receptors in the human placental bed throughout normal human pregnancy
.
Placenta
2009; 30:79-87.
DOI
Tan MP
,
Newton JL
,
Chadwick TJ
,
Parry SW
(2008).
The relationship between carotid sinus hypersensitivity, orthostatic hypotension, and vasovagal syncope: A case–control study
.
Europace
2008; 10:1400–5.
DOI
Rhodin MM
,
Anderson BJ
,
Peters AM
,
Coulthard MG
,
Wilkins B
,
Cole M
,
Chatelut E
,
Grubb A
,
Veal GJ
,
Keir MJ
,
Holford NHG
(2008).
Human renal function maturation: A quantitative description using weight and postmenstrual age
.
Pediatr Nephrol
2009; 24:67-76.
DOI
Nsengimana J
,
Barrett JH
(2008).
Power, validity, bias and robustness of family-based association analysis methods in the presence of linkage for late onset diseases
.
Ann Hum Genet
2008; 72:793-800.
DOI
Tan MP
,
Newton JL
,
Chadwick T
,
Parry SW
(2008).
Changes in baroreflex sensitivity with home orthostatic training in vasovagal syncope - A randomized, placebo controlled pilot study
.
Hypertension
2008; 52:747-75.
DOI
Chinnaswamy G
,
Cole M
,
Boddy AV
,
Keir M
,
Price L
,
Parry A
,
English M
,
Veal GJ
(2008).
Estimation of renal function and its potential impact on carboplatin dosing in children with cancer
.
Brit J Cancer
2008; 99:894-9.
DOI
Chinnaswamy G
,
Cole M
,
Boddy AV
,
Keir M
,
Price L
,
Parry A
,
English M
,
Veal GJ
(2008).
Estimation of renal function and its potential impact on carboplatin dosing in children with cancer
.
Br J Cancer
2008; 99:894-9.
DOI
Matheson EC
,
Cole M
,
Wilkinswand BS
,
Hall AG
(2008).
Mismatch repair defects in childhood acutelymphoblastic leukaemia at diagnosis and relapse
.
Brit J Haematol
2008; 141:1-121.
DOI
Coleman S
,
Fouweather T
,
Stewardson D
(2008).
Introduction: ENBIS, pro-ENBIS and this book
. In Coleman S et al (eds),
Statistical Practice in Business and Industry
.
DOI
Frank B
,
Serpell MG
,
Hughes J
,
Matthews JNS
,
Kapur D
(2008).
Comparison of analgesic effects and patient tolerability of nabilone and dihydrocodeine for chronic neuropathic pain: Randomised, crossover, double blind study
.
BMJ
2008; 336:199.
DOI
Nsengimana J
,
Barrett JH
(2007).
Renin–angiotensin system genes and coronary artery calcification
.
Future Cardiol
2007; 3:587-90.
DOI
Lee JS
,
Verrill MW
,
Sludden J
,
Griffin MJ
,
Erb S
,
Sumpter KA
,
Cole M
,
Calvert AH
,
Boddy AV
(2007).
Pharmacogenetic influences on outcome from AC chemotherapy in the treatment of breast cancer
.
Breast Cancer Res Tr
2007; 106:1-350.
DOI
Fouweather T
,
Coleman S
,
Thomas A
(2007).
Six sigma training programmes to help SMEs improve
.
Intelligent Production Machines and Systems
2006; 2nd I*PROMS Virtual International Conference 3–14 July 2006:39-44.
DOI
Leslie Elsner
,
Vijayakumar Muppala
,
Mathias Gehrmann
,
Jingky Lozano
,
Dörthe Malzahn
,
Heike Bickeböller
,
Edgar Brunner
,
Marta Zientkowska
,
Thomas Herrmann
,
Lutz Walter
,
Frauke Alves
,
Gabriele Multhoff
,
Ralf Dressel
(2007).
The Heat Shock Protein HSP70 Promotes Mouse NK Cell Activity against Tumors That Express Inducible NKG2D Ligands
.
The Journal of Immunology
.
Cite
DOI
URL
Johnson MI
,
Merrilees D
,
Robson WA
,
Lennon T
,
Masters J
,
Orr KE
,
Matthews JNS
,
Neal DE
(2007).
Oral ciprofloxacin or trimethoprim reduces bacteriuria after flexible cystoscopy
.
BJU Int
2007; 100:826-9.
DOI
Kosta K
,
Sabroe I
,
Göke J
,
Nibbs RJ
,
Tsanakas J
,
Whyte MK
,
Teare MD
(2007).
A Bayesian approach to copy-number–polymorphism analysis in nuclear pedigrees
.
Am J Hum Genet
2007; 81:808-12.
DOI
Chinnaswamy G
,
Veal GJ
,
Cole M
,
Taylor GA
,
Errington JE
,
Gerrard M
,
Boddy AV
(2007).
Pharmacogenetics and metabolism of cyclophosphamidein paediatric cancer patients
.
Pediatr Blood Cancer
2007; 49:398-605.
DOI
Chen L
,
Malcolm AJ
,
Wood KM
,
Cole M
,
Variend S
,
Cullinane C
,
Pearson ADJ
,
Lunec J
,
Tweddle DA
(2007).
p53 is nuclear and functional in both undifferentiated and differentiated neuroblastoma
.
Cell Cycle
2007; 6:2685-96.
DOI
Foster E
,
O'Keeffe M
,
Matthews JNS
,
Mathers JC
,
Nelson M
,
Barton KL
,
Wrieden WL
,
Adamson AJ
(2007).
Children's estimates of food portion size: The effect of timing of dietary interview on the accuracy of children′s portion size estimates
.
Brit J Nutr
2007; 99:185-90.
DOI
Routledge D
,
Jackson A
,
Bourn D
,
Bown N
,
Cole M
,
Slatter MA
,
Gennery AR
,
Curtis A
(2007).
Quantitative assessment of mixed chimerism in allogeneic stem cell transplant patients: A comparison of molecular genetic and cytogenetic approaches
.
J Pediat Hematol Onc
2007; 29:428-31.
DOI
Veal GJ
,
Cole M
,
Errington J
,
Pearson ADJ
,
Foot ABM
,
Whyman G
,
Boddy AV
(2007).
Pharmacokinetics and metabolism of 13-cis-retinoic acid (isotretinoin) in children with high-risk neuroblastoma – A study of the United Kingdom Children′s Cancer Study Group
.
Brit J Cancer
2007; 96:424-31.
DOI
Veal GJ
,
Cole M
,
Errington J
,
Pearson ADJ
,
Foot ABM
,
Whyman G
,
Boddy AV
(2007).
Pharmacokinetics and metabolism of 13-cis-retinoic acid (isotretinoin) in children with high-risk neuroblastoma – A study of the United Kingdom Children's Cancer Study Group
.
Br J Cancer
2007; 96:424-31.
DOI
Boisseau O
,
Matthews J
,
Gillespie D
,
Lacey C
,
Moscrop A
,
El Ouamari N
(2007).
A visual and acoustic survey for harbour porpoises off North-West Africa: Further evidence of a discrete population
.
Afr J Mar Sci
2007; 29:403-10.
DOI
Heike Bickeböller
,
Katrina A. B. Goddard
,
Robert P. Igo
,
Peter Kraft
,
Jingky P. Lozano
,
Nathan Pankratz and
(2007).
Issues in association mapping with high-density SNP data and diverse family structures
.
Genetic Epidemiology
.
Cite
DOI
URL
Teare MD
,
Woll PJ
(2007).
Genomic tests: Unreliable for cancer? A focus on circulating DNA and lung cancer
.
Expert Rev Mol Diagn
2014; 7:699-702.
DOI
Nsengimana J
,
Samani NJ
,
Hall AS
,
Balmforth AJ
,
Mangino M
,
Yuldasheva N
,
Maqbool A
,
Braund P
,
Burton P
,
Bishop DT
,
Ball SG
,
Barrett JH
(2006).
Enhanced linkage of a locus on chromosome 2 to premature coronary artery disease in the absence of hypercholesterolemia
.
Eur J Hum Genet
2006; 15:313-9.
DOI
Edwards R
,
Pless-Mulloli T
,
Howel D
,
Chadwick T
,
Bhopal R
,
Harrison R
,
Gribbin H
(2006).
Does living near heavy industry cause lung cancer in women? A case-control study using life grid interviews
.
Thorax
2006; 61:1076-82.
DOI
Teare MD
,
Heighway J
,
Santibáñez Koref MF
(2006).
An expectation-maximization algorithm for the analysis of allelic expression imbalance
.
Am J Hum Genet
2006; 79:P539-43.
DOI
Cole M
,
Boddy AV
,
Kearns P
,
Teh KH
,
Price L
,
Parry A
,
Pearson ADJ
,
Veal GJ
(2006).
Potential clinical impact of taking multiple blood samples for research studies in paediatric oncology: How much do we really know?
.
Pediatr Blood Cancer
2006; 46:723-7.
DOI
Mackintosh J
,
White M
,
Howel D
,
Chadwick T
,
Moffatt S
,
Deverill M
,
Sandell A
(2006).
Randomised controlled trial of welfare rights advice accessed via primary health care: Pilot study [ISRCTN61522618]
.
BMC Public Health
2006; 6:162.
DOI
Cole M
,
Price L
,
Parry A
,
Picton S
,
Waters F
,
Marshall S
,
Goran C
,
Parnham A
,
Wastell H
,
Reid MM
,
Pearson ADJ
,
Boddy AV
,
Veal GJ
(2006).
A study to determine the minimum volume of blood necessary to be discarded from a central venous catheter before a valid sample is obtained in children with cancer
.
Pediatr Blood Cancer
2007; 48:687-95.
DOI
Berrington JE
,
Cant AJ
,
Matthews JNS
,
O'Keeffe M
,
Spickett GP
,
Fenton AC
(2006).
Haemophilus influenzae type b immunization in infants in the United Kingdom: Effects of Diphtheria/Tetanus/Acellular Pertussis/Hib combination vaccine, significant prematurity, and a fourth dose
.
Pediatrics
2006; 117:e717-24.
DOI
Douglas SA
,
Webster S
,
El Badawey MR
,
Drinnan M
,
Matthews JN
,
Gibson GJ
,
Wilson JA
(2006).
The development of a snoring symptoms inventory
.
Otolaryng Head Neck
2006; 134:56-62.
DOI
Nsengimana J
,
Renard H
,
Goldgar D
(2005).
Linkage analysis of complex diseases using microsatellites and single-nucleotide polymorphisms: Application to alcoholism
.
BMC Genet
2005; 6:S10.
DOI
Ward C
,
Reid DW
,
Orsida BE
,
Feltis B
,
Ryan VA
,
Johns DP
,
Walters EH
(2005).
Inter-relationships between airway inflammation, reticular basement membrane thickening and bronchial hyper-reactivity to methacholine in asthma; a systematic bronchoalveolar lavage and airway biopsy analysis
.
Clin Exp Allergy
2005; 35:1565-71.
DOI
Teare MD
,
Barrett JH
(2005).
Genetic linkage studies
.
The Lancet
366:P1036-44.
DOI
Veal GJ
,
Cole M
,
Errington J
,
Parry A
,
Hale J
,
Pearson ADJ
,
Howe K
,
Chisholm JC
,
Beane C
,
Brennan B
,
Waters F
,
Glaser A
,
Hemsworth S
,
McDowell H
,
Wright Y
,
Pritchard-Jones K
,
Pinkerton R
,
Jenner G
,
Nicholson J
,
Elsworth AM
,
Boddy AV
(2005).
Pharmacokinetics of dactinomycin in a pediatric patient population: A United Kingdom Children's Cancer Study Group Study
.
Clin Cancer Res
2005; 11:5893-9.
DOI
Aitkin M
,
Boys RJ
,
Chadwick T
(2005).
Bayesian point null hypothesis testing via the posterior likelihood ratio
.
Stat Comput
2005; 15:217-30.
DOI
MacPherson G
,
Healey CS
,
Teare MD
,
Balasubramanian SP
,
Reed MWR
,
Pharoah PDP
,
Ponder BAJ
,
Meuth M
,
Bhattacharyya NP
,
Cox A
(2004).
Association of a common variant of the CASP8 gene with reduced risk of breast cancer
.
JNCI: J Natl Cancer Inst
2004; 96:1866-9.
DOI
Adams J
,
Ryan V
,
White M
(2004).
How accurate are Townsend Deprivation Scores as predictors of self-reported health? A comparison with individual level data
.
J Public Health
2005; 27:101-6.
DOI
Waldron MNH
,
Matthews JNS
,
Johnson IJM
(2004).
The effect of otitis media with effusions on balance in children
.
Clin Otolaryngol Allied Sci
2004; 29:318-20.
DOI
Teare MD
,
Cox A
,
Shorto J
,
Anderson C
,
Bishop DT
,
Cannings C
(2004).
Heterozygote excess is repeatedly observed in females at the BRCA2 locus N372H
.
J Med Genet
2004; 41:523-8.
DOI
Wallis JP
,
Wells AW
,
Matthews JN
,
Chapman CE
(2004).
Long-term survival after blood transfusion: A population based study in the North of England
.
Transfusion
2004; 44:1025-32.
DOI
Nsengimana J
,
Baret PV
(2004).
Linkage disequilibrium and the genetic distance in livestock populations: The impact of inbreeding
.
Genet Sel Evol
2004; 36:281.
DOI
Matthews JNS
,
Allcock GC
(2004).
Optimal designs for Michaelis–Menten kinetic studies
.
Stat Med
2004; 23:477-91.
DOI
Cole M
,
Price L
,
Parry A
,
Keir MJ
,
Pearson ADJ
,
Boddy AV
,
Veal GJ
(2004).
Estimation of glomerular filtration rate in paediatric cancer patients using 51CR-EDTA population pharmacokinetics
.
Br J Cancer
2004; 90:60–4.
DOI
Hanks S
,
Adams S
,
Douglas J
,
Arbour L
,
Atherton DJ
,
Balci S
,
Bode H
,
Campbell ME
,
Feingold M
,
Keser G
,
Kleijer W
,
Mancini G
,
McGrath JA
,
Muntoni F
,
Nanda A
,
Teare MD
,
Warman M
,
Pope FM
,
Superti-Furga A
,
Futreal PA
,
Rahman N
(2003).
Mutations in the gene encoding capillary morphogenesis protein 2 cause juvenile hyaline fibromatosis and infantile systemic hyalinosis
.
Am J Hum Genet
2003; 73:791-800.
DOI
Rahman N
,
Dunstan M
,
Teare MD
,
Hanks S
,
Douglas J
,
Coleman K
,
Bottomly WE
,
Campbell ME
,
Berglund B
,
Nordenskjold M
,
Forssell B
,
Burrows N
,
Lunt P
,
Young I
,
Williams N
,
Bignell GR
,
Futreal PA
,
Pope FM
(2003).
Ehlers-Danlos syndrome with severe early-onset periodontal disease (EDS-VIII) is a distinct, heterogeneous disorder with one predisposition gene at chromosome 12p13
.
Am J Hum Genet
2003; 73:198-204.
DOI
Edwards SM
,
Kote-Jarai Z
,
Meitz J
,
Hamoudi R
,
Hope Q
,
Osin P
,
Jackson R
,
Southgate C
,
Singh R
,
Falconer A
,
Dearnaley DP
,
Ardern-Jones A
,
Murkin A
,
Dowe A
,
Kelly J
,
Williams S
,
Oram R
,
Stevens M
,
Teare DM
,
Ponder BA
,
Gayther SA
,
Easton DF
,
RA Eeles
,
Cancer Research UK/Bristish Prostate Group UK Familial Prostate Cancer Study Collaborators
,
British Association of Urological Surgeons Section of Oncology
(2003).
Two percent of men with early-onset prostate cancer harbor germline mutations in the BRCA2 gene
.
Am J Hum Genet
2003; 72:1-12.
DOI
Bayly PJM
,
Matthews JN
,
Dobson PM
,
Price ML
,
Thomas DG
(2002).
In-hospital mortality from abdominal aortic surgery in Great Britain and Ireland: Vascular Anaesthesia Society audit
.
Br J Surg
2002; 88:687-92.
DOI
McEntagart M
,
Dunstan M
,
Bell C
,
Boltshauser E
,
Donaghy M
,
Harper PS
,
Williams N
,
Teare MD
,
Rahman N
(2002).
Clinical and genetic heterogeneity in peroneal muscular atrophy associated with vocal cord weakness
.
J Neurol Neurosurg Psychiatry
2002; 73:762-5.
DOI
Thomas HD
,
Porter DJ
,
Bartelink I
,
Nobbs JR
,
Cole M
,
Elliott S
,
Newell DR
,
Calvert AH
,
Highley M
,
Boddy AV
(2002).
Randomized cross-over clinical trial to study potential pharmacokinetic interactions between cisplatin or carboplatin and etoposide
.
Brit J Clin Pharmaco
2002; 53(1):83-91.
DOI
Rahman N
,
Dunstan M
,
Teare MD
,
Hanks S
,
Edkins SJ
,
Hughes J
,
Bignell GR
,
Mancini G
,
Kleijer W
,
Campbell M
,
Keser G
,
Black C
,
Williams N
,
Arbour L
,
Warman M
,
Superti-Furga A
,
Futreal PA
,
Pope FM
(2002).
The gene for juvenile hyaline fibromatosis maps to chromosome 4q21
.
Am J Hum Genet
2002; 71:975-80.
DOI
Lewis SC
,
Langman MJS
,
Laporte J-R
,
Matthews JNS
,
Rawlins MD
,
Wiholm b-E
(2002).
Dose–response relationships between individual nonaspirin nonsteroidal anti-inflammatory drugs (NANSAIDs) and serious upper gastrointestinal bleeding: A meta-analysis based on individual patient data
.
Br J Clin Pharmacol
2002; 54:320-6.
DOI
Burns ASYW
,
Jaros E
,
Cole M
,
Perry R
,
Pearson AJ
,
Lunec J
(2002).
The molecular pathology of p53 in primitive neuroectodermal tumours of the central nervous system
.
Br J Cancer
2002; 86:1117-23.
DOI
Thompson D
,
Szabo Ci
,
Mangion J
,
Oldenburg RA
,
Odefrey F
,
Seal S
,
Barfoot R
,
Kroeze-Jansema K
,
Teare D
,
Rahman N
,
Renard H
,
Mann G
,
Hopper JL
,
Buys SS
,
Andrulis IL
,
Senie R
,
Daly MB
,
West D
,
Ostrander EA
,
Offit K
,
Peretz T
,
Osorio A
,
Benitez J
,
Nathanson KL
,
Sinilnikova OM
,
Olah E
,
Bignon Y-J
,
Ruiz P
,
Badzioch MD
,
Vasen HFA
,
Futreal AP
,
Phelan CM
,
Narod SA
,
Lynch HT
,
Ponder BAJ
,
Eeles RA
,
Meijers-Heijboer H
,
Stoppa-Lyonnet D
,
Couch FJ
,
Eccles DM
,
Evans DG
,
Chang-Claude J
,
Lenoir G
,
Weber BL
,
Devilee P
,
Easton DF
,
Goldgar DE
,
Stratton MR
(2002).
Evaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage Consortium
.
Proc Natl Acad Sci USA
2002; 99:827-31.
DOI
Matthews JN
(2002).
Methods for the analysis and design of limiting dilution assays
.
Dev Biologicals
2002; 107:87-94.
Hateboer N
,
Gumbs C
,
Teare MD
,
Coles GA
,
Griffiths D
,
Ravine D
,
Futreal PA
,
Rahman N
(2001).
Confirmation of a gene locus for medullary cystic kidney disease (MCKD2) on chromosome 16p12
.
Kidney Int
2001; 60:1233-9.
DOI
McEntagart M
,
Norton N
,
Williams H
,
Teare MD
,
Dunstan M
,
Baker P
,
Houlden H
,
Reilly M
,
Wood N
,
Harper PS
,
Futreal PA
,
Williams N
,
Rahman N
(2001).
Localization of the gene for distal hereditary motor neuronopathy VII (dHMN-VII) to chromosome 2q14
.
Am J Hum Genet
2001; 68:1270-6.
DOI
Yule SM
,
Price L
,
Cole M
,
Pearson AD
,
Boddy AV
(2001).
Cyclophosphamide metabolism in children following a 1-h and a 24-h infusion
.
Cancer Chemoth Pharm
2001; 47:222-8.
DOI
Levett D
,
Middleton P
,
Cole M
,
Reid MM
(2001).
A demographic study of the clinical significance of minimal residual disease in children with acute lymphoblastic leukemia
.
Med Pediatr Oncol
2001; 36:365-71.
DOI
Tweddle DA
,
Pinkerton CR
,
Lewis IJ
,
Ellershaw C
,
Cole M
,
Pearson ADJ
(2001).
OPEC/OJEC for stage 4 neuroblastoma in children over 1 year of age
.
Med Pediatr Oncol
2001; 36:239-42.
DOI
Dunning AM
,
Durocher F
,
Healey CS
,
Teare MD
,
McBride SE
,
Carlomagno F
,
Xu CF
,
Dawson E
,
Rhodes S
,
Ueda S
,
Lai E
,
Luben RN
,
Van Rensburg EJ
,
Mannermaa A
,
Kataja V
,
Rennart G
,
Dunham I
,
Purvis I
,
Easton D
,
Ponder BAJ
(2000).
The extent of linkage disequilibrium in four populations with distinct demographic histories
.
Am J Hum Genet
2000; 67:1544-54.
DOI
Weiss MJ
,
Guo C
,
Shusterman S
,
Hii G
,
Mirensky TL
,
White PS
,
Hogarty MD
,
Rebbeck TR
,
Teare D
,
Urbanek M
,
Brodeur GM
,
Maris JM
(2000).
Localization of a hereditary neuroblastoma predisposition gene to 16p12-p13
.
Med Pediatr Oncol
2000; 35:526–530.
DOI
Keegan PE
,
Matthews JNS
,
Lunec J
,
Neal DE
(2000).
Statistical problems with ‘optimal' thresholds in studies of new prognostic factors in urology
.
BJU Int
2000; 85:392-7.
DOI
Forrest MS
,
Edwards SM
,
Hamoudi RA
,
Dearnaley DP
,
Arden-Jones A
,
Dowe A
,
Murkin A
,
Kelly J
,
Teare MD
,
DF Easton
,
MA Knowles
,
DT Bishop
,
RA Eeles
,
The CRC/BPG UK Familial Prostate Cancer Study Collaborators
,
The EC Biomed Familial Prostate Cancer Study Collaborators
(2000).
No evidence of germline PTEN mutations in familial prostate cancer
.
J Med Genet
2000; 37:210-2.
DOI
Healey CS
,
Dunning AM
,
Durocher F
,
Teare D
,
Pharoah PDP
,
Luben RN
,
Easton DF
,
Ponder BAJ
(2000).
Polymorphisms in the human aromatase cytochrome P450 gene (CYP19) and breast cancer risk
.
Carcinogenesis
2000; 21:189-93.
DOI
Dunning AM
,
Healey CS
,
Pharoah PDP
,
Teare MD
,
Ponder BAJ
,
Easton DF
(1999).
A systematic review of genetic polymorphisms and breast cancer risk
.
Cancer Epidemiol Biomarkers Prev
1999; 8:843-54.
Shugart YY
,
Cour C
,
Renard H
,
Lenoir G
,
Goldgar D
,
Teare D
,
Easton D
,
Rahman N
,
Gusterton R
,
Seal S
,
Barfoot R
,
Stratton M
,
Mangion J
,
Peelen T
,
van den Ouweland A
,
Meijers H
,
Devilee P
,
Eccles D
,
Lynch H
,
Weber B
,
Stoppa-Lyonnet D
,
Bignon YJ
,
Chang-Claude J
(1999).
Linkage analysis of 56 multiplex families excludes the Cowden disease genePTEN as a major contributor to familial breast cancer
.
J Med Genet
1999; 36:720-1.
DOI
Yule SM
,
Price L
,
Cole M
,
Pearson AD
,
Boddy AV
(1999).
Cyclophosphamide metabolism in children with Fanconi's anaemia
.
Bone Marrow Transplant
1999; 24:123-8.
DOI
Yule SM
,
Price L
,
Cole M
,
Pearson ADJ
,
Boddy AV
(1999).
Cyclophosphamide metabolism in children with Fanconi's anaemia
.
Bone Marrow Transpl
1999; 24:123-8.
DOI
Matthews JNS
(1999).
Sponsored trials do not necessarily give more-favourable results
.
BMJ
1999; 318:1762.
DOI
Yule SM
,
Walker D
,
Cole M
,
McSorley L
,
Cholerton S
,
Daly AK
,
Pearson ADJ
,
Boddy AV
(1999).
The effect of fluconazole on cyclophosphamide metabolism in children
.
Drug Metab Dispos
1999; 27:417-21.
McGaughran JM
,
Harris DI
,
Donnai D
,
Teare D
,
MacLeod R
,
Westerbeek R
,
Kingston H
,
Super M
,
Harris R
,
Evans DGR
(1999).
A clinical study of type 1 neurofibromatosis in north west England
.
J Med Genet
1999; 36:197-203.
DOI
Matthews JNS
(1999).
Alternative criteria for optimal designs of limiting dilution assays
.
Stat Med
1998; 17:2733-46.
DOI
Matthews JNS
,
Matthews DSF
,
Eyre JA
(1999).
Statistical method for the estimation of cerebral blood flow using the Kety-Schmidt technique
.
Clin Sci
1999; 97:485-92.
DOI
Matthews JNS
(1998).
A formula for the probability of discordant classification in method comparison studies
.
Statistics in Medicine
1997; 16:705-10.
DOI
Lowis SP
,
Price L
,
Pearson AD
,
Newell DR
,
Cole M
(1998).
A study of the feasibility and accuracy of pharmacokinetically guided etoposide dosing in children
.
Br J Cancer
1998; 77:2318-23.
DOI
Arason A
,
Jonasdottir A
,
Barkardottir RB
,
Bergthorsson JT
,
Teare MD
,
Easton DF
,
Egilsson V
(1998).
A population study of mutations and LOH at breast cancer gene loci in tumours from sister pairs: Two recurrent mutations seem to account for all BRCA1/BRCA2 linked breast cancer in Iceland
.
J Med Genet
1998; 35:446-9.
DOI
Eeles RA
,
Durocher F
,
Edwards S
,
Teare D
,
Badzioch M
,
Hamoudi R
,
Gill S
,
Biggs P
,
Dearnaley D
,
Ardern-Jones A
,
Dowe A
,
Shearer R
,
McLennan DL
,
Norman RL
,
Ghadirian P
,
Aprikian A
,
Ford D
,
Amos C
,
King TM
,
Labrie F
,
Simard J
,
Narod SA
,
Easton D
,
Foulkes WD
(1998).
Linkage analysis of chromosome 1q markers in 136 prostate cancer families
.
Am J Hum Genet
1998; 62:653-8.
DOI
Ford D
,
Easton DF
,
Stratton M
,
Narod S
,
Goldgar D
,
Devilee P
,
Bishop DT
,
Weber B
,
Lenoir G
,
Chang-Claude J
,
Sobol H
,
Teare MD
,
Struewing J
,
Arason A
,
Scherneck S
,
Peto J
,
Rebbeck TR
,
Tonin P
,
Neuhausen S
,
Barkardottir R
,
Eyfjord J
,
Lynch H
,
Ponder BAJ
,
Gayther SA
,
Birch JM
,
Lindblom A
,
Stoppa-Lyonnet D
,
Bignon Y
,
Borg A
,
Hamann U
,
Haites N
,
Scott RJ
,
Maugard CM
,
Vasen H
,
Seitz S
,
Cannon-Albright LA
,
Schofield A
,
Zelada-Hedman M
(1998).
Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families
.
Am J Hum Genet
1998; 62:676-89.
DOI
Mirza MM
,
Lee J
,
Teare D
,
Hugot JP
,
Laurent-Puig P
,
Colombel JF
,
Hodgson SV
,
Thomas G
,
Easton DF
,
Lennard-Jones JE
,
Mathew CG
(1998).
Evidence of linkage of the inflammatory bowel disease susceptibility locus on chromosome 16 (IBD1) to ulcerative colitis
.
J Med Genet
1998; 35:218-21.
DOI
Parker L
,
Cole M
,
Craft AW
,
Hey EN
(1998).
Neonatal vitamin K administration and childhood cancer in the north of England: Retrospective case-control study
.
BMJ
1998; 316:189-93.
DOI
Vernon SJ
,
Coulthard MG
,
Lambert HJ
,
Keir MJ
,
Matthews JNS
(1997).
New renal scarring in children who at age 3 and 4 years had had normal scans with dimercaptosuccinic acid: Follow up study
.
BMJ
1997; 315:905-8.
DOI
Rohde K
,
Teare MD
,
Santibanez Koref M
(1997).
Analysis of genetic linkage and somatic loss of heterozygosity in affected pairs of first-degree relatives
.
Am J Hum Genet
1997; 61:418-22.
DOI
Deshpande SA
,
Matthews JN
,
Platt MP
(1996).
Measuring blood glucose in neonatal units: How does hemocue compare?
.
Arch Dis Child Fetal Neonatal Ed
1996; 75:F202-8.
DOI
Matthews JNS
,
Altman DG
(1996).
Statistics Notes: Interaction 2: Compare effect sizes not P values
.
BMJ
1996; 313:808.
DOI
Altman DG
,
Matthews JNS
(1996).
Statistics Notes: Interaction 1: Heterogeneity of effects
.
BMJ
1996; 313:486.
DOI
Maddock IR
,
Moran A
,
Maher ER
,
Teare MD
,
Norman A
,
Payne SJ
,
Whitehouse R
,
Dodd C
,
Lavin M
,
Hartley N
,
Super M
,
Evans DG
(1996).
A genetic register for von Hippel-Lindau disease
.
J Med Genet
1996; 33:120-7.
DOI
Mazza D
,
Dennerstein L
,
Ryan V
(1996).
Physical, sexual and emotional violence against women: A general practice-based prevalence study
.
Med J Australia
1996; 164(1):14-17.
DOI
Yule SM
,
Boddy AV
,
Cole M
,
Price L
,
Wyllie R
,
Tasso MJ
,
Pearson ADJ
,
Idle JR
(1996).
Cyclophosphamide pharmacokinetics in children
.
Brit J Clin Pharmaco
1996; 41:13-9.
DOI
Cooper BG
,
Matthews JN
,
Alberti KG
(1995).
Resting energy expenditure, substrate use, and video tapes
.
BMJ
1995; 311:1664-5.
DOI
Scott JES
,
Wright B
,
Wilson G
,
Pearson IA
,
Matthews JNS
,
Rose PG
(1995).
Measuring the fetal kidney with ultrasonography
.
Br J Urol
1995; 76:769-74.
DOI
Varley JM
,
McGown G
,
Thorncroft M
,
Tricker KJ
,
Teare MD
,
Santibáñez Koref MF
,
Martin J
,
Birch JM
,
Evans DG
(1995).
An extended Li-Fraumeni kindred with gastric carcinoma and a codon 175 mutation in TP53
.
J Med Genet
1995; 32:942-5.
DOI
Peng B
,
Boddy AV
,
Cole M
,
Pearson ADJ
,
Chatelut E
,
Rubie H
,
Newell DR
(1995).
Comparison of methods for the estimation of carboplatin pharmacokinetics in paediatric cancer patients
.
Eur J Cancer
1995; 31:1804-10.
DOI
Matthews DS
,
Bullock RE
,
Matthews JN
,
Aynsley-Green A
,
Eyre JA
(1995).
Temperature response to severe head injury and the effect on body energy expenditure and cerebral oxygen consumption
.
Arch Dis Child
1995; 72:507-15.
DOI
Cole M
,
Craft AW
,
Parker L
,
Bell S
,
Seviour JA
,
McGill AC
,
Dale G
(1995).
Urinary creatinine adjusted reference ranges for homovanillic and vanillylmandelic acid in children and adults
.
Clin Chim Acta
1995; 236(1):19-32.
DOI
Lawrence CM
,
Matthews JNS
,
Cox NH
(1995).
The effect of ketanserin on healing of fresh surgical wounds
.
Br J Dermatol
1995; 132:580-6.
DOI
Craft AW
,
Parker L
,
Stiller C
,
Cole M
(1995).
Screening for wilms' tumour in patients with aniridia, Beckwith syndrome, or hemihypertrophy
.
Med Pediatr Oncol
1995; 224:231-4.
DOI
Matthews JNS
(1995).
Small clinical trials: Are they all bad?
.
Stat Med
1995; 14:115-26.
DOI
Boddy AV
,
Cole M
,
Pearson AD
,
Idle JR
(1995).
The kinetics of the auto-induction of ifosfamide metabolism during continuous infusion
.
Cancer Chemother Pharmacol
1995; 36:53-60.
DOI
Matthews JNS
,
Morris KP
(1995).
An application of Bradley-Terry-Type models to the measurement of pain
.
J R Stat Soc C - Appl
1995; 44:243-55.
DOI
Matthews JNS
(1994).
Multi-period crossover trials
.
Stat Meth Med Res
1994; 3:383-405.
DOI
Hall AG
,
Autzen P
,
Cattan AR
,
Malcolm AJ
,
Cole M
,
Kernahan J
,
Reid MM
(1994).
Expression of µ Class Glutathione S-Transferase Correlates with Event-free Survival in Childhood Acute Lymphoblastic Leukemia
.
Cancer Res
1994; 54:5251-4.
Bell S
,
Parker L
,
Cole M
,
Craft AW
(1994).
Screening infants for neuroblastoma: The parents' perspective in false-positive cases
.
Pediatr Hemat Oncol
1994; 11:157-63.
DOI
Teare MD
,
Rohde K
,
Santibáñez Koref MF
(1994).
The use of loss of constitutional heterozygosity data to ascertain the location of predisposing genes in cancer families
.
J Med Genet
1994; 31:448-52.
DOI
Skinner R
,
Cole M
,
Pearson AD
,
Keir MJ
,
Price L
,
Wyllie RA
,
Coulthard MG
,
Craft AW
(1994).
Inaccuracy of glomerular filtration rate estimation from height/plasma creatinine ratio
.
Arch Dis Child
1994; 70:387-90.
DOI
Sakuntabhai A
,
Matthews JNS
,
Farr PM
(1994).
Improved prediction of the minimal phototoxic dose in PUVA therapy
.
Br J Dermatol
1994; 130:604-9.
DOI
Wright CM
,
Matthews JNS
,
Waterston A
,
Aynsley-Green A
(1994).
What is a normal rate of weight gain in infancy?
.
Acta Paediatr
1994; 83:351-6.
DOI
Matthews JN
,
Hoenich NA
(1994).
Statistical aspects of the design and analysis of studies to compare haemodialysis membranes
.
Nephrol Dial Transpl
1994; 9(Suppl 2):176-183.
Bell S
,
Parker L
,
Craft AW
,
Dale G
,
McGill AC
,
Seviour J
,
Cole M
,
Smith J
(1994).
False positive results in a neuroblastoma screening programme
.
Med Pediatr Oncol
1994; 22:181-6.
DOI
Lowis SP
,
Pearson ADJ
,
Newell DR
,
Cole M
(1993).
Etoposide pharmacokinetics in children: The development and prospective validation of a dosing equation
.
Cancer Res
1993; 53:4881-9.
Perros P
,
Crombie AL
,
Matthews JNS
,
Kendall-Taylor P
(1993).
Age and gender influence the severity of thyroid-associated ophthalmopathy: A study of 101 patients attending a combined thyroid-eye clinic
.
Clin Endocrinol
1993; 38:367-72.
DOI
Cole M
,
Parker L
,
Craft AW
,
Bell S
,
Dale G
,
McGill AC
,
Seviour JA
,
Smith J
(1993).
Creatinine related reference ranges for urinary homovanillic acid and vanillylmandelic acid at 6 months of age
.
Arch Dis Child
1993; 68:376–8.
DOI
Matthews JNS
(1993).
A refinement to the analysis of serial data using summary measures
.
Stat Med
1993; 12:27-37.
DOI
Henderson R
,
Matthews JNS
(1993).
An investigation of changepoints in the annual number of cases of haemolytic uraemic syndrome
.
J R Stat Soc C - Appl
1993; 42:461-71.
DOI
Evans DG
,
Huson SM
,
Donnai D
,
Neary W
,
Blair V
,
Teare D
,
Newton V
,
Strachan T
,
Ramsden R
,
Harris R
(1992).
A genetic study of type 2 neurofibromatosis in the United Kingdom. I. Prevalence, mutation rate, fitness, and confirmation of maternal transmission effect on severity
.
J Med Genet
1992; 29:841-6.
DOI
Parker L
,
Craft AW
,
Dale G
,
Bell S
,
Cole M
,
McGill AC
,
Seviour JA
,
Smith J
(1992).
Screening for neuroblastoma in the north of England
.
BMJ
1992; 305:1260-3.
DOI
Craft AW
,
Parker L
,
Dale G
,
McGill AC
,
Seviour JA
,
Bell S
,
Cole M
,
Smith J
(1992).
A pilot study of screening for neuroblastoma in the north of England
.
Am J Pediatr Hematol Oncol
1992; 14:337-41.
Matthews JNS
,
Campbell MJ
,
Kaiser L
(1992).
Adjusting for baseline: Chamge or percentage change
.
Stat Med
1992; 11:1624-26.
DOI
Hartley AL
,
Birch JM
,
Blair V
,
Teare MD
,
Marsden HB
,
Harris M
(1991).
Cancer incidence in the families of children with Ewing's tumor
.
JNCI: J Natl Cancer Inst
1991; 83:955–7.
DOI
Farr PM
,
Diffey BL
,
Higgins EM
,
Matthews JNS
(1991).
The action spectrum between 320 and 400 nm for clearance of psoriasis by psoralen photochemotherapy
.
Br J Dermatol
1991; 124:443-8.
DOI
Royston P
,
Matthews JNS
(1991).
Estimation of reference ranges from normal samples
.
Stat Med
1991; 10:691-5.
DOI
Wheeler J
,
Matthews JNS
,
Morley AR
(1991).
Corrections in counting paired nuclei labelled with bromodeoxyuridine in tissue sections
.
Cell Prolif
1991; 24:143-57.
DOI
Birch JM
,
Hartley AL
,
Blair V
,
Kelsey AM
,
Harris M
,
Teare MD
,
Morris Jones PH
(1990).
Cancer in the families of children with soft tissue sarcoma
.
Cancer
1990; 66:2239-48.
DOI
Fletcher DJ
,
Lewis SM
,
Matthews JNS
(1990).
Factorial designs for crossover clinical trials
.
Stat Med
1990; 9:1121-9.
DOI
Hackett AF
,
Jarvis SN
,
Matthews JNS
(1990).
A study of the eating habits of 11- and 12-year-old children before and one year after the start of a healthy eating campaign in Northumberland
.
J Hum Nutr Diet
1990; 3:323-32.
DOI
Friedmann PS
,
Rees J
,
White SI
,
Matthews JN
(1990).
Low-dose exposure to antigen induces sub-clinical sensitization
.
Clin Exp Immunol
1990; 81:507-9.
DOI
Farr PM
,
Diffey BL
,
Matthews JNS
(1990).
Inhibition of photosensitivity in erythropoietic protoporphyria with terfenadine
.
Br J Dermatol
1990; 122:809-15.
DOI
Parrott NR
,
Forsythe JL
,
Matthews JNS
,
Lennard TW
,
Rigg KM
,
Proud G
,
Taylor RM
(1990).
Late perfusion: A simple remedy for renal allograft primary nonfunction
.
Transplantation
1990; 49:913-5.
Birch JM
,
Hartley AL
,
Blair V
,
Kelsey AM
,
Harris M
,
Teare MD
,
Jones PH
(1990).
Identification of factors associated with high breast cancer risk in the mothers of children with soft tissue sarcoma
.
J Clin Oncol
1990; 8:583-90.
DOI
Friedmann PS
,
Wren FE
,
Matthews JN
(1990).
Ultraviolet stimulated melanogenesis by human melanocytes is augmented by di-acyl glycerol but not TPA
.
J Cell Physiol
1990; 142:334-41.
DOI
Birch JM
,
Hartley AL
,
Teare MD
,
Blair V
,
McKinney PA
,
Mann JR
,
Stiller CA
,
Draper GJ
,
Johnston HE
,
Cartwright RA
,
Waterhouse JAH
(1990).
The inter-regional epidemiological study of childhood cancer (IRESCC): Case-control study of children with central nervous system tumours
.
Br J Neurosurg
1990; 4(1):17-25.
DOI
Rees JL
,
Friedmann PS
,
Matthews JNS
(1990).
The influence of area of application on sensitization by dinitrochlorobenzene
.
Br J Dermatol
1990; 122:29-31.
DOI
Hartley AL
,
Birch JM
,
Kelsey AM
,
Marsden HB
,
Harris M
,
Teare MD
(1989).
Are germ cell tumors part of the Li-Fraumeni cancer family syndrome?
.
Cancer Genet Cytogenet
1989; 42:221-6.
DOI
Potter JF
,
Heseltine D
,
Hartley G
,
Matthews J
,
Macdonald IA
,
James OFW
(1989).
Effects of meal composition on the postprandial blood pressure, catecholamine and insulin changes in elderly subjects
.
Clin Sci
1989; 77:265-72.
DOI
Rees JL
,
Friedmann PS
,
Matthews JNS
(1989).
Sex differences in susceptibility to development of contact hypersensitivity to dinitrochlorobenzene (DNCB)
.
Br J Dermatol
1989; 120:371-4.
DOI
Hartley AL
,
Birch JM
,
McKinney PA
,
Blair V
,
Teare MD
,
Carrette J
,
Mann JR
,
Stiller CA
,
Draper GJ
,
Johnston HE
(1988).
The inter-regional epidemiological study of childhood cancer (IRESCC): Past medical history in children with cancer
.
J Epidemiol Community Health
1988; 42:235-42.
DOI
Schofield CJ
,
Matthews JNS
(1985).
Theoretical approach to active dispersal and colonization of houses by Triatoma infestans
.
J Trop Med Hyg
1985; 88:211-22.
Matthews JNS
(1984).
Robust Methods in the Assessment of Multivariate Normality
.
J R Stat Soc C - Appl
1984; 33:272-7.
DOI
Adams N
,
Skelton D
,
Bailey C
,
Howel D
,
Coe D
,
Lampitt R
,
Wilkinson J
,
Fouweather T
,
de Jong LD
,
Gawler S
,
Deary V
,
Gray J
,
Waterman H
,
Parry SW
(0001).
Visually Impaired OLder people's Exercise programme for falls prevenTion (VIOLET): A feasibility study
.
Public Health Res
2019;7.
DOI
Wood CL
,
Cole M
,
Donaldson M
,
Dunger DB
,
Wood R
,
Morrison N
,
Matthews JNS
,
Pearce SHS
,
Cheetham TD
(0001).
Randomised trial of block and replace vs dose titration thionamide in young people with thyrotoxicosis
.
Eur J Endocrinol
2020; 183:637-45.
DOI
Murray J
,
Gulliford S
,
Griffin C
,
Wilkins A
,
Syndikus I
,
Staffurth J
,
Panades M
,
Scrase C
,
Parker C
,
Khoo V
,
Dean J
,
Mayles H
,
Mayles P
,
Thomas S
,
Naismith O
,
Mossop H
,
Cruickshank C
,
Hall E
,
Dearnaley D
(0001).
Evaluation of erectile potency and radiation dose to the penile bulb using image guided radiotherapy in the CHHiP trial
.
Clin Transl Radiat Oncol
2020; 21:77-84.
DOI
Howatson AG
,
Patrick WJA
,
Fell GS
,
Lyon TDB
,
Gibson AAM
,
Richardson BA
,
Mitchell EA
,
Scragg L
,
Clements M
,
Bell SA
,
Cole M
(0001).
Cot mattresses and sudden infant death syndrome
.
The Lancet
1995; 345:1044-6.
DOI
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