Nsengimana J
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- Identification of 22 susceptibility loci associated with testicular germ cell tumors
- SFPQ promotes an oncogenic transcriptomic state in melanoma
- Inherited duplications of PPP2R3B predispose to nevi and melanoma via a C21orf91-driven proliferative phenotype
- Transcriptional signatures underlying dynamic phenotypic switching and novel disease biomarkers in a linear cellular model of melanoma progression
- MX2 mediates establishment of interferon response profile, regulates XAF1, and can sensitize melanoma cells to targeted therapy
- Tumour gene expression signature in primary melanoma predicts long-term outcomes
- The role of CAF derived exosomal microRNAs in the tumour microenvironment of melanoma
- Cell state diversity promotes metastasis through heterotypic cluster formation in melanoma
- Gene co-expression and histone modification signatures are associated with melanoma progression, epithelial-to-mesenchymal transition, and metastasis
- Study of the female sex survival advantage in melanoma--A focus on X-linked epigenetic regulators and immune responses in two cohorts
- Factors affecting sentinel node metastasis in thin (T1) cutaneous melanomas: Development and external validation of a predictive nomogram
- Expression profiling of single cells and patient cohorts identifies multiple immunosuppressive pathways and an altered NK cell phenotype in glioblastoma
- Vitamin D–VDR signaling inhibits Wnt/β-Catenin–mediated melanoma progression and promotes antitumor immunity
- MX 2 is a novel regulator of cell cycle in melanoma cells
- A higher percentage of stroma within primary melanomas is associated with a protective effect on melanoma-specific survival
- Transcriptomic analysis reveals prognostic molecular signatures of stage I melanoma
- High-resolution copy number patterns from clinically relevant FFPE material
- ctDNA as a noninvasive monitoring tool in metastatic melanoma
- Genetic and environmental determinants of immune response to cutaneous melanoma
- Application of Circulating cell-free tumor DNA profiles for therapeutic monitoring and outcome prediction in genetically heterogeneous metastatic melanoma
- MYCexpression and smoking as drivers of failure of immune response to melanoma
- Primary melanoma expression of the vitamin D receptor (VDR) is protective for melanoma survival and is associated with increased tumor immune response, decreased Wnt/B-catenin signaling and tumor proliferation
- β-Catenin–mediated immune evasion pathway frequently operates in primary cutaneous melanomas
- Large-scale sequencing of testicular germ cell tumour (TGCT) cases excludes major TGCT predisposition gene
- Identification of a gene signature for discriminating metastatic from primary melanoma using a molecular interaction network approach
- Comparative genomics reveals that loss of lunatic fringe (LFNG) promotes melanoma metastasis
- Design considerations for genetic linkage and association studies
- A screen for combination therapies in BRAF/NRAS wild type melanoma identifies nilotinib plus MEK inhibitor as a synergistic combination
- Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor
- Higher serum 25‐hydroxyvitamin D levels at melanoma diagnosis are associated with better prognosis in patients with intermediate VDR‐expressing tumours, with transcriptomic evidence for inhibition of β‐catenin signalling
- Genomic expression differences between cutaneous cells from red hair color individuals and black hair color individuals based on bioinformatic analysis
- Consensus of melanoma gene expression subtypes converges on biological entities
- Identification of four new susceptibility loci for testicular germ cell tumour
- Prognostic significance of promoter hypermethylation and diminished gene expression of SYNPO2 in melanoma
- Independent replication of a melanoma subtype gene signature and evaluation of its prognostic value and biological correlates in a population cohort
- Multi-stage genome-wide association study identifies new susceptibility locus for testicular germ cell tumour on chromosome 3q25
- The clinicopathological and gene expression patterns associated with ulceration of primary melanoma
- Targeting human apurinic/apyrimidinic endonuclease 1 (APE1) in phosphatase and tensin homolog (PTEN) deficient melanoma cells for personalized therapy
- Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14
- Analysis of genetic interactions involving maternal and offspring genotypes at different loci: Power simulation and application to testicular cancer
- Germline MRE11 variants predictive of radiotherapy outcomes in bladder cancer by next-generation sequencing
- Design considerations for genetic linkage and association studies
- Multiple testing in high-throughput sequence data: Experiences from Group 8 of Genetic Analysis Workshop 17
- Two-stage analyses of sequence variants in association with quantitative traits
- Melanoma sentinel node biopsy and prediction models for relapse and overall survival
- Patterns of expression of DNA repair genes and relapse from melanoma
- Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer
- CCAAT/enhancer binding protein α, β and δ gene variants: Associations with obesity related phenotypes in the Leeds Family Study
- An evaluation of inflammatory gene polymorphisms in sibships discordant for premature coronary artery disease: The GRACE-IMMUNE study
- Gene expression profiling of paraffin-embedded primary melanoma using the DASL assay identifies increased osteopontin expression as predictive of reduced relapse-free survival
- Replication of the recessive STBMS1 locus but with dominant inheritance
- A genome-wide association study of testicular germ cell tumor
- Power, validity, bias and robustness of family-based association analysis methods in the presence of linkage for late onset diseases
- Renin–angiotensin system genes and coronary artery calcification
- Enhanced linkage of a locus on chromosome 2 to premature coronary artery disease in the absence of hypercholesterolemia
- Linkage analysis of complex diseases using microsatellites and single-nucleotide polymorphisms: Application to alcoholism
- Linkage disequilibrium and the genetic distance in livestock populations: The impact of inbreeding