Newton-Bishop J

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SFPQ promotes an oncogenic transcriptomic state in melanoma
Inherited duplications of PPP2R3B predispose to nevi and melanoma via a C21orf91-driven proliferative phenotype
Transcriptional signatures underlying dynamic phenotypic switching and novel disease biomarkers in a linear cellular model of melanoma progression
MX2 mediates establishment of interferon response profile, regulates XAF1, and can sensitize melanoma cells to targeted therapy
Tumour gene expression signature in primary melanoma predicts long-term outcomes
The role of CAF derived exosomal microRNAs in the tumour microenvironment of melanoma
Cell state diversity promotes metastasis through heterotypic cluster formation in melanoma
Gene co-expression and histone modification signatures are associated with melanoma progression, epithelial-to-mesenchymal transition, and metastasis
Study of the female sex survival advantage in melanoma--A focus on X-linked epigenetic regulators and immune responses in two cohorts
Factors affecting sentinel node metastasis in thin (T1) cutaneous melanomas: Development and external validation of a predictive nomogram
Expression profiling of single cells and patient cohorts identifies multiple immunosuppressive pathways and an altered NK cell phenotype in glioblastoma
Vitamin D–VDR signaling inhibits Wnt/β-Catenin–mediated melanoma progression and promotes antitumor immunity
MX 2 is a novel regulator of cell cycle in melanoma cells
A higher percentage of stroma within primary melanomas is associated with a protective effect on melanoma-specific survival
Transcriptomic analysis reveals prognostic molecular signatures of stage I melanoma
ctDNA as a noninvasive monitoring tool in metastatic melanoma
Genetic and environmental determinants of immune response to cutaneous melanoma
Application of Circulating cell-free tumor DNA profiles for therapeutic monitoring and outcome prediction in genetically heterogeneous metastatic melanoma
MYCexpression and smoking as drivers of failure of immune response to melanoma
Primary melanoma expression of the vitamin D receptor (VDR) is protective for melanoma survival and is associated with increased tumor immune response, decreased Wnt/B-catenin signaling and tumor proliferation
β-Catenin–mediated immune evasion pathway frequently operates in primary cutaneous melanomas
Identification of a gene signature for discriminating metastatic from primary melanoma using a molecular interaction network approach
Comparative genomics reveals that loss of lunatic fringe (LFNG) promotes melanoma metastasis
A screen for combination therapies in BRAF/NRAS wild type melanoma identifies nilotinib plus MEK inhibitor as a synergistic combination
Genomic expression differences between cutaneous cells from red hair color individuals and black hair color individuals based on bioinformatic analysis
Consensus of melanoma gene expression subtypes converges on biological entities
Independent replication of a melanoma subtype gene signature and evaluation of its prognostic value and biological correlates in a population cohort
The clinicopathological and gene expression patterns associated with ulceration of primary melanoma
Targeting human apurinic/apyrimidinic endonuclease 1 (APE1) in phosphatase and tensin homolog (PTEN) deficient melanoma cells for personalized therapy
Patterns of expression of DNA repair genes and relapse from melanoma
Gene expression profiling of paraffin-embedded primary melanoma using the DASL assay identifies increased osteopontin expression as predictive of reduced relapse-free survival